Showing 1-100 of 943 Results
Assistant Professor of Chemical Engineering and, by courtesy, of Genetics
BioThe Abu-Remaileh Lab is interested in identifying novel pathways that enable cellular and organismal adaptation to metabolic stress and changes in environmental conditions. We also study how these pathways go awry in human diseases such as cancer, neurodegeneration and metabolic syndrome, in order to engineer new therapeutic modalities.
To address these questions, our lab uses a multidisciplinary approach to study the biochemical functions of the lysosome in vitro and in vivo. Lysosomes are membrane-bound compartments that degrade macromolecules and clear damaged organelles to enable cellular adaptation to various metabolic states. Lysosomal function is critical for organismal homeostasis—mutations in genes encoding lysosomal proteins cause severe human disorders known as lysosomal storage diseases, and lysosome dysfunction is implicated in age-associated diseases including cancer, neurodegeneration and metabolic syndrome.
By developing novel tools and harnessing the power of metabolomics, proteomics and functional genomics, our lab will define 1) how the lysosome communicates with other cellular compartments to fulfill the metabolic demands of the cell under various metabolic states, 2) and how its dysfunction leads to rare and common human diseases. Using insights from our research, we will engineer novel therapies to modulate the pathways that govern human disease.
Professor of Medicine (Gastroenterology and Hepatology) at the Stanford University Medical Center
BioMy research interests include nonalcoholic fatty liver disease (NAFLD) and viral hepatitis. I have focused my research to database analysis/outcomes and translational research in these areas. While database analysis has been critical in outlining trends in NAFLD and viral hepatitis epidemiology, translational research has provided insight into disease mechanism and future therapies. I collaborate with several basic science colleagues and act as clinical mentor for young investigators involved in translational research. I am also interested and act as adjunct faculty in biodesign and health policy. I have participated in several clinical trials as a co-investigator.
Alcatel-Lucent Professor in Communications and Networking and Professor of Particle Physics and Astrophysics and of Photon Science
BioAlex Aiken is the Alcatel-Lucent Professor of Computer Science at Stanford. Alex received his Bachelors degree in Computer Science and Music from Bowling Green State University in 1983 and his Ph.D. from Cornell University in 1988. Alex was a Research Staff Member at the IBM Almaden Research Center (1988-1993) and a Professor in the EECS department at UC Berkeley (1993-2003) before joining the Stanford faculty in 2003. His research interest is in areas related to programming languages.
Assistant Professor of Radiology (Neuroimaging) and, by courtesy, of Psychiatry and Behavioral Sciences and of Materials Science and Engineering
Current Research and Scholarly InterestsOur goal is to develop and clinically implement new technologies for high-precision and noninvasive intervention upon the nervous system. Every few millimeters of the brain is functionally distinct, and different parts of the brain may have counteracting responses to therapy. To better match our therapies to neuroscience, we develop techniques that allow intervention upon only the right part of the nervous system at the right time, using technologies like focused ultrasound and nanotechnology.
Ash A. Alizadeh, MD/PhD
Associate Professor of Medicine (Oncology)
Current Research and Scholarly InterestsMy research is focused on attaining a better understanding of the initiation, maintenance, and progression of tumors, and their response to current therapies toward improving future treatment strategies. In this effort, I employ tools from functional genomics, computational biology, molecular genetics, and mouse models.
Clinically, I specialize in the care of patients with lymphomas, working on translating our findings in prospective cancer clinical trials.
Russ B. Altman
Kenneth Fong Professor and Professor of Bioengineering, of Genetics, of Medicine (General Medical Discipline), of Biomedical Data Science and, by courtesy, of Computer ScienceOn Partial Leave from 01/01/2021 To 06/30/2021
Current Research and Scholarly InterestsI refer you to my web page for detailed list of interests, projects and publications. In addition to pressing the link here, you can search "Russ Altman" on http://www.google.com/
Derek F. Amanatullah, M.D., Ph.D.
Assistant Professor of Orthopaedic Surgery at the Stanford University Medical Center
BioDr. Amanatullah specializes in hip and knee replacements for individuals with osteoarthritis, rheumatoid arthritis, infectious arthritis and avascular necrosis. He also performs revision surgeries of knee and hip implants with problems.
Kanwaljeet S. Anand
Professor of Pediatrics (Pediatric Critical Care) and of Anesthesiology, Perioperative and Pain Medicine at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Anand is a translational clinical researcher who pioneered research on the endocrine-metabolic stress responses of infants undergoing surgery and developed the first-ever scientific rationale for pain perception in early life. This provided a framework for newer methods of pain assessment, numerous clinical trials of analgesia/anesthesia in newborns, infants and older children. His research focus over the past 30+ years has contributed fundamental knowledge about pediatric pain/stress, long-term effects of pain in early life, management of pain, mechanisms for opioid tolerance and withdrawal. Current projects in his laboratory are focused on developing biomarkers for repetitive pain/stress in critically ill children and the mechanisms underlying sedative/anesthetic neurotoxicity in the immature brain. He designed and directed many randomized clinical trials (RCT), including the largest-ever pediatric analgesia trial studying morphine therapy in ventilated preterm neonates. He has extensive experience in clinical and translational research from participating in collaborative networks funded by NIMH, NINDS, or NICHD, a track-record of excellent collaboration across multiple disciplines, while achieving success with large research teams like the Collaborative Pediatric Critical Care Research Network (CPCCRN). He played a leadership roles in CANDLE (Condition Affecting Neuro-Development & Learning in Early infancy) and other activities of the Urban Child Institute and UT Neuroscience Institute. More recently, he led the NeoOpioid Consortium funded by the European Commission, which collected data from 243 NICUs in 18 European countries.
Professor of Neurology at the Stanford University Medical Center
Current Research and Scholarly InterestsOur research focuses on understanding how immune responses initiate and accelerate synaptic and neuronal injury in age-related neurodegeneration, including models of Alzheimer's disease and Parkinson's disease. We also focus on the role of immune responses in aggravating brain injury in models of stroke. Our goal is the identification of critical immune pathways that function in neurologic disorders and that can be targeted to elicit disease modifying effects.
Associate Professor of Medicine (Infectious Diseases) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsOur laboratory aims to develop and test innovative approaches to the diagnosis, treatment and control of infectious diseases in resource-limited settings. We draw upon multiple fields including mathematical modeling, microbial genetics, field epidemiology, statistical inference and biodesign to work on challenging problems in infectious diseases, with an emphasis on tuberculosis and tropical diseases.
Thomas P. Andriacchi
Professor of Mechanical Engineering and of Orthopaedic Surgery, Emeritus
Current Research and Scholarly InterestsProfessor Andriacchi's research focuses on the biomechanics of human locomotion and applications to medical devices, sports injury, osteoarthritis, the anterior cruciate ligament and low cost prosthetic limbs
Martin S. Angst
Professor of Anesthesiology, Perioperative and Pain Medicine at the Stanford University Medical Center
Current Research and Scholarly InterestsOur laboratory's current transformative research efforts focus on studying immune health in the context of surgery and anesthesia.
Justin P. Annes M.D., Ph.D.
Associate Professor of Medicine (Endocrinology)
Current Research and Scholarly InterestsThe ANNES LABORATORY of Molecular Endocrinology: Leveraging Chemical Biology to Treat Endocrine Disorders
The prevalence of diabetes is increasing at a staggering rate. By the year 2050 an astounding 25% of Americans will be diabetic. The goal of my research is to uncover therapeutic strategies to stymie the ensuing diabetes epidemic. To achieve this goal we have developed a variety of innovate experimental approaches to uncover novel approaches to curing diabetes.
