Wu Tsai Human Performance Alliance
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Oliver O. Aalami, MD
Clinical Professor, Surgery - Vascular Surgery
Current Research and Scholarly InterestsWe launched a national precision medicine PAD trial called, VascTrac (http://vasctrac.stanford.edu/). This trial is mobile phone based and leverages Apple's ResearchKit Platform to monitor a patient's activity both pre- and post-intervention. We are validating mobile phone surveillance for PAD patients and are currently enrolling.
Geoffrey Abrams, MD
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Abrams' research is focused on elucidating the pathobiology behind tendinoapthy and developing new treatment modalities for the disease. Specifically, his team is studying the role of micro-RNA as it relates to chronic inflammation and stem cell differentiation in the development and perpetuation of chronic tendinopathy.
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsMy research lies in the intersection of Machine Learning, Computer Vision, Healthcare, and Computational Neuroscience.
Associate Professor (Research) of Anesthesiology, Perioperative and Pain Medicine (Adult MSD), of Pediatrics (Neonatology) and, by courtesy, of Biomedical Data Science
BioThank you for your interest. Please use the links on the bottom right side of this page to learn more about our laboratory's work.
Tayyeba K. Ali, MD
Adjunct Clinical Associate Professor, Ophthalmology
BioTayyeba K. Ali, MD, a Board Certified ophthalmologist, specializes in complex corneal disease and uveitis. She sees patients at Palo Alto Medical Foundation / Sutter Health in Sunnyvale, CA. Dr. Ali also works as a medical specialist on contract for Google.
Prior to completing two fellowships in cornea, external disease, refractive surgery and uveitis at Bascom Palmer Eye Institute, ranked #1 eye hospital in the United States by U.S. News & World Report, Dr. Ali finished her ophthalmology residency at the Jones Eye Institute / UAMS. She earned her medical degree from Emory University School of Medicine and completed her undergraduate training in English literature and creative writing from Agnes Scott College.
Dr. Ali has received many academic and teaching awards including the Bascom Palmer Fellow of the Year Award and the Jone’s Eye Dean’s Faculty Award. She has delivered dozens of lectures on the national and international level and published numerous meeting abstracts and peer-reviewed journal articles.
As a second generation American, Tayyeba finds herself dwelling on migrant and refugee stories, their need for ethnic and religious identity, and the repercussions of these journeys. She is keenly interested in international medicine, resident education, health technology and taking a closer look at the moral crossroads we face in healthcare. She is the Associated Director for Pegasus Physician Writers at Stanford as well as the Senior Fiction Editor for the medical literary magazine, The Pegasus Review; she has a particular affinity for colons (grammatically, not anatomically, speaking) and semicolons.
Russ B. Altman
Kenneth Fong Professor and Professor of Bioengineering, of Genetics, of Medicine, of Biomedical Data Science, Senior Fellow at the Stanford Institute for HAI and Professor, by courtesy, of Computer Science
Current Research and Scholarly InterestsI refer you to my web page for detailed list of interests, projects and publications. In addition to pressing the link here, you can search "Russ Altman" on http://www.google.com/
Al'ai Alvarez, MD
Clinical Associate Professor, Emergency Medicine
BioAl’ai Alvarez, MD FACEP FAAEM (@alvarezzzy) is a national leader and educator on wellness, diversity, equity, and inclusion. He is an emergency physician and clinical associate professor of Emergency Medicine (EM) at Stanford University. Dr. Alvarez is the Director of Well-Being and co-chair of the Human Potential Team at Stanford Emergency Medicine. He also serves as the Director of the first Physician Wellness Fellowship. His work focuses on humanizing physician roles as individuals and teams by harnessing the individual human potential in the context of high-performance teams. His long-term interest is to optimize the interconnectedness between Medical Education, Process Improvement (Quality and Clinical Operations), Recruitment (Diversity), and Well-being (Inclusion) through human-centered design.
Dr. Alvarez is the chair of Stanford WellMD’s Physician Wellness Forum and the director of Stanford’s peer-to-peer support for faculty and trainees, the Physician Resource Network (PRN) Support Program.
Dr. Alvarez is a faculty fellow at the Stanford Byers Center for Biodesign (2021-2022), exploring the role of mindfulness in high-stress environments. He is also the co-director and organizer for the High-Performance Resuscitation Teams Summit (https://bit.ly/HPRT2023) in collaboration with Mayo Clinic and the Mission Critical Teams Institute. HPRT aims to develop a collaborative inquiry among teams from various disciplines, including healthcare, aerospace, sports, military, special operations forces, fire rescue, and other high-performing/elite teams.
Dr. Alvarez was the associate residency program director (APD) at the Stanford Emergency Medicine Residency Program [2016-2021]. Among his roles, he served as the second-year class APD and the Medicine Without Walls (MWOW) Line Director for the Stanford Emergency Medicine ACCEL Program (https://emed.stanford.edu/residency/ACCEL.html).
Nationally, Dr. Alvarez serves on committees on physician well-being and diversity, equity, and inclusion in medical education. He is the co-chair of the Council of EM Residency Directors (CORD) Wellness Leadership Mini-Fellowship, a mentor at the Academic Life in Emergency Medicine (ALiEM) Faculty Incubator, and co-founded and co-chair of the largest national diversity mentoring program in EM through the joint American College of Emergency Physician (ACEP) ’s Diversity, Inclusion and Health Equity (DIHE) and the Emergency Medicine Residents Association (EMRA) ’s Diversity Mentorship Initiative.
Dr. Alvarez has given numerous grand rounds and national and international conference lectures and workshops on relevant topics that humanize physicians (#doctorsarehumanstoo), the importance of self-compassion and belonging in physician well-being, and efforts to advance diversity, equity, and inclusion in medicine.
Dr. Alvarez received the 2019 ACEP DIHE Distance and Impact Award, the 2020 Society for Academic Emergency Medicine (SAEM) Academy for Diversity and Inclusion in Emergency Medicine (ADIEM) Outstanding Academician Award, the 2020 CORD Academy for Scholarship in Education in EM Academy Member Award on Teaching and Evaluation, and the 2022 John Levin Leadership Award at Stanford Health Care.
Associate Professor of Materials Science and Engineering, Senior Fellow at the Woods Institute for the Environment and Associate Professor, by courtesy, of Pediatrics (Endocrinology)
Current Research and Scholarly InterestsThe underlying theme of the Appel Lab at Stanford University integrates concepts and approaches from supramolecular chemistry, natural/synthetic materials, and biology. We aim to develop supramolecular biomaterials that exploit a diverse design toolbox and take advantage of the beautiful synergism between physical properties, aesthetics, and low energy consumption typical of natural systems. Our vision is to use these materials to solve fundamental biological questions and to engineer advanced healthcare solutions.
Euan A. Ashley
Associate Dean, School of Medicine, Roger and Joelle Burnell Professor of Genomics and Precision Health, Professor of Medicine (Cardiovascular Medicine), of Genetics, of Biomedical Data Science and, by courtesy, of Pathology
Current Research and Scholarly InterestsThe Ashley lab is focused on precision medicine. We develop methods for the interpretation of whole genome sequencing data to improve the diagnosis of genetic disease and to personalize the practice of medicine. At the wet bench, we take advantage of cell systems, transgenic models and microsurgical models of disease to prove causality in biological pathways and find targets for therapeutic development.
Themistocles (Tim) Assimes
Associate Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsGenetic Epidemiology, Genetic Determinants of Complex Traits related to Cardiovasular Medicine, Coronary Artery Disease related pathway analyses and integrative genomics, Mendelian randomization studies, risk prediction for major adverse cardiovascular events, cardiovascular medicine related pharmacogenomics, ethnic differences in the determinants of Insulin Mediated Glucose Uptake, pharmacoepidemiology of cardiovascular drugs & outcomes
Stephen A. Baccus
Professor of Neurobiology
Current Research and Scholarly InterestsWe study how the neural circuitry of the vertebrate retina encodes visual information and performs computations. To control and measure the retinal circuit, we present visual images while performing simultaneous two-photon imaging and multielectrode recording. We perturb the circuit as it operates using simultaneous intracellular current injection and multielectrode recording, and use the resulting large data sets to construct models of retinal computation.
Fred M Baik, MD
Assistant Professor of Otolaryngology - Head & Neck Surgery (OHNS)
BioDr. Baik is Assistant Professor of Otolaryngology – Head & Neck Surgery at Stanford University. He provides comprehensive surgical care for patients with head and neck cancer, both as an ablative and reconstructive surgeon. His clinical interests include oral cavity cancer, complex skin cancer, microvascular reconstruction and the diagnosis and management of nodal metastasis. With his background in fluorescence imaging, Dr. Baik’s research focuses on surgical navigation using targeted agents to improve tumor margin assessment and the detection of nodal metastasis, and he currently leads several clinical trials to translate novel imaging techniques.
Dr. Baik graduated with honors in Biology at the University of Pennsylvania and received his medical degree at UC San Diego. After completing his Otolaryngology residency at the University of Washington, he pursued advanced training in Head and Neck Oncology & Reconstructive Surgery at Mount Sinai Beth Israel Hospital in New York City. He is a board-certified by the American Board of Otolaryngology, and a member of the American Head and Neck Society, American Academy of Otolaryngology – Head and Neck Surgery, and a fellow of the American College of Surgeons.
