Wu Tsai Neurosciences Institute
Showing 501-520 of 619 Results
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Laura Simons
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric)
Current Research and Scholarly InterestsI am a Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine at Stanford University School of Medicine and a clinical psychologist who evaluates and treats youth presenting with chronic pain in the Pediatric Pain Management Clinic (PPMC) at Stanford Children’s Health. My program of research aims to utilize a pain neuroscience psychology approach to gain a mechanistic understanding of cognitive and affective processes in pediatric pain, perform rigorous patient-oriented research that translates targeted assessment into mechanistically informed treatment approaches for optimal clinical care and leverage the ubiquity of digital health to enhance patient access and reach. Central to these goals are projects targeting adolescence and youth adults with chronic pain that encompass defining brain signatures of threat interpretation, evaluating the efficacy of graded exposure (NCT03699007), deriving a biosignature of improvement vs. persistence of pain and disability (NCT04285112), and evaluating the impact of virtual reality on pain rehabilitation (NCT04636177). These studies along with additional work examining the journey of pain care for youth with pain and their parents form a comprehensive research portfolio in the realm of understanding and treating chronic pain in young people. My long-term career goal is to lead a robust research program focusing on alleviating the suffering of youth and emerging adults with chronic pain.
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Upinder Singh
Stanford Medicine Professor of Infectious Disease and Professor of Medicine (Infectious Diseases & Geographic Medicine), Emerita
Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.
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Georgios Skiniotis
Professor of Molecular and Cellular Physiology and of Structural Biology
BioThe Skiniotis laboratory seeks to resolve structural and mechanistic questions underlying biological processes that are central to cellular physiology. Our investigations employ primarily cryo-electron microscopy (cryoEM) and 3D reconstruction techniques complemented by biochemistry, biophysics and simulation methods to obtain a dynamic view into the macromolecular complexes carrying out these processes. The main theme in the lab is the structural biology of cell surface receptors that mediate intracellular signaling and communication. Our current main focus is the exploration of the mechanisms responsible for transmembrane signal instigation in cytokine receptors and G protein coupled receptor (GPCR) complexes.
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Stephen J Smith
Professor of Molecular and Cellular Physiology, Emeritus
Current Research and Scholarly InterestsStephen Smith remains active in the computational microscopy field and is also currently using data science tools to explore new transcriptomic perspectives on signaling by neuropeptides and other neuromodulators in brains of diverse animal species. These exploration have unearthed evidence for a previous unrecognized ubiquity of local neuropeptide signaling and possible critical involvement of such signaling in memory engram formation.
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Matthew Smuck, MD
Professor of Orthopaedic Surgery
On Leave from 06/02/2025 To 07/02/2025Current Research and Scholarly InterestsI direct the Wearable Health Lab at Stanford, investigating medical applications of mobile technology to improve musculoskeletal and neurologic disease detection, treatment and prevention.
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Michael Snyder, Ph.D.
Stanford W. Ascherman Professor of Genetics
On Partial Leave from 12/02/2024 To 12/01/2025Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
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Bruno Passebon Soares, MD
Associate Professor of Radiology (Pediatric)
BioDr. Soares is an Associate Professor of Radiology at Stanford University School of Medicine and serves as the Section Chief of Pediatric Neuroradiology at Lucile Packard Children’s Hospital at Stanford since June 2023.
Born in Brazil, Dr. Bruno P. Soares obtained his medical degree from the Federal University of Rio de Janeiro and completed his residency in Diagnostic Radiology at the Federal University of Sao Paulo. After one year as a Research Fellow at the University of California San Francisco (UCSF), Dr. Soares completed clinical fellowships in Diagnostic Neuroradiology, Pediatric Radiology, and Pediatric Neuroradiology at UCSF, in addition to a clinical fellowship in PET/CT at the Dana-Farber Cancer Institute of Harvard Medical School in Boston. Dr. Soares holds a subspecialty certificate in Neuroradiology from the American Board of Radiology (ABR).
From July 2013 to July 2016, Dr. Soares was an Assistant Professor in the Division of Neuroradiology at Emory University in Atlanta. From August 2016 to November 2018, he worked at the Johns Hopkins University in Baltimore as an Assistant Professor in the Division of Pediatric Radiology and Neuroradiology. From December 2018 to May 2023, Dr. Soares worked at the University of Vermont Medical Center as Associate Professor of Radiology, Division Chief of Neuroradiology, Vice-Chair of Imaging Research, and Co-Director of the MRI Center for Biomedical Imaging.
