Stanford University
Showing 12,601-12,700 of 12,927 Results
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Isabella Young
Affiliate, Psychiatry and Behavioral Sciences
BioIsabella “Bella” Young is a Clinical Psychology doctoral student in the PAU–Stanford Consortium, expected to graduate in 2030. She holds dual Bachelor of Science degrees in Psychology and Criminology, with minors in Sociology and Political Science, from the University of Utah, and earned her Master’s degree in Clinical Psychology from Teachers College, Columbia University.
Bella is committed to integrating empirical research with evidence-based treatment, believing this combination creates the most effective approaches to care. She is a proud alumna of the Perinatal Research on Intergenerational Solutions for Equity (RISE) Laboratory, where she contributed to the Nurse-Family Partnership and Mozambique studies, examining how social inequities become biologically embedded across generations through DNA methylation. She also partnered with Manhattan-based organizations advancing Birthing Justice.
Currently, she continues her work in Columbia’s Maternal & Reproductive Psych Laboratory, where she helped launch a Reproductive Identity study and served as first author on a reproductive identity narrative.
Her research interests focus on perinatal mood and anxiety disorders, reproductive identity, and severe personality pathology in mothers (e.g., borderline personality disorder, postpartum psychosis). Ultimately, Bella aspires to become a clinical psychologist dedicated to bridging research and clinical practice to better support individuals during the perinatal period. -
Peter A Young
MSPA Instructional Faculty, Physician Assistant Studies
BioAs a Visiting Scholar in the Department of Dermatology, I am fortunate to have world-class mentors and colleagues who are committed to a collaborative approach to research. Having a family history of melanoma, I am passionate about investigating skin cancers and other skin conditions. In 2022, I was named Dermatology PA of the Year by the Society of Dermatology Physician Assistants, a national organization with over 4,700 members.
I have co-authored 30 academic publications on a variety of topics including dermatologic surgery, rare skin conditions, allergen content of skin care products, and the state of diversity within the dermatology profession. My writing has appeared in the Journal of the American Medical Association, Journal of the American Academy of Dermatology, Cutis, and elsewhere. My work has also been cited in UpToDate- the world’s most widely used evidence-based encyclopedia for medical professionals.
Most importantly, I believe in exercising empathy and compassion, taking the time to listen to patients as if they were family. To me, there is no greater responsibility or privilege than to be trusted with another person’s health. -
Shady Younis
Instructor, Medicine - Immunology & Rheumatology
BioShady Younis, PhD is an instructor at the division of Immunology and Rheumatology at Stanford University. He received his PhD in Medical Sciences from Uppsala University in Sweden. He later joined Dr. William Robinson’s Lab at Stanford University as Wallenberg postdoctoral fellow, where he characterized the pathogenic role of cytotoxic CD8+ T cells in rheumatoid arthritis. His current research aimed at elucidating the underlying triggers of pathogenic B cell responses in a spectrum of autoimmune diseases, including systemic lupus erythematosus (SLE), rheumatoid arthritis (RA), and multiple sclerosis (MS). He uses computational methodologies alongside cutting-edge high-throughput sequencing technologies to characterize the autoreactive B and T cells. The overarching research objective of his research is to unravel the mechanistic roles of Epstein-Barr Virus (EBV) reactivation in activating and transforming autoreactive B cells in the development of autoimmunity.
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Bo Yu, MD
Associate Professor of Obstetrics and Gynecology (Reproductive Endocrinology and Infertility)
Current Research and Scholarly InterestsDr. Yu’s lab is interested in ovarian physiology and pathology, as well as assisted reproductive technologies (ART).
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Charles Yu MD
Assistant Professor of Ophthalmology
Current Research and Scholarly InterestsCorneal opacity is a leading cause of blindness. Cornea transplantation is at high risk of rejection when there is pre-existing vascularization of the cornea and in pediatric patients. Cornea transplant shortage remains a worldwide problem with millions on waitlists. Our laboratory is developing multiple strategies for treatment of corneal blindness. We are testing advanced materials and designs for keratoprostheses with the goal of reducing complications and easing surgical implantation. We are also developing intraocular electronic display prostheses for bypassing cornea opacity, a novel strategy that could allow for high quality vision without corneal clarity.
