Maternal & Child Health Research Institute (MCHRI)
Showing 51-100 of 996 Results
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Malathi Balasundaram
Clinical Professor, Pediatrics - Neonatology
Current Research and Scholarly InterestsFamily-centered Care in the NICU
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Jennifer K. Bando
Assistant Professor of Microbiology and Immunology
Current Research and Scholarly InterestsMucosal immunology, innate lymphocytes
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Zhenan Bao
K. K. Lee Professor, Senior Fellow at the Precourt Institute for Energy and Professor, by courtesy, of Materials Science and Engineering, of Chemistry, and of Bioengineering
BioZhenan Bao joined Stanford University in 2004. She is currently a K.K. Lee Professor in Chemical Engineering, and with courtesy appointments in Chemistry, Bioengineering and Material Science and Engineering. She was the Department Chair of Chemical Engineering from 2018-2022 and in 2025. She founded the Stanford Wearable Electronics Initiative (eWEAR) and is the current faculty director. Bao received her Ph.D. degree in Chemistry from The University of Chicago in 1995 and joined Bell Labs, Lucent Technologies. She became a Distinguished Member of Technical Staff in 2001. Professor Bao currently has more than 800 refereed publications and more than 80 US patents with a Google Scholar H-index 237.
Bao is a member of the US National Academy of Sciences, National Academy of Engineering, the American Academy of Arts and Sciences and the National Academy of Inventors. Bao was elected a foreign member of the Chinese Academy of Science in 2021. She is a Fellow of AAAS, ACS, MRS, SPIE, ACS POLY and ACS PMSE.
Bao is a member of the Board of Directors for the Camille and Dreyfus Foundation from 2022. She served as a member of Executive Board of Directors for the Materials Research Society and Executive Committee Member for the Polymer Materials Science and Engineering division of the American Chemical Society. She co-founded C3 Nano Co. (acquired by Du Pont) and PyrAmes, which have produced products used in commercial smartphones and hospitals, respectively. Multiple inventions from her lab have been licensed and served as foundational technologies for several additional start-ups.
Bao was a recipient of the VinFuture Prize Female Innovator 2022, ACS Award of Chemistry of Materials 2022, MRS Mid-Career Award in 2021, AICHE Alpha Chi Sigma Award 2021, ACS Central Science Disruptor and Innovator Prize in 2020, ACS Gibbs Medal in 2020, the Wilhelm Exner Medal from the Austrian Federal Minister of Science in 2018, the L'Oreal UNESCO Women in Science Award North America Laureate in 2017. She was awarded the ACS Applied Polymer Science Award in 2017, ACS Creative Polymer Chemistry Award in 2013 ACS Cope Scholar Award in 2011. She is a recipient of the Royal Society of Chemistry Beilby Medal and Prize in 2009, IUPAC Creativity in Applied Polymer Science Prize in 2008.
In Stanford, Bao has pioneered molecular design concepts and fabrication processes to advance the scope and applications of skin-inspired electronics. Her group discovered nano confinement effect of conjugated polymers in polymer blends, which established the fundamental foundation for skin-inspired electronic materials and devices. Her work has resulted in new materials and device solutions for soft robotics, wearable and implantable electronics for precision health, precision mental health and advanced tools for understanding neuroscience and treatment of neurodegenerative diseases. Building on chemical insights, her group has developed foundational materials and devices that enabled a new generation of skin-inspired soft electronics. They provide unprecedented opportunities for understanding human health through developing monitoring, diagnosis and treatment tools. Some examples include: a neuromorphic e-skin that can sense force and temperature and directly communicate with brain, a wireless wound healing patch, a soft NeuroString for simultaneous neurochemical monitoring in the brain and gut, soft high-density electrophysiological recording array, a meta-learned skin sensor for detailed body movements, a reconfigurable self-healing electronic skin. -
Maria Barna
Associate Professor of Genetics
Current Research and Scholarly InterestsThe Barna Lab studies how gene expression is controlled at the level of translation to shape development, regeneration, and disease.For decades, ribosomes were viewed as uniform molecular machines that passively translate genetic information. Our work helped overturn this paradigm by demonstrating that ribosomes can differ in composition and function, giving rise to specialized translation programs that regulate cell fate and organismal development. By integrating genomics, mass spectrometry,
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Leandra A. Barnes, MD
Instructor, Dermatology
BioDr. Barnes is a board-certified dermatologist who provides care at Stanford Health Care Dermatology Clinics in Redwood City and Emeryville. She is also an Instructor of Dermatology within the Department of Dermatology at Stanford School of Medicine.