Dr. Soares has published more than 85 peer-reviewed articles and has been the recipient of the Research Fellow Grant from the Society for Pediatric Radiology and of the Rad_Britestar Award from the Johns Hopkins Department of Radiology. The recognition for his teaching includes the 2013 Outstanding Clinical Fellow / Instructor Teaching Award from the UCSF Department of Radiology, the 2017 Teacher of Year Award from the Johns Hopkins Division of Pediatric Radiology, and the 2017 ASNR International Outreach Professor Program in Ghana.
Dr. Soares currently serves as an Editorial Board Member of Neuroradiology and of the Journal of Neuroimaging, and has served as an Editorial Board Member of the American Journal of Roentgenology (AJR) and of the American Journal of Neuroradiology (AJNR). Dr. Soares served for six years as a member of the ABR Neuroradiology Core Exam Committee, receiving ABR Volunteer Service Awards in 2022 and 2024.
His research has focused on neonatal and pediatric brain imaging. He is currently focused on developing semi-automated algorithms to quantify normal and abnormal brain development, and applying deep learning algorithms for detection of subtle cerebral abnormalities in children with epilepsy. -
Raymond A. Sobel, M.D.
Professor of Pathology
Current Research and Scholarly InterestsWe study cellular and molecular mechanisms of immune-mediated injury in CNS tissues that are affected in multiple sclerosis (MS). We study: 1) tissues of mice with EAE using histology and immunohistochemistry, 2) cross-recognition of neurons by antibodies against myelin proteolipid protein epitopes, and a distinct oligodendrogliopathy induced in mice by the non-protein amino acid azetidine (Aze), (which is found in the human diet); Aze-induced abnormalities mimic those in MS patient CNS tissues
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Hyongsok Tom Soh
W. M. Keck Foundation Professor of Electrical Engineering, Professor of Radiology (Diagnostic Sciences Laboratory) of Bioengineering and, by courtesy, of Chemical Engineering
BioDr. Soh received his B.S. with a double major in Mechanical Engineering and Materials Science with Distinction from Cornell University and his Ph.D. in Electrical Engineering from Stanford University. From 1999 to 2003, Dr. Soh served as the technical manager of MEMS Device Research Group at Bell Laboratories and Agere Systems. He was a faculty member at UCSB before joining Stanford in 2015. His current research interests are in analytical biotechnology, especially in high-throughput screening, directed evolution, and integrated biosensors.
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Olav Solgaard
Director, Edward L. Ginzton Laboratory and Robert L. and Audrey S. Hancock Professor in the School of Engineering
On Leave from 10/01/2024 To 06/30/2025BioThe Solgaard group focus on design and fabrication of nano-photonics and micro-optical systems. We combine photonic crystals, optical meta-materials, silicon photonics, and MEMS, to create efficient and reliable systems for communication, sensing, imaging, and optical manipulation.
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Ivan Soltesz
James R. Doty Professor of Neurosurgery and Neurosciences
BioIvan Soltesz received his doctorate in Budapest and conducted postdoctoral research at universities at Oxford, London, Stanford and Dallas. He established his laboratory at the University of California, Irvine, in 1995. He became full Professor in 2003, and served as department Chair from 2006 to July 2015. He returned to Stanford in 2015 as the James R. Doty Professor of Neurosurgery and Neurosciences at Stanford University School of Medicine. His major research interest is focused on neuronal microcircuits, network oscillations, cannabinoid signaling and the mechanistic bases of circuit dysfunction in epilepsy.
His laboratory employs a combination of closely integrated experimental and theoretical techniques, including closed-loop in vivo optogenetics, paired patch clamp recordings, in vivo electrophysiological recordings from identified interneurons in awake mice, 2-photon imaging, machine learning-aided 3D video analysis of behavior, video-EEG recordings, behavioral approaches, and large-scale computational modeling methods using supercomputers. He is the author of a book on GABAergic microcircuits (Diversity in the Neuronal Machine, Oxford University Press), and editor of a book on Computational Neuroscience in Epilepsy (Academic Press/Elsevier). He co-founded the first Gordon Research Conference on the Mechanisms of neuronal synchronization and epilepsy, and taught for five years in the Ion Channels Course at Cold Springs Harbor. He has over 30 years of research experience, with over 20 years as a faculty involved in the training of graduate students (total of 16, 6 of them MD/PhDs) and postdoctoral fellows (20), many of whom received fellowship awards, K99 grants, joined prestigious residency programs and became independent faculty. -
David A. Spain, MD
Professor of Surgery (General Surgery)
Current Research and Scholarly InterestsOur main areas of interest are
1. clinical research in trauma and critical illness
2. economics of this care
3. PTSD and stress response after critical injury or illness -
David Spiegel
Jack, Lulu and Sam Willson Professor of Medicine
Current Research and Scholarly InterestsDr. Spiegel's research program involves mind/body interactions, including cancer progression, the response to traumatic stress, and the effect of hypnosis on the perception of pain and anxiety.