Thomas More Storke Professor, Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of EducationOn Leave from 10/01/2023 To 06/30/2024
BioJeremy Bailenson is founding director of Stanford University’s Virtual Human Interaction Lab, Thomas More Storke Professor in the Department of Communication, Professor (by courtesy) of Education, Professor (by courtesy) Program in Symbolic Systems, and a Senior Fellow at the Woods Institute for the Environment. He has served as Director of Graduate Studies in the Department of Communication for over a decade. He earned a B.A. from the University of Michigan in 1994 and a Ph.D. in cognitive psychology from Northwestern University in 1999. He spent four years at the University of California, Santa Barbara as a Post-Doctoral Fellow and then an Assistant Research Professor.
Bailenson studies the psychology of Virtual and Augmented Reality, in particular how virtual experiences lead to changes in perceptions of self and others. His lab builds and studies systems that allow people to meet in virtual space, and explores the changes in the nature of social interaction. His most recent research focuses on how virtual experiences can transform education, environmental conservation, empathy, and health. He is the recipient of the Dean’s Award for Distinguished Teaching at Stanford. In 2020, IEEE recognized his work with “The Virtual/Augmented Reality Technical Achievement Award”.
He has published more than 200 academic papers, spanning the fields of communication, computer science, education, environmental science, law, linguistics, marketing, medicine, political science, and psychology. His work has been continuously funded by the National Science Foundation for over 25 years.
His first book Infinite Reality, co-authored with Jim Blascovich, emerged as an Amazon Best-seller eight years after its initial publication, and was quoted by the U.S. Supreme Court. His new book, Experience on Demand, was reviewed by The New York Times, The Wall Street Journal, The Washington Post, Nature, and The Times of London, and was an Amazon Best-seller.
He has written opinion pieces for The Washington Post, The Wall Street Journal, Harvard Business Review, CNN, PBS NewsHour, Wired, National Geographic, Slate, The San Francisco Chronicle, TechCrunch, and The Chronicle of Higher Education, and has produced or directed six Virtual Reality documentary experiences which were official selections at the Tribeca Film Festival. His lab has exhibited VR in hundreds of venues ranging from The Smithsonian to The Superbowl.
Associate Professor of Epidemiology and Population Health and, by courtesy, of Statistics and of Medicine (Stanford Prevention Research Center)
BioProfessor Baiocchi is a PhD statistician in Stanford University's Epidemiology and Population Health Department. He thinks a lot about behavioral interventions and how to rigorously evaluate if and how they work. Methodologically, his work focuses on creating statistically rigorous methods for causal inference that are transparent and easy to critique. He designed -- and was the principle investigator for -- two large randomized studies of interventions to prevent sexual assault in the settlements of Nairobi, Kenya.
Professor Baiocchi is an interventional statistician (i.e., grounded in both the creation and evaluation of interventions). The unifying idea in his research is that he brings rigorous, quantitative approaches to bear upon messy, real-world questions to better people's lives.
Assistant Professor of Chemistry
BioSteven Banik’s research interests center on rewiring mammalian biology and chemical biotechnology development using molecular design and construction. Projects in the Banik lab combine chemical biology, organic chemistry, protein engineering, cell and molecular biology to precisely manipulate the biological machines present in mammalian cells. Projects broadly aim to perform new functions that shed light on regulatory machinery and the potential scope of mammalian biology. A particular focus is the study of biological mechanisms that can be coopted by synthetic molecules (both small molecules and proteins). These concepts are applied to develop new therapeutic strategies for treating aging-related disorders, genetic diseases, and cancer.
Prior to joining the faculty at Stanford, Steven was a NIH and Burroughs CASI postdoctoral fellow advised by Prof. Carolyn Bertozzi at Stanford. His postdoctoral research developed approaches for targeted protein degradation from the extracellular space with lysosome targeting chimeras (LYTACs). He received his Ph.D. from Harvard University in 2016, where he worked with Prof. Eric Jacobsen on synthetic methods for the selective, catalytic difluorination of organic molecules and new approaches for generating and controlling reactive cationic intermediates in asymmetric catalysis.
K. K. Lee Professor and Professor, by courtesy, of Materials Science and Engineering and of Chemistry
BioZhenan Bao joined Stanford University in 2004. She is currently a K.K. Lee Professor in Chemical Engineering, and with courtesy appointments in Chemistry and Material Science and Engineering. She was the Department Chair of Chemical Engineering from 2018-2022. She founded the Stanford Wearable Electronics Initiative (eWEAR) and is the current faculty director. She is also an affiliated faculty member of Precourt Institute, Woods Institute, ChEM-H and Bio-X. Professor Bao received her Ph.D. degree in Chemistry from The University of Chicago in 1995 and joined the Materials Research Department of Bell Labs, Lucent Technologies. She became a Distinguished Member of Technical Staff in 2001. Professor Bao currently has close to 700 refereed publications and more than 80 US patents with a Google Scholar H-index 201.
Bao is a member of the US National Academy of Engineering, the American Academy of Arts and Sciences and the National Academy of Inventors. Bao was elected a foreign member of the Chinese Academy of Science in 2021. She is a Fellow of AAAS, ACS, MRS, SPIE, ACS POLY and ACS PMSE.
Bao is a member of the Board of Directors for the Camille and Dreyfus Foundation from 2022. She served as a member of Executive Board of Directors for the Materials Research Society and Executive Committee Member for the Polymer Materials Science and Engineering division of the American Chemical Society. She was an Associate Editor for the Royal Society of Chemistry journal Chemical Science, Polymer Reviews and Synthetic Metals. She serves on the international advisory board for Advanced Materials, Advanced Energy Materials, ACS Nano, Accounts of Chemical Reviews, Advanced Functional Materials, Chemistry of Materials, Chemical Communications, Journal of American Chemical Society, Nature Asian Materials, Materials Horizon and Materials Today. She is one of the Founders and currently sits on the Board of Directors of C3 Nano Co. and PyrAmes, both are silicon valley venture funded companies.
Bao was a recipient of the VinFuture Prize Female Innovator 2022, ACS Award of Chemistry of Materials 2022, MRS Mid-Career Award in 2021, AICHE Alpha Chi Sigma Award 2021, ACS Central Science Disruptor and Innovator Prize in 2020, ACS Gibbs Medal in 2020, the Wilhelm Exner Medal from the Austrian Federal Minister of Science in 2018, the L'Oreal UNESCO Women in Science Award North America Laureate in 2017. She was awarded the ACS Applied Polymer Science Award in 2017, ACS Creative Polymer Chemistry Award in 2013 ACS Cope Scholar Award in 2011. She is a recipient of the Royal Society of Chemistry Beilby Medal and Prize in 2009, IUPAC Creativity in Applied Polymer Science Prize in 2008, American Chemical Society Team Innovation Award 2001, R&D 100 Award, and R&D Magazine Editors Choice Best of the Best new technology for 2001.
Annelise E. Barron
Associate Professor of Bioengineering
Current Research and Scholarly InterestsBiophysical mechanisms of host defense peptides (a.k.a. antimicrobial peptides) and their peptoid mimics; also, molecular and cellular biophysics of human innate immune responses.
Baker Family Director of Sarafan ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology and of Radiology
BioProfessor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.
Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosaccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford University in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering & Medicine for Human Health). She is now the Baker Family Director of Stanford ChEM-H.
Named a MacArthur Fellow in 1999, Dr. Bertozzi has received many awards for her dedication to chemistry, and to training a new generation of scientists fluent in both chemistry and biology. She has been elected to the Institute of Medicine, National Academy of Sciences, and American Academy of Arts and Sciences; and received the Lemelson-MIT Prize, the Heinrich Wieland Prize, the ACS Award in Pure Chemistry, and the Chemistry of the Future Solvay Prize, among others.
The Bertozzi Group develops chemical tools to study the glycobiology underlying diseases such as cancer, inflammation, tuberculosis and most recently COVID-19. She is the inventor of "bioorthogonal chemistry", a class of chemical reactions compatible with living systems that enable molecular imaging and drug targeting. Her group also developed new therapeutic modalities for targeted degradation of extracellular biomolecules, such as antibody-enzyme conjugates and Lysosome Targeting Chimeras (LYTACs). As well, her group studies NGly1 deficiency, a rare genetic disease characterized by loss of the human N-glycanase.
Several of the technologies developed in the Bertozzi lab have been adapted for commercial use. Actively engaged with several biotechnology start-ups, Dr. Bertozzi cofounded Redwood Bioscience, Enable Biosciences, Palleon Pharmaceuticals, InterVenn Bio, OliLux Bio, Grace Science LLC and Lycia Therapeutics. She is also a member of the Board of Directors of Lilly.
Achintya K. Bhowmik, PhD
Adjunct Professor, OHNS/Otology & Neurotology Division
BioDr. Achin Bhowmik serves on the faculty of Stanford University as an adjunct professor at the Stanford School of Medicine, where he advises research and lectures in the areas of sensory augmentation, computational perception, cognitive neuroscience, and intelligent systems. He is also an affiliate faculty member of the Stanford Institute for Human-Centered Artificial Intelligence, Wu Tsai Neurosciences Institute and Human Performance Alliance, and a mentor for the Stanford Institutes of Medicine Summer Research Program.