Dr. Barnes specializes in diagnosing and treating a broad range of skin conditions, including hidradenitis suppurativa, skin cancer, and conditions that disproportionally impact people of color. As Co-Director of the Stanford Medicine Hidradenitis Suppurativa Specialty Clinic, her clinical focus includes maximizing awareness of and care options for this condition. Dr. Barnes is also the Founding Director of the Stanford Medicine Skin of Color Program and Director of Advocacy, Equity, and Inclusion in the Department of Dermatology at Stanford Medicine.
Dr. Barnes’ clinical research focuses on identifying the underlying mechanisms associated with the onset and progression of hidradenitis suppurativa. These efforts include research on access to care among different patient populations and studies identifying immune-mediated characteristics of the condition. She is also engaged in efforts to promote broader and more effective outreach initiatives to drive melanoma awareness among minority populations and young children.
Dr. Barnes has published her work in numerous peer-reviewed journals, including the Journal of Investigative Dermatology, JAMA Dermatology, and the Journal of the American Academy of Dermatology. She has also been an invited guest speaker at national and international meetings, including those for the Society of Investigative Dermatology and the World Congress of Dermatology. -
Patrick Barnes
Professor of Radiology (Pediatric Radiology) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsAdvanced imaging, including magnetic resonance imaging, of injury to the developing central nervous system; including fetal, neonatal, infant and young child; and, including nonaccidental injury (e.g. child abuse).
See Biosketch, CV for details. -
Donald Barr
Professor (Teaching) of Pediatrics (General Pediatrics), Emeritus
BioDonald Barr is a Professor of Pediatrics in the Stanford School of Medicine, and Professor by Courtesy in the Graduate School of Education. He teaches in the Undergraduate Program in Human Biology, where he helped to found Human Biology's curriculum in health policy. His research has studied the effect of the organizational structure of the U.S. medical care delivery system on the quality of primary care. He has also studied cultural and linguistic barriers to health care access for low-income patients, and factors associated with higher rates of attrition from pre-medical studies among minority students at Stanford and other universities. The fourth edition of his book, Introduction to U.S. Health Policy: The Organization, Financing, and Delivery of Health Care in America, was published in 2016. The third edition of his book, Health Disparities in the United States: Social Class, Race, Ethnicity and the Social Determinants of Health, was published in 2019. In June 2003 Dr. Barr was awarded the Lloyd W. Dinkelspiel Award for Distinctive Contribution to Undergraduate Education at Stanford University. In 2006 he received the Miriam Aaron Roland Prize, which recognizes Stanford faculty who engage and involve students in integrating academic scholarship with significant and meaningful volunteer service to society.
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Richard Barth
Professor of Radiology (Pediatric Radiology) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly InterestsMagnetic Resonance Imaging and Sonographic diagnosis of fetal anomalies.
Focus interest in the diagnosis and conservative (non-surgical and minimal radiation) management of congenital broncho pulmonary malformations.
Imaging of appendicitis in children.
Sonography of the pediatric testis. -
Dorsey Bass
Associate Professor of Pediatrics (Gastroenterology), Emeritus
Current Research and Scholarly InterestsOur laboratory is interested in the pathophysiology, immunology, and epidemiology of viral gastroenteritis.
