Wu Tsai Neurosciences Institute
Showing 301-350 of 597 Results
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Michael Levitt
Robert W. and Vivian K. Cahill Professor of Cancer Research
Current Research and Scholarly InterestsStanford Professor of Biophysics and Computational Biology, Cambridge PhD and DSc, 2013 Chemistry Nobel Laureate (complex systems), FRS & US National Academy member, I code well for my age.
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Richard Lewis
Professor of Molecular and Cellular Physiology, Emeritus
Current Research and Scholarly InterestsWe study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function. Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development.
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Fei-Fei Li
Sequoia Capital Professor, Denning Co-Director (On Leave) of Stanford HAI, Senior Fellow at HAI and Professor, by courtesy, of Operations, Information and Technology at the Graduate School of Business
On Partial Leave from 01/01/2024 To 12/31/2025Current Research and Scholarly InterestsAI, Machine Learning, Computer Vision, Robotics, AI+Healthcare, Human Vision
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Gordon Li, MD
Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences and of Otolaryngology - Head & Neck Surgery (OHNS)
Current Research and Scholarly Interests1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery. -
Jin Billy Li
Professor of Genetics
Current Research and Scholarly InterestsThe Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.
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Y. Joyce Liao, MD, PhD
Stanford Medicine Professor of Ophthalmology and Professor of Neurology and Neurological Sciences
Current Research and Scholarly InterestsIschemic optic neuropathy
Stem cell transplantation
Optic neuropathy
Optic neuritis
Eye movement disorders
Reading
Parkinson's disease
Multiple sclerosis -
Theresa Lii, M.D., M.S.
Instructor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsEvaluating the analgesic and antidepressant effects of ketamine in humans
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Michael Lim, M.D.
Stanford Medicine Endowed Chair of the Department of Neurosurgery, Professor of Neurosurgery and, by courtesy, of Radiation Oncology, of Medicine, of Otolaryngology - Head & Neck Surgery (OHNS) and of Neurology and Neurological Sciences
BioDr. Lim is the Chair of the Department of Neurosurgery and a board-certified neurosurgeon specializing in brain tumors and trigeminal neuralgia.
Dr. Lim’s clinical interests include the treatment of benign and malignant brain tumors, with special interest in gliomas, meningiomas, metastatic tumors, and skull base tumors. Dr. Lim also specializes in surgical treatments for trigeminal neuralgia. During his time at Johns Hopkins, Dr. Lim built one of the largest brain tumor and trigeminal neuralgia practices and utilized the most advanced surgical technologies and techniques for his patients. As a passionate voice for patient experience, he has been recognized by his peers and patients for his integrity and compassionate care, including a Service Excellence Award from HealthNetwork Foundation.
As a mentor, he has garnered numerous teaching awards, including being honored as an outstanding teacher by Johns Hopkins University School of Medicine. He is actively involved in shaping education for neurosurgery and oncology across the United States and around the world. He is the recipient of the prestigious 2023 Abhijit Guha Award in Neuro-Oncology.
Dr. Lim’s research interests focus on harnessing the immune system to fight cancer. His laboratory focuses on understanding mechanisms of immune evasion by cancer cells. He has successfully translated his findings from the laboratory to the clinics and has conducted and led several large national immunotherapy clinical trials for brain tumors.
Dr. Lim’s bibliography contains well over 300 articles on topics such as immunotherapy for glioblastoma, long-term survival of glioma patients treated with stereotactic radiation, and treatment of neuropathic pain. His work has appeared in Science Translational Medicine, Clinical Cancer Research, Lancet Oncology, Nature Immunology, and many more publications. He also has written 20 book chapters and monographs.
Dr. Lim is a world leader in immunotherapy for brain tumors. In addition to being invited world-wide to give lectures and seminars, he has given platform presentations on the topics of immunotherapy for brain tumors, neurosurgical techniques and management of brain tumors at the American Society of Clinical Oncologists, American Academy of Neurological Surgeons, Radiological Society of North America, Annual Symposium on Brain and Spine Metastases, Congress of Neurological Surgeons, and other meetings. In addition, he has served as platform chairman of the CNS session at the American Society for Clinical Oncology conference.