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Grace Chen Yu
Clinical Associate Professor, Medicine - Primary Care and Population Health
BioDr. Yu is a modern-day version of the “old-fashioned family doc” who delights in caring for patients from “cradle to grave,” while also promoting the health of her community and developing the future leaders of family medicine. On any particular day, one might find her counseling a long-time smoker on quitting, draining an abscess in clinic, delivering a baby, doing a phone (or sometimes home) visit with one of her elderly patients, lecturing about High-Value Health Care, facilitating a diabetes group visit, singing the praises of coordinated primary care to politicians, discussing end-of-life options with a hospitalized patient, or sharing some of her stories as mother-doctor-teacher with one of her advisees. In 2016, adding one more hat to the mix, Dr. Yu became Program Director of the 24-resident Stanford Health Care - O’Connor Hospital Family Medicine Residency Program. Whereas the old-fashioned family doc was a master at caring for patients at different ages and stages of life, as a modern-day family physician, Dr. Yu is committed to researching ways to do so more effectively and efficiently. She considers it a privilege to be a part of her patients' lives and hopes to help both her patients and her trainees find a path to better health and happiness. To keep herself in great health, Dr. Yu enjoys playing the piano, photography, scuba diving, adventure travel (all the more adventurous with her three children in tow!), and spending time with her family and friends.
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Jingru Yu
Postdoctoral Scholar, Pathology
BioJingru Yu, PhD, MPH, is a postdoctoral researcher at the Department of Pathology. She is interested in developing early diagnostic tools for brain tumors and other solid tumors using epigenomic data and aims to improve the diagnosis and prognosis of tumors.
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Linbo Yu
Clinical Instructor (Affiliated), Pediatrics - Genetics
BioLinbo Yu is a genetic counselor and a founding member of Stanford’s Genetic Testing Optimization Service (GTOS). She received her undergraduate degree from the University of California, Los Angeles in 2007 and her master’s degree in genetic counseling from the University of California, Irvine in 2009. She started her career at Ambry Genetics. In 2014, she became the first lab genetic counselor at Stanford Hospital and helped establish Genetic Testing Optimization Service (GTOS). As a passionate clinical liaison between Stanford Clinical Lab and the ordering providers at Stanford, some of her roles include assisting clinicians with selection of genetic tests, reviewing genetic test orders for clinical appropriateness and educating ordering providers about genetic diseases and test information. Linbo is also a clinical instructor of Department of Pediatrics, and she enjoys clinical supervision of genetic counseling students.
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Mang Yu
BioDr. Yu is contributing to growing the School of Medicine’s portfolio of grants, especially those related to biomedical data science
https://orcid.org/0000-0003-3302-3180 -
Kelley Yuan
Affiliate, Department Funds
Resident in PathologyCurrent Research and Scholarly InterestsPlayfulness
Decision-making
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Kin Min Yuen
Clinical Associate Professor, Psychiatry and Behavioral Sciences - Sleep Medicine
BioDr. Kin Yuen is a board-certified physician in sleep medicine, and is a fellow of the American Academy of Sleep Medicine. She is an associate physician diplomate at University of California at San Francisco, and adjunct faculty member at Stanford University School of Medicine, Department of Psychiatry and Behavioral Services. Before her fellowship in Sleep Medicine, she practiced internal medicine at the Stanford Medical Group. She then spent two years in clinical sleep medicine research at the Stanford Sleep Disorders Center concurrent with acquiring her Masters of Science degree from Stanford University in Health Policy/Health Services Research. She was a current member of Public Safety Committee of the American Academy of Sleep Medicine.
She is also an advisory member to the Continuing Medical Education Committee of School of Sleep Medicine in Palo Alto. Dr. Yuen has been a principal investigator in clinical research of cardiac arrhythmia, medical devices, and has co-authored articles in health economic evaluations, women and sleep disorders. -
Muharrem Yunce, M.D.