Dr. Bhowmik is the chief technology officer and executive vice president of engineering at Starkey Hearing Technologies, a privately-held medical devices company with over 5,000 employees and operations in over 100 countries worldwide. In this role, he is responsible for the company’s technology strategy, research and development, engineering and program management departments, and leading the drive to transform hearing aids into multifunction wearable health and communication devices with advanced sensors and artificial intelligence.
Previously, Dr. Bhowmik was the vice president and general manager of the Perceptual Computing Group at Intel Corporation, where he was responsible for the R&D, engineering, operations, and businesses in the areas of 3D sensing and interactive computing, computer vision and artificial intelligence, autonomous robots and drones, and immersive virtual and merged reality devices.
Dr. Bhowmik is a member of the Forbes Technology Council, board of trustees for the National Captioning Institute, board of directors for OpenCV, board of advisors for the Fung Institute for Engineering Leadership at the University of California, Berkeley, and industry advisory board for the Institute for Engineering in Medicine and Biomedical Engineering at the University of Minnesota. He is also on the board of directors and advisors for several technology startup companies.
He has also held adjunct and guest professor positions at the University of California, Berkeley, Liquid Crystal Institute of the Kent State University, Kyung Hee University, Seoul, and the Indian Institute of Technology, Gandhinagar. He received his Bachelor of Technology from the Indian Institute of Technology, Kanpur, PhD from Auburn University, and attended the Executive Program at Stanford University. He has authored over 200 publications, including two books and over 80 granted patents.
His awards and honors include Fellow of the Institute of Electrical and Electronics Engineers (IEEE), Fellow of the Asia-Pacific Artificial Intelligence Association (AAIA), President and Fellow of the Society for Information Display (SID), Top 25 Healthcare Technology CTOs by the Healthcare Technology Report, Notable Leaders in Healthcare by Twin Cities Business, Healthcare Heroes award from the Business Journals, Industrial Distinguished Leader award from the Asia-Pacific Signal and Information Processing Association, IEEE Distinguished Industry Speaker, TIME’s Best Inventions, Red Dot Design award, MUSE Design award, and the Artificial Intelligence Excellence award.
Dr. Bhowmik and his work have been covered in numerous press articles, including TIME, Fortune, Wired, USA Today, US News & World Reports, Wall Street Journal, CBS News, BBC, Forbes, Bloomberg Businessweek, Scientific American, Popular Mechanics, MIT Technology Review, EE Times, The Verge, etc.
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsThe long-term goal of our research is to understand the fundamental mechanisms that govern and reprogram cellular fate during development, regeneration and disease.
UPS Foundation Professor and Senior Fellow at the Woods Institute for the Environment
BioOur group focuses on understanding the impact of building design and materials on human wellbeing, developing design tools to quantify nature experience in buildings, and understanding the role of the built environment in public perceptions of and support for affordable housing. We explore how buildings can include both physical and digital adaptations to improve wellbeing outcomes including new methods of bringing nature and the experience of nature into buildings. We are interested in how building management systems can be extended beyond providing energy savings, thermal comfort, and security to support and maintain a broader set of human wellbeing outcomes while preserving occupant privacy. Further, we are studying the impact of built features, including historic structures, on community wellbeing and methods of design for community wellbeing that support the equitable development of affordable and permanent supportive housing. While not longer active in this area, our group also has a long history of expertise in the design and evaluation of sustainable, durable construction materials, their application to structures and construction, including damage-tolerant, high-performance fiber-reinforced cementitious composite materials, and bio-based fiber-reinforced polymeric composites and insulating foams that have a closed loop life-cycle.
Helen M. Blau
Donald E. and Delia B. Baxter Foundation Professor, Director, Baxter Laboratory for Stem Cell Biology and Professor, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
George E. and Lucy Becker Professor in Medicine
Current Research and Scholarly InterestsThe major goal of our research is to gain insight into the prevention and control of HIV and other viral pathogens by studying the interplay between the virus and the host immune response. We investigate the role of various arms of the immune response, but with a particular focus on NK cells. We hope to gain additional insights into control of infectious diseases by studying how pregnancy modulates immune responses.
Charles and Elizabeth Prothro Professor of Marine Sciences, Professor of Oceans and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsThermal physiology, open ocean predators, ecological physiology and tuna biology
Stephen Harris Professor and Professor of Materials Science and Engineering and, by courtesy, of Applied Physics
BioMark Brongersma is a Professor in the Department of Materials Science and Engineering at Stanford University. He received his PhD in Materials Science from the FOM Institute in Amsterdam, The Netherlands, in 1998. From 1998-2001 he was a postdoctoral research fellow at the California Institute of Technology. During this time, he coined the term “Plasmonics” for a new device technology that exploits the unique optical properties of nanoscale metallic structures to route and manipulate light at the nanoscale. His current research is directed towards the development and physical analysis of nanostructured materials that find application in nanoscale electronic and photonic devices. Brongersma received a National Science Foundation Career Award, the Walter J. Gores Award for Excellence in Teaching, the International Raymond and Beverly Sackler Prize in the Physical Sciences (Physics) for his work on plasmonics, and is a Fellow of the Optical Society of America, the SPIE, and the American Physical Society.
Helen Bronte-Stewart, MD, MS
John E. Cahill Family Professor, Professor of Neurology and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.
Vivek P. Buch, MD
Assistant Professor of Neurosurgery
BioDr. Buch is a neurosurgeon with fellowship training in epilepsy, functional, and minimally invasive neurosurgery. He is a clinical assistant professor in the Department of Neurosurgery of Stanford University School of Medicine.
Dr. Buch focuses his expertise on the open and minimally invasive treatment of epilepsy, low grade brain tumors, movement and neuropsychiatric disorders, facial and body pain syndromes, and other complex neurological conditions. He uses advanced and innovative techniques to treat both adult and pediatric patients. For each patient, he develops a personalized care plan that is designed to be both comprehensive and compassionate.
Dr. Buch has conducted extensive research. His career goal is to develop restorative bioengineering approaches for complex neurocognitive, neurodevelopmental, and neuropsychiatric disorders. He is creating network-neuroprosthetics and focused ultrasound delivery mechanisms for precision cellular, gene, and molecular therapies to restore abnormal brain circuit function in these vulnerable patient populations. He is further pioneering novel intraoperative technologies including personalized network-based targeting, holographic mixed reality, and artificial intelligence platforms for minimally invasive cranial surgery.
He has co-authored articles on his research discoveries in Nature Medicine, Neuron, Brain, Annals of Surgery, Frontiers in Neuroscience, Epilepsia, Brain Stimulation, Stereotactic and Functional Neurosurgery, Surgical Innovation, Frontiers in Surgery, Journal of Neurosurgery, and many other journals. Articles focus on developing novel network control theory applications to human brain functions and new techniques and technologies to enhance neurosurgical effectiveness and patient outcomes.
He is the Section Editor for NEUROSURGERY, and a guest editor for Surgical Innovation and Brain Sciences. He also has co-authored chapters in the books Neurosurgical Atlas, Operative Techniques in Epilepsy Surgery, Deep Brain Stimulation, and The Encyclopedia of Medical Robotics.
Dr. Buch has presented the findings of his research at the national conferences of numerous professional associations. Among them are the American Association of Neurological Surgeons, Society for Neuroscience, Congress of Neurological Surgeons, and Society for Imaging Informatics in Medicine. Topics include understanding network mechanisms of cognitive control and advances in the use of augmented reality technology to enhance neurosurgical approaches.
For his clinical, research, and academic achievements. Dr. Buch has earned many honors. He has won awards from the American Association of Neurological Surgeons, American Roentgen Ray Society, Congress of Neurological Surgeons, and National Institutes of Health.
Dr. Buch is a member of the American Association of Neurological Surgeons, Congress of Neurological Surgeons, World Society for Stereotactic and Functional Neurosurgery, American Association of Stereotactic and Functional Neurosurgery, and Alpha Omega Alpha Medical Honor Society.
He holds patents on such topics as artificial intelligence systems designed to help guide surgery and neural control signals for behavioral modification and closed-loop stimulation therapy.
Marion S. Buckwalter, MD, PhD
Professor of Neurology and of Neurosurgery
Current Research and Scholarly InterestsThe goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic and clinical research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how they affect short-term brain injury and long term outcomes like dementia and depression.
Clinical Associate Professor, Psychiatry and Behavioral Sciences
BioMy research focuses on brain mechanisms underlying cognitive deficits in two distinct populations: children with neurodevelopmental disorders, especially kids with ADHD, and elders with neurodegenerative diseases, such as Parkinson's disease. By integrating cognitive, neuroscience, and computational models with advanced functional neuroimaging techniques, my goal is to understand the neurocognitive factors that contribute to typical and atypical brain development and aging.