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Hannah Bassett
Clinical Associate Professor, Pediatrics
Current Research and Scholarly InterestsUnderstanding how to implement real time patient-centered healthcare cost transparency in the acute care setting and how this transparency effects patient and system-level outcomes.
Understanding how to best decrease unnecessary variation in clinical care through implementation of clinical effectiveness tools. -
Glaivy Batsuli, MD
Associate Professor of Pediatrics (Hematology/Oncology)
Current Research and Scholarly InterestsHemophilia is a rare inherited X-linked bleeding disorder characterized by the deficiency of blood clotting proteins factor VIII or factor IX. These individuals are at risk for spontaneous bleeds and trauma or surgery-induced bleeding. There have been remarkable advancements in the management of hemophilia to prevent these bleeding episodes and improve quality of life. However, the presence of neutralizing antibodies, called inhibitors, still dictates access to novel therapies such as factor replacement for bleed management and now FDA-approved gene therapies. The Batsuli Lab is focused on elucidating mechanisms of the immune response to blood coagulation proteins in bleeding disorders in order to develop strategies and therapeutics for inhibitor prevention and tolerance induction.
Dr. Batsuli's clinical research interests also include clinical trial participation for novel therapeutics & interventions in bleeding disorders such as hemophilia and von Willebrand disease in addition to coagulation issues & outcomes in ultra-rare bleeding disorders and sickle cell disease. -
Fiona Baumer
Assistant Professor of Neurology (Pediatric Neurology)
Current Research and Scholarly InterestsCauses of Disturbed Cognition in Pediatric Epilepsy
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Philip Beachy
The Ernest and Amelia Gallo Professor, Professor of Urology, of Developmental Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsFunction of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
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Barry Behr, Ph.D., H.C.L.D.
Professor of Obstetrics and Gynecology (Reproductive Endocrinology and Infertility), Emeritus
Current Research and Scholarly InterestsDevelopment of improved embryo culture conditions in vitro. Blastocyst cultures. Embryo metabolism in vitro. Embryo maternal dialogue. Clinical application and integration of extended embryo culture systems. Monozygotic twinning. Prevention of multiple pregnancy. Sperm motility enhancers. Fluorescent and non-fluorescent markers of sperm morphology and viablility. Oocyte cryopreservation. Fertility preservation. Improving IVF outcome.
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Gill Bejerano
Professor of Developmental Biology, of Computer Science and of Pediatrics (Genetics)
Current Research and Scholarly Interests1. Automating monogenic patient diagnosis.
2. The genomic signatures of independent divergent and convergent trait evolution in mammals.
3. The logic of human gene regulation.
4. The reasons for sequence ultraconservation.
5. Cryptogenomics to bridge medical silos.
6. Cryptogenetics to debate social injustice.
7. Managing patient risk using machine learning.
8. Understanding the flow of money in the US healthcare system. -
Eran Bendavid
Professor of Medicine (Primary Care and Population Health), of Health Policy, Senior Fellow at the Woods Institute for the Environment and, by courtesy, at the Freeman Spogli Institute for International Studies
Current Research and Scholarly InterestsEffect of global health policies on health of individuals in developing countries, global health, HIV and TB.
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Catherine Benedict, PhD
Clinical Associate Professor, Psychiatry and Behavioral Sciences - Medical Psychiatry
Current Research and Scholarly InterestsMy research focuses on improving cancer survivorship through better understanding of long-term health outcomes and through the development of theoretically driven, evidence-based behavioral interventions to improve adjustment, risk management, and quality of life. To this end, I lead studies aimed to guide and support patient decision-making and self-management after cancer. Much of my work focuses on the experiences of young adults affected by cancer.
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William Benitz
Philip Sunshine, M.D., Professor in Neonatology, Emeritus
Current Research and Scholarly InterestsNeonatology, patent ductus arteriosus, pulmonary hypertension of the newborn, infant ventilation, neonatal clinical protocols/clinical pathways.