(1) Beta-Cell Regeneration: Diabetes results from either an absolute or relative deficiency in insulin production. Our therapeutic strategy is to stimulate the regeneration of insulin-producing beta-cells to enhance an individual’s insulin secretion capacity. We have developed a unique high-throughput chemical screening platform which we use to identify small molecules that promote beta-cell growth. This work has led to the identification of key molecular pathways (therapeutic targets) and candidate drugs that promote the growth and regeneration of islet beta-cells. Our goal is to utilize these discoveries to treat and prevent diabetes.
(2) The Metabolic Syndrome: A major cause of the diabetes epidemic is the rise in obesity which leads to a cluster of diabetes- and cardiovascular disease-related metabolic abnormalities that shorten life expectancy. These physiologic aberrations are collectively termed the Metabolic Syndrome (MS). My laboratory has developed an original in vivo screening platform t to identify novel hormones that influence the behaviors (excess caloric consumption, deficient exercise and disrupted sleep-wake cycles) and the metabolic abnormalities caused by obesity. We aim to manipulate these hormone levels to prevent the development and detrimental consequences of the MS.
HEREDIATY PARAGAGLIOMA SYNDROME
The Hereditary Paraganglioma Syndrome (hPGL) is a rare genetic cancer syndrome that is most commonly caused by a defect in mitochondrial metabolism. Our goal is to understand how altered cellular metabolism leads to the development of cancer. Although hPGL is uncommon, it serves as an excellent model for the abnormal metabolic behavior displayed by nearly all cancers. Our goal is to develop novel therapeutic strategies that target the abnormal behavior of cancer cells. In the laboratory we have developed hPGL mouse models and use high throughput chemical screening to identify the therapeutic susceptibilities that result from the abnormal metabolic behavior of cancer cells.
As a physician scientist trained in clinical genetics I have developed expertise in hereditary endocrine disorders and devoted my efforts to treating families affected by the hPGL syndrome. By leveraging our laboratory expertise in the hPGL syndrome, our care for individuals who have inherited the hPGL syndrome is at the forefront of medicine. Our goal is to translate our laboratory discoveries to the treatment of affected families.
Assistant Professor of Material Science and Engineering, by courtesy, of Pediatrics (Endocrinology) and Center Fellow, by courtesy, at the Woods Institute for the Environment
Current Research and Scholarly InterestsThe underlying theme of the Appel Lab at Stanford University integrates concepts and approaches from supramolecular chemistry, natural/synthetic materials, and biology. We aim to develop supramolecular biomaterials that exploit a diverse design toolbox and take advantage of the beautiful synergism between physical properties, aesthetics, and low energy consumption typical of natural systems. Our vision is to use these materials to solve fundamental biological questions and to engineer advanced healthcare solutions.
Associate Professor of Electrical EngineeringOn Partial Leave from 04/01/2021 To 06/30/2021
Current Research and Scholarly InterestsMy group's research covers RF circuits and system design for (1) biomedical, (2) sensing, and (3) Internet of Things (IoT) applications.
Ronald L. Ariagno
Professor (Clinical) of Pediatrics, Emeritus
Current Research and Scholarly InterestsDevelopmental Physiology and Sudden Infant Death Syndrome Research Laboratory closed in 2008.
Current effort, as Chair of Task Force and neonatal consult at the FDA, is to establish through consensus a culture of investigation and collaboration for all clinical neonatology practices: academic, corporate and community based to maximize the opportunity to participate in research effort needed for the regulatory approval of neonatal therapeutics to improve the outcome of critically ill infants.
Donald and Donald M. Steel Professor in Earth Sciences
Current Research and Scholarly InterestsInvestigates role of ocean biology in gobal carbon and nutrient cycles.
Laurie Kraus Lacob Director of the Stanford Cancer Institute (SCI), Jerome and Daisy Low Gilbert Professor and Professor of Biochemistry
Current Research and Scholarly InterestsTelomeres are nucleoprotein complexes that protect chromosome ends and shorten with cell division and aging. We are interested in how telomere shortening influences cancer, stem cell function, aging and human disease. Telomerase is a reverse transcriptase that synthesizes telomere repeats and is expressed in stem cells and in cancer. We have found that telomerase also regulates stem cells and we are pursuing the function of telomerase through diverse genetic and biochemical approaches.
Ann M. Arvin
Lucile Salter Packard Professor of Pediatrics and Professor of Microbiology and ImmunologyOn Partial Leave from 09/01/2019 To 08/31/2021
Current Research and Scholarly InterestsOur laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.
Euan A. Ashley
Associate Dean, School of Medicine, Professor of Medicine (Cardiovascular), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology at the Stanford University Medical Center
Current Research and Scholarly InterestsThe Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.
Professor of Radiation Oncology (Radiation and Cancer Biology) and of Genetics
Current Research and Scholarly InterestsOur research is aimed at defining the pathways of p53-mediated apoptosis and tumor suppression, using a combination of biochemical, cell biological, and mouse genetic approaches. Our strategy is to start by generating hypotheses about p53 mechanisms of action using primary mouse embryo fibroblasts (MEFs), and then to test them using gene targeting technology in the mouse.
Professor of Pathology
Current Research and Scholarly InterestsGenetic and cell biological analyses of signals controlling cell polarity and morphogenesis. Frizzled signaling and cytoskeletal organization.
Dan E. Azagury, MD, FACS
Associate Professor of Surgery (General Surgery) at the Stanford University Medical Center
Current Research and Scholarly Interests.
Associate Professor (Research) of Pediatrics (Stem Cell Transplantation)
Current Research and Scholarly InterestsIn the coming years, I plan to further determine the genetic and immunological basis of diseases with autoimmunity or immune dysregulation in children. I believe that much can still be learned from the in depth mechanistic studies of pediatric autoimmune diseases. Genomic analysis of the patients' samples has become possible which may provide a rapid indication of altered target molecules. I plan to implement robust functional studies to define the consequences of these genetic abnormalities and bridge them to the patient's clinical phenotype.
Understanding functional consequences of gene mutations in single case/family first and then validating the molecular and cellular defects in other patients with similar phenotypes, will anticipate and complement cellular and gene therapy strategies.
For further information please visit the Bacchetta Lab website:
Stephen A. Baccus
Professor of Neurobiology
Current Research and Scholarly InterestsWe study how the neural circuitry of the vertebrate retina encodes visual information and performs computations. To control and measure the retinal circuit, we present visual images while performing simultaneous two-photon imaging and multielectrode recording. We perturb the circuit as it operates using simultaneous intracellular current injection and multielectrode recording, and use the resulting large data sets to construct models of retinal computation.
Thomas More Storke Professor, Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Education
BioJeremy Bailenson is founding director of Stanford University’s Virtual Human Interaction Lab, Thomas More Storke Professor in the Department of Communication, Professor (by courtesy) of Education, Professor (by courtesy) Program in Symbolic Systems, a Senior Fellow at the Woods Institute for the Environment, and a Faculty Leader at Stanford’s Center for Longevity. He earned a B.A. cum laude from the University of Michigan in 1994 and a Ph.D. in cognitive psychology from Northwestern University in 1999. He spent four years at the University of California, Santa Barbara as a Post-Doctoral Fellow and then an Assistant Research Professor.
