Wu Tsai Neurosciences Institute


Showing 161-180 of 597 Results

  • Emily Fox

    Emily Fox

    Professor of Statistics and of Computer Science
    On Partial Leave from 10/01/2024 To 06/30/2025

    BioEmily Fox is a Professor in the Departments of Statistics and Computer Science at Stanford University. Prior to Stanford, she was the Amazon Professor of Machine Learning in the Paul G. Allen School of Computer Science & Engineering and Department of Statistics at the University of Washington. From 2018-2021, Emily led the Health AI team at Apple, where she was a Distinguished Engineer. Before joining UW, Emily was an Assistant Professor at the Wharton School Department of Statistics at the University of Pennsylvania. She earned her doctorate from Electrical Engineering and Computer Science (EECS) at MIT where her thesis was recognized with EECS' Jin-Au Kong Outstanding Doctoral Thesis Prize and the Leonard J. Savage Award for Best Thesis in Applied Methodology.

    Emily has been awarded a CZ Biohub Investigator Award, Presidential Early Career Award for Scientists and Engineers (PECASE), a Sloan Research Fellowship, ONR Young Investigator Award, and NSF CAREER Award. Her research interests are in modeling complex time series arising in health, particularly from health wearables and neuroimaging modalities.

  • Michael Frank

    Michael Frank

    Benjamin Scott Crocker Professor of Human Biology and Professor, by courtesy, of Linguistics
    On Leave from 10/01/2024 To 06/30/2025

    Current Research and Scholarly InterestsHow do we learn to communicate using language? I study children's language learning and how it interacts with their developing understanding of the social world. I use behavioral experiments, computational tools, and novel measurement methods like large-scale web-based studies, eye-tracking, and head-mounted cameras.

  • Hunter Fraser

    Hunter Fraser

    Professor of Biology

    Current Research and Scholarly InterestsWe study the evolution of complex traits by developing new experimental and computational methods.

    Our work brings together quantitative genetics, genomics, epigenetics, and evolutionary biology to achieve a deeper understanding of how genetic variation shapes the phenotypic diversity of life. Our main focus is on the evolution of gene expression, which is the primary fuel for natural selection. Our long-term goal is to be able to introduce complex traits into new species via genome editing.

  • Shai Friedland

    Shai Friedland

    Professor of Medicine (Gastroenterology and Hepatology)

    Current Research and Scholarly Interests1. Gastrointestinal Endoscopy- Techniques and Outcomes
    2. Noninvasive colorectal cancer screening
    3. Medical device development in gastroenterology

  • Judith Frydman

    Judith Frydman

    Donald Kennedy Chair in the School of Humanities and Sciences and Professor of Genetics

    Current Research and Scholarly InterestsThe long term goal of our research is to understand how proteins fold in living cells. My lab uses a multidisciplinary approach to address fundamental questions about molecular chaperones, protein folding and degradation. In addition to basic mechanistic principles, we aim to define how impairment of cellular folding and quality control are linked to disease, including cancer and neurodegenerative diseases and examine whether reengineering chaperone networks can provide therapeutic strategies.

  • Takako Fujioka

    Takako Fujioka

    Associate Professor of Music

    BioResearch topics include neural oscillations for auditory perception, auditory-motor coupling, brain plasticity in development and aging, and recovery from stroke with music-supported therapy.

    Her post-doctoral and research-associate work at Rotman Research Institute in Toronto was supported by awards from the Canadian Institutes of Health Research. Her research continues to explore the biological nature of human musical ability by examining brain activities with non-invasive human neurophysiological measures such as magnetoencephalography (MEG) and electroencephalography (EEG).

  • Sanjiv Sam Gambhir, MD, PhD

    Sanjiv Sam Gambhir, MD, PhD

    Member, Bio-X

    Current Research and Scholarly InterestsMy laboratory focuses on merging advances in molecular biology with those in biomedical imaging to advance the field of molecular imaging. Imaging for the purpose of better understanding cancer biology and applications in gene and cell therapy, as well as immunotherapy are all being studied. A key long-term focus is the earlier detection of cancer by combining in vitro diagnostics and molecular imaging.

  • Xiaojing Gao

    Xiaojing Gao

    Assistant Professor of Chemical Engineering

    Current Research and Scholarly InterestsHow do we design biological systems as “smart medicine” that sense patients’ states, process the information, and respond accordingly? To realize this vision, we will tackle fundamental challenges across different levels of complexity, such as (1) protein components that minimize their crosstalk with human cells and immunogenicity, (2) biomolecular circuits that function robustly in different cells and are easy to deliver, (3) multicellular consortia that communicate through scalable channels, and (4) therapeutic modules that interface with physiological inputs/outputs. Our engineering targets include biomolecules, molecular circuits, viruses, and cells, and our approach combines quantitative experimental analysis with computational simulation. The molecular tools we build will be applied to diverse fields such as neurobiology and cancer therapy.