Dr. Lim is a member of the American Society for Clinical Oncology, Congress of Neurological Surgeons, American Association of Neurological Surgeons, and Society for Neuro-Oncology. Dr. Lim served as the program co-chair of the Society for Neuro-Oncology and CNS section of the American Society for Clinical Oncology. He also served on many executive committees, including the Executive Committee for the Joint Tumor Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons.
Trigeminal neuralgia treatment: https://www.youtube.com/watch?v=-n8nvwkwZik
Trigeminal neuralgia patient stories: https://www.youtube.com/watch?v=kClePRPYlQs&t=1s -
Feng Vankee Lin
Clinical Professor, Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsMy career has been devoted to understanding the neural mechanisms involved in brain aging and brain plasticity, with a special focus on early detection and prevention of Alzheimer’s disease (AD). My research approach integrates principles and findings from cognitive theory, clinical neuroscience, and computational neuroscience.
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Michael Lin
Professor of Neurobiology and of Bioengineering
Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.
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Christian Linder
Professor of Civil and Environmental Engineering and, by courtesy, of Mechanical Engineering
BioChristian Linder is a Professor of Civil and Environmental Engineering and, by courtesy, of Mechanical Engineering. Through the development of novel and efficient in-house computational methods based on a sound mathematical foundation, the research goal of the Computational Mechanics of Materials (CM2) Lab at Stanford University, led by Dr. Linder, is to understand micromechanically originated multi-scale and multi-physics mechanisms in solid materials undergoing large deformations and fracture. Applications include sustainable energy storage materials, flexible electronics, and granular materials.
Dr. Linder received his Ph.D. in Civil and Environmental Engineering from UC Berkeley, an MA in Mathematics from UC Berkeley, an M.Sc. in Computational Mechanics from the University of Stuttgart, and a Dipl.-Ing. degree in Civil Engineering from TU Graz. Before joining Stanford in 2013 he was a Junior-Professor of Micromechanics of Materials at the Applied Mechanics Institute of Stuttgart University where he also obtained his Habilitation in Mechanics. Notable honors include a Fulbright scholarship, the 2013 Richard-von-Mises Prize, the 2016 ICCM International Computational Method Young Investigator Award, the 2016 NSF CAREER Award, and the 2019 Presidential Early Career Award for Scientists and Engineers (PECASE). -
Scott W Linderman
Assistant Professor of Statistics and, by courtesy, of Computer Science
BioScott is an Assistant Professor of Statistics and, by courtesy, Electrical Engineering and Computer Science at Stanford University. He is also an Institute Scholar in the Wu Tsai Neurosciences Institute and a member of Stanford Bio-X and the Stanford AI Lab. His lab works at the intersection of machine learning and computational neuroscience, developing statistical methods to analyze large scale neural data. Previously, Scott was a postdoctoral fellow with Liam Paninski and David Blei at Columbia University, and he completed his PhD in Computer Science at Harvard University with Ryan Adams and Leslie Valiant. He obtained his undergraduate degree in Electrical and Computer Engineering from Cornell University and spent three years as a software engineer at Microsoft before graduate school.
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Wendy Liu, MD, PhD
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsDr. Liu's research interests include the role of mechanosensation in the eye as it relates to the pathophysiology of glaucoma, with the goal of finding new druggable targets in glaucoma treatment.
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James Lock
Eric Rothenberg, MD Professor and Professor, by courtesy, of Pediatrics
On Partial Leave from 10/01/2024 To 09/30/2025Current Research and Scholarly InterestsJames Lock, MD, Ph.D. is Professor of Child Psychiatry and Pediatrics in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine where he has taught since 1993. He is board certified in adult as well as child and adolescent psychiatry. He directs the eating disorder program in Child Psychiatry and is active in treatment research for children and adolescents with eating disorders.
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Kyle Loh
Assistant Professor of Developmental Biology (Stem Cell)
BioHow the richly varied cell-types in the human body arise from one embryonic cell is a biological marvel and mystery. We have mapped how human embryonic stem cells develop into over twenty different human cell-types. This roadmap allowed us to generate enriched populations of human liver, bone, heart and blood vessel cells in a Petri dish from embryonic stem cells. Each of these human cells could regenerate their cognate tissue upon injection into respective mouse models, with relevance to regenerative medicine. In addition to developmental and stem cell biology, we have an emerging interest in exploring deadly biosafety level 4 viruses together with our collaborators.