Bailenson studies the psychology of Virtual and Augmented Reality, in particular how virtual experiences lead to changes in perceptions of self and others. His lab builds and studies systems that allow people to meet in virtual space, and explores the changes in the nature of social interaction. His most recent research focuses on how virtual experiences can transform education, environmental conservation, empathy, and health. He is the recipient of the Dean’s Award for Distinguished Teaching at Stanford.
He has published more than 100 academic papers, in interdisciplinary journals such as Science, the Journal of the American Medical Association, and PLoS One, as well domain-specific journals in the fields of communication, computer science, education, environmental science, law, marketing, medicine, political science, and psychology. His work has been continuously funded by the National Science Foundation for 15 years.
Bailenson consults pro bono on Virtual Reality policy for government agencies including the State Department, the US Senate, Congress, the California Supreme Court, the Federal Communication Committee, the U.S. Army, Navy, and Air Force, the Department of Defense, the Department of Energy, the National Research Council, and the National Institutes of Health.
His first book Infinite Reality, co-authored with Jim Blascovich, was quoted by the U.S. Supreme Court outlining the effects of immersive media. His new book, Experience on Demand, was reviewed by The New York Times, The Wall Street Journal, The Washington Post, Nature, and The Times of London, and was an Amazon Best-seller.
He has written opinion pieces for The Washington Post, CNN, PBS NewsHour, Wired, National Geographic, Slate, The San Francisco Chronicle, and The Chronicle of Higher Education, and has produced or directed five Virtual Reality documentary experiences which were official selections at the Tribeca Film Festival. His lab’s research has exhibited publicly at museums and aquariums, including a permanent installation at the San Jose Tech Museum.
Professor of Genetics
Current Research and Scholarly InterestsWe examine how cells communicate and function during fetal development. The work in my laboratory focuses on the establishment of specific cell fates using genomics to decipher interactions between chromatin and developmental signaling cascades, between genomes and rapidly evolving cell types, and between genomic copy number variation and gene expression. In recent years we have focused on the vastly understudied biology of the trophoblast lineage, particularly how this lineage evolved.
Karthik Balakrishnan, MD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Balakrishnan's research focuses on innovative ways to improve and standardize treatments and measure outcomes in complex pediatric airway and aerodigestive conditions , as well as ways to reduce treatment costs and medical errors. By improving outcomes and reducing costs, he aims to improve the value of care, while also optimizing patient and caregiver experience during the care process.
Richard W. Weiland Professor in the School of Engineering and Professor of Electrical Engineering
BioNick Bambos is a Professor at Stanford University, having a joint appointment in the Department of Electrical Engineering and the Department of Management Science & Engineering. He heads the Network Architecture and Performance Engineering research group at Stanford, conducting research in wireless network architectures, the Internet infrastructure, packet switching, network management and information service engineering, engaged in various projects of his Network Architecture Laboratory (NetLab). His current technology research interests include high-performance networking, autonomic computing, and service engineering. His methodological interests are in network control, online task scheduling, queueing systems and stochastic processing networks.
He has graduated over 20 Ph.D. students, who are now at leadership positions in academia (Stanford, CalTech, Michigan, GaTech, NYU, UBC, etc.) and the information technology industry (Cisco, Broadcom, IBM Labs, Qualcomm, Nokia, MITRE, Sun Labs, ST Micro, Intel, Samsung, TI, etc.) or have become successful entrepreneurs. From 1999 to 2005 he served as the director of the Stanford Networking Research Center, a major partnership/consortium between Stanford and information technology industries, involving tens of corporate members, faculty and doctoral students. He is now heading a new research initiative at Stanford on Networked Information Service Engineering.
He is on the Editorial Boards of several research journals and serves on various international technical committees and review panels for networking research and information technologies. He has been serving on the boards of various start-up companies in the Silicon Valley, consults on high technology development and management matters, and has served as lead expert witness in high-profile patent litigation cases in networking and computing.
Professor of Pathology and of Medicine (Infectious Diseases) at the Stanford University Medical Center
Current Research and Scholarly InterestsHis research interests include (1) development, assessment, and improvement of novel infectious diseases diagnostics, (2) enhancing the quality of C. difficile diagnostic results, and (3) characterization of M. tuberculosis virulence determinants.
K. K. Lee Professor in the School of Engineering, Senior Fellow at the Precourt Institute for Energy and Professor, by courtesy, of Materials Science and Engineering and of Chemistry
BioZhenan Bao joined Stanford University in 2004. She is currently a K.K. Lee Professor in Chemical Engineering, and with courtesy appointments in Chemistry and Material Science and Engineering. She is the Department Chair of Chemical Engineering from 2018. She is a member of the National Academy of Engineering and National Academy of Inventors. She founded the Stanford Wearable Electronics Initiative (eWEAR) and is the current faculty director. She is also an affiliated faculty member of Precourt Institute, Woods Institute, ChEM-H and Bio-X. Professor Bao received her Ph.D. degree in Chemistry from The University of Chicago in 1995 and joined the Materials Research Department of Bell Labs, Lucent Technologies. She became a Distinguished Member of Technical Staff in 2001. Professor Bao currently has more than 550 refereed publications and more than 65 US patents. She served as a member of Executive Board of Directors for the Materials Research Society and Executive Committee Member for the Polymer Materials Science and Engineering division of the American Chemical Society. She was an Associate Editor for the Royal Society of Chemistry journal Chemical Science, Polymer Reviews and Synthetic Metals. She serves on the international advisory board for Advanced Materials, Advanced Energy Materials, ACS Nano, Accounts of Chemical Reviews, Advanced Functional Materials, Chemistry of Materials, Chemical Communications, Journal of American Chemical Society, Nature Asian Materials, Materials Horizon and Materials Today. She is one of the Founders and currently sits on the Board of Directors of C3 Nano Co. and PyrAmes, both are silicon valley venture funded companies. She is Fellow of AAAS, ACS, MRS, SPIE, ACS POLY and ACS PMSE. She was a recipient of the ACS Central Science Disruptor and Innovator Prize in 2020, ACS Gibbs Medal in 2020, the Wilhelm Exner Medal from the Austrian Federal Minister of Science in 2018, the L'Oreal UNESCO Women in Science Award North America Laureate in 2017. She was awarded the ACS Applied Polymer Science Award in 2017, ACS Creative Polymer Chemistry Award in 2013 ACS Cope Scholar Award in 2011, and was selected by Phoenix TV, China as 2010 Most influential Chinese in the World-Science and Technology Category. She is a recipient of the Royal Society of Chemistry Beilby Medal and Prize in 2009, IUPAC Creativity in Applied Polymer Science Prize in 2008, American Chemical Society Team Innovation Award 2001, R&D 100 Award, and R&D Magazine Editors Choice Best of the Best new technology for 2001. She has been selected in 2002 by the American Chemical Society Women Chemists Committee as one of the twelve Outstanding Young Woman Scientist who is expected to make a substantial impact in chemistry during this century. She is also selected by MIT Technology Review magazine in 2003 as one of the top 100 young innovators for this century. She has been selected as one of the recipients of Stanford Terman Fellow and has been appointed as the Robert Noyce Faculty Scholar, Finmeccanica Faculty Scholar and David Filo and Jerry Yang Faculty Scholar.