  • Chris Garcia

    Chris Garcia

    Younger Family Professor and Professor of Structural Biology

    Current Research and Scholarly InterestsStructural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.

  • Justin Gardner

    Justin Gardner

    Associate Professor of Psychology

    Current Research and Scholarly InterestsHow does neural activity in the human cortex create our sense of visual perception? We use a combination of functional magnetic resonance imaging, computational modeling and analysis, and psychophysical measurements to link human perception to cortical brain activity.

  • Joseph Garner

    Joseph Garner

    Professor of Comparative Medicine and, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsThe medical research community has long recognized that "good well-being is good science". The lab uses an integrated interdisciplinary approach to explore this interface, while providing tangible deliverables for the well-being of human patients and research animals.

  • Brice Gaudilliere

    Brice Gaudilliere

    Associate Professor of Anesthesiology, Perioperative and Pain Medicine (MSD) and, by courtesy, of Pediatrics (Neonatology)

    Current Research and Scholarly InterestsThe advent of high dimensional flow cytometry has revolutionized our ability to study and visualize the human immune system. Our group combines high parameter mass cytometry (a.k.a Cytometry by Time of Flight Mass Spectrometry, CyTOF), with advanced bio-computational methods to study how the human immune system responds and adapts to acute physiological perturbations. The laboratory currently focuses on two clinical scenarios: surgical trauma and pregnancy.

  • Paul George, MD, PhD

    Paul George, MD, PhD

    Associate Professor of Neurology and Neurological Sciences (Adult Neurology) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsCONDUCTIVE POLYMER SCAFFOLDS FOR STEM CELL-ENHANCED STROKE RECOVERY:
    We focus on developing conductive polymers for stem cell applications. We have created a microfabricated, polymeric system that can continuously interact with its biological environment. This interactive polymer platform allows modifications of the recovery environment to determine essential repair mechanisms. Recent work studies the effect of electrical stimulation on neural stem cells seeded on the conductive scaffold and the pathways by which it enhances stroke recovery Further understanding the combined effect of electrical stimulation and stem cells in augmenting neural repair for clinical translational is a major focus of this research going forward.

    BIOPOLYMER SYSTEMS FOR NEURAL RECOVERY AND STEM CELL MODULATION:
    The George lab develops biomaterials to improve neural recovery in the peripheral and central nervous systems. By controlled release of drugs and molecules through biomaterials we can study the temporal effect of these neurotrophic factors on neural recovery and engineer drug delivery systems to enhance regenerative effects. By identifying the critical mechanisms for stroke and neural recovery, we are able to develop polymeric technologies for clinical translation in nerve regeneration and stroke recovery. Recent work utilizing these novel conductive polymers to differentiate stem cells for therapeutic and drug discovery applications.

    APPLYING ENGINEERING TECHNIQUES TO DETERMINE BIOMARKERS FOR STROKE DIAGNOSTICS:
    The ability to create diagnostic assays and techniques enables us to understand biological systems more completely and improve clinical management. Previous work utilized mass spectroscopy proteomics to find a simple serum biomarker for TIAs (a warning sign of stroke). Our study discovered a novel candidate marker, platelet basic protein. Current studies are underway to identify further candidate biomarkers using transcriptome analysis. More accurate diagnosis will allow for aggressive therapies to prevent subsequent strokes.

  • Olivier Gevaert

    Olivier Gevaert

    Associate Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science

    Current Research and Scholarly InterestsMy lab focuses on biomedical data fusion: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. We primarily use methods based on regularized linear regression to accomplish this. We primarily focus on applications in oncology and neuroscience.

  • William Giardino

    William Giardino

    Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)

    Current Research and Scholarly InterestsWe aim to decipher the neural mechanisms underlying psychiatric conditions of stress, addiction, and sleep/circadian dysregulation. Our work uses combinatorial technologies for precisely mapping, monitoring, and manipulating neural circuits that regulate emotional states. We are especially focused on the behavioral functions of neuropeptide molecules acting throughout the circuitry of the extended amygdala- particularly in a brain region called the bed nucleus of the stria terminalis (BNST).

  • Erin Gibson

    Erin Gibson

    Assistant Professor of Psychiatry and Behavioral Sciences (Sleep Medicine)

    Current Research and Scholarly InterestsGlia make up more than half of the cells in the human brain, but we are just beginning to understand the complex and multifactorial role glia play in health and disease. Glia are decidedly dynamic in form and function. Understanding the mechanisms underlying this dynamic nature of glia is imperative to developing novel therapeutic strategies for diseases of the nervous system that involve aberrant gliogenesis, especially related to changes in myelination.