Wu Tsai Neurosciences Institute


Showing 201-300 of 555 Results

  • Scott S. Hall, Ph.D

    Scott S. Hall, Ph.D

    Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Sciences)

    Current Research and Scholarly InterestsMy primary area of scholarly and clinical interest is the pathogenesis of problem behaviors shown by individuals diagnosed with intellectual and developmental disabilities (IDD), particularly those with neurogenetic forms of IDD, such as fragile X syndrome, Cornelia de Lange syndrome and Prader-Willi syndrome. My work aims to both advance understanding of these disorders and to identify effective new treatment approaches for pediatric and adult patient populations by state-of-the-art methodologies, such as brain imaging, eye tracking and functional analysis to determine how environmental and biological factors affect the development of aberrant behaviors in these syndromes. The end goal of my research is to create patient-specific methods for treating the symptoms of these disorders.

  • Joachim Hallmayer

    Joachim Hallmayer

    Professor of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsPrincipal Investigator
    Infrastructure to facilitate discovery of autism genes
    The purpose of this project is to facilitate the discovery of the genes that contribute autism by maintaining an infrastructure which research groups studying the genetics of autism can work collaboratively. This will be
    accomplished through workshops, a Virtual Private Network, and access to a database that includes phenotype and genotype data from all participating groups.

    Principal Investigator
    A California Population-Based Twin Study of Autism
    This will address several fundamental questions: (1) What is the heritability of autism (2) What is the contribution of genetic factors to variation in symptom dimensions? (3) Is there a continuum between the quantitative neurocognitive traits and clinical disorder? (4) What proportion of the variance in the neurocognitive traits is accounted for by genetic and non-genetic factors?

    Co-Investigator
    Center for Integrating Ethics in Genetics Research(Cho)
    The goal of this project is to serve as a center of excellence in neurogenetics research, to develop a national model for bench, to bedside research ethics consultation, and to provide training opportunity in biomedical ethics.

    Co-Investigator
    Gene, Brain and Behavior in Turner Syndrome(Reiss)
    The primary objective of this project is to use advanced, multi-modal magnetic resonance imaging (MRI) techniques, analyses of X chromosome parent-of-origin and cognitive-behavioral assessment to elucidate the effects of monosomy and X-linked imprinting on neurodevelopment and neural function in a large cohort of young girls with Turner syndrome, pre-estrogen replacement.

    Project Director
    Project F: Genomic Analysis in narcolepsy cataplexy
    The goal of the project is to locate genes outside the HLA region that influence susceptibility to narcolepsy. In order to localize these genes we will carry out a linkage and association study in the most extensive world-wide collection of DNAs from well-characterized patients with narcolepsy and their families.

  • May Han, MD

    May Han, MD

    Associate Professor of Neurology (Adult Neurology)

    Current Research and Scholarly InterestsMultiple sclerosis
    Neuromyelitis optica
    Autoimmune CNS disorders

  • Antonio Hardan, M.D.

    Antonio Hardan, M.D.

    Professor of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsThe neurobiology of autism
    Neuroimaging in individuals with autism
    Psychopharmacological treatment of children and adults with autism and/or developmental disorders
    The neurobiology and innovative interventions of several neurogenic disorders including DiGeorge Syndrome (Velocardiofacial syndrome; 22q11.2 mutations), PTEN mutations, and Phelan McDermid Syndrome (22q13 mutations).

  • Keren Haroush

    Keren Haroush

    Assistant Professor of Neurobiology

    Current Research and Scholarly InterestsOur laboratory studies the mechanisms by which highly complex behaviors are mediated at the neuronal level, mainly focusing on the example of dynamic social interactions and the neural circuits that drive them. From dyadic interactions to group dynamics and collective decision making, the lab seeks a mechanistic understanding for the fundamental building blocks of societies, such as cooperation, empathy, fairness and reciprocity.

  • James Harris

    James Harris

    James and Elenor Chesebrough Professor in the School of Engineering, Emeritus

    BioHarris utilizes molecular beam epitaxy (MBE) of III-V compound semiconductor materials to investigate new materials for electronic and optoelectronic devices. He utilizes heterojunctions, superlattices, quantum wells, and three-dimensional self-assembled quantum dots to create metastable engineered materials with novel or improved properties for electronic and optoelectronic devices. His early work in the 1970's demonstrating a practical heterojunction bipolar transistor led to their application in every mobile phone today and record setting solar cell efficiency. He has recently focused on three areas: 1) integration of photonic devices and micro optics for creation of new minimally invasive bio and medical systems for micro-array and neural imaging and 2) application of nanostructures semiconductors for the acceleration of electrons using light, a dielectric Laser Accelerator (DLA), and 3) novel materials and nano structuring for high efficiency solar cells and photo electrochemical water splitting for the generation of hydrogen.

  • Trevor Hastie

    Trevor Hastie

    John A. Overdeck Professor, Professor of Statistics and of Biomedical Data Sciences

    Current Research and Scholarly InterestsFlexible statistical modeling for prediction and representation of data arising in biology, medicine, science or industry. Statistical and machine learning tools have gained importance over the years. Part of Hastie's work has been to bridge the gap between traditional statistical methodology and the achievements made in machine learning.