Associate Professor of Genetics
Current Research and Scholarly InterestsOur lab studies how intricate control of gene expression and cell signaling is regulated on a minute-by-minute basis to give rise to the remarkable diversity of cell types and tissue morphology that form the living blueprints of developing organisms. Work in the Barna lab is presently split into two main research efforts. The first is investigating ribosome-mediated control of gene expression genome-wide in space and time during cellular differentiation and organismal development. This research is opening a new field of study in which we apply sophisticated mass spectrometry, computational biology, genomics, and developmental genetics, to characterize a ribosome code to gene expression. Our research has shown that not all of the millions of ribosomes within a cell are the same and that ribosome heterogeneity can diversify how genomes are translated into proteomes. In particular, we seek to address whether fundamental aspects of gene regulation are controlled by ribosomes harboring a unique activity or composition that are tuned to translating specific transcripts by virtue of RNA regulatory elements embedded within their 5’UTRs. The second research effort is centered on employing state-of-the-art live cell imaging to visualize cell signaling and cellular control of organogenesis. This research has led to the realization of a novel means of cell-cell communication dependent on a dense network of actin-based cellular extension within developing organs that interconnect and facilitate the precise transmission of molecular information between cells. We apply and create bioengineering tools to manipulate such cellular interactions and signaling in-vivo.
Annelise E. Barron
Associate Professor of Bioengineering
Current Research and Scholarly InterestsBiophysical mechanisms of host defense peptides (a.k.a. antimicrobial peptides) and their peptoid mimics; also, molecular and cellular biophysics of human innate immune responses.
Professor of Genetics and of Pediatrics, Emeritus
Current Research and Scholarly InterestsGenetics of color variation
Associate Professor of Genetics
Current Research and Scholarly InterestsMy laboratory is focused on (1) the development of new technologies for high-throughput functional genomics using the CRISPR/Cas9 system, and (2) application of these tools to study the cellular response to drugs and endocytic pathogens (such as bacteria, viruses, and protein toxins). Fascinating in themselves, these pathogens also help illuminate basic cell biology. A complementary interest is in the identification of new drug targets and combinations to combat cancer and neurodegeneration.
Associate Professor of Operations, Information and Technology at the Graduate School of Business and, by courtesy, of Electrical EngineeringOn Leave from 03/15/2021 To 12/31/2021
Current Research and Scholarly Interests1) Healthcare management: I am interested in improving healthcare delivery using data-driven modeling and decision-making.
2) Network models and message-passing algorithms: I work on graphical modeling ideas motivated from statistical physics and their applications in statistical inference.
3) Personalized decision-making: I work on machine learning and statistical challenges of personalized decision-making. The problems that I have worked on are primarily motivated by healthcare applications.
The Ernest and Amelia Gallo Professor in the School of Medicine, Professor of Urology, of Developmental Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsFunction of Hedgehog proteins and other extracellular signals in morphogenesis (pattern formation), in injury repair and regeneration (pattern maintenance). We study how the distribution of such signals is regulated in tissues, how cells perceive and respond to distinct concentrations of signals, and how such signaling pathways arose in evolution. We also study the normal roles of such signals in stem-cell physiology and their abnormal roles in the formation and expansion of cancer stem cells.
Christopher Beaulieu M.D., Ph.D.
Professor of Radiology (Musculoskeletal Imaging) and, by courtesy, of Orthopaedic Surgery at the Stanford University Medical Center
Current Research and Scholarly InterestsInformatics and image processing techniques that provide infrastructure for diagnosis in musculoskeletal imaging. Decision support for improving accuracy of bone tumor diagnosis. Improved methods for MRI in the musculoskeletal system.
Barry Behr, Ph.D., H.C.L.D.
Professor of Obstetrics and Gynecology (Reproductive Endocrinology and Infertility) at the Stanford University Medical CenterOn Leave from 03/29/2021 To 05/31/2021
Current Research and Scholarly InterestsDevelopment of improved embryo culture conditions in vitro. Blastocyst cultures. Embryo metabolism in vitro. Embryo maternal dialogue. Clinical application and integration of extended embryo culture systems. Monozygotic twinning. Prevention of multiple pregnancy. Sperm motility enhancers. Fluorescent and non-fluorescent markers of sperm morphology and viablility. Oocyte cryopreservation. Fertility preservation. Improving IVF outcome.
Professor of Developmental Biology, of Computer Science, of Pediatrics (Genetics) and of Biomedical Data Science
Current Research and Scholarly InterestsDr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species. He is deeply interested in mapping both coding and non-coding genome sequence variation to phenotype differences, and in extracting specific genetic insights from high throughput sequencing measurements, in the contexts of development and developmental abnormalities.
Assistant Professor (Research) of Pathology
Current Research and Scholarly InterestsOur goal is to understand the mechanisms regulating the development of human systems. Drawing on both pluripotent stem cell biology, hematopoiesis, and immunology, combined with novel high-content single-cell analysis (CyTOF – Mass Cytometry) and imagining (MIBI-Multiplexed Ion Beam Imaging) we are creating templates of ‘normal’ human cellular behavior to both discover novel regulatory events and cell populations as well as understand dysfunctional processes such as cancer.
Associate Professor of Medicine (Primary Care and Population Health) and Senior Fellow at the Woods Institute for the EnvironmentOn Partial Leave from 09/14/2020 To 07/05/2021
Current Research and Scholarly InterestsEffect of global health policies on health of individuals in developing countries, global health, HIV and TB.
Vice Provost for Graduate Education and Postdoctoral Affairs, Jagdeep and Roshni Singh Professor in the School of Engineering, and Professor, by courtesy, of Materials Science & Engineering, of Electrical Engineering and of Chemistry
BioThe research in the Bent laboratory is focused on understanding and controlling surface and interfacial chemistry and applying this knowledge to a range of problems in semiconductor processing, micro- and nano-electronics, nanotechnology, and sustainable and renewable energy. Much of the research aims to develop a molecular-level understanding in these systems, and hence the group uses of a variety of molecular probes. Systems currently under study in the group include functionalization of semiconductor surfaces, mechanisms and control of atomic layer deposition, molecular layer deposition, nanoscale materials for light absorption, interface engineering in photovoltaics, catalyst and electrocatalyst deposition.
Jonathan S. Berek, MD, MMS
Laurie Kraus Lacob ProfessorOn Partial Leave from 06/01/2020 To 05/31/2021
BioLaurie Kraus Lacob Professor
Stanford University School of Medicine
Director, Stanford Women’s Cancer Center
Senior Advisor, Stanford Cancer Institute
Director, Stanford Health Communication Initiative
Advancing Communication Excellence at Stanford
Stanford Center for Health Education
Office of the Vice Provost for Teaching and Learning
Director, Stanford Health Care Communication Program
Stanford Health Care
Denning Family Provostial Professor
BioJonathan Berger is the Denning Family Provostial Professor in Music at Stanford University, where he teaches composition, music theory, and cognition at the Center for Computer Research in Music and Acoustics (CCRMA).
Jonathan is a 2017 Guggenheim Fellow and a 2016 winner of the Rome Prize.
He was the founding co-director of the Stanford Institute for Creativity and the Arts (SICA, now the Stanford Arts Institute) and founding director of Yale University’s Center for Studies in Music Technology
Described as “gripping” by both the New York Times and the Chicago Tribune, “poignant”, “richly evocative” (San Francisco Chronicle), “taut, and hauntingly beautiful” (NY Times), Jonathan Berger’s recent works deal with both consciousness and conscience. The Kronos Quartet toured recent monodrama, My Lai internationally. Thrice commissioned by The National Endowment for the Arts, Berger’a recent commissions include The Mellon and Rockefeller Foundations, Chamber Music Society, Lincoln Center, and Chamber Music America. Upcoming commissions include an oratorio entitled The Ritual of Breath, and Leonardo, for baritone and chamber orchestra.
