School of Medicine
Showing 1-84 of 84 Results
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Chengkun Wang
Postdoctoral Scholar, Pathology
BioChengkun Wang got his PhD from Zhejiang University in 2018.
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Jinglong Wang
Postdoctoral Scholar, Radiation Biology
BioDr. Wang was trained at the Jacques Monod Institute and École Normale Supérieure in Paris, France under the mentorship of Dr. Terence Strick. and obtained his Ph.D. degree from the University of Paris in 2019. He dissected the molecular machinery of human and bacterial NHEJ, and interrogated the mechanism of SpCas9 tolerance to non-specific substrate using single-molecule nanomanipulation tools.
Jinglong’s research in the Frock Lab focuses on DSB-related chromosome topological changes and genomic interactions. -
Mengxiong Wang
Postdoctoral Scholar, Radiation Biology
Current Research and Scholarly Interests1. To investigate the role of p53 in regulating the regression of lung adenocarcinoma and tumor microenvironment.
2. To determine synthetic lethal partner for p53 mutations in the context of lung adenocarcinoma. -
Ziwei Wang
Postdoctoral Scholar, Radiation Therapy
Current Research and Scholarly InterestsMy current work focuses on establishing preclinical platforms to rapidly validate the functional impact of genetic alterations in tumors using both cell and genetically engineered mouse models. We hope this system can accelerate the discovery and translation of novel cancer therapies to patients.
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Kathleen Watson
Postdoctoral Scholar, Psychiatry
BioKathleen (Katie) Watson, Ph.D., received a BA in psychology and a minor in Middle Eastern Studies at New York University. From 2007 to 2012, she served as Chief Operating Officer and Senior Vice President of Microclinic International (MCI). During that time, the organization established public health programs in Jordan, India, Kenya, and the United States. Katie currently serves MCI as Vice-Chairman of the Board of Directors and as a research investigator. In 2020, she received a Ph.D. in Epidemiology at Stanford University while managing research operations at the Stanford Center for Neuroscience and Women’s Health (SCWNH). Katie is currently a postdoctoral scholar candidate in the Stanford Department of Psychiatry and Behavioral Health.
Dr. Watson’s research focuses on integrating causal inference, epidemiologic methods, and additional quantitative tools into psychiatric research. This approach aims to harness the power and scale of these tools to arrive at helpful schemas for psychiatric diagnosis and treatment. -
Brian Wayda
Postdoctoral Scholar, Cardiovascular Medicine
Current Research and Scholarly InterestsHeart transplant policy and outcomes, cost-effectiveness, mathematical modeling
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Emmanuelle Weber
Postdoctoral Scholar, Radiological Sciences Laboratory
BioDr. Emmanuelle Weber is a physicist that obtained a Ph.D. focused on the development and applications of the Dynamic Nuclear Polarization (DNP) method. She allied NMR and EPR spectroscopy studies in her research and recently joined Dr. McNab’s group to work on diffusion MRI.
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Alexis Thomas Weiner
Postdoctoral Scholar, Pathology
Current Research and Scholarly InterestsThe planar cell polarity (PCP) signaling pathway polarizes animal cells along an axis parallel to the tissue plane, and in so doing generates long-range organization that can span entire tissues. Although its core proteins and much about their interactions are known, how PCP signaling occurs at a mechanistic level remains fundamentally mysterious. In my current project I will employ novel genetic methods to dissect the logic underlying how cellular asymmetry arises at a molecular level.
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Chad S. Weldy, M.D., Ph.D.
Postdoctoral Medical Fellow, Cardiovascular Medicine
Fellow in Medicine
Resident in MedicineCurrent Research and Scholarly InterestsAs a physician-scientist in the lab of Dr. Quertermous I work to understand the genetic basis of cardiovascular disease and the transcriptional and epigenomic mechanisms of atherosclerosis. My work is focused across three main areas of cardiovascular genetics and mechanisms of coronary artery disease and smooth muscle biology:
1.CRISPRi screening with targeted perturb seq (TAPseq) to identify novel CAD genes in human coronary artery smooth muscle cells
2.Investigation of the epigenetic and molecular basis of coronary artery disease and smooth muscle cell transition in mice with conditional smooth muscle genetic deletion of CAD genes Pdgfd and Sox9
3.Defining on single cell resolution the cellular and epigenomic features of human vascular disease across vascular beds of differing embryonic origin
My work with Dr. Quertermous is focused on driving discovery in vascular biology by understanding how common genetic variation in humans in complex disease can lead to novel understandings of disease mechanism. With nearly 100,000 GWAS loci discovered across all complex disease, and nearly 300 GWAS loci identified within coronary artery disease, the methods by which GWAS loci are mapped to causal gene is often times limited based proximity to lead SNP without confirmatory functional genomic testing. By using CRISPRi screening in human coronary artery smooth muscle cells with targeted perturb seq (TAPseq), we aim to epigenetically modify specific GWAS loci to then understand enhancer-gene pairs and identify causal CAD genes within the region of a CAD GWAS loci. For identified CAD genes with high confidence for their causality, understanding how CAD genes modify smooth muscle cell state transition within the vascular wall and the epigenomic mechanisms by which this transition occurs is crucial. By using a vascular smooth muscle cell lineage traced mouse model, we can induce smooth muscle specific deletion of CAD genes, Pdgfd and Sox9 to better understand their causal mechanism in vascular disease with single cell RNAseq and single cell ATACseq. Understanding this cell state transition and epigenomic basis of disease is further expanded to human disease with collaboration from our cardiothoracic surgical colleagues. By harvesting human vascular samples at the time of transplant or organ donation, we have the unique ability to understand on a single cell resolution the mechanisms of vascular disease. Importantly, by comparing the cellular gene expression and cell population with scRNAseq in combination with understanding chromatin accessibility on single cell resolution with scATACseq across vascular beds from differing embryonic origin (coronary, ascending aorta, aortic arch, descending thoracic, infrarenal, carotid artery) we can work to understand why there is differential susceptibility to vascular disease across vascular sites and the epigenomic and transcriptional mechanisms that facilitate this differential susceptibility.