Kyle attended the County College of Morris and Rutgers, and received his Ph.D. from Stanford (working with Irving Weissman), with fellowships from the Hertz Foundation, National Science Foundation and Davidson Institute for Talent Development. He then continued as a Siebel Investigator, and later, as an Assistant Professor and The Anthony DiGenova Endowed Faculty Scholar at Stanford, where he is jointly appointed in the Department of Developmental Biology and Institute for Stem Cell Biology & Regenerative Medicine. Kyle is a Packard Fellow, Pew Scholar, Human Frontier Science Program Young Investigator and Baxter Foundation Faculty Scholar, and his research has been recognized by the NIH Director's Early Independence Award, Forbes 30 Under 30, Harold Weintraub Graduate Award, Hertz Foundation Thesis Prize and A*STAR Investigatorship. -
Jonathan Z. Long
Associate Professor of Pathology
BioDr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies signaling pathways in mammalian energy metabolism. The long-term goal of this program is to discover new molecules and pathways that can be translated into therapeutic opportunities for obesity, metabolic disease, and other age-associated chronic diseases. Work from the laboratory has been recognized by numerous awards from the Alfred P. Sloan Foundation, the National Institutes of Health, the American Diabetes Association, and the Ono Pharma Foundation. Prior to arriving to Stanford, Dr. Long completed his Ph.D. in Chemistry at Scripps Research and his postdoctoral work at Harvard Medical School.
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Frank M. Longo, MD, PhD
George E. and Lucy Becker Professor of Medicine and Professor, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsClinical interests include Alzheimer's disease and Huntington's disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.
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Billy W Loo, Jr, MD PhD FASTRO FACR
Professor of Radiation Oncology (Radiation Therapy)
Current Research and Scholarly InterestsMy clinical specialty is precision targeted radiotherapy of thoracic cancers.
My research is on developing next-generation ultra-rapid radiation therapy technology (PHASER) and studying the radiobiological effects of FLASH treatment.
My clinical research is on advanced 4-D image-guided radiation therapy and stereotactic ablative radiotherapy (SABR), and functional and metabolic imaging and imaging biomarkers. -
Jaime Lopez, MD
Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy clinical interests are in the areas of Intraoperative Neurophysiologic Monitoring (IOM), clinical neurophysiology, electromyopgraphy and in the use of botulinum toxins in the treatment of neurologic disorders. Our IOM groups research is in the development of new and innovative techniques for monitoring the nervous system during surgical and endovascular procedures and how these alter surgical management and patient outcomes. I am also active in formulating national IOM practice guidelines.
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Irene L. Llorente
Assistant Professor of Neurosurgery
BioOriginally from Spain, Irene L. Llorente joined the Neurosurgery Department at Stanford University in 2022. Following her undergraduate degree in Molecular Biology at the University of Leon in Spain, Dr. Llorente completed a MS in Molecular Biology and Biomedicine and a Ph.D. in Neuroscience between the Universities of Leon (Spain) and Florence (Italy). She conducted a postdoctoral fellowship in the Neurology Department at the David Geffen School of Medicine at UCLA where she also started her independent career as a Research Assistant Professor. Her research interests are largely directed toward understanding the biology of white matter repair in central nervous system (CNS) disorders, with a special emphasis on human glial biology. She is particularly interested in leveraging the current technologies emerging in the stem cell field to develop more efficient and effective stem cell-based therapies for stroke and vascular dementia patients. These stem cell-based therapies will also apply to other CNS disorders including spinal cord injury, multiple sclerosis, and traumatic brain injury in the future.
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Christopher Lowe
Professor of Biology
Current Research and Scholarly InterestsEvolution and development, specifically the evolution of the deuterostomes
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Bingwei Lu
Professor of Pathology
Current Research and Scholarly InterestsWe are interested in understanding how neural stem cells balance their self-renewal and differentiation and how deregulation of this process can result in brain tumor. We are also interested in mechanisms of neurodegeneration in Alzheimers and Parkinsons diseases. We are using both Drosophila and mammalian models to address these fundamental questions.