In addition to composition, Berger is an active researcher with over 80 publications in a wide range of fields relating to music, science and technology and has held research grants from DARPA, the Wallenberg Foundation, The National Academy of Sciences, the Keck Foundation, and others.
Shirley R. and Leonard W. Ely, Jr. Professor of the School of Humanities and SciencesOn Leave from 01/01/2021 To 06/30/2021
Current Research and Scholarly InterestsWe use genetic, genomic and cell biological approaches to study cell fate acquisition, focusing on cases where cell fate is correlated with asymmetric cell division.
Assistant Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)On Leave from 04/01/2021 To 09/10/2021
BioDr. Bernert is Founding Director of the Suicide Prevention Research Laboratory, and Co-Chairs a special departmental initiative to develop a Center for Premature Mortality and Suicide Prevention. She is a suicidologist, with subspecialty expertise in suicide prevention clinical trials, standardized suicide risk assessment and best practice management, and the epidemiology of self-directed violence. She has subspecialty training in behavioral sleep medicine, with a background in sleep and circadian physiology. Her program utilizes cognitive, biologic (e.g., fMRI), and behavioral testing paradigms, with an emphasis on translational therapeutics. Dr. Bernert has collaborated with NIH, DOD, DARPA, SAMHSA, and CDC on suicide prevention initiatives; and recently served as a content expert for the White House 2015 Open Data and Innovation for Suicide Prevention #Hackathon. She has also contributed to the development of clinical practice parameters, including the 2013 VA/DOD Clinical Practice Guidelines for the Assessment and Management of Suicide Risk, with current work underway focused on investigating medical education training in suicide risk assessment and management. Her research focuses on the identification of novel therapeutic targets for suicide prevention across the lifespan, particularly those aiming to reduce stigma and enhance access to care. A specific focus of this work emphasizes the use of rapid-action, low-risk treatment approaches for the prevention of suicide. Dr. Bernert has several suicide prevention trials underway, funded by NIH and DOD, testing the preliminary efficacy of a non pharmacological insomnia treatment on suicidal behaviors. She also has several grants focused on the development of a data monitoring system for the study of local suicide clusters and emergency department based protocols to improve risk detection within pediatric suicide prevention. Our aim is to delineate transdiagnostic risk factors and biomarkers of clinical response that may inform the pathogenesis of risk and treatment innovation. An overarching mission is to harness new technologies within suicide prevention, including artificial intelligence (AI) and mobile health applications, to enhance risk detection and multidisciplinary frameworks. Advisory and advocacy work, and the way in which research guides health policy, dissemination, and national strategies for suicide prevention, represents an extension of this work. This includes recent initiatives to establish national and local guidelines for lethal means restriction and calls for advanced technology use in suicide prevention research and strategy. Last, Dr. Bernert has several pilot projects underway focused on inclusive practices in faculty diversity and development, and the way in which family-friendly policies impact faculty recruitment and retention in academic medicine.
Alfred Woodley Salter and Mabel Smith Salter Endowed Professor in Pediatrics
Current Research and Scholarly Interests1. Using iPSC-derived cardiomyocytes to understand hypertrophic cardiomyopathy and heart failure associated with congenital heart disease.
2. Role of alterations in mitochondrial dycamics and function in normal physiology and disease.
3. Differences between R and L ventricular responses to stress,
4. Immune biomarkers of risk after pediatric VAD implantation.
5. Biomarkers for post-transplant lymphoproliferative disorder.
Professor of Pediatrics (Genetics) at the Lucile Salter Packard Children's Hospital and, by courtesy, of Genetics
Current Research and Scholarly InterestsMy research is focused on the diagnosis, discovery and delineation of rare genetic conditions with a focus of neurodevelopmental disorders. This work includes the application of novel computational methods and multi-omics profiling (whole genome sequencing, RNA sequencing, metabolomics). I additionally participate in an interdisciplinary project to develop induced pluripotent stem cell (iPSC) models of genetic neurodevelopmental disorders..
Associate Professor of Computer Science
BioMichael Bernstein is an Associate Professor of Computer Science and STMicroelectronics Faculty Scholar at Stanford University, where he is a member of the Human-Computer Interaction group. His research focuses on the design of social computing and crowdsourcing systems. Michael has received eight best paper awards at premier computing venues, and he has been recognized with an NSF CAREER award and an Alfred P. Sloan Fellowship. His Ph.D. students have gone on both to industry (e.g., Adobe Research, Facebook Data Science, entrepreneurship) and faculty careers (e.g., Carnegie Mellon, UC Berkeley). Michael holds a bachelor's degree in Symbolic Systems from Stanford University, as well as a master's degree and a Ph.D. in Computer Science from MIT.
Professor of Pediatrics (Gastroenterology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly InterestsGastroenterology, gastointestinal motility, clinical management of pediatric liver transplant recipients.
Mark Berry, MD
Mylavarapu Rogers Professor of Cardiothoracic Surgery
BioDr. Berry joined the Division of Thoracic Surgery at Stanford in August 2014. He came to Stanford from Duke University, where he had most recently served as Associate Professor. He received his medical degree at the University of Pennsylvania School of Medicine after receiving bachelors and masters degrees in Electrical Engineering at the University of Pennsylvania. He completed his residency in Cardiothoracic Surgery at Duke University Medical Center after performing a residency in General Surgery at the Hospital of the University of Pennsylvania. His Cardiothoracic Surgical training included a year dedicated to Minimally Invasive General Thoracic Surgery, a period that also included an American Association for Thoracic Surgery sponsored Traveling Fellowship at the University of Pittsburgh.
Dr. Berry practices all aspects of thoracic surgery, including procedures for benign and malignant conditions of the lung, esophagus, and mediastinum. He has a particular interest in minimally invasive techniques, and has extensive experience in treating thoracic surgical conditions using video-assisted thoracoscopic surgical (VATS), laparoscopic, robotic, endoscopic, and bronchoscopic approaches. He serves as the co-Director of the Stanford Minimally Invasive Thoracic Surgery Center (SMITS), and has both directed and taught in several minimally invasive thoracic surgery courses.
Dr. Berry also has a Masters of Health Sciences in Clinical Research from Duke University. His clinical research activities mirror his clinical interests and activities in optimizing short-term and long-term outcomes of patients with thoracic surgical conditions. He has more than sixty peer-reviewed publications, most of which are related to both the use of minimally invasive thoracic surgical techniques as well as evaluating outcomes after treatment of thoracic malignancies. His clinical practice and his research both focus on choosing the most appropriate treatment and approach for patients based on the individual characteristics of the patient and their disease process.
Professor of Anesthesiology, Perioperative and Pain Medicine at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly Interestsmolecular modeling of anesthetic-protein interactions, molecular modeling of the ligand-gated ion channels
Alice Bertaina MD, PhD
Associate Professor of Pediatrics (Stem Cell Transplantation) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly InterestsDr. Bertaina is a highly experienced clinician and will play a key role in supporting Section Chief Dr. Rajni Agarwal and Clinical Staff in the Stem Cell Transplant Unit at Lucile Packard Children’s Hospital. She will also continue her research on immune recovery and miRNA, understanding the mechanisms underlying immune reconstitution, Graft-versus-Host Disease (GvHD), and leukemia relapse after allogeneic HSCT in pediatric patients affected by hematological malignant and non-malignant disorders.
Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology
BioProfessor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.
Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosaccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford University in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering & Medicine for Human Health). She is now the Baker Family Director of Stanford ChEM-H.
Named a MacArthur Fellow in 1999, Dr. Bertozzi has received many awards for her dedication to chemistry, and to training a new generation of scientists fluent in both chemistry and biology. She has been elected to the Institute of Medicine, National Academy of Sciences, and American Academy of Arts and Sciences; and received the Lemelson-MIT Prize, the Heinrich Wieland Prize, the ACS Award in Pure Chemistry, and the Chemistry of the Future Solvay Prize, among others.
The Bertozzi Group develops chemical tools to study the glycobiology underlying diseases such as cancer, inflammation, tuberculosis and most recently COVID-19. She is the inventor of "bioorthogonal chemistry", a class of chemical reactions compatible with living systems that enable molecular imaging and drug targeting. Her group also developed new therapeutic modalities for targeted degradation of extracellular biomolecules, such as antibody-enzyme conjugates and Lysosome Targeting Chimeras (LYTACs). As well, her group studies NGly1 deficiency, a rare genetic disease characterized by loss of the human N-glycanase.
Several of the technologies developed in the Bertozzi lab have been adapted for commercial use. Actively engaged with several biotechnology start-ups, Dr. Bertozzi cofounded Redwood Bioscience, Enable Biosciences, Palleon Pharmaceuticals, InterVenn Bio, OliLux Bio, Grace Science LLC and Lycia Therapeutics. She is also a member of the Board of Directors of Lilly.
Vivek Bhalla, MD
Associate Professor of Medicine (Nephrology) at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Bhalla's two primary research interests are in the role of the kidney in diabetes and hypertension. We use molecular, biochemical, and transgenic approaches to study: (1) mechanisms diabetic kidney disease disease including the role of the endothelium to regulate inflammation and kidney injury; and (2) regulation of tubular transport of glucose, sodium, and potassium. These latter studies have treatment implications in diabetes, kidney disease, and hypertension.
Associate Professor of Medicine (Hematology) and of Genetics
Current Research and Scholarly InterestsThe Bhatt lab is exploring how the microbiota is intertwined with states of health and disease. We apply the most modern genetic tools in an effort to deconvolute the mechanism of human diseases.
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsThe long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease.
Assistant Professor of Bioengineering
BioLacra Bintu is an Assistant Professor in the Bioengineering Department at Stanford. Her lab performs single-cell measurements of chromatin and gene regulation dynamics, and uses these data to develop predictive models of basic biological processes and improve mammalian cell engineering.
Lacra started working on the theory of gene regulation as an undergraduate with Jané Kondev from Brandeis University and Rob Phillips from Caltech. As a Physics PhD student in the lab of Carlos Bustamante at U.C. Berkeley, she used single-molecule methods to tease apart the molecular mechanisms of transcription through nucleosomes. She transitioned to studying the dynamics of epigenetic regulation in live cells during her postdoctoral fellowship with Michael Elowitz at Caltech. She started her own interdisciplinary lab at Stanford in January 2017.
Julius Bishop, MD
Associate Professor of Orthopaedic Surgery at the Stanford University Medical Center
Current Research and Scholarly InterestsDr. Bishop specializes in treating fractures of the upper extremity, lower extremity, pelvis and acetabulum as well as the management of post-traumatic problems including malunion, nonunion and infection.
He received his undergraduate and medical school degrees from Harvard University and went on to complete the Harvard Combined Orthopaedic Surgery Residency Program. He pursued his subspecialty training in Orthopaedic Traumatology at the world-renowned Harborview Medical Center in Seattle, Washington.
His research interests include applying decision analysis models to orthopaedic trauma problems, studying clinical outcomes after musculoskeletal injury, orthopaedic biomechanics, the basic science of fracture healing, and evaluating new strategies and techniques in fracture surgery.
Sandip Biswal, MD
Associate Professor of Radiology (Musculoskeletal Imaging) at the Stanford University Medical Center
Current Research and Scholarly InterestsThe management of individuals suffering from chronic pain is unfortunately limited by poor diagnostic tests and therapies. Our research group is interested in 'imaging pain' by using novel imaging techniques to study peripheral nociception and inflammation with the goal of accurately identifying the location of pain generators. We are developing new approaches with positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) and are currently in clinical trials.
Helen M. Blau
The Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral SciencesOn Partial Leave from 01/01/2021 To 12/31/2021
Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
Nikolas Blevins, MD
Larry and Sharon Malcolmson Professor in the School of Medicine and Professor, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsInner ear microendoscopy -- Developing techniques for minimally-invasive imaging of inner ear microanatomy and neural pysiology. Applications include improved cochlear implant development, inner ear regenerative techniques, inner ear surgery, and auditory physiology.
Microsurgical robotics -- Developing scalable microsurgical instrumentation and robotic techniques for use in head and neck surgery.
Surgical Simulation -- Immersive environment for temporal bone surgical simulation.
Professor of Medicine (Infectious Diseases)
Current Research and Scholarly InterestsThe major goal of our research is to gain insight into the prevention and control of HIV and other viral pathogens by studying the interplay between the virus and the host immune response. We investigate the role of various arms of the immune response, but with a particular focus on NK cells. We hope to gain additional insights into control of infectious diseases by studying how pregnancy modulates immune responses.
Steven M. Block
The Stanford W. Ascherman, M.D., Professor and Professor of Applied Physics and of BiologyOn Leave from 09/01/2020 To 08/31/2021
Current Research and Scholarly InterestsSingle molecule biophysics using optical trapping and fluorescence
Mark S. Blumenkranz, MD, MMS
H. J. Smead Professor of Ophthalmology, Emeritus
Current Research and Scholarly InterestsClinical Interest and Research
My primary areas of interest are in the diagnosis, medical and surgical treatment of vitreal retinal diseases. These principally include age-related macular degeneration and other diseases of the macula, and tractional syndromes, diabetic retinopathy, and complex forms of retinal detachment. I have been interested in the development of novel technology to diagnose and treat these diseases, including new forms of imaging, laser delivery systems, other microsurgical tools, and new drugs and drug delivery systems that inhibit new blood vessel growth, scarring and intraocular inflammation. I have been actively involved in translational research in the laboratory as well as technology transfer associated with that research for a variety of new therapies that have received FDA clearance and been introduced into clinical practice over the past 30 years.
Administrative and Community Service
I have served on the Board of Directors of a variety of voluntary education and service organizations, including the Corporation of Brown University, multiple scientific advisory boards and various philanthropic and research organizations.
Professor of Bioengineering, of Electrical Engineering and, by courtesy, of Computer Science
Current Research and Scholarly InterestsLarge-scale models of sensory, perceptual and motor systems
Professor of Civil and Environmental Engineering and Senior Fellow at the Woods Institute for the Environment
BioI am interested in pathogens in the environment including their sources, fate, and transport in natural and engineered systems. I am interested in understanding of how pathogens are transmitted to humans through contact with water, feces, and contaminated surfaces. My research is focused on key problems in both developed and developing countries with the overarching goal of designing and testing novel interventions and technologies for reducing the burden of disease.