Clinical Associate Professor, Pathology
BioDr. Yunce completed his transfusion medicine fellowship at Stanford and then gained invaluable clinical experience with the Malignant Hematology Group at UCSF for two years. After rejoining Stanford, Dr. Yunce started as the Medical Director of Therapeutic Apheresis. In this role, he works with clinicians from various departments, fellows, residents, and nursing staff to ensure life-saving and emergent procedures such as therapeutic plasma exchange (TPE), red cell exchange, plateletpheresis, and leukapheresis are conducted effectively. Additionally, Dr. Yunce oversees extracorporeal photopheresis for solid organ transplant rejection.
Dr. Yunce has been recognized for his contribution to the Department of Pathology as a faculty member in teaching and mentorship.He was selected for Teaching Award in 2023 and Mentor Award by the department and was nominated in 2023 and 2024 for the prestigious Alwin C. Rambar-James B.D. Mark Award for Excellence in Patient Care.
As an active member of the American Society of Apheresis, Dr. Yunce chairs the research subcommittee on TPE utilization in solid organ transplant rejection and desensitization protocols as well as he is member of multiple research subcommittees. -
Ilana Rachel Yurkiewicz
Clinical Associate Professor, Medicine - Primary Care and Population Health
BioDr. Ilana Yurkiewicz is a Clinical Associate Professor of Medicine at Stanford University School of Medicine in the Division of Primary Care and Population Health and Division of Oncology (by courtesy). Board certified in internal medicine, hematology, and oncology, she co-directs Stanford’s Primary Care for Cancer Survivorship Program, an innovative clinic that cares for cancer survivors and patients at elevated risk. She is also an award-winning medical journalist and Stanford’s inaugural Physician-Journalist in Residence.
Her academic and clinical work centers on developing new models of care that bridge oncology and primary care. She has built programs to provide coordinated, longitudinal care for patients during and after cancer treatment and those with inherited cancer predispositions.
As a physician-journalist, she is the author of the nationally acclaimed book Fragmented: A Doctor’s Quest to Piece Together American Health Care (W.W. Norton, 2023). Her writing has also appeared in The Best American Science and Nature Writing, The Atlantic, Scientific American, TIME, STAT, Undark, and other outlets. She received a Folio Award for best healthcare column and was shortlisted for the Cancer Journalism Award.
She is Faculty Director of the annual Big Ideas in Medicine conference, which convenes leaders across fields to examine pressing challenges in health and society. She advises startups focused on cancer survivorship and prevention. As Associate Medical Director of Stanford’s Internal Medicine Clinic, she oversees the largest primary care clinic for Stanford residents. She teaches core concepts of cancer survivorship and primary care to residents, medical students, fellows, and faculty.
Her research focuses on designing new approaches to cancer survivorship delivery, and she leads a research team evaluating their implementation in practice. Her work has been published in the New England Journal of Medicine, Journal of Clinical Oncology, Genetics in Medicine, and other peer-reviewed journals. She has presented nationally at meetings including the Society of General Internal Medicine, American Society of Hematology, and National Society of Genetic Counselors. She has also served on the editorial board of Hematology News.