  • Melanie Hayden Gephart

    Melanie Hayden Gephart

    Professor of Neurosurgery and, by courtesy, of Neurology

    BioI am a brain tumor neurosurgeon, treating patients with primary and metastatic brain tumors. I treat patients with malignant and benign tumors, including glioma, brain metastases, meningioma, and vestibular schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cell free nucleic acid biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.

    www.GephartLab.com
    www.GBMseq.org
    https://stan.md/BrainMets
    @HaydenGephartMD

  • Zihuai He

    Zihuai He

    Assistant Professor (Research) of Neurology (Neurology Research Faculty), of Medicine (BMIR) and, by courtesy, of Biomedical Data Science

    Current Research and Scholarly InterestsStatistical genetics and other omics to study Alzheimer's disease.

  • Boris Heifets

    Boris Heifets

    Assistant Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD)

    Current Research and Scholarly InterestsHarnessing synaptic plasticity to treat neuropsychiatric disease

  • Jeremy J. Heit, MD, PhD

    Jeremy J. Heit, MD, PhD

    Associate Professor of Radiology (Neuroimaging and Neurointervention) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsOur research seeks to advance our understanding of cerebrovascular disease and to develop new minimally invasive treatments for these diseases. We study ischemic and hemorrhagic stroke, cerebral aneurysms, delayed cerebral ischemia, cerebral arteriovenous malformations (AVMs), dural arteriovenous fistulae, and other vascular diseases of the brain. We use state-of-the-art neuroimaging techniques to non-invasively study these diseases, and we are developing future endovascular technologies to advance neurointerventional surgery.

    www.heitlab.com

  • H. Craig Heller

    H. Craig Heller

    Lorry I. Lokey/Business Wire Professor

    Current Research and Scholarly InterestsNeurobiology of sleep, circadian rhythms, regulation of body temperature, mammalian hibernation, and human exercise physiology. Currently applying background in sleep and circadian neurobiology the understanding and correcting the learning disability of Down Syndrome.

  • Stefan Heller

    Stefan Heller

    Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor of Otolaryngology - Head & Neck Surgery (OHNS)

    Current Research and Scholarly InterestsOur research focuses on the inner ear, from its earliest manifestation as one of the cranial placodes until it has developed into a mature and functioning organ. We are interested in how the sensory epithelia of the inner ear that harbor the sensory hair cells develop, how the cells mature, and how these epithelia respond to toxic insults. The overarching goal of this research is to find ways to regenerate lost sensory hair cells in mammals.

  • Jaimie Henderson, MD

    Jaimie Henderson, MD

    John and Jene Blume - Robert and Ruth Halperin Professor, Professor of Neurosurgery and, by courtesy, of Neurology

    Current Research and Scholarly InterestsMy research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; cortical physiology and its relationship to normal and pathological movement; brain-computer interfaces; and the development of novel neuromodulatory techniques for the treatment of movement disorders, epilepsy, pain, and other neurological diseases.

  • Victor W. Henderson, MD, MS

    Victor W. Henderson, MD, MS

    Professor of Epidemiology and Population Health and of Neurology

    Current Research and Scholarly InterestsResearch interests:
    (1) Risk factors for age-associated cognitive decline and for dementia.
    (2) Therapeutic strategies to improve cognitive abilities in aging and in dementia.
    (3) Brain–behavior relations as they pertain to human cognition.

  • Tina Hernandez-Boussard

    Tina Hernandez-Boussard

    Professor of Medicine (Biomedical Informatics), of Biomedical Data Science, of Surgery and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsMy background and expertise is in the field of computational biology, with concentration in health services research. A key focus of my research is to apply novel methods and tools to large clinical datasets for hypothesis generation, comparative effectiveness research, and the evaluation of quality healthcare delivery. My research involves managing and manipulating big data, which range from administrative claims data to electronic health records, and applying novel biostatistical techniques to innovatively assess clinical and policy related research questions at the population level. This research enables us to create formal, statistically rigid, evaluations of healthcare data using unique combinations of large datasets.

  • Rogelio A. Hernández-López

    Rogelio A. Hernández-López

    Assistant Professor of Bioengineering and of Genetics

    Current Research and Scholarly InterestsOur group works at the interface of mechanistic, synthetic, and systems biology to understand and program cellular recognition, communication, and organization. We are currently interested in engineering biomedical relevant cellular behaviors for cancer immunotherapy.

  • Lambertus Hesselink

    Lambertus Hesselink

    Professor of Electrical Engineering and, by courtesy of Applied Physics

    BioHesselink's research encompasses nano-photonics, ultra high density optical data storage, nonlinear optics, optical super-resolution, materials science, three-dimensional image processing and graphics, and Internet technologies.

  • Shaul Hestrin, PhD

    Shaul Hestrin, PhD

    Professor of Comparative Medicine

    Current Research and Scholarly InterestsThe main interest of my lab is to understand how the properties of neocortical neurons, the circuits they form and the inputs they receive give rise to neuronal activity and behavior. Our approach includes behavioral studies, two-photon calcium imaging, in vivo whole cell recording in behaving animals and optogenetic methods to activate or to silence the activity of cortical neurons.

