Vice Provost and Dean of Research


Showing 541-560 of 2,458 Results

  • Justin Du Bois

    Justin Du Bois

    Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Chemical and Systems Biology

    BioResearch and Scholarship

    Research in the Du Bois laboratory spans reaction methods development, natural product synthesis, and chemical biology, and draws on expertise in molecular design, molecular recognition, and physical organic chemistry. An outstanding goal of our program has been to develop C–H bond functionalization processes as general methods for organic chemistry, and to demonstrate how such tools can impact the logic of chemical synthesis. A second area of interest focuses on the role of ion channels in electrical conduction and the specific involvement of channel subtypes in the sensation of pain. This work is enabled in part through the advent of small molecule modulators of channel function.

    The Du Bois group has described new tactics for the selective conversion of saturated C–H to C–N and C–O bonds. These methods have general utility in synthesis, making possible the single-step incorporation of nitrogen and oxygen functional groups and thus simplifying the process of assembling complex molecules. To date, lab members have employed these versatile oxidation technologies to prepare natural products that include manzacidin A and C, agelastatin, tetrodotoxin, and saxitoxin. Detailed mechanistic studies of metal-catalyzed C–H functionalization reactions are performed in parallel with process development and chemical synthesis. These efforts ultimately give way to advances in catalyst design. A long-standing goal of this program is to identify robust catalyst systems that afford absolute control of reaction selectivity.

    In a second program area, the Du Bois group is exploring voltage-gated ion channel structure and function using the tools of chemistry in combination with those of molecular biology, electrophysiology, microscopy and mass spectrometry. Much of this work has focused on studies of eukaryotic Na and Cl ion channels. The Du Bois lab is interested in understanding the biochemical mechanisms that underlie channel subtype regulation and how such processes may be altered following nerve injury. Small molecule toxins serve as lead compounds for the design of isoform-selective channel modulators, affinity reagents, and fluorescence imaging probes. Access to toxins and modified forms thereof (including saxitoxin, gonyautoxin, batrachotoxin, and veratridine) through de novo synthesis drives studies to elucidate toxin-receptor interactions and to develop new pharmacologic tools to study ion channel function in primary cells and murine pain models.

  • Alfredo Dubra, PhD

    Alfredo Dubra, PhD

    Professor of Ophthalmology

    Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.

  • John Duchi

    John Duchi

    Associate Professor of Statistics, of Electrical Engineering and, by courtesy, of Computer Science

    Current Research and Scholarly InterestsMy work spans statistical learning, optimization, information theory, and computation, with a few driving goals: 1. To discover statistical learning procedures that optimally trade between real-world resources while maintaining statistical efficiency. 2. To build efficient large-scale optimization methods that move beyond bespoke solutions to methods that robustly work. 3. To develop tools to assess and guarantee the validity of---and confidence we should have in---machine-learned systems.

  • Mark Duggan

    Mark Duggan

    Wayne and Jodi Cooperman Professor and Senior Fellow at the Stanford Institute for Economic Policy Research

    BioMark Duggan is a Professor of Economics at Stanford University and a Research Associate at the National Bureau of Economic Research. He received his B.S. and M.S. degrees in Electrical Engineering at M.I.T. in 1992 and 1994, respectively, and his Ph.D. in Economics from Harvard University in 1999. He currently is a Co-Editor at the American Economic Journal: Economic Policy and was previously a Co-Editor at the Journal of Public Economics. Before arriving to Stanford in the summer of 2014, Duggan served on the faculty at the University of Pennsylvania's Wharton School (2011-14), the University of Maryland's Economics Department (2003-11), and the University of Chicago's Economics Department (1999-2003).

    Professor Duggan's research focuses primarily on the effect of government expenditure programs such as Social Security, Medicare, and Medicaid on the behavior of individuals and firms. Some of his more recent research is exploring the effect of federal disability programs on the labor market and of changes to the Medicare and Medicaid programs on the cost and quality of health care. He is also estimating the effect of patent reforms in India on the price and utilization of pharmaceutical treatments. His research has been published in leading academic journals including the American Economic Review, the Journal of Political Economy, and the Quarterly Journal of Economics and has been featured in outlets such as The Economist, the New York Times, and the Wall Street Journal.

    Professor Duggan was the 2010 recipient of the ASHEcon Medal, which is awarded every two years by the American Society of Health Economists to the economist aged 40 and under in the U.S. who has made the most significant contributions to the field of health economics. Along with his co-author Fiona Scott Morton, he received the National Institute for Health Care Management's 2011 Health Care Research Award for their work on Medicare Part D. He was a Fellow of the Alfred P. Sloan Foundation from 2004 to 2006 and a Visiting Fellow at the Brookings Institution from 2006 to 2007. His research has been funded by the National Science Foundation, the National Institutes of Health, the Social Security Administration, and the Robert Wood Johnson Foundation. Duggan served from 2009 to 2010 as the Senior Economist for Health Care Policy at the White House Council of Economic Advisers and has also been an Expert Witness for the U.S. Department of Justice.

