Stanford University
Showing 10,601-10,700 of 12,907 Results
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Shamsi Soltani
Ph.D. Student in Epidemiology and Clinical Research, admitted Autumn 2021
BioShamsi Soltani is a PhD candidate in the Department of Epidemiology and Population Health and a trainee with the Center for Population Health Sciences, both in the Stanford School of Medicine. For three years, she was a fellow in the NIH T-32 Training in Advanced Data Analytics for Behavioral and Social Sciences (TADA-BSSR) program, supervised by Drs. Abby King and Lorene Nelson. Her dissertation work revolves around modifiable risk factors for suicide in LGBTQ+ populations and is mentored by Dr. Mitchell Lunn.
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Ivan Soltesz
James R. Doty Professor of Neurosurgery and Neurosciences
BioIvan Soltesz received his doctorate in Budapest and conducted postdoctoral research at universities at Oxford, London, Stanford and Dallas. He established his laboratory at the University of California, Irvine, in 1995. He became full Professor in 2003, and served as department Chair from 2006 to July 2015. He returned to Stanford in 2015 as the James R. Doty Professor of Neurosurgery and Neurosciences at Stanford University School of Medicine. His major research interest is focused on neuronal microcircuits, network oscillations, cannabinoid signaling and the mechanistic bases of circuit dysfunction in epilepsy.
His laboratory employs a combination of closely integrated experimental and theoretical techniques, including closed-loop in vivo optogenetics, paired patch clamp recordings, in vivo electrophysiological recordings from identified interneurons in awake mice, 2-photon imaging, machine learning-aided 3D video analysis of behavior, video-EEG recordings, behavioral approaches, and large-scale computational modeling methods using supercomputers. He is the author of a book on GABAergic microcircuits (Diversity in the Neuronal Machine, Oxford University Press), and editor of a book on Computational Neuroscience in Epilepsy (Academic Press/Elsevier). He co-founded the first Gordon Research Conference on the Mechanisms of neuronal synchronization and epilepsy, and taught for five years in the Ion Channels Course at Cold Springs Harbor. He has over 30 years of research experience, with over 20 years as a faculty involved in the training of graduate students (total of 16, 6 of them MD/PhDs) and postdoctoral fellows (20), many of whom received fellowship awards, K99 grants, joined prestigious residency programs and became independent faculty. -
Scott G. Soltys, MD
Professor of Radiation Oncology (Radiation Therapy) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy clinical and research interests focus on the development of new radiation techniques involving stereotactic radiosurgery and radiotherapy for the treatment of malignant and benign tumors of the brain and spine, as well as functional disorders such as trigeminal neuralgia.
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Sulaiman Somani
Affiliate, Department Funds
Fellow in Medicine - Med/Cardiovascular MedicineCurrent Research and Scholarly InterestsSulaiman Somani is passionate about harnessing the power of cardiovascular signals (e.g., electrocardiograms) and large clinical data (e.g., unstructured like clinical notes) with artificial intelligence to create digital health tools to explain important research questions in and develop digital health tools for prevalent problems in Preventive Cardiology and Cardiac Electrophysiology, particularly around atrial fibrillation.
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Barbara Sommer
Associate Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center, Emerita
Current Research and Scholarly InterestsI am interested in the clinical investigation of cognitive stresses during younger adulthood that may give rise to frank intellectual impairment with older age. Examples may include specific kinds of chronically taken medications.
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Hong Song, MD, PhD
Assistant Professor of Radiology (Nuclear Medicine)
BioHong Song received his MD from Tulane University School of Medicine and a Ph.D. in Chemical Engineering from Tulane University. He performed research in targeted radionuclide therapy as a postdoctoral fellow at the Johns Hopkins University. Following medical school, he joined Dual pathway Nuclear Medicine and Diagnostic Radiology residency at Stanford. His current research interests include PSMA PET in biochemically recurrent prostate cancer and DOTATATE PET in PRRT for neuroendocrine tumors.
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Leina'ala Song, MD
Clinical Assistant Professor, Orthopaedic Surgery
BioDr. Song is a double board-certified sports medicine physician with Stanford Health Care Orthopaedics and Sports Medicine. She is a clinical assistant professor in the Department of Orthopaedic Surgery at Stanford University School of Medicine. Dr. Song completed fellowship training in orthopaedics and sports medicine at the University of Washington School of Medicine in Seattle, Washington.