  • Karen G. Hirsch, MD

    Karen G. Hirsch, MD

    Associate Professor of Neurology (Adult Neurology)

    Current Research and Scholarly InterestsDr. Karen G. Hirsch cares for critically ill patients with neurologic disorders in the intensive care unit. Dr. Hirsch's research focuses on using continuous and discrete multi-modal data to develop phenotypes and identify signatures of treatment responsiveness in patients with coma after cardiac arrest. She is the Co-PI of PRECICECAP (PRecision Care In Cardiac ArrEst - ICECAP, NINDS R01 NS119825-01) and works closely with collaborators in data science at Stanford and with industry partners to apply machine learning analyses to the complex multi-modal ICU data. Dr. Hirsch also studies neuro-imaging in post-cardiac arrest coma and traumatic brain injury.

    Additional research interests include a broad array of topics and Dr. Hirsch greatly appreciates the importance of team science and collaboration. Along with colleagues in Biomedical Ethics, Dr. Hirsch studies brain death and organ donation with a focus on ethical challenges and prediction models. Along with colleagues in Cardiac Anesthesia and Cardiothoracic Surgery, Dr. Hirsch studies neurologic outcomes in patients on mechanical circulatory support including ECMO.

    Dr. Hirsch is broadly interested in improving neurologic outcomes after acute brain injury and identifying early phenotypes to guide precision medicine in neurocritical care, especially in patients with post-cardiac arrest brain injury.

  • Susan Holmes

    Susan Holmes

    Professor of Statistics

    Current Research and Scholarly InterestsOur lab has been developing tools for the analyses of complex data structures, extending work on multivariate data to structured multitable table that include graphs, networks and trees as well as categorical and continuous measurements.
    We created and support the Bioconductor package phyloseq for the analyses of microbial ecology data from the microbiome. We have specialized in developing interactive graphical visualization tools for doing reproducible research in biology.

  • David S. Hong

    David S. Hong

    Associate Professor of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsDr. Hong is a child and adolescent psychiatrist and clinician-scientist. His responsibilities span clinical care, teaching/mentorship, and research, with a unifying theme of advancing a developmental cognitive framework as applied to psychiatric conditions. Using this core premise, he work encompasses multiple domains: specialized clinical care, fellowship training, research mentorship, and elaborating the role of sex-specific determinants of development, one of the greatest contributors to individual developmental variation.

    His lab investigates genetic and hormonal influences underlying sex differences in child psychiatric conditions. Sex has emerged as a critical variable driving differences in the phenomenology, course, and treatment of many mental health disorders. Unfortunately, an understanding of the biological mechanisms driving these effects are limited. By applying innovative neuroimaging and multiomic approaches, Dr. Hong seeks to provide a deeper understanding of the connection between sex-specific effects and complex psychiatric diseases. To do so, research in the Hong Lab focuses on the role of genes on the X and Y chromosomes, as well as circulating sex hormones on brain development, cognition, and behavior. The lab broadly aims to elucidate the changing nature of these mechanisms across various stages of development.

    Another area of focus is the implementation of clinical informatics in child psychiatry and the development of digital mental health tools. As co-Director of the Mental Health Technology and Innovation Hub, Dr. Hong is helping to develop clinical and research infrastructure within the Department of Psychiatry and Behavioral Sciences to advance development of mobile mental health resources that will improve efficacy and access to mental health care.

  • Guosong Hong

    Guosong Hong

    Assistant Professor of Materials Science and Engineering

    BioGuosong Hong's research aims to bridge materials science and neuroscience, and blur the distinction between the living and non-living worlds by developing novel neuroengineering tools to interrogate and manipulate the brain. Specifically, the Hong lab is currently developing ultrasound, infrared, and radiofrequency-based in-vivo neural interfaces with minimal invasiveness, high spatiotemporal resolution, and cell-type specificity.

    Dr. Guosong Hong received his PhD in chemistry from Stanford University in 2014, and then carried out postdoctoral studies with at Harvard University. Dr. Hong joined Stanford Materials Science and Engineering and Neurosciences Institute as an assistant professor in 2018. He is a recipient of the NIH Pathway to Independence (K99/R00) Award, the MIT Technology Review ‘35 Innovators Under 35’ Award, the Science PINS Prize for Neuromodulation, the NSF CAREER Award, the Walter J. Gores Award for Excellence in Teaching, and the Rita Allen Foundation Scholars Award.

  • Yusuke Hori, MD

    Yusuke Hori, MD

    Clinical Instructor, Neurosurgery

    BioDr. Hori received his MD from Sapporo Medical University, Japan, and during that time he served as a Medical Student Research Fellow in the Department of Pharmacology. He explored the functional role of the SIRT1 gene, a longevity-associated gene, and its association with various conditions such as muscular dystrophy. He also completed a Visiting Student Research Fellowship at the Health Sciences University of Hokkaido and participated in Human Genetics projects focusing on an association between the 27-bp deletion and 538G>A mutation in the ABCC11 Gene.

