School of Medicine
Showing 1-50 of 1,309 Results
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Raya Saab
Lindhard Family Professor of Pediatric Cancer Biology
BioOur laboratory focuses on investigating molecular mechanisms of oncogene-induced tumorigenesis and tumor suppressor pathways, and oncogenic signaling in the pediatric solid tumor rhabdomyosarcoma. Our earlier work identified the tumor suppressors p53 and p18Ink4c as inhibitors of Cyclin D1-driven tumorigenesis in a pineoblastoma model, through senescence induction, and highlighted distinct roles for the the RB and p53 pathways in induction and maintenance of oncogene-induced senescence. We also identified CDK2 as a potential target for inducing senescence in premalignant lesions to inhibit tumor progression.
Our current focus is on studying oncogenic signaling and tumor suppression in the childhood tumor rhabdomyosarcoma, to identify key mediators of invasion and metastasis, which is the most common cause of treatment failure clinically. We use preclinical in vitro and in vivo models, including murine and human cell lines, and mouse models of disease.
We have recently uncovered a paracrine role for rhabdomyosarcoma-secreted exosomes in impacting biology of stromal cells. Rhabdomyosarcoma-derived exosomes carry specific miRNA cargo that imparts an invasive and migratory phenotype on normal recipient fibroblasts, and proteomic analysis revealed specific and unique pathways relevant to the two different molecular rhabdomyosarcoma subtypes that are driven by distinct oncogenic pathways. We identified that the driver oncogene in fusion-positive rhabdomyosarcoma, PAX3-FOXO1, modulates exosome cargo to promote invasion, migration, and angiogenic properties, and identified specific microRNA and protein cargo acting as effectors of PAX3-FOXO1 exosome-mediated signaling, including modulation of oxidative stress response and cell survival signaling.
Our ongoing work is focused on interrogating specific paracrine signaling pathways and molecular mechanisms of metastatic disease progression in rhabdomyosarcoma, for potential therapeutic targeting. -
Chiara Sabatti
Professor of Biomedical Data Science and of Statistics
Current Research and Scholarly InterestsStatistical models and reasoning are key to our understanding of the genetic basis of human traits. Modern high-throughput technology presents us with new opportunities and challenges. We develop statistical approaches for high dimensional data in the attempt of improving our understanding of the molecular basis of health related traits.
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Suzanne Michelle Sachsman, MD
Clinical Assistant Professor, Dermatology
Clinical Assistant Professor, DermatologyBioSuzanne Sachsman, M.D., is Clinical Assistant Professor of Dermatology. Dr. Sachsman received her Bachelor of Science degree in engineering from Brown University in 2000. She received her medical degree from the Keck School of Medicine of the University of Southern California in 2008 where she spent one year doing dedicated basic science research studying cancer immunotherapy. She trained in radiation oncology, completing residency at USC and fellowship at the University of Florida Health Proton Therapy Institute, prior to completing her dermatology residency at the University of California, Los Angeles in 2018. Dr. Sachsman is a board certified dermatologist and Fellow of the American Academy of Dermatology. Her clinical interests are general dermatology and complex medical dermatology including acne, psoriasis, atopic dermatitis, high risk non-melanoma skin cancer, pigmented lesions, supportive dermato-oncology, and cutaneous lymphoma.
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Zahra Sadat-Hossieny
Clinical Assistant Professor, Neurology & Neurological Sciences
BioDr. Sadat-Hossieny received her MD from The George Washington University in Washington, DC. She is a native of Ohio and completed her neurology residency at The Ohio State University Wexner Medical Center. She then moved to the San Francisco Bay Area for her Epilepsy Fellowship at Stanford University in 2018. She is currently working as a Clinical Instructor at Stanford University, and is devoting fifty percent of her time to research with Dr. Kimford Meador on cognition in epilepsy, with a focus on women with epilepsy and their children. Her interests lie in using the most up to date medications and technologies to provide optimal medical care to patients.
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Sina Sadeghzadeh
MD Student, expected graduation Spring 2026
BioSina was born in Tehran, Iran and raised in Zanjan, Iran. He came out to Massachusetts to attend Harvard University where he obtained his undergraduate degree cum laude in Neuroscience with a secondary in Economics. In college, Sina conducted wet-lab research under the supervision of Dr. Hugo Bellen, worked as a legal intern in Levy Firestone Muse LLP, and served as a research assistant for Drs. Francis Shen, Steven Levitsky, and Jennifer Hochschild. Sina moved to California (by bike!) to begin medical school at Stanford where he is currently pursuing clinical and basic science research opportunities in the neuroscience domain. Outside of medical school, Sina is an avid cyclist, enjoys going on walks, doing yoga, and learning to salsa dance.