Dr. Song specializes in managing a wide range of sports and musculoskeletal injuries. She performs ultrasound-guided injections including corticosteroid, hyaluronic acid, and PRP. She is also skilled at using high-resolution ultrasound to perform other minimally invasive interventions, such as ultrasound guided percutaneous tenotomies and peripheral nerve hydrodissections. She is currently the primary team physician for numerous Division 1 athletic teams at Stanford University, including men’s volleyball, women’s volleyball, beach volleyball, lacrosse, open weight crew, light weight crew, softball, artistic swim, and sailing.
Dr. Song’s research interests include the long-term outcomes of percutaneous ultrasound-guided tenotomy, orthobiologics, and the health of the female athlete. She has taught sports medicine fellows as well as primary care residents. She has provided sideline coverage at multiple athletic events, as well as pre-participation screenings for professional teams such as the Seattle Seahawks and Seattle Seawolves. -
Geoffrey Sonn
Associate Professor of Urology and, by courtesy, of Radiology (Body MRI)
Current Research and Scholarly InterestsMy interest is in improving prostate cancer diagnosis through MRI and image-targeted prostate biopsy. In collaboration with radiologists at Stanford, we are working to define the optimal role of MRI in prostate cancer. We hope to improve cancer imaging to the point that some men with elevated PSA may safely avoid prostate biopsy. For those who need biopsy, we are evaluating novel MRI-US fusion targeted biopsy, a technique that greatly improves upon the conventional biopsy method.
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Justin L. Sonnenburg
Alex and Susie Algard Endowed Professor
Current Research and Scholarly InterestsThe goals of the Sonnenburg Lab research program are to (i) elucidate the basic mechanisms that underlie dynamics within the gut microbiota and (ii) devise and implement strategies to prevent and treat disease in humans via the gut microbiota. We investigate the principles that govern gut microbial community function and interaction with the host using a broad range of experimental approaches including studies of microbiomes in diverse human cohorts.
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Irene Sonu
Clinical Associate Professor, Medicine - Gastroenterology & Hepatology
BioI am passionate about gut health and strive to provide the best care to my patients. I specialize in complex motility disorders of the gastrointestinal tract. My areas of clinical expertise include achalasia, dysphagia, eosinophilic esophagitis, gastroesophageal reflux disease, gastroparesis, functional dyspepsia, irritable bowel syndrome, and pelvic floor dysfunction. I also see patients in need of fecal microbiota transplant for recurrent C. difficile infection.
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Steven Soo
Clinical Assistant Professor, Medicine
BioSteven Soo, MD, is a Clinical Assistant Professor in the Division of Hospital Medicine at Stanford. Born and raised in the Pacific Northwest, he earned his undergraduate degree in chemical engineering from Oregon State University and began his career in the paper and semiconductor manufacturing industries before pivoting to medicine. Dr. Soo completed medical school and internal medicine residency at New York University Grossman Long Island School of Medicine. In addition to his clinical responsibilities, he has been actively involved in a range of quality improvement and research projects. His academic interests include cardiology, with particular focus on cardio-oncology and advanced heart failure, as well as systems-based strategies for improving patient care and clinical operations.
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Piya Sorcar
Academic Staff - Hourly - CSL, Pediatrics - General Pediatrics
BioDr. Piya Sorcar is the founder and CEO of TeachAids, an Adjunct Professor at Stanford’s School of Medicine, and an Adjunct Lecturer at the Graduate School of Education. She leads a team of world experts in medicine, public health, and education to address some of the most pressing public health challenges.
TeachAids is an award-winning 501(c)(3) nonprofit social venture that creates breakthrough software addressing numerous persistent problems in health education around the world, including HIV/AIDS, concussion, and COVID-19. A pioneer in the development of infectious disease education, TeachAids HIV education software is used in 82 countries. In partnership with the US Olympic Committee’s National Governing Bodies, TeachAids has launched the CrashCourse concussion education product suite, which includes research-based applications available online as a standard video and in virtual reality. CoviDB is their third health education initiative, a community-edited platform organizing resources across a comprehensive set of topics relating to COVID-19 for free public use.