Associate Professor of Bioengineering and, by courtesy, of Neurosurgery
BioDavid B. Camarillo is Associate Professor of Bioengineering, (by courtesy) Mechanical Engineering and Neurosurgery at Stanford University. Dr. Camarillo holds a B.S.E in Mechanical and Aerospace Engineering from Princeton University, a Ph.D. in Mechanical Engineering from Stanford University and completed postdoctoral fellowships in Biophysics at the UCSF and Biodesign Innovation at Stanford. Dr. Camarillo worked in the surgical robotics industry at Intuitive Surgical and Hansen Medical, before launching his laboratory at Stanford in 2012. His current research focuses on precision human measurement for multiple clinical and physiological areas including the brain, heart, lungs, and reproductive system. Dr. Camarillo has been awarded the Hellman Fellowship, the Office of Naval Research Young Investigator Program award, among other honors including multiple best paper awards in brain injury and robotic surgery. His research has been funded by the NIH, NSF, DoD, as well as corporations and private philanthropy. His lab’s research has been featured on NPR, the New York Times, The Washington Post, Science News, ESPN, and TED.com as well as other media outlets aimed at education of the public.
Clinical Professor, Pediatrics - Adolescent Medicine
BioJennifer Carlson, MD, is a Clinical Professor of Pediatrics in the division of Adolescent Medicine at Stanford. During her time at Stanford, she has served in a range of both clinical roles (providing care in the ambulatory, inpatient, and consultative services) and educational roles (serving as rotation director, pediatric resident coach, program director for Adolescent Medicine fellowship, member of the Fellows in Adolescent Medicine Learning Initiative (FAMLI)). She has led/collaborated on program initiatives with the goal of improving health access, particularly for the adolescent-aged population. These programs have included the Virtual PrEP clinic, inpatient Reproductive Consultation service, outpatient Joint Reproductive Health clinics, and Eating Disorders Telehealth program.
In addition to Adolescent Medicine, Dr. Carlson is board-certified in Clinical Informatics. She has served as the Medical Director of Patients Portals since 2016 and is a member of the Epic Adolescent Medicine Steering Board/BrainTrust. In her role as Clinical Informaticist, she has worked to expand and enhance information access for patients and families and published widely on novel approaches to portal development and management of confidentiality within the electronic health record (EHR). She has collaborated on the Epic White paper for managing confidentiality within the EHR and co-authored a multi-organization position statement on the topic.
Operationally, Dr. Carlson has held positions as physician-at-large for the LPCH Executive committee, Medical Director of the South Bay clinics, and member of the Operations Leadership Steering committee for the hospital.
Specific areas of interest and scholarship include:
1)Improving health equity and health access for the pediatric population- particularly for the adolescent and young adult age range- through novel program development (such as Virtual PrEP clinic).
2)Developing foundational and systemic approaches to managing health information within the EHR to allow for optimal health care for all patients. This includes ensuring that private and confidential information is protected within the electronic health record and non-private information is easily accessible to patients and families.
3)Improving systems for screening and management of psychosocial factors that affect the health of youth and families (ie, social determinants of health, universal depression screening, etc).
Donald E. Knuth Professor and Professor, by courtesy, of Mathematics
Current Research and Scholarly InterestsEfficient algorithmic techniques for processing, searching and indexing massive high-dimensional data sets; efficient algorithms for computational problems in high-dimensional statistics and optimization problems in machine learning; approximation algorithms for discrete optimization problems with provable guarantees; convex optimization approaches for non-convex combinatorial optimization problems; low-distortion embeddings of finite metric spaces.
Assistant Professor (Research) of Radiology (Integrative Biomedical Imaging Informatics at Stanford) and, by courtesy, of Biomedical Data Science
Current Research and Scholarly InterestsDr. Chaudhari is interested in the application of artificial intelligence techniques to all aspects of medical imaging, including automated schedule and reading prioritization, image reconstruction, quantitative analysis, and prediction of patient outcomes. His interests range from developing novel data-efficient machine learning algorithms to clinical deployment and validation of patient outcomes. He is also exploring combining imaging with clinical, natural language, and time series data.
Associate Professor of Mechanical Engineering and, by courtesy, of BioengineeringOn Partial Leave from 10/01/2023 To 06/30/2024
Current Research and Scholarly InterestsWe study the physics of cell migration, division, and morphogenesis in 3D, as well cell-matrix mechanotransduction, or the process by which cells sense and respond to mechanical properties of the extracellular matrices. For both these areas, we use engineered biomaterials for 3D culture as artificial extracellular matrices.
John R. Adler Professor, Professor of Neurosurgery and of Ophthalmology and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsFunctional circuitry of the retina and design of retinal prostheses
Eun Young Choi, PhD
Current Research and Scholarly InterestsDr. Choi is broadly interested in mapping the brain’s connectivity and characterizing its functional dynamics using advanced neuroimaging and clinical neurophysiological methods, as well as utilizing this information to identify individual-specific neurosurgical targets for neuromodulation (e.g., deep brain stimulation). Her prior work has mapped the functional and connectional organization of the striatum using neuroimaging and neuroanatomical connectivity methods. She is currently focused on the use of thalamic deep brain stimulation to improve memory and attention in traumatic brain injury and Alzheimer’s disease.
Constance Chu, MD
Professor of Orthopaedic Surgery (Sports Medicine)
BioDr. Constance R. Chu is Professor and Vice Chair Research, in the Department of Orthopedic Surgery at Stanford University. She is also Director of the Joint Preservation Center and Chief of Sports Medicine at the VA Palo Alto. Previously, she was the Albert Ferguson Endowed Chair and Professor of Orthopaedic Surgery at the University of Pittsburgh. She is a clinician-scientist who is both principal investigator of several projects funded by the National Institutes of Health and who has been recognized as a Castle-Connelly/US News and World Report “Top Doctor” in Orthopedic Surgery as well as on Becker’s list of Top Knee Surgeons in the United States. Her clinical practice focuses on the knee: primarily restoration and reconstruction of the ACL, menisci and cartilage. She graduated from the U.S. Military Academy at West Point and earned her medical degree from Harvard Medical School.
As Director of the multi-disciplinary Joint Preservation Center structured to seamlessly integrate the latest advances in biologics, mechanics, and imaging with comprehensive patient centered musculoskeletal and orthopedic care, Dr. Chu aims to develop a new model for health care delivery, research and education with an emphasis on health promotion and prevention. Cornerstones of this program include teamwork and a focus on personalized medicine. A central goal is to transform the clinical approach to osteoarthritis from palliation to prevention. In addition to optimizing clinical operations, outstanding research is critical to developing more effective new treatments. Towards this end, Dr. Chu is leading innovative translational research from bench to bedside in three main areas: quantitative imaging and biomarker development for early diagnosis and staging of joint and cartilage injury and degeneration; cartilage tissue engineering and stem cell based cartilage repair; and molecular and biological therapies for joint restoration and joint rejuvenation. Her research efforts have led to more than 30 professional awards and honors to include a Kappa Delta Award, considered to be the highest research honor in Orthopedic Surgery.
Dr. Chu also regularly holds leadership and committee positions in major professional organizations such as the American Association of Orthopedic Surgeons (AAOS) and the American Orthopedic Association (AOA). In her subspecialty of Orthopedic Sports Medicine, she is a past President of the Forum Sports Focus Group, a member of the Herodicus Society of leaders in Sports Medicine, and immediate past Chair of the American Orthopedic Society for Sports Medicine (AOSSM) Research Council. She is alumnus of the AOA American, British, Canadian (ABC) and the AOSSM Traveling Fellowships.
Daniel Eugene Clark
Clinical Assistant Professor, Medicine - Cardiovascular Medicine
Clinical Assistant Professor, Pediatrics - Cardiology
BioDr. Clark completed a 4-year MD/MPH program at the University of Texas Health Science Center in San Antonio. He subsequently completed all of his post-graduate training at Vanderbilt University Medical Center (VUMC), including Internal Medicine-Pediatrics, Adult Cardiology, and Adult Congenital Heart Disease (ACHD). Additionally, he served as Chief Fellow of the Vanderbilt Cardiovascular Medicine Fellowship, trained in multimodality cardiovascular imaging, and conducted clinical research during a two-year NIH-funded T32 research fellowship at VUMC.
Prior to joining the Stanford ACHD faculty, he was appointed Instructor of Cardiovascular Medicine at Vanderbilt and read cardiac magnetic resonance (CMR) imaging as an attending for two years. He is appointed Assistant Professor of Medicine and Pediatrics at Stanford University School of Medicine.
His academic and investigative interests focus on advanced cardiovascular imaging for ACHD patients, particularly the application of CMR in this population. During the COVID-19 pandemic, Dr. Clark pivoted his scholarly efforts to focus on studying the cardiovascular effects of COVID-19 with CMR. His current clinical investigations include understanding the CMR-derived diastolic patterns of Fontan physiology and the effect of cardiac rehabilitation on functional status among patients with Fontan failure.
Associate Professor of Bioengineering and, by courtesy, of Electrical Engineering
BioTodd P. Coleman is an Associate Professor in the Department of Bioengineering, and by courtesy, Electrical Engineering at Stanford University. He received B.S. degrees in electrical engineering (summa cum laude), as well as computer engineering (summa cum laude) from the University of Michigan (Go Blue). He received M.S. and Ph.D. degrees from MIT in electrical engineering and computer science. He did postdoctoral studies at MIT and Mass General Hospital in quantitative neuroscience. He previously was a faculty member in the Departments of Electrical & Computer Engineering and Bioengineering at the University of Illinois, Urbana-Champaign, and the University of California, San Diego, respectively. Dr. Coleman’s research is very multi-disciplinary, using tools from applied probability, physiology, and bioelectronics. Examples include, for instance, optimal transport methods in high-dimensional uncertainty quantification and developing technologies and algorithms to monitor and modulate physiology of the nervous systems in the brain and visceral organs. He has served as a Principal Investigator on grants from the NSF, NIH, Department of Defense, and multiple private foundations. Dr. Coleman is an inventor on 10 granted US patents. He has been selected as a Gilbreth Lecturer for the National Academy of Engineering, a TEDMED speaker, and a Fellow of IEEE as well as the American Institute for Medical and Biological Engineering. He is currently the Chair of the National Academies Standing Committee on Biotechnology Capabilities and National Security Needs.