Earlier in her career, Dr. Yurkiewicz interned with the Presidential Commission for the Study of Bioethical Issues and contributed to white papers on ethical challenges in medicine. She is a member of the American College of Physicians and an associate member of the American Society of Clinical Oncology and American Society of Hematology. -
Maya Yutsis
Affiliate, Adult Neurology
BioMaya Yutsis, Ph.D., ABPP-CN is a Clinical Assistant Professor (Affiliated) in the Department of Neurology and Neurological Sciences at the Stanford University School of Medicine. She is a neuropsychologist at the Stanford Alzheimer's Disease and Research Center (ADRC), Stanford Concussion and Sports Medicine Clinic, and Neuropsychology Service. She received her doctorate in clinical psychology at the Palo AltoUniversity in 2009, completed an APA approved clinical internship in neuropsychology at the Minneapolis VA Medical center and a two-year post doctoral fellowship in Clinical Neuropsychology at the Mayo Clinic in Rochester, MN in 2011. She received her board certification in Clinical Neuropsychology through the American Board of Professional Psychology. Prior to coming to Stanford, she worked as a lead neuropsychologist at the Veterans Affairs Palo Alto Polytrauma Transitional Rehabilitation Program and Geriatric Research Education and Clinical Center (GRECC) Telehealth Neuropsychology clinic and served as a director/preceptor of an APA-approved post-doctoral fellowship Neuropsychology Emphasis Area training program. She is currently a Newsletter Editor of the Society for Clinical Neuropsychology, APA Division 40. Her research interests focus on computerized assessment and interventions for persons with acquired brain injury, sport-related concussion, and mild cognitive impairment (MCI).
PUBLICATIONS (Selected from 15)
Yam, A, Rickards, T, Pawlowski, C, Yutsis, M. (in Press). Interdisciplinary Rehabilitation Approach for Functional Neurological Symptom (Conversion) Disorder: A Case Study. Rehabilitation Psychology
Duchnick, J, Ropacki, S.A., Yutsis, M.V., Petska, K., & Pawlowski, C.A., (2015). Polytrauma Transitional Rehabilitation Programs: Comprehensive, holistic rehabilitation for community integration after brain injury. Psychological Services, 5.
Yochim, B, Beaudreau, S, Fairchild, JK, Yutsis, M, Raymond, N, Friedman, L, Yesavage, J. (2015). A Verbal Naming Test for use with older adults: Development and initial validation. Journal of International Neuropsychological Society, 21, 239-248.
Bergquist, T, Yutsis, M, Sullan, M. (2014). Satisfaction with cognitive rehabilitation delivered via the Internet in persons with acquired brain injury. International Journal of Telerehabilitation, 6(2), 39-50.
Giese-Davis, J., Tamagawa, R., Yutsis, M., Twirbutt, S., Piemme, K., Neri, E., Taylor, C. B., Spiegel, D. (2012) Which symptoms matter? Self-report and observer discrepancies in repressors and high-anxious women with metastatic breast cancer. Journal of Behavioral Medicine, Published online October 20, 2012.
Yutsis, M., Bergquist, T., Micklewright, J. Smigielski, J., Brown, A. (2012) Pre-treatment compensation use is a better correlate of activity limitations than cognitive impairment in persons with acquired brain injury. Brain Injury, 26(11),1297-1306.
Bergquist, T., Micklewright, J., Yutsis, M., Smigielski, J., Gehl, C., Brown, A. (2012) Achievement of client-centered goals by persons with acquired brain injury in comprehensive day treatment is associated with greater vocational and residential independence at discharge and 1 year follow-up. Brain Injury,26(11), 1307-1314
Forducey, PG, Glueckauf, RL, Bergquist, R, Maheu, MM, Yutsis, M (2012). Telehealth for persons with severe functional disabilities and their caregivers: Facilitating self-care management in a home setting. Psychological Services, 9(2), 144-162. -
Lisa Zaba, MD, PhD
Associate Professor of Dermatology
BioLisa Zaba M.D. Ph.D., is an Associate Professor of Dermatology, and Director of the Merkel cell carcinoma (MCC) multi-disciplinary clinic and member of the supportive oncodermatology group at the Stanford Cancer Center. She runs a lab focusing on the immunology of MCC and the treatment and prognostic implications of immune checkpoint inhibitor and targeted therapy rashes. Dr. Zaba completed medical school at Cornell University, PhD in immunology at Rockefeller University, Residency and Post-Doc at Stanford University in 2013.