This work attempts to apply multiple scientific research arms to ultimately lead to novel understandings of vascular disease and discover important new therapeutic approaches for drug discovery. -
Rain Runxia Wen
Postdoctoral Scholar, Ophthalmology
BioRain Runxia Wen obtained her B.Sc. (Hons) in biology in 2012, and Ph.D. degree in cell and developmental biology in 2018. She joined the Goldberg Lab in the Department of Ophthalmology at Stanford University in 2019. She is currently studying the molecular mechanisms underlying retinal ganglion cell axon growth and optic nerve regeneration.
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Christopher Weyant
Postdoctoral Scholar, Primary Care and Outcomes Research
BioI am a Postdoctoral Scholar in Primary Care and Outcomes Research. I previously completed a PhD in Management Science and Engineering, MS in Bioengineering, and BS in Chemical Engineering at Stanford. In my postdoc, I am developing and applying data-driven methods and models to inform complex health policy decisions surrounding infectious diseases.
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Joseph Wielgosz
Postdoctoral Scholar, Psychiatry
BioJoseph Wielgosz, Ph.D. is a postdoctoral research fellow at the Sierra Pacific MIRECC, VA Palo Alto Healthcare System and Stanford University. His research focuses on using digital health and neuroscience-informed approaches to improve evidence-based treatment of PTSD and related emotion disorders, as well as mindfulness-based interventions for emotional health.
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Kevin Wilkins
Postdoctoral Scholar, Neurology and Neurological Sciences
BioKevin obtained a PhD in Neuroscience from Northwestern University while working in the Physical Therapy and Human Movement Sciences Department and a BS/BA in Psychology and English from Boston College. His dissertation research focused on understanding the neural mechanisms underlying upper extremity impairments in individuals with chronic stroke and subsequent motor improvements following novel interventions. His postdoctoral work at Stanford with Dr. Helen Bronte-Stewart focuses on the neural features associated with gait impairment in individuals with Parkinson's disease using a combination of structural imaging, neurophysiology, and kinematic analysis. He was awarded a Postdoctoral Fellowship for Basic Scientists from the Parkinson's Foundation to investigate the cognitive correlates of gait impairment in Parkinson's disease.
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Alexander Wilson
Postdoctoral Scholar, Radiological Sciences Laboratory
BioACADEMIC FOCUS
● Cardiac anatomy and microstructure using histology and diffusion tensor MRI, and the structural underpinning of cardiac function.
● Ex vivo cardiac MRI, confocal microscopy, image analysis, preclinical models of cardiovascular disease, cardiac Langendorff preparations.