Steven Hartley Collins
Associate Professor of Mechanical Engineering and, by courtesy, of Bioengineering
BioSteve Collins is an Associate Professor of Mechanical Engineering at Stanford University, where he teaches courses on design and robotics and directs the Stanford Biomechatronics Laboratory. His primary focus is to speed and systematize the design and prescription of prostheses and exoskeletons using versatile device emulator hardware and human-in-the-loop optimization algorithms (Zhang et al. 2017, Science). Another interest is efficient autonomous devices, such as highly energy-efficient walking robots (Collins et al. 2005, Science) and exoskeletons that use no energy yet reduce the metabolic energy cost of human walking (Collins et al. 2015, Nature).
Prof. Collins received his B.S. in Mechanical Engineering in 2002 from Cornell University, where he performed undergraduate research on passive dynamic walking robots. He received his Ph.D. in Mechanical Engineering in 2008 from the University of Michigan, where he performed research on the dynamics and control of human walking. He performed postdoctoral research on humanoid robots at T. U. Delft in the Netherlands. He was a professor of Mechanical Engineering and Robotics at Carnegie Mellon University for seven years. In 2017, he joined the faculty of Mechanical Engineering at Stanford University.
Prof. Collins is a member of the Scientific Board of Dynamic Walking and the Editorial Board of Science Robotics. He has received the Young Scientist Award from the American Society of Biomechanics, the Best Medical Devices Paper from the International Conference on Robotics and Automation, and the student-voted Professor of the Year in his department.
David N. Cornfield
Anne T. and Robert M. Bass Professor of Pediatric Pulmonary Medicine and Professor, by courtesy, of Surgery
Current Research and Scholarly InterestsOver the past 20 years, the Cornfield Laboratory has focused upon basic, translational and clinical research, with a primary focus on lung biology. As an active clinician-scientist, delivering care to acutely and chronically ill infants and children, our lab focuses on significant clinical challenges and tried to use science to craft novel solutions to difficult clinical problems.
Associate Professor of Psychology and, by courtesy, of Medicine (Primary Care & Population Health)
Current Research and Scholarly InterestsOur lab focuses on how subjective mindsets (e.g., thoughts, beliefs and expectations) can alter objective reality through behavioral, psychological, and physiological mechanisms. We are interested in understanding how mindsets affect important outcomes both within and beyond the realm of medicine, in the domains such as exercise, diet and stress. https://mbl.stanford.edu/
Francesco Nandkumar Dandekar
Clinical Assistant Professor, Psychiatry and Behavioral Sciences
BioDr. Dandekar is the Associate Director of Sports Psychiatry and a Clinical Assistant Professor at Stanford University. After graduating summa cum laude from the University of Southern California with a B.S. in Biomedical Engineering, he earned a Regents Scholarship to complete his M.D. at UC San Diego, where he received the American Academy of Neurology’s Prize for Excellence. During his residency and fellowship at Stanford, Dr. Dandekar provided care to a variety of patients utilizing a combination of medication management, psychotherapy, and lifestyle changes (sleep, nutrition, exercise, recovery). Teamed with Clinical Professor Dr. Douglas Noordsy, he helped to incorporate psychiatric services into Stanford's sports psychology program, and continues to see elite athletes as part of the Stanford Sports Psychiatry Clinic. He also specializes in treating physicians, and sees many residents, fellows, and attendings in his private practice. In his free time, he enjoys playing tennis, chess, and guitar.
Professor of Radiology (Body Imaging) and, by courtesy, of BioengineeringOn Partial Leave from 11/22/2023 To 12/22/2023
Current Research and Scholarly Interests1. MRI of Breast Cancer, particularly new techniques. Currently being explored are techniques including ultra high spatial resolution MRI and contrast-agent-free detection of breast tumors.
2. MRI-guided interventions, especially MRI-compatible remote manipulation and haptics
3. Medical Mixed Reality. Currently being explored are methods of fusing patients and their images to potentially improve breast conserving surgery, and other conditions.
Professor of Anesthesiology, Perioperative and Pain Medicine (Adult Pain) and, by courtesy, of Psychiatry and Behavioral Sciences (General Psychiatry & Psychology (Adult))
Current Research and Scholarly InterestsThe Stanford Pain Relief Innovations Lab is dedicated to better characterizing and treating pain with patient-centered solutions. We specialize in the conduct of large-scale acute and chronic pain clinical trials that aim to (1) expand and scale access to behavioral medicine via digital and brief treatments; (2) reduce opioid risks via reduction for some and improved opioid access for others; (3) equip healthcare providers with brief behavioral medicine interventions to optimize health outcomes.
Ruth G. and William K. Bowes Professor in the School of Engineering
BioDauskardt and his group have worked extensively on integrating new materials into emerging technologies including thin-film structures for nanoscience and energy technologies, high-performance composite and laminates for aerospace, and on biomaterials and soft tissues in bioengineering. His group has pioneered methods for characterizing adhesion and cohesion of thin films used extensively in device technologies. His research on wound healing has concentrated on establishing a biomechanics framework to quantify the mechanical stresses and biologic responses in healing wounds and define how the mechanical environment affects scar formation. Experimental studies are complimented with a range of multiscale computational capabilities. His research includes interaction with researchers nationally and internationally in academia, industry, and clinical practice.
John W. Day, MD, PhD
Professor of Neurology, of Pediatrics (Genetics) and, by courtesy, of Pathology
Current Research and Scholarly InterestsOur Neuromuscular Division coordinates a comprehensive effort to conquer peripheral nerve and muscle disorders, including the muscular dystrophies, motor neuron disorders, neuromuscular junction abnormalities, and peripheral neuropathies. With patients and families foremost in mind, we have had success defining and combating these diseases, with research focused on identifying genetic causes, developing novel treatment, and maximizing patient function by optimizing current management.
Luis de Lecea
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical and Translational Neurosciences Incubator)
Current Research and Scholarly InterestsMy lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction.
Scott L. Delp, Ph.D.
Director, Wu Tsai Human Performance Alliance at Stanford, James H. Clark Professor in the School of Engineering, Professor of Bioengineering, of Mechanical Engineering and, by courtesy, of Orthopaedic Surgery
Current Research and Scholarly InterestsExperimental and computational approaches to study human movement. Development of biomechanical models to analyze muscle function, study movement abnormalities, design medical products, and guide surgery. Imaging and health technology development. Discovering the principles of peak performance to advance human health. Human performance research. Wearable technologies, video motion capture, and machine learning to enable large-scale analysis.
Joseph M. DeSimone
Sanjiv Sam Gambhir Professor of Translational Medicine, Professor of Chemical Engineering and, by courtesy, of Chemistry, of Materials Science and Engineering, and of Operations, Information and Technology at the Graduate School of Business
BioJoseph M. DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering at Stanford University. He holds appointments in the Departments of Radiology and Chemical Engineering with courtesy appointments in the Department of Chemistry and in Stanford’s Graduate School of Business.
The DeSimone laboratory's research efforts are focused on developing innovative, interdisciplinary solutions to complex problems centered around advanced polymer 3D fabrication methods. In Chemical Engineering and Materials Science, the lab is pursuing new capabilities in digital 3D printing, as well as the synthesis of new polymers for use in advanced additive technologies. In Translational Medicine, research is focused on exploiting 3D digital fabrication tools to engineer new vaccine platforms, enhanced drug delivery approaches, and improved medical devices for numerous conditions, with a current major focus in pediatrics. Complementing these research areas, the DeSimone group has a third focus in Entrepreneurship, Digital Transformation, and Manufacturing.
Before joining Stanford in 2020, DeSimone was a professor of chemistry at the University of North Carolina at Chapel Hill and of chemical engineering at North Carolina State University. He is also Co-founder, Board Chair, and former CEO (2014 - 2019) of the additive manufacturing company, Carbon. DeSimone is responsible for numerous breakthroughs in his career in areas including green chemistry, medical devices, nanomedicine, and 3D printing. He has published over 350 scientific articles and is a named inventor on over 200 issued patents. Additionally, he has mentored 80 students through Ph.D. completion in his career, half of whom are women and members of underrepresented groups in STEM.
In 2016 DeSimone was recognized by President Barack Obama with the National Medal of Technology and Innovation, the highest U.S. honor for achievement and leadership in advancing technological progress. He has received numerous other major awards in his career, including the U.S. Presidential Green Chemistry Challenge Award (1997); the American Chemical Society Award for Creative Invention (2005); the Lemelson-MIT Prize (2008); the NIH Director’s Pioneer Award (2009); the AAAS Mentor Award (2010); the Heinz Award for Technology, the Economy and Employment (2017); the Wilhelm Exner Medal (2019); the EY Entrepreneur of the Year Award (2019 U.S. Overall National Winner); and the Harvey Prize in Science and Technology (2020). He is one of only 25 individuals elected to all three branches of the U.S. National Academies (Sciences, Medicine, Engineering). DeSimone received his B.S. in Chemistry in 1986 from Ursinus College and his Ph.D. in Chemistry in 1990 from Virginia Tech.