I am also interested broadly in coastal water quality where my work addresses the sources, transformation, transport, and ecology of biocolloids - specifically fecal indicator organisms, DNA, pathogens, and phytoplankton - as well as sources and fate of nitrogen. This knowledge is crucial to formulating new management policies and engineering practices that protect human and ecosystem health at the coastal margins.
Assistant Professor of Developmental Biology
Current Research and Scholarly InterestsMy lab focuses on investigating the role of three-dimensional genome organization in regulating gene expression and in shaping cell fate specification during development. We pursue this with advanced single-molecule imaging and transgenics.
Bing Director in Human Biology, Emerita
Current Research and Scholarly InterestsI am interested in how environmental variation affects life history traits, population structure and dynamics, and species interactions in ecological and evolutionary time, using Lepidoptera.
Professor of Pathology and of Microbiology and Immunology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur lab uses chemical, biochemical, and cell biological methods to study protease function in human disease. Projects include:
1) Design and synthesis of novel chemical probes for serine and cysteine hydrolases.
2) Understanding the role of hydrolases in bacterial pathogenesis and the human parasites, Plasmodium falciparum and Toxoplasma gondii.
3) Defining the specific functional roles of proteases during the process of tumorogenesis.
4) In vivo imaging of protease activity
Clinical Instructor, Psychiatry and Behavioral Sciences - Child and Adolescent Psychiatry
Current Research and Scholarly InterestsMy research interests have focused on the neural bases of eating disorders. I am particularly interested in the way emotion and reward is processed in the brain and how that may contribute to eating behavior and food restriction. I hope to eventually translate biological research findings into treatments.
Associate Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsThe Bollyky Lab studies the immunology of chronic bacterial infections with an emphasis on Pseudomonas aeruginosa wound and lung infections in Diabetes and Cystic Fibrosis. Areas of particular interest include bacteriophages, biofilms, and host-pathogen interactions. Our goals are to gain insight into fundamental disease mechanisms and to generate novel therapies to improve human health.
C. Andrew Bonham
Associate Professor of Surgery (Abdominal Transplantation) at the Stanford University Medical Center
Current Research and Scholarly InterestsTolerance induction in liver transplantation.
Burt and Marion Avery Professor of ImmunologyOn Leave from 09/01/2020 To 08/31/2021
Current Research and Scholarly InterestsWe are intereseted in the interaction between the protozoan parasite Toxoplasma gondii and its mammalian host. We use a combination of molecular and genetic tools to understand how this obligate intracellular parasite can invade almost any cell it encounters, how it co-opts a host cell once inside and how it evades the immune response to produce a life-long, persistent infection.
Charles E. Ducommun Professor in the Graduate School of Education
Current Research and Scholarly InterestsToward a Scalable Model of Mathematics Professional Development: A Field Study of Preparing Facilitators to Implement the Problem-Solving Cycle
The Problem-Solving Cycle (PSC) model of mathematics professional development encourages teachers to become part of a collaborative and supportive learning community. As they participate in the PSC, teachers think deeply about both mathematics content and instruction, and they explore their instructional practices with their colleagues through the use of video and other classroom artifacts. One iteration of the PSC consists of three interconnected professional development workshops, all organized around a rich mathematical task. During Workshop 1, teachers collaboratively solve the mathematical task and develop plans for teaching it to their own students. Shortly after the workshop, the teachers implement the problem with their own students and their lessons are videotaped. In Workshop 2 teachers explore the role they played in implementing the problem. In Workshop 3 teachers critically examine students’ mathematical reasoning.
The Problem-Solving Cycle model provides a structure for mathematics teachers to work together and share a common mathematical and pedagogical experience. Our previous research suggests that it is a promising model for enhancing teachers’ knowledge and supporting changes in classroom practice.
In our current project, initiated in Fall 2007, we are working with a group of middle school mathematics teachers in a large urban district to foster their leadership capacity, and specifically to prepare them to facilitate the Problem-Solving Cycle. We will provide 2½ years of preparation and support for teachers who have been designated as “mathematics instructional leaders.” These instructional leaders will in turn implement the PSC with the mathematics teachers in their schools. We will document the range and quality of the instructional leaders’ implementation of the PSC. We will also analyze the impact of the professional development process on the mathematical knowledge and classroom teaching of the instructional leaders and the mathematics teachers with whom they work. In addition, we will analyze the impact on their students’ mathematics achievement. By the conclusion of the project, we anticipate that the participating schools will have the infrastructure and capacity to carry out the PSC indefinitely, using their own resources. In addition, the project will produce a highly refined set of PSC facilitation materials—with a strong emphasis on supporting a linguistically and culturally diverse student population—that can be widely disseminated.
Linda Boxer, MD, PhD
Vice Dean of the School of Medicine and Stanley McCormick Memorial Professor in the School of Medicine
Current Research and Scholarly InterestsRegulation of expression of oncogenes in normal and malignant hematologic cells.
Camille Dreyfus Professor of Chemistry
Current Research and Scholarly InterestsPlease visit my website for complete information:
Professor of Geological Sciences
Current Research and Scholarly InterestsPaleontology/Geobiology; Fossil record of plant physiology and development; Evolution of terrestrial ecosystems including fungi, animals, and environmental feedbacks with the biota
Scott D. Boyd, MD PhD
Associate Professor of Pathology
Current Research and Scholarly InterestsOur goal is to understand the lymphocyte genotype-phenotype relationships in healthy human immunity and in immunological diseases. We apply new technologies and data analysis approaches to this challenge, particularly high-throughput DNA sequencing and single-cell monoclonal antibody generation, in parallel with other functional assays.
Samsung Professor in the School of Engineering and Professor, by courtesy, of Computer Science and of Management Science and Engineering
BioStephen P. Boyd is the Samsung Professor of Engineering, and Professor of Electrical Engineering in the Information Systems Laboratory at Stanford University. He has courtesy appointments in the Department of Management Science and Engineering and the Department of Computer Science, and is member of the Institute for Computational and Mathematical Engineering. His current research focus is on convex optimization applications in control, signal processing, machine learning, and finance.
Professor Boyd received an AB degree in Mathematics, summa cum laude, from Harvard University in 1980, and a PhD in EECS from U. C. Berkeley in 1985. In 1985 he joined Stanford's Electrical Engineering Department. He has held visiting Professor positions at Katholieke University (Leuven), McGill University (Montreal), Ecole Polytechnique Federale (Lausanne), Tsinghua University (Beijing), Universite Paul Sabatier (Toulouse), Royal Institute of Technology (Stockholm), Kyoto University, Harbin Institute of Technology, NYU, MIT, UC Berkeley, CUHK-Shenzhen, and IMT Lucca. He holds honorary doctorates from Royal Institute of Technology (KTH), Stockholm, and Catholic University of Louvain (UCL).
Professor Boyd is the author of many research articles and four books: Introduction to Applied Linear Algebra: Vectors, Matrices, and Least-Squares (with Lieven Vandenberghe, 2018), Convex Optimization (with Lieven Vandenberghe, 2004), Linear Matrix Inequalities in System and Control Theory (with El Ghaoui, Feron, and Balakrishnan, 1994), and Linear Controller Design: Limits of Performance (with Craig Barratt, 1991). His group has produced many open source tools, including CVX (with Michael Grant), CVXPY (with Steven Diamond) and Convex.jl (with Madeleine Udell and others), widely used parser-solvers for convex optimization.