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Sanno Zack
Clinical Professor, Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsDr. Zack is involved with ongoing research related to the treatment of adolescent and adult trauma (Trauma Focused Cognitive Behavioral Therapy - TF-CBT; Prolonged Exposure - PE), and the effective provision of Dialectical Behavior Therapy (DBT) to adolescent girls and women with disorder of emotion regulation. She additionally studies Acceptance and Commitment Therapy (ACT) for adolescent girls with anxiety. More broadly she is interested in the impact of Evidenced Based Treatments on improving quality of life, and helping individuals find the right match for clinical care. Research is conducted through the Early Life Stress and Pediatric Anxiety Disorders Program at Stanford Children's Hospital and the Stanford Dialectical Behavior Therapy Program.
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Marwa Zafarullah
Postdoctoral Scholar, Neurology and Neurological Sciences
BioDr. Marwa Zafarullah is a dedicated neuroscientist with extensive interdisciplinary experience spanning over 8 years in clinical and pre-clinical research. She holds a Ph.D. in Integrative Genetics and Genomics (IGG) from the University of California Davis, focusing on neuroscience, human genetics, and functional genomics. Before joining Stanford, Dr. Zafarullah harnessed the power of molecular biology with advanced technologies to delve into biomarkers related to the prediction, development, progression, and severity of Fragile X Syndrome and associated disorders.
Dr. Zafarullah's career journey reflects her commitment to advancing scientific knowledge, improving patient care, and positively impacting society through her research and contributions. She thrives in multi-disciplinary teams, aiming to enhance the quality of life for all individuals affected by various neurological conditions. Beyond her professional endeavors, she enjoys communicating complex scientific concepts to diverse audiences. Her continuous pursuit of excellence and her drive to bridge clinical practice and scientific innovation make her a true trailblazer in the field. -
Ken Zafren, MD FAAEM FACEP FAWM
Clinical Professor, Emergency Medicine
Current Research and Scholarly InterestsHigh altitude medicine, AMS, HACE, HAPE, cold injuries, including hypothermia and frostbite, emergency medical services, wilderness medicine, mountain rescue, thrombosis, international medicine, travel medicine, emergency medicine, resuscitation
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Greg Zaharchuk
Professor of Radiology (Neuroimaging and Neurointervention)
On Partial Leave from 03/26/2026 To 08/14/2026Current Research and Scholarly InterestsImproving medical image value using AI
Stroke and dementia imaging
Outcome prediction with AI
Imaging of cerebral hemodynamics with MRI and CT
Noninvasive oxygenation measurement with MRI
PET/MRI in Neuroradiology
Resting-state fMRI for perfusion imaging and stroke -
Dessi Zaharieva
Instructor, Pediatrics - Endocrinology
Current Research and Scholarly InterestsThe 4T (Teamwork, Targets, Technology, and Tight Control) Exercise Study focuses on addressing the attitudes & barriers to exercise for families and newly diagnosed youth with type 1 diabetes (T1D). We are currently establishing feasibility and understanding physical activity patterns and behaviours in newly diagnosed youth with T1D using wearable activity trackers. This work also involves delivering structured exercise education to families and youth with T1D over telehealth.
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Hengameh Zahed, MD, PhD
Clinical Assistant Professor, Adult Neurology
BioDr. Zahed is a board-certified, fellowship-trained neurologist with the Stanford Medicine Movement Disorders Center. She is also a clinical assistant professor in the Department of Neurology and Neurological Sciences.
She diagnoses and treats a wide range of movement disorders including Parkinson’s disease, Huntington’s disease, essential tremor, dystonia, and ataxia. She creates a personalized treatment plan for each of her patients using a variety of treatment options, including pharmacological and non-pharmacological options, deep brain stimulation (DBS) treatment for Parkinson's disease and tremors, and botulinum toxin injections for movement disorders and spasticity.
Prior to joining Stanford University, Dr. Zahed completed a neurology residency and fellowship in movement disorders at University of California, San Francisco (UCSF), where she also earned her MD and PhD in biomedical sciences. Dr. Zahed’s research interests include understanding the genetic and electrophysiological underpinnings of movement disorders and investigating applications of wearable technologies to monitor symptoms and improve the quality of life in patients with movement disorders. She also participates in clinical trials of new therapeutics for Parkinson’s disease and other movement disorders.
