School of Medicine
Showing 51-100 of 358 Results
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Jingxun Chen
Postdoctoral Scholar, Genetics
Current Research and Scholarly InterestsUnderstand the molecular impact of sexual interaction on vertebrate organ aging
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Mike Cherry
Professor (Research) of Genetics, Emeritus
Current Research and Scholarly InterestsMy research involves identifying, validating and integrating scientific facts into encyclopedic databases essential for research and scientific education. Published results of scientific experimentation are a foundation of our understanding of the natural world and provide motivation for new experiments. The combination of in-depth understanding reported in the literature with computational analyses is an essential ingredient of modern biological research.
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Melissa Wan Ying Chua
Bioinformatician, Genetics
Current Role at StanfordBioinformatician
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Stanley N. Cohen, MD
Kwoh-Ting Li Professor in the School of Medicine, Professor of Genetics and of Medicine
Current Research and Scholarly InterestsWe study mechanisms that affect the expression and decay of normal and abnormal mRNAs, and also RNA-related mechanisms that regulate microbial antibiotic resistance. A small bioinformatics team within our lab has developed knowledge based systems to aid in investigations of genes.
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Le Cong
Assistant Professor of Pathology (Pathology Research) and of Genetics
Current Research and Scholarly InterestsOur lab develops gene-editing technologies like novel CRISPR systems and large gene insertion techniques for gene&cell therapy. We also leverages these gene-editing tools for single-cell functional screening, to probe molecular mechanisms of cancer and immunological diseases. To accelerate our work, we integrate AI and machine learning to design and evolve gene-editing proteins/RNAs in silico, pushing the frontier that bridges computational and experimental biology.
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Christina Curtis
RZ Cao Professor, Professor of Genetics and of Biomedical Data Science
Current Research and Scholarly InterestsThe Curtis laboratory for Cancer Computational and Systems Biology is focused on the development and application of innovative experimental, computational, and analytical approaches to improve the diagnosis, treatment, and early detection of cancer.
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Kyle Gabriel Daniels
Assistant Professor of Genetics and, by courtesy, of Neurosurgery (Adult Neurosurgery)
BioKyle obtained his BS in Biochemistry from the University of Maryland College Park in 2010, conducting undergraduate research with Dr. Dorothy Beckett, PhD. He obtained his PhD in Biochemistry with a certificate in Structural Biology and Biophysics. His dissertation is titled "Kinetics of Coupled Binding and Conformational Change in Proteins and RNA" and was completed in the laboratory of Dr. Terrence G. Oas, PhD. Kyle performed postdoctoral training with Dr. Wendell A. Lim, PhD at UCSF studying how CAR T cell phenotype is encoded by modular signaling motifs within chimeric antigen receptors.
Kyle's lab is interested in harnessing the principles of modularity to engineer receptors and gene circuits to control cell functions.
The lab will use synthetic biology, medium- and high-throughput screens, and machine learning to: (1) Engineer immune cells to achieve robust and durable responses against various cancer targets, (2) Coordinate behavior of multiple engineered cell types in cancer, autoimmune disease, and payload delivery, (3) Control survival, proliferation, and differentiation of hematopoietic stem cells (HSCs) and immune cells, and (4) Explore principles of modularity related to engineering receptors and gene circuits in mammalian cells. -
Ronald W. Davis
Professor of Biochemistry and of Genetics
Current Research and Scholarly InterestsWe are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.
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Jesse Engreitz
Assistant Professor of Genetics
Current Research and Scholarly InterestsRegulatory elements in the human genome harbor thousands of genetic risk variants for common diseases and could reveal targets for therapeutics — if only we could map the complex regulatory wiring that connects 2 million regulatory elements with 21,000 genes in thousands of cell types in the human body.
We combine experimental and computational genomics, biochemistry, molecular biology, and genetics to assemble regulatory maps of the human genome and uncover biological mechanisms of disease. -
Yanan Feng
Sr. Research Scientist - Basic Life, Genetics
Current Role at StanfordSenior Research Scientist, Department of Genetics, Dr. Stanley N. Cohen's lab
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Andrew Fire
George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Current Research and Scholarly InterestsWhile chromosomal inheritance provides cells with one means for keeping and transmitting genetic information, numerous other mechanisms have (and remain to be) discovered. We study novel cellular mechanisms that enforce genetic constancy and permit genetic change. Underlying our studies are questions of the diversity of inheritance mechanisms, how cells distinguish such mechanisms as "wanted" versus "unwanted", and of the consequences and applications of such mechanisms in health and disease.
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James Ford
Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA damage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.
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Polly Fordyce
Associate Professor of Bioengineering and of Genetics
Current Research and Scholarly InterestsThe Fordyce Lab is focused on developing new instrumentation and assays for making quantitative, systems-scale biophysical measurements of molecular interactions. Current research in the lab is focused on three main platforms: (1) arrays of valved reaction chambers for high-throughput protein expression and characterization, (2) spectrally encoded beads for multiplexed bioassays, and (3) sortable droplets and microwells for single-cell assays.
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Uta Francke
Professor of Genetics and of Pediatrics, Emerita
Current Research and Scholarly InterestsFunctional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care.
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J. Matthew Franklin
Postdoctoral Scholar, Genetics
Current Research and Scholarly InterestsMatt Franklin is investigating the regulation of repetitive DNA arrays in the human genome by transcription factors. This research utilizes super-resolution microscopy, proximity labeling, gene editing, and long-read genomics technologies.
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Judith Frydman
Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics
Current Research and Scholarly InterestsThe long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.
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Margaret T. Fuller
Reed-Hodgson Professor of Human Biology, Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Current Research and Scholarly InterestsRegulation of self-renewal, proliferation and differentiation in adult stem cell lineages. Developmental tumor suppressor mechanisms and regulation of the switch from proliferation to differentiation. Cell type specific transcription machinery and regulation of cell differentiation. Developmental regulation of cell cycle progression during male meiosis.