    After graduating from medical school, Dr. Hori completed a neurosurgery residency at National Hospital Organization Okayama Medical Center in Japan. Subsequently, he completed a Stereotactic and Functional Neurosurgery Fellowship and then a Neurosurgical Oncology and Radiosurgery Fellowship at The Cleveland Clinic. He also completed an International Neurosurgery Fellowship at Boston Children's Hospital, Harvard Medical School. In 2022, he moved to Stanford University as a postdoctoral fellow, and under the supervision of Dr. Anca Pasca, he participated in brain organoid research focusing on hypoxic brain injuries.

    Since July 2023, Dr. Hori has been working as a Clinical Instructor (Neurosurgical Oncology and Radiosurgery) in the Department of Neurosurgery at Stanford under the supervision of Dr. Steven D. Chang. His clinical interests include malignant brain and spine tumors in both adult and pediatric patients. His clinical research focuses on the application of minimally invasive treatments such as laser interstitial thermal therapy, focused ultrasound, and radiosurgery to treat various neurosurgical conditions. His current lab research aims to develop an organoid model for radiation-induced brain injuries and a high-throughput screening platform to identify novel therapeutic compounds, for which he received a Clinician Educator Grant from Stanford University Maternal and Child Health Research Institute. Outside of medicine, he enjoys playing music including guitar and drums.

  • Mark Horowitz

    Mark Horowitz

    Fortinet Founders Chair of the Department of Electrical Engineering , Yahoo! Founders Professor in the School of Engineering and Professor of Computer Science

    BioProfessor Horowitz initially focused on designing high-performance digital systems by combining work in computer-aided design tools, circuit design, and system architecture. During this time, he built a number of early RISC microprocessors, and contributed to the design of early distributed shared memory multiprocessors. In 1990, Dr. Horowitz took leave from Stanford to help start Rambus Inc., a company designing high-bandwidth memory interface technology. After returning in 1991, his research group pioneered many innovations in high-speed link design, and many of today’s high speed link designs are designed by his former students or colleagues from Rambus.

    In the 2000s he started a long collaboration with Prof. Levoy on computational photography, which included work that led to the Lytro camera, whose photographs could be refocused after they were captured.. Dr. Horowitz's current research interests are quite broad and span using EE and CS analysis methods to problems in neuro and molecular biology to creating new agile design methodologies for analog and digital VLSI circuits. He remains interested in learning new things, and building interdisciplinary teams.

  • Hadi Hosseini

    Hadi Hosseini

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Interdisciplinary Brain Science Research)

    Current Research and Scholarly InterestsOur lab’s research portfolio crosses multiple disciplines including computational neuropsychiatry, cognitive neuroscience, multimodal neuroimaging and neurocognitive rehabilitation. Our computational neuropsychiatry research mainly involves investigating alterations in the organization of connectome in various neurodevelopmental and neurocognitive disorders using state of the art neuroimaging techniques (fMRI, sMRI, DWI, functional NIRS) combined with novel computational methods (graph theoretical and multivariate pattern analyses).

    The ultimate goal of our research is to translate the findings from computational neuropsychiatry research toward developing personalized interventions. We have been developing personalized interventions that integrate computerized cognitive rehabilitation, real-time functional brain imaging and neurofeedback, as well as virtual reality (VR) tailored toward targeted rehabilitation of the affected brain networks in patients with neurocognitive disorders.

  • Roger Howe

    Roger Howe

    William E. Ayer Professor of Electrical Engineering, Emeritus

    BioDesign and fabrication of sensors and actuators using micro and nanotechnologies, with applications to information processing and energy conversion.

  • Yang Hu, MD, PhD

    Yang Hu, MD, PhD

    Associate Professor of Ophthalmology

    Current Research and Scholarly InterestsThe ultimate goal of the laboratory is to develop efficient therapeutic strategies to achieve CNS neural repair, through promoting neuroprotection, axon regeneration and functional recovery.

    More specifically, we study retinal ganglion cell (RGC) and optic nerve in various optic neuropathies including traumatic, glaucomatous and inflammatory optic nerve injuries to fully understand the molecular mechanisms of CNS neurodegeneration and axon regeneration failure.

  • Ting-Ting Huang

    Ting-Ting Huang

    Associate Professor (Research) of Neurology (Adult Neurology)

    Current Research and Scholarly InterestsWe study the role of oxygen free radicals in oxidative tissue damage and degeneration. Our research tools include transgenic and knockout mice and tissue culture cells for in vitro gene expression.

  • Andrew D. Huberman

    Andrew D. Huberman

    Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsIn 2017, we developed a virtual reality platform to investigate the neural and autonomic mechanisms contributing to fear and anxiety. That involved capturing 360-degree videos of various fear-provoking situations in real life for in-lab VR movies, such as heights and claustrophobia, as well as unusual scenarios like swimming in open water with great white sharks. The primary objective of our VR platform is to develop new tools to help people better manage stress, anxiety and phobias in real-time, as an augment to in-clinic therapies.

    In May 2018, we reported the discovery of two novel mammalian brain circuits as a Research Article published in Nature. One circuit promotes fear and anxiety-induced paralysis, while the other fosters confrontational reactions to threats. This led to ongoing research into the involvement of these brain regions in anxiety-related disorders such as phobias and generalized anxiety in humans.

    In 2020, we embarked on a collaborative effort with Dr. David Spiegel's laboratory in the Stanford Department of Psychiatry and Behavioral Sciences, aimed to explore how specific respiration patterns synergize with the visual system to influence autonomic arousal and stress, and other brain states, including sleep.