Professor Boyd has received many awards and honors for his research in control systems engineering and optimization, including an ONR Young Investigator Award, a Presidential Young Investigator Award, and the AACC Donald P. Eckman Award. In 2013, he received the IEEE Control Systems Award, given for outstanding contributions to control systems engineering, science, or technology. In 2012, Michael Grant and he were given the Mathematical Optimization Society's Beale-Orchard-Hays Award, for excellence in computational mathematical programming. He is a Fellow of the IEEE, SIAM, and INFORMS, a Distinguished Lecturer of the IEEE Control Systems Society, a member of the US National Academy of Engineering, a foreign member of the Chinese Academy of Engineering, and a foreign member of the National Academy of Engineering of Korea. He has been invited to deliver more than 90 plenary and keynote lectures at major conferences in control, optimization, signal processing, and machine learning.
He has developed and taught many undergraduate and graduate courses, including Signals & Systems, Linear Dynamical Systems, Convex Optimization, and a recent undergraduate course on Matrix Methods. His graduate convex optimization course attracts around 300 students from more than 20 departments. In 1991 he received an ASSU Graduate Teaching Award, and in 1994 he received the Perrin Award for Outstanding Undergraduate Teaching in the School of Engineering. In 2003, he received the AACC Ragazzini Education award, for contributions to control education, with citation: “For excellence in classroom teaching, textbook and monograph preparation, and undergraduate and graduate mentoring of students in the area of systems, control, and optimization.” In 2016 he received the Walter J. Gores award, the highest award for teaching at Stanford University. In 2017 he received the IEEE James H. Mulligan, Jr. Education Medal, for a career of outstanding contributions to education in the fields of interest of IEEE, with citation "For inspirational education of students and researchers in the theory and application of optimization."
Associate Professor of Biochemistry
Current Research and Scholarly InterestsThe Brandman Lab studies how cells sense and respond to stress. We employ an integrated set of techniques including single cell analysis, mathematical modeling, genomics, structural studies, and in vitro assays.
Stephen Harris Professor and Professor of Materials Science and Engineering and, by courtesy, of Applied Physics
BioMark Brongersma is a Professor in the Department of Materials Science and Engineering at Stanford University. He received his PhD in Materials Science from the FOM Institute in Amsterdam, The Netherlands, in 1998. From 1998-2001 he was a postdoctoral research fellow at the California Institute of Technology. During this time, he coined the term “Plasmonics” for a new device technology that exploits the unique optical properties of nanoscale metallic structures to route and manipulate light at the nanoscale. His current research is directed towards the development and physical analysis of nanostructured materials that find application in nanoscale electronic and photonic devices. Brongersma received a National Science Foundation Career Award, the Walter J. Gores Award for Excellence in Teaching, the International Raymond and Beverly Sackler Prize in the Physical Sciences (Physics) for his work on plasmonics, and is a Fellow of the Optical Society of America, the SPIE, and the American Physical Society.
Helen Bronte-Stewart, MD, MS
John E. Cahill Family Professor, Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsMy research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.
James D. Brooks
Keith and Jan Hurlbut Professor in the Stanford University School of Medicine
Current Research and Scholarly InterestsWe use genomic approaches to identify disease biomarkers. We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer.
Dorrell William Kirby Professor of Geology in the School of Earth Sciences, Emeritus
Current Research and Scholarly InterestsSurface and interface geochemistry; environmental fate of heavy metals; nanotechnology, applications of synchrotron radiation in geochemistry and mineralogy
Professor of Radiation Oncology, Emeritus
Current Research and Scholarly InterestsWe seek to understand the mechanisms responsible for the resistance of cancers to treatment and to develop strategies to overcome these resistances. We are using molecular and cellular techniques and mouse models to potentiate the activity of radiation on tumors by inhibiting the bone marrow rescue of the tumor vasculature following therapy.
Patrick O. Brown
Professor of Biochemistry, Emeritus
Current Research and Scholarly InterestsDr. Brown, currently an emeritus professor, is CEO and founder of Impossible Foods, a company dedicated to replacing the world's most destructive technology - the use of animals to transform plant biomass into meat, fish and dairy foods - by developing a new and better way to produce the world's most delicious, nutritious and affordable meats, fish and dairy foods directly from plants. Visit impossiblefoods.com for more information.
Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsOur lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.
Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsOne of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
Douglas L. Brutlag
Professor of Biochemistry, Emeritus
Current Research and Scholarly InterestsMy primary interest is to understand the flow of information from the genome to the phenotype of an organism. This interest includes predicting the structure and function of genes and proteins from their primary sequence, predicting function from structure simulating protein folding and ligand docking, and predicitng disease from genome variations. These goals are the same as the goals of molecular biology, however, we use primarily computational approaches.
Associate Professor of Bioengineering and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.
Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsMy major interest is in type 1 diabetes mellitus, continuous glucose sensor, and the development of an artificial pancreas. Other research interests include using continuous glucose monitoring and algorithms to control blood glucose levels in intensive care units.
Paul Buckmaster, DVM, PhD
Professor of Comparative Medicine and of Neurology
Current Research and Scholarly InterestsMechanisms of epilepsy, especially temporal lobe epilepsy.
Marguerite Blake Wilbur Professor in Natural Science and Professor of Photon Science, of Applied Physics, of Physics and Director, Stanford PULSE Institute
BioPhil Bucksbaum holds the Marguerite Blake Wilbur Chair in Natural Science at Stanford University, with appointments in Physics, Applied Physics, and in Photon Science at SLAC. He conducts his research in the Stanford PULSE Institute (https://web.stanford.edu/~phbuck). He and his wife Roberta Morris live in Menlo Park, California with their cat. Their grown daughter lives in Toronto.
Bucksbaum was born and raised in Iowa, and graduated from Harvard in 1975. He attended U.C. Berkeley on a National Science Foundation Graduate Fellowship and received his Ph.D. in 1980 for atomic parity violation experiments under Professor Eugene Commins, with whom he also has co-authored a textbook, “Weak Interactions of Leptons and Quarks.” In 1981 he joined Bell Laboratories, where he pursued new applications of ultrafast coherent radiation from terahertz to vacuum ultraviolet, including time-resolved VUV ARPES, and strong-field laser-atom physics.
He joined the University of Michigan in 1990 and stayed for sixteen years, becoming Otto Laporte Collegiate Professor and then Peter Franken University Professor. He was founding Director of FOCUS, a National Science Foundation Physics Frontier Center, where he pioneered research using ultrafast lasers to control quantum systems. He also launched the first experiments in ultrafast x-ray science at the Advanced Photon Source at Argonne National Lab. In 2006 Bucksbaum moved to Stanford and SLAC, and organized the PULSE Institute to develop research utilizing the world’s first hard x-ray free-electron laser, LCLS. In addition to directing PULSE, he has previously served as Department Chair of Photon Science and Division Director for Chemical Science at SLAC. His current research is in laser interrogation of atoms and molecules to explore and image structure and dynamics on the femtosecond scale. He currently has more than 250 publications.
Bucksbaum is a Fellow of the APS and the Optical Society, and has been elected to the National Academy of Sciences and the American Academy of Arts and Sciences. He has held Guggenheim and Miller Fellowships, and received the Norman F. Ramsey Prize of the American Physical Society for his work in ultrafast and strong-field atomic and molecular physics. He served as the Optical Society President in 2014, and also served as the President of the American Physical Society in 2020. He has led or participated in many professional service activities, including NAS studies, national and international boards, initiatives, lectureships and editorships.