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Daniel Spielman
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsMy research interests are in the field of medical imaging, particularly magnetic resonance imaging and in vivo spectroscopy. Current projects include MRI and MRS at high magnetic fields and metabolic imaging using hyperpolarized 13C-labeled MRS.
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Konstantina M. Stankovic, MD, PhD, FACS
Bertarelli Foundation Professor and Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsOur investigative efforts are organized along 3 research thrusts:
1. Vestibular schwannoma: uncovering mechanisms of sensorineural hearing loss (SNHL) and identifying better therapies;
2. High-resolution imaging of the inner ear;
3. Novel sensing of and therapies for SNHL.
Considering the complex and multifaceted nature of these challenges, our approach entails tailored solutions that integrate techniques from molecular biology, systems neuroscience, biotechnology, and otologic surgery. -
Creed Stary
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (MSD) and, by courtesy, of Ophthalmology
On Partial Leave from 06/01/2025 To 06/30/2025Current Research and Scholarly InterestsMechanisms promoting neuronal survival following cerebral ischemia-reperfusion injury; utilizing microRNA's to target multiple pathways to promote mitochondrial homeostasis and cell survival; anesthetic neurotoxicity; astrocyte-neuronal interaction
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Kristen K. Steenerson, MD
Clinical Associate Professor, Otolaryngology (Head and Neck Surgery)
Clinical Assistant Professor, Adult NeurologyBioKristen K. Steenerson, MD is a board-certified neurologist with fellowship training in vestibular neurology. She graduated cum laude from Claremont McKenna College, received her MD from the University of Utah, completed neurology residency at Mayo Clinic Arizona, and fellowship at Barrow Neurological Insitute. She directs the Vestibular Balance Disorders Program of the Stanford Balance Center. She has joint appointments in the departments of Otolaryngology--Head and Neck Surgery and Neurology & Neurological Sciences at Stanford. Her clinical interests include vestibular migraine, benign paroxysmal positional vertigo, Ménière's disease, and international neurology.
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Marcia L. Stefanick, Ph.D.
Professor (Research) of Medicine (Stanford Prevention Research Center), of Obstetrics and Gynecology and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsMarcia L. Stefanick, Ph.D is a Professor of Medicine Professor of Obstetrics and Gynecology, and by courtesy, Professor of Epidemiology and Population Health at Stanford University School of Medicine. Dr. Stefanick’s research focuses on chronic disease prevention (particularly, heart disease, breast cancer, osteoporosis, and dementia) in both women and men. She is currently the Principal Investigator the Women’s Health Initiative (WHI) Extension Study, having been the PI of the Stanford Clinical Center of the landmark WHI Clinical Trials and Observational Study since 1994 and Chair of the WHI Steering and Executive Committees from 1998-2011, as well as PI of the WHI Strong and Healthy (WHISH) Trial which is testing the hypothesis that a DHHS-based physical activity intervention, being delivered to a multi-ethnic cohort of about 24,000 WHI participants across the U.S., aged 68-99 when the trial started in 2015, will reduce major cardiovascular events over 8 years, compared to an equal number of “usual activity” controls. Dr. Stefanick is also PI of the Osteoporotic Study of Men (MrOS) which is continuing to conduct clinical assessments of bone and body composition in survivors of an original cohort of nearly 6000 men aged 65 and over in 2001. As founding Director of the Stanford Women’s Health and Sex Differences in Medicine (WHSDM, “wisdom”) Center, she plays a major role in promoting research and teaching on Sex and Gender in Human Physiology and Disease, Women’s Health and Queer Health and Medicine. Dr. Stefanick also plays major leadership roles at the Stanford School of Medicine, including as co-leader of the Population Sciences Program of the Stanford Cancer Institute, Stanford’s NCI-funded comprehensive cancer center.
Dr. Stefanick obtained her B.A. in biology from the University of Pennsylvania, Philadelphia, PA (1974), then pursued her interest in hormone and sex difference research at the Oregon Regional Primate Research Center, after which she obtained her PhD in Physiology at Stanford University, focusing on reproductive physiology and neuroendocrinology, with exercise physiology as a secondary focus. Her commitment to human research led to a post-doctoral fellowship in Cardiovascular Disease Prevention at the Stanford Prevention Research Center, which has been her academic home for nearly 40 years.