    In 2023, the first results of that collaboration were published as a randomized controlled trial in Cell Reports Medicine, demonstrating that specific brief patterns of deliberate respiration are particularly effective in alleviating stress and enhancing mood, and improving sleep.

    In a 2021, our collaboration with Dr. Edward Chang, professor and chair of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), was published in Current Biology, revealing that specific patterns of insular cortex neural activity may be linked to, and potentially predict, anxiety responses.

  • John Huguenard

    John Huguenard

    Professor of Neurology (Neurology Research Faculty), of Neurosurgery (Adult Neurosurgery) and, by courtesy, of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsWe are interested in the neuronal mechanisms that underlie synchronous oscillatory activity in the thalamus, cortex and the massively interconnected thalamocortical system. Such oscillations are related to cognitive processes, normal sleep activities and certain forms of epilepsy. Our approach is an analysis of the discrete components (cells, synapses, microcircuits) that make up thalamic and cortical circuits, and reconstitution of components into in silico computational networks.

  • Keith Humphreys

    Keith Humphreys

    Esther Ting Memorial Professor

    Current Research and Scholarly InterestsDr. Humphreys researches individual and societal level interventions for addictive and psychiatric disorders. He focuses particularly on evaluating the outcomes of professionally-administered treatments and peer-operated self-help groups (e.g., Alcoholics Anonymous), and, analyzing the impact of public policies touching addiction, mental health, public health, and public safety.

  • Ruth Huttenhain

    Ruth Huttenhain

    Assistant Professor of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsMy group deciphers how G protein-coupled receptors decode extracellular cues into dynamic and context-specific cellular signaling networks to elicit diverse physiologic responses. We exploit quantitative proteomics to capture the spatiotemporal organization of signaling networks combined with functional genomics to study their impact on physiology.

  • Robert K. Jackler, MD

    Robert K. Jackler, MD

    Edward C. and Amy H. Sewall Professor, Emeritus

    Current Research and Scholarly InterestsSince the early 2000s, study of tobacco industry marketing has become my primary field of research. Motivated by the lack of a comprehensive and well-organized compendium of tobacco advertisements, and the relative paucity of scholarly research analyzing the marketing practices of the industry, I chose to focus my research on advertising. The overarching purpose of my research has been to reveal the behavior of the tobacco industry in recruiting and retaining its consumers with the goal of infor

  • Siddhartha Jaiswal

    Siddhartha Jaiswal

    Assistant Professor of Pathology

    Current Research and Scholarly InterestsWe identified a common disorder of aging called clonal hematopoiesis of indeterminate potential (CHIP). CHIP occurs due to certain somatic mutations in blood stem cells and represents a precursor state for blood cancer, but is also associated with increased risk of cardiovascular disease and death. We hope to understand more about the biology and clinical implications of CHIP using human and model system studies.

  • Daniel Jarosz

    Daniel Jarosz

    Associate Professor of Chemical and Systems Biology and of Developmental Biology

    Current Research and Scholarly InterestsMy laboratory studies conformational switches in evolution, disease, and development. We focus on how molecular chaperones, proteins that help other biomolecules to fold, affect the phenotypic output of genetic variation. To do so we combine classical biochemistry and genetics with systems-level approaches. Ultimately we seek to understand how homeostatic mechanisms influence the acquisition of biological novelty and identify means of manipulating them for therapeutic and biosynthetic benefit.

  • Julia Kaltschmidt

    Julia Kaltschmidt

    Associate Professor of Neurosurgery

    Current Research and Scholarly InterestsThe lab’s primary research interest is to understand how specific neuronal circuits are established. We use mouse genetics, combinatorial immunochemical labeling and high-resolution laser scanning microscopy to identify, manipulate, and quantitatively analyze synaptic contacts within the complex neuronal milieu of the spinal cord and the enteric nervous system.

  • Makoto Kawai

    Makoto Kawai

    Clinical Associate Professor, Psychiatry and Behavioral Sciences - Sleep Medicine

    BioI am a physician scientist in the field of sleep medicine in aging and brain function. Using combined polysomnogram and novel neuroimaging technology, I aim to identify potential sleep biomarkers to investigate the mechanism of progression from normal aging to Mild Cognitive Impairment (MCI) or dementia. I also investigate the impact of sleep on cognitive/affective function or behavior abnormality in various neurodevelopmental and neurodegenerative disorders.

  • Mark A. Kay, M.D., Ph.D.

    Mark A. Kay, M.D., Ph.D.

    Dennis Farrey Family Professor of Pediatrics, and Professor of Genetics

    Current Research and Scholarly InterestsMark A. Kay, M.D., Ph.D. Director of the Program in Human Gene Therapy and Professor in the Departments of Pediatrics and Genetics. Respected worldwide for his work in gene therapy for hemophilia, Dr. Kay and his laboratory focus on establishing the scientific principles and developing the technologies needed for achieving persistent and therapeutic levels of gene expression in vivo. The major disease models are hemophilia, hepatitis C, and hepatitis B viral infections.