Sorcar received her Ph.D. in Learning Sciences and Technology Design and her M.A. in Education from Stanford University. She graduated summa cum laude from the University of Colorado at Boulder with a B.A. in Economics, B.S. in Journalism, and B.S. in Information Systems. She has been an invited speaker at leading universities such as Columbia, Johns Hopkins, Tsinghua, and Yale. MIT Technology Review named her to its TR35 list of the top 35 innovators in the world under 35 and she was the recipient of Stanford’s Alumni Excellence in Education Award. -
Sarah Sorice, MD
Clinical Assistant Professor, Surgery - Plastic & Reconstructive Surgery
BioDr. Sorice-Virk is a board-certified, fellowship-trained plastic and reconstructive surgeon with the Stanford Health Care Cancer Center and a clinical assistant professor in the Department of Surgery, Division of Plastic & Reconstructive Surgery. She is medical director of the Stanford Health Care Breast Reconstruction Program in the East Bay. Dr. Sorice-Virk completed her medical degree at New York University School of Medicine. She then went on to do her residency in Plastic Surgery and fellowship in Advanced Wound Care at Stanford University School of Medicine. Finally, this was followed by a fellowship in Advanced Reconstructive Microsurgery at the University of Pennsylvania.
Dr. Sorice-Virk’s clinical interests include complex reconstruction after cancer and trauma while keeping optimal aesthetic outcomes as a top priority. She performs a wide range of procedures, including breast reconstruction and other cancer reconstruction such as gynecologic, colorectal and orthopedic among others, breast-conserving surgery, cosmetic plastic surgery, reconstructive plastic surgery, and body contouring. Patients of Dr. Sorice-Virk benefit from a personalized and compassionate care approach. In addition to offering the entire gamut of standard reconstructive modalities, she uses cutting edge surgical techniques, such as perforator flaps (i.e. DIEP flap), hybrid breast reconstruction (i.e. the combination of free flap transfer and implant placement), and breast neurotization to restore breast sensation and in conjunction with the breast surgeons, expanding indications for nipple sparing mastectomies to improve aesthetic outcomes for more patients.
Research interests of Dr. Sorice-Virk include plastic surgery/breast reconstruction outcomes and integrative medicine in plastic surgery. She serves as the principal investigator for multiple research projects and has received grant funding from several organizations.
Her published work includes numerous papers, book chapters, and abstracts, and she has presented her findings at national and international conferences. Additionally, Dr. Sorice-Virk is an ad hoc peer reviewer for Annals of Plastic Surgery and Microsurgery.
Dr. Sorice-Virk is a member of the American Society of Plastic Surgeons and the American Society for Reconstructive Microsurgery. -
Ana Lilia Soto
Youth Development Manager, Psych/Public Mental Health & Population Sciences
Current Role at StanfordYouth Development Manager
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Aline Rocha
INSPIRE Training Manager, Psych/Public Mental Health & Population Sciences
Current Role at StanfordINSPIRE Training Manager
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Alex Sox-Harris, PhD, MS
Professor (Research) of Surgery (Surgery Policy Improvement Research and Education Center)
Current Research and Scholarly InterestsQuality Measurement, Predictive Modeling, Implementation Science,
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David A. Spain, MD
Professor of Surgery (General Surgery)
Current Research and Scholarly InterestsOur main areas of interest are
1. clinical research in trauma and critical illness
2. economics of this care
3. PTSD and stress response after critical injury or illness -
Megan Sparrow
MD Student with Scholarly Concentration in Clinical Research / Women's Health - Sexual & Gender Minority Health, expected graduation Spring 2030
BioI am a medical student at Stanford University School of Medicine with a background in molecular biology and stem cell research. I received my B.S. in Molecular, Cell, and Developmental Biology with a minor in Biomedical Research from UCLA, where I became interested in developmental biology and stem cell-based embryo models through my work in the Clark Lab. After graduation, I joined the Briganti Lab at UC San Diego as a Staff Research Associate and Lab Manager, studying the molecular mechanisms of dilated cardiomyopathy using iPSC-derived cardiomyocytes. Building on these experiences, my current interests center on women’s health, embryo and stem cell research, and reproductive endocrinology and infertility. In my personal time, you will find me at the beach, hiking, baking, or attempting to garden.