Joseph P. Donahue
Clinical Associate Professor, Orthopaedic Surgery
BioDr. Donahue is a Board Certified Orthopaedic Surgeon with Subspecialty Certification in Orthopaedic Sports Medicine. He is fellowship trained and specializes in Arthroscopic and Minimally Invasive Reconstructive Surgery of the Shoulder and Knee, and Sports Medicine.
Dr. Donahue received his undergraduate degree from Stanford University and his Doctor of Medicine from Columbia University College of Physicians and Surgeons. He completed his residency in Orthopedic Surgery at St. Luke’s-Roosevelt Hospital Center (NYC), Memorial Sloan-Kettering Cancer Center (NYC), and the Alfred I. duPont Institute (DE), and went on to a fellowship in Orthopedic Sports Medicine at the Stanford/SOAR Sports Medicine Fellowship Program.
Dr. Donahue’s interests include arthroscopic surgery of the shoulder and knee. He specializes in anterior cruciate ligament injuries, shoulder instability, and rotator cuff tears. He has done research on both shoulder instability and rotator cuff tears and has developed new techniques and medical devices for rotator cuff and all soft tissue repairs. He has started and actively serves on the medical advisory board for several surgical device companies and continues to design new surgical devices for arthroscopic procedures. He has authored several device patents and journal articles.
Dr. Donahue has been a member of the American Academy of Orthopedic Surgeons and a Diplomat of the American Board of Orthopedic Surgery. He is also member of the Arthroscopy Association of North America, the American Orthopedic Society of Sports Medicine, the California Orthopedic Association, The International Knee Society, the California Medical Association, and the Santa Clara Medical Society.
Dr. Donahue has served as the Program Director of the SOAR Orthopedic Sports Medicine Fellowship Program. He has served as the Director of Santa Clara University’s Sports Medicine Program and the Head Team Physician for all of Santa Clara University’s athletic teams, a team physician for the San Francisco 49ers, the San Francisco Giants, the Stanford Athletic Department, and many other area collegiate and high school teams.
Alfredo Dubra, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.
Lewis and Virginia Eaton Professor and Professor, by courtesy, of Education
BioMy work bridges developmental psychology, social psychology, and personality psychology, and examines the self-conceptions people use to structure the self and guide their behavior. My research looks at the origins of these self-conceptions, their role in motivation and self-regulation, and their impact on achievement and interpersonal processes.
Johannes C. Eichstaedt
Assistant Professor (Research) of Psychology
Current Research and Scholarly InterestsWell-being: affect, life satisfaction, and purpose, and their individual and societal determinants (lifestyle factors and policies); traits: character strengths, personality, trust, and empathy
Mental and physical health: depression, stress, and anxiety; health psychology: heart disease and opioid addiction
Methods: Natural Language Processing & Large Language Models; data science and
visualization; longitudinal methods, machine learning, and psychological assessment through AI
BioDr. Falisse is a postdoctoral fellow in Bioengineering working on computational approaches to study human movement disorders. He primarily uses optimization methods, biomechanical modeling, and data from various sources (wearables, videos, medical images) to get insights into movement abnormalities and design innovative treatments and rehabilitation protocols.
Dr. Falisse received his PhD from KU Leuven (Belgium) where he worked on modeling and simulating the locomotion of children with cerebral palsy. His research was supported by the Research Foundation Flanders (FWO) through a personal fellowship. Dr. Falisse received several awards for his PhD work, including the David Winter Young Investigator Award, the Andrzej J. Komor Young Investigator Award, the VPHi Thesis Award in In Silico Medicine, and the KU Leuven Research Council Award in Biomedical Sciences.
Associate Professor of Computer Science
BioKayvon Fatahalian is an Associate Professor in the Computer Science Department at Stanford University. Kayvon's research focuses on the design of systems for real-time graphics, high-efficiency simulation engines for applications in entertainment and AI, and platforms for the analysis of images and videos at scale.
Assistant Professor of Computer Science and of Electrical Engineering
BioChelsea Finn is an Assistant Professor in Computer Science and Electrical Engineering at Stanford University, and the William George and Ida Mary Hoover Faculty Fellow. Professor Finn's research interests lie in the ability to enable robots and other agents to develop broadly intelligent behavior through learning and interaction. Her work lies at the intersection of machine learning and robotic control, including topics such as end-to-end learning of visual perception and robotic manipulation skills, deep reinforcement learning of general skills from autonomously collected experience, and meta-learning algorithms that can enable fast learning of new concepts and behaviors. Professor Finn received her Bachelors degree in Electrical Engineering and Computer Science at MIT and her PhD in Computer Science at UC Berkeley. Her research has been recognized through the ACM doctoral dissertation award, an NSF graduate fellowship, a Facebook fellowship, the C.V. Ramamoorthy Distinguished Research Award, and the MIT Technology Review 35 under 35 Award, and her work has been covered by various media outlets, including the New York Times, Wired, and Bloomberg. Throughout her career, she has sought to increase the representation of underrepresented minorities within CS and AI by developing an AI outreach camp at Berkeley for underprivileged high school students, a mentoring program for underrepresented undergraduates across three universities, and leading efforts within the WiML and Berkeley WiCSE communities of women researchers.
Liu (Liao) Family Professor
Current Research and Scholarly InterestsThe microbiome carries out extraordinary feats of biology: it produces hundreds of molecules, many of which impact host physiology; modulates immune function potently and specifically; self-organizes biogeographically; and exhibits profound stability in the face of perturbations. Our lab studies the mechanisms of microbiome-host interactions. Our approach is based on two technologies we recently developed: a complex (119-member) defined gut community that serves as an analytically manageable but biologically relevant system for experimentation, and new genetic systems for common species from the microbiome. Using these systems, we investigate mechanisms at the community level and the strain level.
1) Community-level mechanisms. A typical gut microbiome consists of 200-250 bacterial species that span >6 orders of magnitude in relative abundance. As a system, these bacteria carry out extraordinary feats of metabolite consumption and production, elicit a variety of specific immune cell populations, self-organize geographically and metabolically, and exhibit profound resilience against a wide range of perturbations. Yet remarkably little is known about how the community functions as a system. We are exploring this by asking two broad questions: How do groups of organisms work together to influence immune function? What are the mechanisms that govern metabolism and ecology at the 100+ strain scale? Our goal is to learn rules that will enable us to design communities that solve specific therapeutic problems.
2) Strain-level mechanisms. Even though gut and skin colonists live in communities, individual strains can have an extraordinary impact on host biology. We focus on two broad (and partially overlapping) categories:
Immune modulation: Can we redirect colonist-specific T cells against an antigen of interest by expressing it on the surface of a bacterium? How do skin colonists induce high levels of Staphylococcus-specific antibodies in mice and humans?
Abundant microbiome-derived molecules: By constructing single-strain/single-gene knockouts in a complex defined community, we will ask: What are the effects of bacterially produced molecules on host metabolism and immunology? Can the molecular output of low-abundance organisms impact host physiology?
3) Cell and gene therapy. We have begun two new efforts in mammalian cell and gene therapies. First, we are developing methods that enable cell-type specific delivery of genome editing payloads in vivo. We are especially interested in delivery vehicles that are customizable and easy to manufacture. Second, we have begun a comprehensive genome mining effort with an emphasis on understudied or entirely novel enzyme systems with utility in mammalian genome editing.
Professor of Statistics and of Computer Science
BioEmily Fox is a Professor in the Department of Statistics and, by courtesy, Computer Science at Stanford University. Prior to Stanford, she was the Amazon Professor of Machine Learning in the Paul G. Allen School of Computer Science & Engineering and Department of Statistics at the University of Washington. From 2018-2021, Emily led the Health AI team at Apple, where she was a Distinguished Engineer. Before joining UW, Emily was an Assistant Professor at the Wharton School Department of Statistics at the University of Pennsylvania. She earned her doctorate from Electrical Engineering and Computer Science (EECS) at MIT where her thesis was recognized with EECS' Jin-Au Kong Outstanding Doctoral Thesis Prize and the Leonard J. Savage Award for Best Thesis in Applied Methodology.
Emily has been awarded a CZ Biohub Investigator Award, Presidential Early Career Award for Scientists and Engineers (PECASE), a Sloan Research Fellowship, ONR Young Investigator Award, and NSF CAREER Award. Her research interests are in large-scale Bayesian dynamic modeling, interpretability and computations, with applications in health and computational neuroscience.
Michael Fredericson, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsMy research focuses on the etiology, prevention, and treatment of overuse sports injuries in athletes and lifestyle medicine practices for improved health and longevity.
Michael T. Freehill, MD, FAOA
Associate Professor of Orthopaedic Surgery
BioDr. Freehill is a board-certified, double fellowship-trained specialist in orthopaedic surgery with a sub-specialty certification in sports medicine. His concentration is in shoulder and elbow. Dr. Freehill is a team physician for the Stanford University athletics program and head physician for the Stanford University baseball team. Dr. Freehill also teaches in the Department of Orthopaedic Surgery at Stanford University School of Medicine.