  • Corey Keller, MD, PhD

    Corey Keller, MD, PhD

    Assistant Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)

    Current Research and Scholarly InterestsThe goal of my lab is to understand the fundamental principles of human brain plasticity and build trans-diagnostic real-time monitoring platforms for personalized neurotherapeutics.

    We use an array of neuroscience methods to better understand the basic principles of how to create change in brain circuits. We use this knowledge to develop more effective treatment strategies for depression and other psychiatric disorders.

  • Oussama Khatib

    Oussama Khatib

    Weichai Professor and Professor, by courtesy, of Electrical Engineering

    BioRobotics research on novel control architectures, algorithms, sensing, and human-friendly designs for advanced capabilities in complex environments. With a focus on enabling robots to interact cooperatively and safely with humans and the physical world, these studies bring understanding of human movements for therapy, athletic training, and performance enhancement. Our work on understanding human cognitive task representation and physical skills is enabling transfer for increased robot autonomy. With these core capabilities, we are exploring applications in healthcare and wellness, industry and service, farms and smart cities, and dangerous and unreachable settings -- deep in oceans, mines, and space.

  • Chaitan Khosla

    Chaitan Khosla

    Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry

    Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.

    For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.

    For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine.

  • Butrus Khuri-Yakub

    Butrus Khuri-Yakub

    Professor (Research) of Electrical Engineering, Emeritus

    BioButrus (Pierre) T. Khuri-Yakub is a Professor of Electrical Engineering at Stanford University. He received the BS degree from the American University of Beirut, the MS degree from Dartmouth College, and the Ph.D. degree from Stanford University, all in electrical engineering. His current research interests include medical ultrasound imaging and therapy, ultrasound neuro-stimulation, chemical/biological sensors, gas flow and energy flow sensing, micromachined ultrasonic transducers, and ultrasonic fluid ejectors. He has authored over 600 publications and has been principal inventor or co-inventor of 107 US and international issued patents. He was awarded the Medal of the City of Bordeaux in 1983 for his contributions to Nondestructive Evaluation, the Distinguished Advisor Award of the School of Engineering at Stanford University in 1987, the Distinguished Lecturer Award of the IEEE UFFC society in 1999, a Stanford University Outstanding Inventor Award in 2004, Distinguished Alumnus Award of the School of Engineering of the American University of Beirut in 2005, Stanford Biodesign Certificate of Appreciation for commitment to educate, mentor and inspire Biodesgin Fellows, 2011, and 2011 recipient of IEEE Rayleigh award.

  • Mathew Kiang

    Mathew Kiang

    Assistant Professor of Epidemiology and Population Health (Epidemiology)

    BioI am an assistant professor in the Department of Epidemiology and Population Health. My research lies at the intersection of computational epidemiology and social epidemiology. Methodologically, my work revolves around combining disparate data sources in epidemiologically meaningful ways. For example, I work with individual-level, non-health data (e.g., GPS, accelerometer, and other sensor data from smartphones), traditional health data (e.g., survey, health systems, or death certificate data), and third-party data (e.g., cellphone providers or ad-tech data). To do this, I use a variety of methods such as joint Bayesian spatial models, traditional epidemiologic models, dynamical models, microsimulation, and demographic analysis. Substantively, my work focuses on socioeconomic and racial/ethnic inequities. For example, recently, my work has examined inequities in COVID-19 vaccine distribution, cause-specific excess mortality, and drug poisonings. I have an NIDA-funded R00 examining equitable ways to improve treatment for opioid use disorder across structurally disadvantaged groups and am Co-I on a NIDA-funded R21 examining ways to use novel data sources (such as social media) to predict surges in opioid-related mortality.

  • Peter S. Kim

    Peter S. Kim

    Virginia and D. K. Ludwig Professor of Biochemistry
    On Partial Leave from 09/01/2023 To 06/30/2024

    Current Research and Scholarly InterestsWe are studying the mechanism of viral membrane fusion and its inhibition by drugs and antibodies. We use the HIV envelope protein (gp120/gp41) as a model system. Some of our studies are aimed at creating an HIV vaccine. We are also characterizing protein surfaces that are referred to as "non-druggable". These surfaces are defined empirically based on failure to identify small, drug-like molecules that bind to them with high affinity and specificity.

  • Seung K. Kim  M.D., Ph.D.

    Seung K. Kim M.D., Ph.D.

    KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)

    Current Research and Scholarly InterestsWe study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.

  • David Kingsley

    David Kingsley

    Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine

    Current Research and Scholarly InterestsWe use mice, stickleback fish, and humans to study the molecular basis of evolution and common diseases. By combining genetics and genomics, we have identified key DNA changes that control bone formation, limb patterning, hair color, brain evolution, and susceptibility to arthritis, schizophrenia, and bipolar disorder. We find that the same genetic mechanisms are often used repeatedly in nature, providing new insights into the origin of key traits in many different species, including ourselves.

  • Eric I. Knudsen

    Eric I. Knudsen

    Edward C. and Amy H. Sewall Professor in the School of Medicine, Emeritus

    Current Research and Scholarly InterestsCellular mechanisms of spatial attention and learning, studied in the central nervous system in birds, using behavioral, systems, cellular and molecular techniques.