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Liqun Luo
Ann and Bill Swindells Professor and Professor, by courtesy, of Neurobiology
Current Research and Scholarly InterestsWe study how neurons are organized into specialized circuits to perform specific functions and how these circuits are assembled during development. We have developed molecular-genetic and viral tools, and are combining them with transcriptomic, proteomic, physiological, and behavioral approaches to study these problems. Topics include: 1) assembly of the fly olfactory circuit; 2) assembly of neural circuits in the mouse brain; 3) organization and function of neural circuits; 4) Tool development.
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David Lyons
Professor (Research) of Psychiatry & Behavioral Sciences (General Psychiatry and Psychology-Adult), Emeritus
Current Research and Scholarly InterestsBehavioral neuroscience
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M Bruce MacIver
Professor (Research) of Anesthesiology, Perioperative and Pain Medicine, Emeritus
Current Research and Scholarly InterestsWe study drug effects on the nervous system. Cellular, synaptic and molecular drug actions are investigated using electrophysiological and pharmacological tools in cortical/hippocampal brain slice preparations. We are also interested in mechanisms of neuronal integration and synchronization, especially related to patterns of EEG activity seen in vivo and in brain slices.
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Sean Mackey, M.D., Ph.D.
Redlich Professor, Professor of Anesthesiology, Perioperative, and Pain Medicine (Adult Pain) and, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsMultiple NIH funded projects to characterize CNS mechanisms of human pain. Comparative effectiveness of cognitive behavioral therapy and chronic pain self-management within the context of opioid reduction (PCORI funded). Single session pain catastrophizing treatment: comparative efficacy & mechanisms (NIH R01). Development and implementation of an open-source learning healthcare system, CHOIR (http://choir/stanford.edu), to optimize pain care and innovative research in real-world patients.
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Daniel V. Madison
Professor of Molecular and Cellular Physiology, Emeritus
Current Research and Scholarly InterestsOur underlying forms of activity-dependent synaptic plasticity such as long-term potentiation and long-term depression, and in particular the function and plasticity of Parvalbumin-containing interneurons in neocortex. In the past few years, we have used a combinatorial approach to comparing physiological and anatomical plasticity-induced changes in synapses using electrode recording and Array Tomography in the same neurons.
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Merritt Maduke
Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsMolecular mechanisms of ion chnanels & transporters studied by integration of structural and electrophysiological methods.
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Holden Maecker
Professor (Research) of Microbiology and Immunology
On Partial Leave from 09/15/2024 To 08/31/2025Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.
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Vinit B. Mahajan, MD, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur focus is the development of personalized medicine for eye diseases through translation of our discoveries in proteomics, genomics, and phenomics in humans, mice and tissue culture models.
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Robert Malenka
Nancy Friend Pritzker Professor of Psychiatry and Behavioral Sciences
On Leave from 11/01/2023 To 10/15/2025Current Research and Scholarly InterestsLong-lasting changes in synaptic strength are important for the modification of neural circuits by experience. A major goal of my laboratory is to elucidate the molecular events that trigger various forms of synaptic plasticity and the modifications in synaptic proteins that are responsible for the changes in synaptic efficacy.
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Rachel Manber, PhD
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult)
On Partial Leave from 11/16/2024 To 11/15/2025Current Research and Scholarly InterestsRecent and current projects include
Treatment of insomnia during pregnancy
Treatment of insomnia comorbid with sleep apnea
Use of digital interventions for insomnia among middle age and older adults
Mobile intervention for insomnia among those with alcohol use -
Jessie (Kittle) Markovits
Clinical Associate Professor, Medicine
Clinical Associate Professor (By courtesy), Psychiatry and Behavioral SciencesCurrent Research and Scholarly InterestsHypnosis for perioperative symptom management in elective orthopedic surgery.
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Nicole Martinez-Martin
Assistant Professor (Research) of Pediatrics (Biomedical Ethics) and, by courtesy, of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)
Current Research and Scholarly InterestsNIH/National Institute of Mental Health
K01 MH118375-01A1
“Ethical, Legal and Social Implications in the Use of Digital Technology for Mental Health Applications”
Greenwall Foundation Making a Difference in Bioethics Grant
“Ethical, Legal and Social Implications of Digital Phenotyping” -
Nicole M. Martinez
Assistant Professor of Chemical and Systems Biology and of Developmental Biology
Current Research and Scholarly InterestsThe Martinez lab studies RNA regulatory mechanisms that control gene expression. We focus on mRNA processing, RNA modifications and their roles in development and disease.