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Jade Benjamin-Chung
Assistant Professor of Epidemiology and Population Health
Current Research and Scholarly InterestsOur research aims to improve population health by creating high quality evidence about what health interventions work in whom and where, when, and how to implement them. Most of our research is focused on environmentally-mediated infectious diseases, including malaria, diarrhea, soil-transmitted helminths, and influenza. Our focus is on improving the health of vulnerable populations from low-resource settings, both domestically and internationally. We use a variety of epidemiologic, computational, and statistical methods, including causal inference and machine learning methods.
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Christopher Bennett
Assistant Professor of Emergency Medicine (Adult Clinical/Academic)
BioI am a board-certified emergency physician and researcher at Stanford, where I bridge clinical practice with health innovation. In addition to being faculty in the Department of Emergency Medicine, I hold affiliations with the Stanford Institute for Human-Centered AI (HAI), the Center for AI in Medicine & Imaging (AIMI), and the Center for Digital Health (CDH).
My work leverages data-informed precision medicine with the goal of transforming healthcare delivery—especially for transmissible infectious diseases. As an NIH funded investigator, I lead a research group that designs solutions to improve patient outcomes and inform policy. I bring extensive experience from training at Duke, Harvard, and Stanford, and a proven track record of leadership from serving on the Society for Academic Emergency Medicine (SAEM) Board of Directors, the SAEM Foundation Board of Trustees.
I am passionate about collaboration to pioneer digital health strategies that revolutionize care and drive tangible impact. -
Rachel Bensen
Clinical Associate Professor, Pediatrics - Gastroenterology
Current Research and Scholarly InterestsMy research focuses on improving health care delivery systems for children, adolescents and young adults with chronic illness and their families. I have particular interests in the development of chronic disease self-management skills, assessment of patient reported outcomes, the transition from pediatric to adult-oriented health care, and comprehensive programs to support families caring for a child with chronic illness.
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David Bergman
Associate Professor of Pediatrics (General Pediatrics) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsMy research has involved the use of new technologies to create different types of patient-doctor transactions. I am also interested in how these new transactions impact clinical care processes. Current work includes the evaluation of a patient portal for children with cystic fibrosis, the use of telemedicine to bring asthma experts into the schools and the attitudes of teens and parents about the use of a secure patient portal for teens.
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Michele Berk, Ph.D.
Associate Professor of Psychiatry and Behavior Sciences (Child and Adolescent Psychiatry and Child Development)
Current Research and Scholarly InterestsThe focus of my research is on adolescent suicidal and self-harm behavior. I am currently one of four Principal Investigators of a multisite NIMH-sponsored RCT of DBT for adolescents at high risk for suicide (NCT01528020: Collaborative Adolescent Research on Emotions and Suicide [CARES], PI: Linehan, McCauley, Berk, & Asarnow) aimed at evaluating the efficacy of DBT with adolescents compared to a combined individual and group supportive therapy control condition (IGST).
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Daniel Bernstein
Alfred Woodley Salter and Mabel G. Salter Endowed Professor of Pediatrics
Current Research and Scholarly Interests1. Using iPSC-derived cardiomyocytes to understand hypertrophic cardiomyopathy and heart failure associated with congenital heart disease.
2. Role of alterations in mitochondrial dycamics and function in normal physiology and disease.
3. Differences between R and L ventricular responses to stress,
4. Immune biomarkers of risk after pediatric VAD implantation.
5. Biomarkers for post-transplant lymphoproliferative disorder. -
Jon Bernstein
Professor of Pediatrics (Genetics) and, by courtesy, of Genetics
Current Research and Scholarly InterestsMy research is focused on the diagnosis, discovery and delineation of rare genetic conditions with a focus on neurodevelopmental disorders. This work includes the application of novel computational methods and multi-omics profiling (whole genome sequencing, long-read DNA sequencing, RNA sequencing, methylomics, metabolomics). I additionally participate in an interdisciplinary project to develop induced pluripotent stem cell and assembloid models of genetic neurodevelopmental disorders.