  • Brian Knutson

    Brian Knutson

    Professor of Psychology

    Current Research and Scholarly InterestsMy lab and I seek to elucidate the neural basis of emotion (affective neuroscience), and explore implications for decision-making (neuroeconomics) and psychopathology (neurophenomics).

  • Brian Kobilka

    Brian Kobilka

    Hélène Irwin Fagan Chair of Cardiology

    Current Research and Scholarly InterestsStructure, function and physiology of adrenergic receptors.

  • Mykel Kochenderfer

    Mykel Kochenderfer

    Associate Professor of Aeronautics and Astronautics and, by courtesy, of Computer Science

    BioMykel Kochenderfer is Associate Professor of Aeronautics and Astronautics at Stanford University. Prior to joining the faculty, he was at MIT Lincoln Laboratory where he worked on airspace modeling and aircraft collision avoidance, with his early work leading to the establishment of the ACAS X program. He received a Ph.D. from the University of Edinburgh and B.S. and M.S. degrees in computer science from Stanford University. Prof. Kochenderfer is the director of the Stanford Intelligent Systems Laboratory (SISL), conducting research on advanced algorithms and analytical methods for the design of robust decision making systems. Of particular interest are systems for air traffic control, unmanned aircraft, and other aerospace applications where decisions must be made in uncertain, dynamic environments while maintaining safety and efficiency. Research at SISL focuses on efficient computational methods for deriving optimal decision strategies from high-dimensional, probabilistic problem representations. He is an author of "Decision Making under Uncertainty: Theory and Application" (2015), "Algorithms for Optimization" (2019), and "Algorithms for Decision Making" (2022), all from MIT Press. He is a third generation pilot.

  • Eric Kool

    Eric Kool

    George A. and Hilda M. Daubert Professor of Chemistry

    Current Research and Scholarly Interests• Design of cell-permeable reagents for profiling, modifying, and controlling RNAs
    • Developing fluorescent probes of DNA repair pathways, with applications in cancer, aging, and neurodegenerative disease
    • Discovery and development of small-molecule modulators of DNA repair enzymes, with focus on cancer and inflammation

  • Ron Kopito

    Ron Kopito

    Professor of Biology

    Current Research and Scholarly InterestsOur laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.

  • Lorrin Koran

    Lorrin Koran

    Professor (Clinical) of Psychiatry and Behavioral Sciences, Emeritus

    Current Research and Scholarly Interestsobsessive-compulsive disorder, depressive disorders, psychopharmacology, cost-effectiveness studies, trichotillomania, compulsive buying, pathological gambling,kleptomania.

  • Andrea Lora Kossler, MD, FACS

    Andrea Lora Kossler, MD, FACS

    Assoc Professor of Ophthalmology

    Current Research and Scholarly InterestsThyroid Eye Disease
    Adenoid Cystic Carcinoma of the Lacrimal Gland
    Lacrimal Gland Stimulation for the Treatment of Dry Eyes
    Neurostimulation
    Orbital Tumors
    Floppy Eyelid Syndrome and Obstructive Sleep Apnea

  • Gregory Kovacs

    Gregory Kovacs

    Professor of Electrical Engineering, Emeritus

    Current Research and Scholarly InterestsHis present research areas include instruments for biomedical and biological applications including space flight, solid-state sensors and actuators, cell-based sensors for toxin detection and pharmaceutical screening, microfluidics, electronic interfaces to tissue, and biotechnology, all with emphasis on solving practical problems.

  • Elizabeth Bailey Kozleski

    Elizabeth Bailey Kozleski

    Professor (Research) of Education

    BioI engage in systems change and research on equity and justice issues in inclusive education in schools, school systems as well as state and national education organizations and agencies. My research interests include the analysis of systems change in education, how teachers learn in practice in complex, diverse school settings, including how educational practices improve student learning. Awards include the 2023 Luminary Award from the Division of Culturally and Linguistically Diverse Exceptional Children, Council of Exceptional Children; the 2018 Budig Award for Teaching Excellence in Special Education at the University of Kansas; the 2017 Boeing-Allan Visiting Endowed Chair at Seattle University; the University of Kansas 2016 Woman of Distinction award; the 2013 Scholar of the Century award from the University of Northern Colorado; the 2011 TED-Merrill award for leadership in special education teacher education in 2011; and the UNESCO Chair in Inclusive International Research. I co-lead the World Education Research Association International Research Network on Student Voice for Promoting Equity and Inclusion in Schools along with Professor Kyriaki Messiou of the University of South Hampton, UK.

    A number of my articles focus on the design and development of teacher education programs that involve extensive clinical practice in general education settings. I have led the development of such programs in three universities, and continue to do research and development work in teacher education. I have also offered technical assistance as well as conducted research on the impact of technical assistance on individuals, as well as local, state, and national systems in the U.S. and abroad.

    I have received funding for more than $35 million in federal, state, and local grants. I serve on the Board of Editors for the book series Inclusive Education and Partnerships, an international book series produced by Deep University. Recent books include Ability, Equity, and Culture (with co-author Kathleen King Thorius) published by Teachers College Press in ‘14 and Equity on Five Continents (with Alfredo Artiles and Federico Waitoller) published in ‘11 by Harvard Education Press.