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Katie Speirs M.D.
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. Speirs is a practicing Anesthesiologist at Stanford Hospital in Palo Alto, CA. She is a member of the multi-specialty division with a focus on Head and Neck and Thoracic Anesthesia subdivisions. Passionate about education, Dr. Speirs values highly the art of teaching and excellence in clinical care within the medical community. She participates in the education of all levels of student ranging from undergraduate to fellow. She is an advocate for green initiatives and sustainability in healthcare. Dr. Speirs strives to enhance collaboration and communication within the medical field and was involved in the introduction of personalized scrub caps to the operating rooms at Stanford. With a unique blend of medical expertise, dedication to education, and environmental consciousness, Dr. Speirs is at the forefront of shaping a holistic approach to high quality healthcare at Stanford.
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Allyson Spence
Clinical Assistant Professor, Medicine - Oncology
BioAllyson Spence MD, PhD is a Clinical Assistant Professor of Medicine in the Stanford University School of Medicine. She received her MD, PhD in the MSTP program at Vanderbilt University School of Medicine, studying basic mechanisms of transcription using Saccharomyces cerevisiae as a model system in the laboratory of Dr. Tony Weil. She went on to an internship and residency at the University of Pennsylvania before returning to Stanford to complete her Oncology fellowship training. She did a postdoctoral fellowship at Stanford in the department of Molecular Biology under the auspices of Dr. Margaret Fuller, where she was the recipient of a career award.
She has transitioned from basic science research to clinical medicine where she sees patients diagnosed with breast cancer. Additionally, she has an appointment at the Palo Alto VA as a staff oncologist where she focuses on women's cancers and women at high risk of developing breast and gynecologic cancers. She is involved in several translational research projects at the VA, as well as being involved in clinical trials. -
Sean Paul Spencer, MD,PhD
Assistant Professor of Medicine (Gastroenterology and Hepatology)
BioSean Spencer, MD,PhD is a Gastroenterologist and Physician Scientist at Stanford University working to uncover the role of dietary intake on the gut microbiome and mucosal immune system. Sean obtained his medical degree University of Pennsylvania, earning his PhD studying nutritional immunology with Yasmine Belkaid,PhD at the National Institutes of Health (NIH), after which he moved to Boston for residency training at Massachusetts General Hospital and completed his Gastroenterology training at Stanford University. Sean’s career goal is to study mechanisms by which dietary intake influences our microbiome and immune system to better understand and treat gastrointestinal disease. Sean has launched a microbiome-focused clinical practice at Stanford where he is working to develop novel microbiome diagnostics and microbial medicines.
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Victoria "Vicki" Spencer
Adm Assoc 4, Pediatrics - Peds/Critical Care
BioA graduate of Purdue University, Vicki brings over 20 years of executive administrative support experience to her position at Stanford Medicine.
Prior to taking this role, Vicki supported the Chief Medical Officer and Chief Dental Officer for a group of Federally Qualified Health Centers (FQHC). She has also provided executive support to individuals in the field(s) of healthcare, food equity, and pre-clinical drug development.
Her passions are health equity and whole-system integrated care. -
Adam Sperling, MD, PhD
Assistant Professor of Medicine (Hematology)
BioDr. Sperling received his medical degree and PhD in Biological Chemistry from the University of California, Los Angeles in 2011. He completed his residency in internal medicine at the Brigham and Women's Hospital and his fellowship in Hematology and Oncology at the Dana-Farber Cancer Institute. He received board certification from the American Board of Internal Medicine in 2014, in Medical Oncology in 2017 and in Hematology in 2018. He was a member of the staff at the Dana-Farber Cancer Institute and the Brigham and Women's Hospital in Boston from 2018-2026, where he was an Assistant Professor of Medicine at Harvard Medical School. He joined the faculty at Stanford University in 2026, where he is a hematologist and basic and translational researcher in hematologic malignancies. He cares for patients with multiple myeloma and related blood cancers and his research focuses on understanding the mechanisms of disease evolution from pre-malignant conditions and the development of drug resistance in multiple myeloma and other hematologic malignancies.