  • Laramie Duncan

    Laramie Duncan

    Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)

    Current Research and Scholarly InterestsOur work is at the intersection of statistical genetics, psychiatry, and neuroscience. We use massive datasets and primarily computational approaches to identify mechanisms contributing to mental health problems like schizophrenia and depression. The overall goal of the lab is to discover fundamental information about psychiatric disorders, and ultimately to build more effective approaches to classification, prevention, and treatment.

  • Alexander Dunn

    Alexander Dunn

    Professor of Chemical Engineering

    Current Research and Scholarly InterestsMy lab is deeply interested in uncovering the physical principles that underlie the construction of complex, multicellular animal life.

  • James Dunn

    James Dunn

    Professor of Surgery (Pediatric Surgery)

    Current Research and Scholarly InterestsIntestinal lengthening for short bowel syndrome
    Intestinal stem cell therapy for intestinal failure
    Skin derived precursor cell therapy for enteric neuromuscular dysfunction
    Intestinal tissue engineering

  • Jeffrey Dunn, MD

    Jeffrey Dunn, MD

    Clinical Professor, Adult Neurology

    Current Research and Scholarly InterestsTranslational research in the human application of emerging immunotherapies for neurological disease, focusing on Multiple Sclerosis, CIS, transverse myelitis and Neuromyelitis Optica (NMO). Collaborative research with Stanford and extramural scientific faculty to identify biomarkers of disease activity and treatment response in humans. Clinical trials to assess efficacy of emerging treatments for MS, CIS and NMO.

  • Timothy Durazzo

    Timothy Durazzo

    Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)

    Current Research and Scholarly InterestsThe mission of the Durazzo BRASS lab is to better understand how the interplay between biomedical, psychological and social factors influence treatment outcome in Veterans and civilians seeking treatment for alcohol and substance use disorders. To accomplish this mission, our multidisciplinary team integrates information from advanced neuroimaging, neurocognitive assessment, psychodiagnostic and genotyping methods to identify the biopsychosocial factors associated with relapse and sustained sobriety. Data from Veteran's Administration and Stanford funded Clinical trials are currently being analyzed by the BRASS lab to evaluate the efficacy of repetitive transcranial magnetic stimulation techniques as novel complementary treatments to reduce the high rate of return to hazardous drinking experienced by individuals with alcohol and substance abuse disorders. The ultimate goal of our multidisciplinary research program is to promote the development of more effective biomedical and behavioral treatments for alcohol and substance use disorders through consideration of the brain biology, psychology and social circumstances of each individual.

  • Gozde Durmus

    Gozde Durmus

    Assistant Professor (Research) of Radiology (Molecular Imaging Program at Stanford)

    Current Research and Scholarly InterestsDr. Durmus' research focuses on applying micro/nano-technologies to investigate cellular heterogeneity for single-cell analysis and personalized medicine. At Stanford, she is developing platform technologies for sorting and monitoring cells at the single-cell resolution. This magnetic levitation-based technology is used for wide range of applications in medicine, such as, label-free detection of circulating tumor cells (CTCs) from blood; high-throughput drug screening; and rapid detection and monitoring of antibiotic resistance in real-time. During her PhD, she has engineered nanoparticles and nanostructured surfaces to decrease antibiotic-resistant infections.

  • Carol Dweck

    Carol Dweck

    Lewis and Virginia Eaton Professor and Professor, by courtesy, of Education

    BioMy work bridges developmental psychology, social psychology, and personality psychology, and examines the self-conceptions people use to structure the self and guide their behavior. My research looks at the origins of these self-conceptions, their role in motivation and self-regulation, and their impact on achievement and interpersonal processes.

  • Jennifer Eberhardt

    Jennifer Eberhardt

    Morris M. Doyle Centennial Professor of Public Policy, William R. Kimball Professor at the Graduate School of Business, Professor of Psychology and by courtesy, of Law

    Current Research and Scholarly InterestsMy research is on race and inequality. I am especially interested in examining race and inequality in the criminal justice context. My most recent research focuses on how the association of African Americans with crime might matter at different points in the criminal justice system and how this association can affect us in surprising ways.

  • Asiri Ediriwickrema MD, PhD

    Asiri Ediriwickrema MD, PhD

    Assistant Professor of Medicine (Hematology)

    BioAsiri Ediriwickrema, MD, PhD, is an Assistant Professor of Medicine (Hematology) at the Stanford University School of Medicine. His clinical focus is on the diagnosis, evaluation, and management of patients with myelodysplastic neoplasms and clonal hematopoiesis.

    Dr. Ediriwickrema earned his undergraduate degree in Engineering from the Massachusetts Institute of Technology, his MD (Cum Laude) from Yale University, and his PhD from Stanford University. He completed his residency in Internal Medicine and fellowship in Hematology at Stanford, where he also conducted his doctoral and postdoctoral research in the laboratory of Dr. Ravi Majeti. His research identified novel populations of multipotent progenitor cells in normal hematopoiesis and leukemia stem cells in acute myeloid leukemia (AML).

    He currently leads a systems hematology laboratory that integrates advanced single-cell technologies, computational biology, and functional hematology to study both normal and malignant blood development. His research has been supported by numerous awards, including the NIH Ruth L. Kirschstein National Research Service Award (F32), the American Society of Hematology Scholar Award, and the Edward P. Evans Foundation Young Investigator Award.