Dr. Freehill’s practice focuses on all shoulder conditions. He treats rotator cuff tears, shoulder instability, shoulder arthritis, sports shoulder, arthropathy, complex shoulder pathology, and sports related shoulder injury. In addition, he is also passionate about sports- related elbow injuries, with an emphasis on thrower’s elbow.
Professional and amateur athletes, as well as non-athletes, come to Dr. Freehill for expert care. His sports medicine training and specialization in shoulder replacement procedures enable him to treat patients across the lifespan. Depending on factors including the patient’s condition and occupation, he may recommend treatment ranging from non-operative solutions (such as physical therapy) to cutting-edge biologics procedures or complex surgery.
In addition to his positions within the Stanford University athletics program, Dr. Freehill serves as assistant team physician for the Oakland A’s. Previously, he was a team physician for the Detroit Tigers and the Winston-Salem Dash (affiliated with the Chicago White Sox); he assisted with the Baltimore Orioles. He has also served as Director of Sports Medicine for Wake Forest University Athletics.
As executive director of the Stanford Baseball Science CORE, Dr. Freehill draws on his previous experience as a professional baseball player to help athletes of all skill levels. In the lab, he conducts cutting edge research on the biomechanics of overhead throwers in order to support advances in throwing performance. He has conducted a study on pitch counts in adolescent players funded by Major League Baseball. Dr. Freehill was also awarded a research grant from the National Institutes of Health to investigate stromal vascular fractionated mesenchymal cells and their potential for healing rotator cuff tendon tears.
Dr. Freehill has pioneered the use of some of the latest techniques and technology for leading-edge care. Among the advanced technologies he utilizes is a virtual reality (VR) system that enables him to perform a simulated shoulder arthroplasty procedure prior to entering the operating room with a patient. The system also enables him to predict and order customized implants if needed, which is believed to enable a more positive outcome for patients.
Peer-reviewed articles authored by Dr. Freehill explore rotator cuff injuries, shoulder arthroplasty, baseball-related injuries and performance interests, and more. His work has been featured in the American Journal of Sports Medicine, the Orthopedic Journal of Sports Medicine, Journal of Shoulder and Elbow Surgery, Arthroscopy, and elsewhere. He has written numerous book chapters and made over 200 presentations at conferences around the world.
Dr. Freehill’s honors include an Orthopaedic Residency Research Award while at Johns Hopkins University. He is also a Neer Award winner, denoting the highest research award selected annually by the American Shoulder and Elbow Society.
Currently, he serves on the Medical Publishing Board of Trustees for the American Orthopaedic Society for Sports Medicine. He is a member of the American Orthopaedic Association, and the Major League Baseball Team Physician Association. He is a committee member for the American Shoulder and Elbow Surgeons Society, International Congress of Arthroscopy and Sports Traumatology, the Arthroscopy Association of North America, and the American Academy of Orthopaedic Surgeons.
Anne L. Friedlander
BioAnne L. Friedlander, Ph.D, is the Assistant Director of Stanford Lifestyle Medicine, an Adjunct Professor in the Program in Human Biology, and a member of the Wu Tsai Human Performance Alliance. She has served as the Director of the Exercise Physiology Lab, the Director of the Mobility Division within the Stanford Center on Longevity (SCL), and the Associate Director for Education within the Geriatric Research, Education and Clinical Center (GRECC) at the VA Palo Alto. Dr. Friedlander has broad research experience in the areas of enhancing human performance, environmental physiology, and using physical activity and mobility to promote healthy aging. She also consults regularly with companies interested in developing new products, programs and ideas in the fitness and wellness space. She is passionate about the benefits of movement on the aging process and specializes in giving talks translating scientific findings on physiology and exercise into practical applications for people.
Lawrence Fung MD PhD
Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories & Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsDr. Lawrence Fung an assistant professor in the Department of Psychiatry and Behavioral Sciences at Stanford University. He is the director of the Stanford Neurodiversity Project, director of the Neurodiversity Clinic, and principal investigator at the Fung Lab. His work, which focuses on autism and neurodiversity, traverses from multi-modal neuroimaging studies to new conceptualization of neurodiversity and its application to clinical, education, and employment settings. His lab advances the understanding of neural bases of human socio-communicative and cognitive functions by using novel neuroimaging and bioanalytical technologies. Using community-based participatory research approach, his team devises and implements novel interventions to improve the lives of neurodiverse individuals by maximizing their potential and productivity. His work has been supported by various agencies including the National Institutes of Health, Autism Speaks, California Department of Developmental Services, California Department of Rehabilitation, as well as philanthropy. He received his PhD in chemical engineering from Cornell University, and MD from George Washington University. He completed his general psychiatry residency, child and adolescent psychiatry fellowship, and postdoctoral research fellowship at Stanford.
Clinical Associate Professor (Affiliated), Psych/Public Mental Health & Population Sciences
Staff, Psych/Public Mental Health & Population Sciences
BioDr. Furst is a Clinical Associate Professor (affiliated) of Psychiatry and Behavioral Sciences and of Neurology and Neurological Sciences at Stanford University School of Medicine. He is a Principal Investigator and Director of the California War Related Illness and Injury Study Center (WRIISC) Advanced Fellowship Post-Doctoral program and Associate Director of Neuroimaging. He is also a Senior Research Scientist at the Polytrauma System of Care (PSC) at VA Palo Alto Health Care System. Dr. Furst serves as Associate Editor for the journal Frontiers in Neurology and is a member of the editorial board of NEUROLOGY. His research focuses on diagnostics and interventions related to traumatic brain injury, sleep, pain and Alzheimer's disease.
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Assistant Professor of Chemical Engineering
Current Research and Scholarly InterestsHow do we design biological systems as “smart medicine” that sense patients’ states, process the information, and respond accordingly? To realize this vision, we will tackle fundamental challenges across different levels of complexity, such as (1) protein components that minimize their crosstalk with human cells and immunogenicity, (2) biomolecular circuits that function robustly in different cells and are easy to deliver, (3) multicellular consortia that communicate through scalable channels, and (4) therapeutic modules that interface with physiological inputs/outputs. Our engineering targets include biomolecules, molecular circuits, viruses, and cells, and our approach combines quantitative experimental analysis with computational simulation. The molecular tools we build will be applied to diverse fields such as neurobiology and cancer therapy.
Rehnborg Farquhar Professor
Current Research and Scholarly InterestsThe role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines
Associate Professor of Psychology
Current Research and Scholarly InterestsHow does neural activity in the human cortex create our sense of visual perception? We use a combination of functional magnetic resonance imaging, computational modeling and analysis, and psychophysical measurements to link human perception to cortical brain activity.
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (Adult-MSD) and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly InterestsThe advent of high dimensional flow cytometry has revolutionized our ability to study and visualize the human immune system. Our group combines high parameter mass cytometry (a.k.a Cytometry by Time of Flight Mass Spectrometry, CyTOF), with advanced bio-computational methods to study how the human immune system responds and adapts to acute physiological perturbations. The laboratory currently focuses on two clinical scenarios: surgical trauma and pregnancy.
Associate Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly InterestsMy lab focuses on biomedical data fusion: the development of machine learning methods for biomedical decision support using multi-scale biomedical data. We primarily use methods based on regularized linear regression to accomplish this. We primarily focus on applications in oncology and neuroscience.
Nicholas Giori MD, PhD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsOsteoarthritis
Medical Device Development
Stanford Medicine Professor of Radiology and Biomedical Imaging
Current Research and Scholarly InterestsMy primary focus is application of new MR imaging technology to musculoskeletal problems. Current projects include: Rapid MRI for Osteoarthritis, Weight-bearing cartilage imaging with MRI, and MRI-based models of muscle. We are studying the application of new MR imaging techniques such as rapid imaging, real-time imaging, and short echo time imaging to learn more about biomechanics and pathology of bones and joints. I am also interested in functional imaging approaches using PET-MRI.
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Sleep Medicine)
BioDr. Goldstein-Piekarski directs the Computational Psychiatry, Neuroscience, and Sleep Laboratory (CoPsyN Sleep Lab) as an Assistant Professor in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine and PI within the Sierra-Pacific Mental Illness Research, Education and Clinical Center (MIRECC) at the Palo Alto VA. She received her PhD in 2014 at the University of California, Berkeley where she studied the consequences of sleep on emotional brain function. She then completed a Postdoctoral fellowship at Stanford focusing on understanding the brain basis of anxiety and depression.
As the director of the CoPsyN Sleep Lab she is developing a translational, interdisciplinary research program that combines human neuroimaging, high-density EEG sleep recording, and computational modeling to understand the neural mechanisms through which sleep disruption contributes to affective disorders, particularly depression, across the lifespan. The ultimate goals of this research are to (1) develop mechanistically-informed interventions that directly target aspects of sleep and brain function to prevent and treat affective disorders and (2) identify novel biomarkers which can identify which individuals are most likely to experience improved mood following targeted sleep interventions.
This work is currently supported by The KLS Foundation, a R01 from National Institute of Mental Health, and a R61 from the National Institute of Mental Health.