Dr. Zahed has published in Movement Disorders, Molecular Genetics & Genomic Medicine, The Journal of Clinical Investigation, American Journal of Human Genetics, Cell, and other peer-reviewed journals. She has presented to her peers at international, national, and regional meetings. These meetings have included the International Congress of Parkinson’s Disease and Movement Disorders, the Hereditary Disease Foundation Symposium, the World Society for Stereotactic and Functional Neurosurgery, and the Society for Neuroscience.
Dr. Zahed is a member of the International Parkinson and Movement Disorders Society. -
Aydin Zahedivash
Affiliate, Department Funds
Fellow in Peds/Clinical InformaticsBioAydin is a physician, educator, and engineer whose interests lie at the intersection of technology, health equity, and children’s health. Aydin completed his undergraduate degree in Biomedical Engineering at the University of Texas at Austin and went on to complete an MD and MBA at the University of Texas at Austin Dell Medical School and McCombs School of Business. He has over 10 years of experience in the medical technology space, having contributed as a researcher, mentor, inventor, and consultant in both the academic and private industry settings. He is a project coach and part of the teaching team within the Biodesign Digital Health Group and is leading a study exploring the role of wearable devices for arrhythmia event monitors in children. He is currently a clinical informatics fellow and is passionate about designing digital solutions to integrate and distribute access to care.
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Natalie M. Zahr
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Major Laboratories)
BioNatalie M. Zahr received a graduate education in the basic sciences including the study of neuro- pharmacology, physiology, and anatomy. After completing her graduate training in electrophysiology, she began a postdoctoral fellowship as a magnetic resonance imaging (MRI) scientist. Her work focuses on translational approaches using in vivo MR imaging and spectroscopy in studies of human with Alcohol Use Disorders (AUD) and in rodent models of alcohol exposure with the goal of identifying mechanisms of alcohol effects on the brain. Her human studies include participants with HIV, those co-morbid for HIV and AUD and recently, aging individuals with mild cognitive impairment (MCI). Her position allows her to explore emerging MR technologies and apply them to test relevant hypotheses. Before joining Stanford, she taught at several local institutions including UC Berkeley extension and Santa Clara University where she enjoyed sharing her knowledge and enthusiasm for learning with students.
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Yulia Zak, MD, FACS
Clinical Assistant Professor, Surgery - General Surgery
BioDr. Yulia Zak earned her medical degree from SUNY Downstate Medical Center before completing general surgery residency at Stanford University and advanced minimally invasive gastrointestinal and bariatric fellowship training at the Massachusetts General Hospital. Dr. Zak is certified by the American Board of Surgery and American Society for Metabolic and Bariatric Surgery. She has also completed the Stanford Surgical Education and Simulation fellowship and was previously an Assistant Program Director for the general surgery residency program at Mount Sinai Beth Israel. Dr. Zak joined the faculty at Stanford in 2018 and is the current Fellowship Associate Program Director. Her current clinical practice is focused on bariatrics, foregut and abdominal wall procedures. Her academic interests include quality improvement, surgical education, and bariatric outcomes.
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Sandra Zaky
Clinical Associate Professor, Radiation Oncology - Radiation Therapy
BioDr. Zaky is a board certified Radiation Oncologist. She received a Bachelor’s of Science in Biomedical/Electrical Engineering at Marquette University. She worked in research and development as an Engineer, and eventually received a Masters of Science in Immunology from Albany Medical College. Her research thesis focused on a novel therapy to treat hormone-receptor positive breast cancer. She continued to study breast cancer with her research during her Radiation Oncology residency; she integrated her research in the laboratory with her clinical research in triple-negative breast cancer. Since completing residency, she has worked as a general radiation oncologist, and her special interests include breast cancer, skin cancer, CNS tumors and stereotactic radiotherapy.