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Joel Anthony Sadler
Adjunct Lecturer, Surgery - Anatomy
BioDr. Joel Sadler, is an educator at Stanford University, serial entrepreneur, and XR + AI technology expert. As adjunct faculty at Stanford he teaches STEAM courses exploring how virtual and augmented reality VR and AI can empower the next generation of creative learners. His research at MIT/Stanford has ranged from wearable prosthetics to educational toys. He is a co-founder of several award winning technology companies including Piper Learning and PatchXR, that pioneer learning skills through AI guidance and virtual play. He holds ME/CS degrees from MIT/Stanford and has over 20 publications on the themes of creative computing, and making technology more accessible for all.
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Rebecca Saenz
Clinical Assistant Professor, Pediatrics - Immunology and Allergy
Current Research and Scholarly InterestsAllergy, Immunology, Bioengineering and Biodesign
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Samuel Ricardo Saenz
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Sam Saenz was born in the Bay Area and received his bachelor’s degree in psychology from Stanford University. He completed his medical degree at UC Irvine’s Program in Medical Education for the Latino Community, and he also obtained a Master’s in Public Health from UC Berkeley. After serving as chief psychiatry resident during his psychiatry residency at Stanford, he completed a fellowship in public psychiatry at UC San Francisco. His professional interests include fostering the next generation of diverse mental health providers as well as advancing justice, equity, and inclusion (JEDI) work in academic medicine.
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Lida Safarnejad
Postdoctoral Scholar, Vascular Surgery
BioDr. Lida Safarnejad is a postdoctoral research fellow at Stanford University School of Medicine. She currently works in Ross lab, directed by Dr. Elsie Gyang Ross. Her research focuses on applying Computer Vision and NLP techniques to build models that detect Peripheral Artery Disease PAD. Dr. Safarnejad obtained her Ph.D. in Software and Information Systems from the University of North Carolina at Charlotte. Her doctoral dissertation particularly focused on devising novel computational methods to effectively employ social media in the public health, especially for healthcare crisis management.
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Debra Safer
Associate Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)
Current Research and Scholarly InterestsPrimary research interests include the nature and treatment of eating disorders
(particularly bulimia nervosa and binge eating disorder), the development and treatment of obesity, and the development and treatment of problematic eating patterns in patients following bariatric surgery. -
Marc R. Safran, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Safrans practice focuses on arthroscopic management of hip problems as well as articular cartilage regeneration, shoulder surgery and athletic shoulder and elbow problems. He is actively involved in research in these areas.
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Julien Sage
Elaine and John Chambers Professor of Pediatric Cancer and Professor of Genetics
Current Research and Scholarly InterestsWe investigate the mechanisms by which normal cells become tumor cells, and we combine genetics, genomics, and proteomics approaches to investigate the differences between the proliferative response in response to injury and the hyperproliferative phenotype of cancer cells and to identify novel therapeutic targets in cancer cells.
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Manish Saggar
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsWe are a computational neuropsychiatry lab dedicated to developing computational methods to better understand brain’s overall dynamical organization in healthy and patient populations. We employ algorithms from a wide range of fields, including Applied Mathematics, Econometrics, Machine Learning, Biophysics, and Network Science.
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Gregory Lee Sahlem
Assistant Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology)
BioDr.Sahlem is an Assistant Professor in the Department of Psychiatry and Behavioral Sciences. He is board-certified in general psychiatry and addictions medicine, as well as fellowship-trained in the research and clinical application of neuromodulation-based treatments including repetitive Transcranial Magnetic Stimulation (rTMS), electroconvulsive therapy (ECT), and vagus nerve stimulation (VNS). He additionally has advanced training in the treatment of mood and sleep disorders. In addition to being an active clinician, Dr.Sahlem is a member of the Stanford Brain Stimulation Lab and directs the Addictions Research Section of the Lab.
Major areas of study for Dr.Sahlem include: The development of rTMS as a focused treatment for addictive disorders; the development of a novel form of ECT theorized to have reduced cognitive side effects, Focal Electrically Administered Seizure Therapy (FEAST), and; the further development of rTMS for the treatment of mood disorders.