Eric R. Gross
Associate Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsA part of the laboratory studies organ injury and how common genetic variants may affect the response to injury caused by surgery; particularly aldehydes. Aldehyde accumulation can cause many post-operative complications that people experience during surgery- whether it be reperfusion injury, post-operative pain, cognitive dysfunction, or nausea. The other part of the lab studies the impact of e-cigarettes and alcohol, when coupled with genetics, on the cardiopulmonary system.
Ernest R. Hilgard Professor, Professor of Psychology and, by courtesy, of PhilosophyOn Leave from 10/01/2023 To 12/31/2023
Current Research and Scholarly InterestsI am interested in emotion and emotion regulation. My research employs behavioral, physiological, and brain measures to examine emotion-related personality processes and individual differences. My current interests include emotion coherence, specific emotion regulation strategies (reappraisal, suppression), automatic emotion regulation, and social anxiety.
Associate Professor of Psychology
BioHyowon (Hyo) Gweon (she/her) is an Associate Professor in the Department of Psychology. As a leader of the Social Learning Lab, Hyo is broadly interested in how humans learn from others and help others learn: What makes human social learning so powerful, smart, and distinctive? Taking an interdisciplinary approach that combines developmental, computational, and neuroimaging methods, her research aims to explain the cognitive underpinnings of distinctively human learning, communication, and prosocial behaviors.
Hyo received her PhD in Cognitive Science (2012) from MIT, where she continued as a post-doc before joining Stanford in 2014. She has been named as a Richard E. Guggenhime Faculty Scholar (2020) and a David Huntington Dean's Faculty Scholar (2019); she is a recipient of the APS Janet Spence Award for Transformative Early Career Contributions (2020), Jacobs Early Career Fellowship (2020), James S. McDonnell Scholar Award for Human Cognition (2018), APA Dissertation Award (2014), and Marr Prize (best student paper, Cognitive Science Society 2010).
Assistant Professor of Education and, by courtesy, of Computer Science
Current Research and Scholarly InterestsI use AI models of of exploratory and social learning in order to better understand early human learning and development, and conversely, I use our understanding of early human learning to make robust AI models that learn in exploratory and social ways. Based on this, I develop AI-powered learning tools for children, geared in particular towards the education of those with developmental issues such as the Autism Spectrum Disorder and Attention Deficit Hyperactivity Disorder, in the mold of my work on the Autism Glass Project. My formal graduate training in pure mathematics involved extending partial differential equation theory in cases involving the propagation of waves through complex media such as the space around a black hole. Since then, I have transitioned to the use of machine learning in developing both learning tools for children with developmental disorders and AI and cognitive models of learning.
Clinical Professor, Medicine - Cardiovascular Medicine
BioDr. Francois Haddad, MD is a Clinical Professor of Medicine that specializes in the field of cardio-vascular imaging, pulmonary hypertension, advanced heart failure and transplantation. Dr. Haddad has over 18 years of practice in the field of cardiology. He directs Stanford Cardiovascular Institute Biomarker and Phenotypic Core Laboratory dedicated to translational studies in cardiovascular medicine. The laboratory focuses on (1) identifying early biomarkers of heart failure and aging, (2) bioengineering approaches to cardiovascular disease modeling and (3) novel informatic approach for the detection and risk stratification of disease. He is involved is several precision medicine initiatives in health including the Project Baseline, the Integrated Personalized Omics Profiling Initiative, the Athletic screening program at Stanford and the Strong-D cardiac rehabilitation initiative in individuals with diabetes mellitus.
Professor of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology
Current Research and Scholarly Interests1. development of hospital operations centers coupled with sophisticated simulation capabilities
2. re-creation of near misses and adverse events
3. optimizing human and system performance during resuscitation
4. optimizing pattern recognition and situational awareness at the bedside
5. evaluation and optimization of debriefing
6. patient simulator design
Postdoctoral Scholar, Bioengineering
BioMy research interests lie within both sports and clinical biomechanics applications. I rely upon merging conventional biomechanical in vivo measurements together with state-of-the-art musculoskeletal modeling and optimal control simulation approaches. The integrative approach I take enables me to understand how an individual may run faster, jump further, walk following surgery or intervention, and simultaneously estimate internal body dynamics noninvasively. As a Postdoctoral Research Scholar within the Wu Tsai Human Performance Alliance I aim to explore how stochastic optimal control and reinforcement learning methods can be applied to further our understanding of sporting performance.
Brian A. Hargreaves
Professor of Radiology (Radiological Sciences Laboratory) and, by courtesy, of Electrical Engineering and of Bioengineering
Current Research and Scholarly InterestsI am interested in magnetic resonance imaging (MRI) applications and augmented reality applications in medicine. These include abdominal, breast and musculoskeletal imaging, which require development of faster, quantitative, and more efficient MRI methods that provide improved diagnostic contrast compared with current methods. My work includes novel excitation schemes, efficient imaging methods and reconstruction tools and augmented reality in medicine.
Director, Geballe Laboratory for Advanced Materials (GLAM), Professor of Materials Science and Engineering and, by courtesy, of Bioengineering and of Chemical Engineering
Current Research and Scholarly InterestsProtein engineering
H. Craig Heller
Lorry I. Lokey/Business Wire Professor
Current Research and Scholarly InterestsNeurobiology of sleep, circadian rhythms, regulation of body temperature, mammalian hibernation, and human exercise physiology. Currently applying background in sleep and circadian neurobiology the understanding and correcting the learning disability of Down Syndrome.
Jaimie Henderson, MD
John and Jene Blume - Robert and Ruth Halperin Professor, Professor of Neurosurgery and, by courtesy, of Neurology
Current Research and Scholarly InterestsMy research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; cortical physiology and its relationship to normal and pathological movement; brain-computer interfaces; and the development of novel neuromodulatory techniques for the treatment of movement disorders, epilepsy, pain, and other neurological diseases.
Executive Director, Wu Tsai Human Performance Alliance
Current Role at StanfordExecutive Director, Wu Tsai Human Performance Alliance at Stanford
Director of Research, Mobilize Center
Director of Research, Restore Center
Director Research and Development, OpenSim Project
Assistant Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)
Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).
The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders.
Professor of Bioengineering and of Microbiology and Immunology
Current Research and Scholarly InterestsHow do cells determine their shape and grow?
How do molecules inside cells get to the right place at the right time?
Our group tries to answer these questions using a systems biology approach, in which we integrate interacting networks of protein and lipids with the physical forces determined by the spatial geometry of the cell. We use theoretical and computational techniques to make predictions that we can verify experimentally using synthetic, chemical, or genetic perturbations.
Ngan F. Huang
Associate Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research) and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsDr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.
Andrew D. Huberman
Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsIn 2017, we developed a virtual reality platform to investigate the neural and autonomic mechanisms contributing to fear and anxiety. That involved capturing 360-degree videos of various fear-provoking situations in real life for in-lab VR movies, such as heights and claustrophobia, as well as unusual scenarios like swimming in open water with great white sharks. The primary objective of our VR platform is to develop new tools to help people better manage stress, anxiety and phobias in real-time, as an augment to in-clinic therapies.
In May 2018, we reported the discovery of two novel mammalian brain circuits as a Research Article published in Nature. One circuit promotes fear and anxiety-induced paralysis, while the other fosters confrontational reactions to threats. This led to ongoing research into the involvement of these brain regions in anxiety-related disorders such as phobias and generalized anxiety in humans.
In 2020, we embarked on a collaborative effort with Dr. David Spiegel's laboratory in the Stanford Department of Psychiatry and Behavioral Sciences, aimed to explore how specific respiration patterns synergize with the visual system to influence autonomic arousal and stress, and other brain states, including sleep.
In 2023, the first results of that collaboration were published as a randomized controlled trial in Cell Reports Medicine, demonstrating that specific brief patterns of deliberate respiration are particularly effective in alleviating stress and enhancing mood, and improving sleep.
In a 2021, our collaboration with Dr. Edward Chang, professor and chair of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), was published in Current Biology, revealing that specific patterns of insular cortex neural activity may be linked to, and potentially predict, anxiety responses.
Instructor, Medicine - Cardiovascular Medicine
BioDr. Ikeda is a physician-scientist who develops innovative diagnostic and therapeutic modalities for patients with cardiovascular disease. Based on his clinical experience as a cardiologist, he has become aware of major clinical shortcomings, specifically in the current pharmaceutical therapies for myocardial infarction (MI) and chronic heart failure (HF). Some evidence-based drug therapies, including β-blockers, ivabradine, and renin-angiotensin-aldosterone antagonists are difficult to apply to critical patients due to adverse side effects. Drugs that have shown efficacy in basic animal experiments have failed to show significant benefits in clinical trials. To address these problems, he moved to academia to conduct translational research. During his graduate training in the Egashira Lab, he focused on drug delivery systems (DDS) that target mitochondria in animal models of MI. He obtained advanced skills in molecular biology, mitochondrial bioenergetics, and animal surgery. He realized the importance of translational research and the great potential of DDS to overcome many clinical problems. He developed nanoparticle-mediated DDS containing cyclosporine for the treatment of patients with MI. He published a first-author paper and received academic awards for his novel science. Since becoming a postdoctoral fellow in the Yang Lab, he has continued to build upon his previous training in translational research. He is currently developing an innovative therapy, namely, extracellular vesicles-mediated mitochondrial transfer for mitochondria-related diseases such as heart failure and mitochondrial disease.