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David Spiegel
Jack, Lulu and Sam Willson Professor of Medicine
On Partial Leave from 10/01/2025 To 05/15/2026Current Research and Scholarly InterestsDr. Spiegel's research program involves mind/body interactions, including cancer progression, the response to traumatic stress, and the effect of hypnosis on the perception of pain and anxiety.
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Edda Spiekerkoetter
Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsPulmonary Arterial Hypertension
Pulmonary Vascular Remodeling
Modulation of BMPR, ENG, ACVRL1 (ALK1), SMAD signaling
Structural and molecular programs governing right ventricular adaptation and failure
Hereditary Hemorrhagic Telangiectasia
Pulmonary Arteriovenous malformations
Computational Drug Prediction and Repurposing
Deep Tissue Confocal Imaging -
Daniel Spielman
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsMy research interests are in the field of medical imaging, particularly magnetic resonance imaging and in vivo spectroscopy. Current projects include MRI and MRS at high magnetic fields and metabolic imaging using hyperpolarized 13C-labeled MRS.
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Joshua M. Spin
Clinical Associate Professor, Medicine - Cardiovascular Medicine
Current Research and Scholarly InterestsDr. Spin began his research career studying the structural biology of low density lipoprotein, and has had intensive training in molecular biology techniques, particularly high-throughput genetic expression profiling. He is especially interested in vascular smooth muscle cells, and the role of smooth muscle differentiation and phenotypic switching in development, and in vascular disease. His latest work has focused on the biology of aortic aneurysms.
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Chelse Spinner, PhD, MPH
Postdoctoral Scholar, Neonatal and Developmental Medicine
BioAn Ohio native, Dr. Chelse Spinner obtained a Bachelor of Science in Biological Sciences (Biomedical Studies) with a minor in Health Education from the University of Cincinnati. She earned a Master of Public Health in Epidemiology and Maternal & Child Health (MCH) from the University of South Florida. She received a Doctor of Philosophy in Public Health Sciences with a concentration in Behavioral Sciences from the University of North Carolina at Charlotte. Dr. Spinner is certified in public health and has experience working across health systems. Her research interests include health disparities, women’s health, social determinants of health, domains of structural racism, and oral-systemic health within the MCH population. She employs quantitative and qualitative methods in the hopes of providing innovative and evidence-informed research to improve health outcomes for marginalized and underserved communities. Her research agenda intends to focus on the exploration of social and structural factors that impact health and well-being.
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Caleb Matthew Spiro
Casual Non-Exempt, Psychiatry and Behavioral Sciences
BioMy main research interest revolves around understanding the general cognitive and affective properties of the mind, and how the prognosis of good and poor mental health status affects the developmental trajectories under chronic stress. To what extent reward-based networks can lead to increased proximity to vulnerability or heightened sensitivity to mental illness, specifically within the context of youth and adolescents, is an area that I am especially interested in. I am most interested in what factors help individuals become more resilient and build a narrative that they can get better with the right treatment practices. I believe that this can be done by combining neuroscience and functional imaging techniques (ex: fMRI, EEG) into the study and practice of clinical psychology.
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Alfred M. Spormann
Professor of Civil and Environmental Engineering and of Chemical Engineering, Emeritus
Current Research and Scholarly InterestsMetabolism of anaerobic microbes in diseases, bioenergy, and bioremediation
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James Spudich
Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Emeritus
Current Research and Scholarly InterestsThe general research interest of this laboratory is the molecular basis of cell motility, with a current emphasis on power output by the human heart. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement, changes in cell shape and muscle contraction.
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Sandy Srinivas
Professor of Medicine (Oncology) and, by courtesy, of Urology
Current Research and Scholarly InterestsClinical interests: general oncology, genito-urinary malignancy Research interests: conducting clinical trials in advanced prostate cancer, bladder cancer and renal cell carcinoma
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Gayathri Srinivasan OD, MS
Clinical Associate Professor, Ophthalmology
BioDr. Srinivasan is a Clinical Associate Professor in the Department of Ophthalmology at Stanford University. Her clinical focus is on the management of amblyopia, strabismus, childhood refractive errors, and concussion-related vision disorders in children and adults. Dr. Srinivasan's research interests are amblyopia, strabismus, and concussion-related vision disorders. She serves as co-Investigator in ongoing clinical trials through the Pediatric Eye Disease Investigator Group (PEDIG), funded by the NIH, and chairs the Pediatrics and Strabismus subgroup within the Observational Health Data Sciences and Informatics (OHDSI) network.