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Tarik F. Massoud, MD, PhD
Professor of Radiology (Neuroimaging and Neurointervention)
On Partial Leave from 08/12/2024 To 08/01/2025Current Research and Scholarly InterestsMy current interests are in molecular and translational imaging of the brain especially in neuro-oncology and cerebrovascular diseases, experimental aspects of neuroimaging, clinical neuroradiology, neuroradiological anatomy, and research education and academic training of radiologists and scientists.
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Michaëlle Ntala Mayalu
Assistant Professor of Mechanical Engineering and, by courtesy, of Bioengineering
BioDr. Michaëlle N. Mayalu is an Assistant Professor of Mechanical Engineering. She received her Ph.D., M.S., and B.S., degrees in Mechanical Engineering at the Massachusetts Institute of Technology. She was a postdoctoral scholar at the California Institute of Technology in the Computing and Mathematical Sciences Department. She was a 2017 California Alliance Postdoctoral Fellowship Program recipient and a 2019 Burroughs Wellcome Fund Postdoctoral Enrichment Program award recipient. She is also a 2023 Hypothesis Fund Grantee.
Dr. Michaëlle N. Mayalu's area of expertise is in mathematical modeling and control theory of synthetic biological and biomedical systems. She is interested in the development of control theoretic tools for understanding, controlling, and predicting biological function at the molecular, cellular, and organismal levels to optimize therapeutic intervention.
She is the director of the Mayalu Lab whose research objective is to investigate how to optimize biomedical therapeutic designs using theoretical and computational approaches coupled with experiments. Initial project concepts include: i) theoretical and experimental design of bacterial "microrobots" for preemptive and targeted therapeutic intervention, ii) system-level multi-scale modeling of gut associated skin disorders for virtual evaluation and optimization of therapy, iii) theoretical and experimental design of "microrobotic" swarms of engineered bacteria with sophisticated centralized and decentralized control schemes to explore possible mechanisms of pattern formation. The experimental projects in the Mayalu Lab utilize established techniques borrowed from the field of synthetic biology to develop synthetic genetic circuits in E. coli to make bacterial "microrobots". Ultimately the Mayalu Lab aims to develop accurate and efficient modeling frameworks that incorporate computation, dynamical systems, and control theory that will become more widespread and impactful in the design of electro-mechanical and biological therapeutic machines. -
Jay McClelland
Lucie Stern Professor in the Social Sciences, Professor of Psychology and, by courtesy, of Linguistics and of Computer Science
On Partial Leave from 01/01/2025 To 03/31/2025Current Research and Scholarly InterestsMy research addresses topics in perception and decision making; learning and memory; language and reading; semantic cognition; and cognitive development. I view cognition as emerging from distributed processing activity of neural populations, with learning occurring through the adaptation of connections among neurons. A new focus of research in the laboratory is mathematical cognition and reasoning in humans and contemporary AI systems based on neural networks.
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Susan K. McConnell
Susan B. Ford Professor, Emerita
Current Research and Scholarly InterestsSusan McConnell has studied the cellular and molecular mechanisms that underlie the development of the mammalian cerebral cortex. Her work focused on the earliest events that pattern the developing forebrain, enable neural progenitors to divide asymmetrically to generate young neurons, propel the migration of postmitotic neurons outward into their final positions, and sculpt the fates and phenotypes of the neurons as they differentiate.
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Uel Jackson McMahan
Professor of Neurobiology and of Structural Biology, Emeritus
Current Research and Scholarly InterestsWe are currently investigating mechanisms involved in synaptic transmission and synaptogenesis using electron microscope tomography in ways that provide in situ 3D structural information at macromolecular resolution.
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Jennifer A McNab
Associate Professor (Research) of Radiology (Radiological Sciences Laboratory)
Current Research and Scholarly InterestsMy research is focused on developing magnetic resonance imaging (MRI) methods that probe brain tissue microstructure. This requires new MRI contrast mechanisms, strategic encoding and reconstruction schemes, physiological monitoring, brain tissue modeling and validation. Applications of these methods include neuronavigation, neurosurgical planning and the development of improved biomarkers for brain development, degeneration, disease and injury.