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Edward Bertaccini
Professor of Anesthesiology, Perioperative and Pain Medicine (MSD), Emeritus
Current Research and Scholarly Interestsmolecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels
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Alice Bertaina MD, PhD
Lorry I. Lokey Professor
Current Research and Scholarly InterestsDr. Bertaina is a highly experienced clinician and will play a key role in supporting Section Chief Dr. Rajni Agarwal and Clinical Staff in the Stem Cell Transplant Unit at Lucile Packard Children’s Hospital. She will also continue her research on immune recovery and miRNA, understanding the mechanisms underlying immune reconstitution, Graft-versus-Host Disease (GvHD), and leukemia relapse after allogeneic HSCT in pediatric patients affected by hematological malignant and non-malignant disorders.
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Carolyn Bertozzi
Baker Family Director of Sarafan ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology
BioCarolyn Bertozzi is the Baker Family Director of Sarafan ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology and of Radiology at Stanford University, and an Investigator of the Howard Hughes Medical Institute. She completed her undergraduate degree in Chemistry from Harvard University in 1988 and her Ph.D. in Chemistry from UC Berkeley in 1993. After completing postdoctoral work at UCSF in the field of cellular immunology, she joined the UC Berkeley faculty in 1996. In June 2015, she joined the faculty at Stanford University and became the co-director and Institute Scholar at Sarafan ChEM-H.
Prof. Bertozzi's research focuses on fundamental studies of disease-associated glycobiology and the development of new therapeutic modalities that target these pathways. Her inventions include bioorthogonal chemistries for in vivo imaging and bioconjugation, work for which she received the 2022 Nobel Prize in Chemistry. As well, her lab has developed next generation antibody-drug conjugates, lysosome-targeting chimeras (LYTACs), antibody-enzyme conjugates and antibody-lectin chimeras. Several of these new therapeutic modalities have been translated into clinical candidates for treatment of cancer and autoimmune diseases.
In addition to the Nobel Prize, Prof. Bertozzi has been recognized with many honors and awards for both her research and teaching accomplishments. For example, she is an elected member of the National Academy of Sciences, the National Academy of Medicine, the National Inventors Academy and the National Academy of Engineering, the American Academy of Arts and Sciences, the German Academy of Sciences Leopoldina, and she is a Foreign Fellow of the Royal Society. In addition, Prof. Bertozzi received the Priestley Medal of the American Chemical Society, the Welch Award, the Wolf Prize in Chemistry, the Heineken Prize, Lemelson-MIT award for inventors, and a MacArthur "Genius Award". -
Vivek Bhalla, MD
Associate Professor of Medicine (Nephrology)
Current Research and Scholarly InterestsDr. Bhalla's two primary research interests are in the role of the kidney in diabetes and hypertension. We use molecular, biochemical, and transgenic approaches to study: (1) mechanisms diabetic kidney disease disease including the role of the endothelium to regulate inflammation and kidney injury; and (2) regulation of tubular transport of glucose, sodium, and potassium. These latter studies have treatment implications in diabetes, kidney disease, and hypertension.
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Rashmi Parekh Bhandari
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsClinical interventions, treatments, and outcomes in pediatric pain management
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Ami Bhatt
Professor of Medicine (Hematology) and of Genetics
Current Research and Scholarly InterestsThe Bhatt lab is exploring how the microbiota is intertwined with states of health and disease. We apply the most modern genetic tools in an effort to deconvolute the mechanism of human diseases.
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Nidhi Bhutani
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsThe long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease.
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Vinod (Vinny) K. Bhutani
Professor of Pediatrics (Neonatology) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsNeonatology; newborn jaundice, bilirubin biology and kernicterus prevention; pulmonary physiology, pulmonary functions and neonatal ventilation. To promote newborn screening for G6PD deficiency in USA.