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Isheeta Zalpuri
Clinical Professor, Psychiatry and Behavioral Sciences - Child & Adolescent Psychiatry and Child Development
BioDr. Isheeta Zalpuri is a child, adolescent and adult psychiatrist. She specializes in the treatment of pediatric anxiety and mood disorders.
Dr. Zalpuri has a special interest in faculty development, professional development of trainees, physician well-being and cultural psychiatry. -
Mohammad Asif Zaman
Postdoctoral Scholar, Ophthalmology
Current Research and Scholarly InterestsMy research focuses on trapping and controlled manipulation of sub-micron sized particles. The work included modeling, fabrication and testing of chips that employ optical forces and/or dielectrophoretic forces to trap and transport nanoparticles. Our goal is to develop lab-on-a-chip systems for biomedical and chemical applications.
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Roham Zamanian
James and Yvonne Wood Professor of Pulmonary Vascular Medicine
Current Research and Scholarly Interests1. Development and evaluation of prognostic and diagnostic integral biomarkers in PAH.
2. Prevalence and Treatment of Insulin Resistance in PAH.
3. Role of inflammation and proteomic signature in PAH
4. Development of novel therapeutics (bench to bedside) including FK506 & Elastase Inhibition in PAH.
5. Assessment of Vasoreactivity (gain and loss) in pulmonary arterial hypertension
6. Assessment of microvascular function in PAH. -
Astrid Nicole Zamora
Postdoctoral Scholar, Epidemiology
BioDr. Zamora's work examines how social and environmental contexts shape the three pillars of health, diet, sleep, and physical activity, and influence chronic disease risk. Her research integrates epidemiologic methods with community-based participatory approaches to translate findings into evidence-based public health strategies. Her goal is to advance chronic disease prevention and promote heart-healthy aging among Latino/a communities and underserved populations.
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Richard Zare
Marguerite Blake Wilbur Professor of Natural Science and Professor, by courtesy, of Physics
Current Research and Scholarly InterestsMy research group is exploring a variety of topics that range from the basic understanding of chemical reaction dynamics to the nature of the chemical contents of single cells.
Under thermal conditions nature seems to hide the details of how elementary reactions occur through a series of averages over reagent velocity, internal energy, impact parameter, and orientation. To discover the effects of these variables on reactivity, it is necessary to carry out studies of chemical reactions far from equilibrium in which the states of the reactants are more sharply restricted and can be varied in a controlled manner. My research group is attempting to meet this tough experimental challenge through a number of laser techniques that prepare reactants in specific quantum states and probe the quantum state distributions of the resulting products. It is our belief that such state-to-state information gives the deepest insight into the forces that operate in the breaking of old bonds and the making of new ones.
Space does not permit a full description of these projects, and I earnestly invite correspondence. The following examples are representative:
The simplest of all neutral bimolecular reactions is the exchange reaction H H2 -> H2 H. We are studying this system and various isotopic cousins using a tunable UV laser pulse to photodissociate HBr (DBr) and hence create fast H (D) atoms of known translational energy in the presence of H2 and/or D2 and using a laser multiphoton ionization time-of-flight mass spectrometer to detect the nascent molecular products in a quantum-state-specific manner by means of an imaging technique. It is expected that these product state distributions will provide a key test of the adequacy of various advanced theoretical schemes for modeling this reaction.
Analytical efforts involve the use of capillary zone electrophoresis, two-step laser desorption laser multiphoton ionization mass spectrometry, cavity ring-down spectroscopy, and Hadamard transform time-of-flight mass spectrometry. We believe these methods can revolutionize trace analysis, particularly of biomolecules in cells. -
Christopher K. Zarins
Walter Clifford Chidester and Elsa Rooney Chidester Professor of Surgery, Emeritus
Current Research and Scholarly InterestsHemodynamic factors in atherosclerosis, pathogenesis of, aortic aneurysms, carotid plaque localization and complication, anastomotic intimal hyperplasia, vascular biology of artery wall, computational fluid dynamics as applied to blood flow and vascular disease.