● Assessment of diastolic function and myocardial stiffness
TECHNICAL SKILLS
● Cardiac MRI scanning, animal handling and surgery, preclinical echocardiography, Langendorff heart preparations
● Microscopy, image processing, programming (Matlab, Python, R, ImageJ), cardiac mechanics simulations
2021 WORK
● Wilson et al "Assessment of Microstructural Remodeling in Myocardial InfarctionUsing Advanced Diffusion Metrics" (Submitted) [2022 SCMR]
● Wilson et al "Graph-based Analysis Of Cardiomyocyte Network Connectivity" (Accepted) [2021 AHA:SS]
● Wilson et al "Collagen Remodeling Of Spontaneously Hypertensive Rats Undergoing Quinapril Treatment Measured By Three Dimensional Shape Analysis" [2021 BCVS]
● Wilson et al "Analysis of Location-Dependent Cardiomyocyte Branching" [2021 FIMH]
● Wilson et al "Microstructure-Based Simulation of Myocardial Diffusion Using Extended Volume Confocal Microscopy" [2021 ISMRM]
● Wilson et al "ACE Inhibitor Treatment Normalizes Apparent Diffusion Coefficient in Spontaneously Hypertensive Rats" [2021 SCMR]
2020 WORK
● Wilson et al "Relationship Between Myocyte Branching and Location Within Myocardial Sheetlet" [2020 AHA:SS]
● Wilson et al "Comparison of MRI-Derived Left Ventricular End-Diastolic Pressure-Volume Relationship with Ex Vivo Measurements" [2020 VPH]
● Wilson et al "Myocardial Laminar Organization Is Retained in Angiotensin-Converting Enzyme Inhibitor Treated SHRs" [2020 Exp Mech]
● Wilson et al "Formulation and Characterization of Antithrombin Perfluorocarbon Nanoparticles" [2020 Methods] -
Mollie Woodworth
Instructor, Ophthalmology
Current Research and Scholarly InterestsMany types of blindness result from the neurons of the retina no longer being able to communicate with the brain due to injury or disease. In mammals, the adult retina cannot make new retinal ganglion cells (the neurons that connect the retina with the brain) to replace those that are lost. In my work, I aim to learn about normal development of retinal ganglion cells and, further, to regenerate new retinal ganglion cells if they are lost in adulthood.
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Britt Wray
Postdoctoral Scholar, General Internal Medicine
BioDr. Wray is a Human and Planetary Health Postdoctoral Fellow at the Stanford Center for Innovation in Global Health, Stanford Woods Institute for the Environment and London School of Hygiene & Tropical Medicine. Her research focuses on the mental health impacts of climate change on young people, socioemotional resilience and capacity building for vulnerable communities in the planetary health crisis, and public engagement for improved planetary health. Dr. Wray has a PhD in Science Communication from the University of Copenhagen and is a journalist, speaker, author, and advocate on the topic of eco-anxiety. Her TED talk is called "How climate change affects your mental health". She has hosted and produced several science radio programs, podcasts and television programs for international broadcasters including the BBC and CBC. Dr Wray is an advisor to Climate Cares, a mental health research collaboration between the Institute of Global Health Innovation and the Grantham Institute at Imperial College London.
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Chien-Ting Wu
Postdoctoral Scholar, Microbiology and Immunology
BioI started conducting research as a second-year student in college. I entered a biochemical lab to perform research and had my own project. My topic was Alzheimer's disease, and I focused on the relationship between aggregated amyloid-beta and reactive oxygen species levels in cells. I am very grateful for this particular research experience because it allowed me to realize that I am particularly interested in studying disease-associated proteins on a molecular level. Thus, these early research experiences have been invaluable in shaping my scientific interests and personality.
I decided to pursue my graduate training straight out of college by obtaining my master’s degree. I then decided to join the Chen, I-T. Lab for my graduate research training, where I discovered that a novel recombinant protein, LZ8 cloned from Ganoderma, can inhibit the duplication of cancer cells in vitro and decrease the growth rate of tumors in vivo through regulating the p53/MDM2/mTOR signaling pathway. My findings were published in the journal Carcinogenesis. This was my first first-author paper. During this time, I learned how to become an independent scientist.
After my master’s degree, I spent three years completing my military service as a research assistant in Academia Sinica. I worked under the supervision of Prof. Tang Tang. My research focused on the molecular mechanism of centriole duplication. In my research, I found that CEP120, a ciliopathy protein, is required to promote centriole elongation. Overexpression of CEP120 can induce overly long centrioles. This work was published in the Journal of Cell Biology. This was my second first-author paper. Because of these valuable lab experiences, I began to be fascinated by the centriole and cilium field.
Afterwards, to better understand centriole- and cilia-related human hereditary diseases, I worked as a molecular diagnostician in a molecular diagnosis lab at Oregon Health Science University. I used next-generation sequencing (NGS) to identify gene mutations from ciliopathy patients. During this period, I learned how to run a complete molecular diagnosis, draw blood for running NGS, analyzing patient data, preparing patient reports and designing a novel disease panel to run NGS. This experience provided me with a new perspective and connected the things that I learned in the centriole and cilia field, from biochemistry to molecular biology to clinical diagnosis. Most importantly, this experience allowed me to realize that so many people suffer from ciliopathy disease.
I am currently a Postdoctoral Scholar with Dr. Peter Jackson in the Department of Microbiology and Immunology at Stanford University and collaborate with Dr. Raul Andino in the Department of Microbiology and Immunology at University of California, San Francisco. I study the molecular mechanism of respiratory virus infections, including respiratory syncytial virus (RSV), parainfluenza virus (PIV), and SARS-CoV-2, in the human airway epithelium using cell biological and proteomics approaches to identify potential targets for antiviral drug development.