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Y. Katherine Bianco
Clinical Professor, Obstetrics & Gynecology - Maternal Fetal Medicine
BioMy clinical interest in pregnancies complicated with birth defects has led my underlying research interests in genomic abnormalities in the human trophoblast carrying to faulty placentation. The latter began with initial work during K12 and KO8 funding. I took a great interest in the human placenta as it carries potential advantages over other tissues sources: first, this highly metabolically active organ is the potential source of many transcripts. Second, the placenta forms at a very early stage of embryonic development, potentially allowing detection of primary alterations as compared to secondary changes that may mask the underlying causal phenomena. Finally, studying early placentation may provide targets for development of novel molecular approaches, such as up-regulate or down-regulate genes, the protein products of which could potentially serve as molecular surrogates for diagnosis and treatment of pregnancy complication such as miscarriages, pre-eclampsia, pregnancy induced hypertension and intrauterine growth retardation. This work has led to the first Trisomy 21, Trisomy 18, trisomy 13 cell lines established from human placentas making it possible to apply gene editing in the early stages of human trophoblast development.
As my primary clinical responsibility involves treating patients needing medical care and support through their high risk pregnancies, I am interested in factors that may impact outcomes, such as prenatal screening and diagnosis, maternal heart conditions, labor and delivery management, and safety approaches for the second stage of labor. In investigating length of labor and approaches to shorten the second stage, I have found methods of improving perinatal outcomes in diverse maternal populations.
With regards to my interest in fetal medicine, I have worked in collaboration with other specialists such as radiologists and pediatric cardiologists utilizing imagining studies to assess and determine successful perinatal care and fetal survival. -
Rebecca Blankenburg, MD, MPH
Clinical Professor, Pediatrics
Current Research and Scholarly InterestsMy educational research interests focus on building a more diverse, inclusive and equitable learning environment and helping develop a sense of belonging, professional identity formation, and competence through longitudinal coaching and scholarly mentorship.
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Helen M. Blau
Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
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Catherine Blish
George E. and Lucy Becker Professor in Medicine
Current Research and Scholarly InterestsThe major goal of our research is to gain insight into the prevention and control of HIV and other viral pathogens by studying the interplay between the virus and the host immune response. We investigate the role of various arms of the immune response, but with a particular focus on NK cells. We hope to gain additional insights into control of infectious diseases by studying how pregnancy modulates immune responses.
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Yair Blumenfeld, MD
Professor of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly Interestsprenatal diagnosis, genetics, clinical obstetrics
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Paul D. Blumenthal, MD, MPH
Professor of Obstetrics and Gynecology (Gynecology-Family Planning) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsImproving Access to Family Planning Services in Low Resource Settings:
Through a collaboration with Population Services International, the Stanford Program for International Reproductive Education and Services (SPIRES) provides technical direction in a program designed to improve access to and uptake of family planning, particularly Long Acting Reversible Contraception (LARC) such as IUDs and implants, in 14 developing countries globally. The first year saw insertion of over 280,000 IUDs. -
Alexandria Boehm
Richard and Rhoda Goldman Professor of Environmental Studies, Professor of Oceans and Senior Fellow at the Woods Institute for the Environment
BioI am interested in pathogens in the environment including their sources, fate, and transport in natural and engineered systems. I am interested in understanding of how pathogens are transmitted to humans through contact with water, feces, and contaminated surfaces. My research is focused on key problems in both developed and developing countries with the overarching goal of designing and testing novel interventions and technologies for reducing the burden of disease.
I am also interested broadly in coastal water quality where my work addresses the sources, transformation, transport, and ecology of biocolloids - specifically fecal indicator organisms, DNA, pathogens, and phytoplankton - as well as sources and fate of nitrogen. This knowledge is crucial to formulating new management policies and engineering practices that protect human and ecosystem health at the coastal margins. -
Matthew Bogyo
Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:
1) Design and synthesis of novel chemical probes for serine and cysteine hydrolases.
2) Understanding the role of hydrolases in bacterial pathogenesis and the human parasites, Plasmodium falciparum and Toxoplasma gondii.
3) Defining the specific functional roles of proteases during the process of tumorogenesis.
4) In vivo imaging of protease activity