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Malathi Srinivasan
Clinical Professor, Medicine - Primary Care and Population Health
BioDr. Srinivasan is a Clinical Professor of Medicine at Stanford University, Associate Director at the Stanford Center for Asian Healthcare Research and Education (Stanford CARE), Director of the Stanford CARE Scholars research program, Director of the Stanford Implementation Sciences Fellowship, Fellow at the Stanford Center for Innovation in Global Health (CIGH), Board Member for the Stanford Health Professions Education and Scholars (SHaPES, formerly CTSS), and member of the Stanford Teaching and Mentoring Academy (TMA). She is co-Director of the One Health Teaching Scholars Faculty Development Program, an international program focusing on faculty development for health professions education around the world. She was a regular contributor to CBS-KPIX “Medical Mondays”. Dr. Srinivasan brings her skills as an educator, physician, health services researcher, and entrepreneur to considering how scalable technologies can improve health care. Her work in Virtual Health/telemedicine and new patient engagement models has been published in the NEJM Catalyst – a leading healthcare innovation journal.
Previously, Dr. Srinivasan was a Master Clinical Educator and Professor of Clinical Medicine at the University of California, Davis School of Medicine. She was the Senior Associate Editor and Editorial Fellowship Director for the Journal of General Internal Medicine, and was the Kimitaka Kaga Visiting Professor at the University of Tokyo at the International Research Center for Medical Education. At UC Davis, Dr. Srinivasan was the Director of Practice Based Learning and Improvement and Medical Director of the Clinical Performance Examination for a decade. She is former President of the California-Hawaii Society of General Internal Medicine, and ex-officio National Council Member for SGIM. She was a Robert Wood Johnson Foundation Generalist Physician Faculty Scholar and US Health and Human Service Public Policy Fellow. Dr. Srinivasan has been awarded the California SGIM Educator of the Year Award, Mentor of the Year (California American College of Physicians), and Faculty of the Year (Stanford CARE), and was recognized with the Dean’s Award for Excellence in Education (UC Davis). Her research has focused on two themes. First, addressing health disparities for vulnerable populations, and improving the health of Asians through research & systems change. Second, improving physician competency around clinical decision-making, through Virtual Health, technology-aided education and reflective practice.
Dr. Srinivasan has been working in the Stanford Medical Humanities & the Arts program, as Director of the Medicine, Movement & Dance program, and building patient-facing programs n Medical Humanities She serves on the Executive Board of The Pegasus Physician Writers Program, and enjoys her time as a novice creative writer. -
Suhas Srinivasan, Ph.D.
Principal Bioinformatics Scientist, Dermatology
BioI develop computational algorithms including AI/ML and statistical methods to discover insights at various resolutions of the biological hierarchy i.e., molecules, cells, tissues, organs, organism and population-scale.
In my current role in the laboratories of Paul Khavari and Howard Chang I conduct bioinformatics research to study the molecular mechanisms of tissue development, cancers, autoimmunity and chronic diseases using multiomics, with a focus on the non-coding genome.
I have ten years of academic research experience and received my Ph.D. in Data Science specializing in AI/ML development for diverse topics in biomedicine.
My research interests include artificial intelligence to identify novel patterns in multiomics data, psychometrics and neuroimaging data; structural bioinformatics and computational epidemiology. Additionally, I have conducted research in anomaly detection, and community detection in biological networks.
I am the co-inventor of a patented anomaly detection method for real-time streaming data.
Prior to graduate training and academic research, I was a full-stack software engineer in industry for three years. -
Ankit Srivastava
Temporary Employee, Medicine - Med/Gastroenterology and Hepatology
Current Role at StanfordAs a research scientist, the overarching goal of my research is to elucidate targetable cellular crosstalk between hepatocytes and immune cells in the liver that promotes aging, inflammation, and cancer. To highlight this, I use spatial biology, patient-derived organoids, and disease models of cancer and inflammation.