  • Mark Krasnow

    Mark Krasnow

    Paul and Mildred Berg Professor

    Current Research and Scholarly Interests- Lung development and stem cells
    - Neural circuits of breathing and speaking
    - Lung diseases including lung cancer
    - New genetic model organism for biology, behavior, health and conservation

  • Ellen Kuhl

    Ellen Kuhl

    Walter B Reinhold Professor in the School of Engineering, Robert Bosch Chair of Mechanical Engineering, Professor of Mechanical Engineering and, by courtesy, of Bioengineering

    Current Research and Scholarly Interestscomputaitonal simulation of brain development, cortical folding, computational simulation of cardiac disease, heart failure, left ventricular remodeling, electrophysiology, excitation-contraction coupling, computer-guided surgical planning, patient-specific simulation

  • Anshul Kundaje

    Anshul Kundaje

    Associate Professor of Genetics and of Computer Science

    Current Research and Scholarly InterestsWe develop statistical and machine learning frameworks to learn predictive, dynamic and causal models of gene regulation from heterogeneous functional genomics data.

  • Calvin Kuo

    Calvin Kuo

    Maureen Lyles D'Ambrogio Professor

    Current Research and Scholarly InterestsWe study cancer biology, intestinal stem cells (ISC), and angiogenesis. We use primary organoid cultures of diverse tissues and tumor biopsies for immunotherapy modeling, oncogene functional screening and stem cell biology. Angiogenesis projects include blood-brain barrier regulation, stroke therapeutics and anti-angiogenic cancer therapy. ISC projects apply organoid culture and ko mice to injury-inducible vs homeostatic stem cells and symmetric division mechanisms.

  • Clete A. Kushida, MD, PhD

    Clete A. Kushida, MD, PhD

    Professor of Psychiatry and Behavioral Sciences (Sleep Medicine)

    Current Research and Scholarly InterestsDr. Kushida is a neurologist and sleep specialist who directs several NIH- and industry-sponsored research studies, focused on topics such as the physical features and neurocognitive changes associated with the obstructive sleep apnea syndrome, the epidemiology and treatment of restless legs syndrome/periodic limb movement disorder, primary care sleep education and training, and countermeasures for sleep loss.

  • Tze Leung Lai

    Tze Leung Lai

    Member, Wu Tsai Neurosciences Institute

    Current Research and Scholarly InterestsResearch interests include clinical trial design, cancer biostatistics, survival analysis, adaptation and sequential experimentation, change-point detection and segmentation, stochastic optimization, time series and inference on stochastic processes, hidden Markov models and genomic applications.

  • Scott R. Lambert, MD

    Scott R. Lambert, MD

    Professor of Ophthalmology and, by courtesy, of Pediatrics

    Current Research and Scholarly InterestsMy research has focused on improving the visual outcomes of children with congenital cataracts. I organized a randomized clinical trial, the Infant Aphakia Treatment Study to compare the visual outcomes of infants optically corrected with a contact lens vs. an intraocular lens after unilateral cataract surgery. A second area of research has been ocular growth after cataract surgery.

  • James Landay

    James Landay

    Denning Co-Director (Acting) of Stanford HAI, Anand Rajaraman and Venky Harinarayan Professor and Senior Fellow at the Stanford Institute for HAI

    Current Research and Scholarly InterestsLanday's current research interests include Technology to Support Behavior Change (especially for health and sustainability), Demonstrational User Interfaces, Mobile & Ubiquitous Computing, Cross-Cultural Interface Design, Human-Centered AI, and User Interface Design Tools. He has developed tools, techniques, and a top professional book on Web Interface Design.

  • Joshua Landy

    Joshua Landy

    Andrew B. Hammond Professor of French Language, Literature and Civilization, and Professor of Comparative Literature and, by courtesy, of English

    BioJoshua Landy is the Andrew B. Hammond Professor of French, Professor of Comparative Literature, and co-director of the Literature and Philosophy Initiative at Stanford, home to a PhD minor and undergraduate major tracks in Philosophy and Literature.

    Professor Landy is the author of Philosophy as Fiction: Self, Deception, and Knowledge in Proust (Oxford, 2004) and of How To Do Things with Fictions (Oxford, 2012). He is also the co-editor of two volumes, Thematics: New Approaches (SUNY, 1995, with Claude Bremond and Thomas Pavel) and The Re-Enchantment of the World: Secular Magic in a Rational Age (Stanford, 2009, with Michael Saler). Philosophy as Fiction deals with issues of self-knowledge, self-deception, and self-fashioning in Proust's A la recherche du temps perdu, while raising the question of what literary form contributes to an engagement with such questions; How to Do Things with Fictions explores a series of texts (by Plato, Beckett, Mallarmé, and Mark) that function as training-grounds for the mental capacities.

    Professor Landy has appeared on the NPR shows "Forum" and "Philosophy Talk" (on narrative selfhood and on the function of fiction) and has on various occasions been a guest host of Robert Harrison's "Entitled Opinions" (with Lera Boroditsky on Language and Thought, with Michael Saler on Re-Enchantment, with John Perry and Ken Taylor on the Uses of Philosophy, and with Alexander Nehamas on Beauty).

    Professor Landy has received the Walter J. Gores Award for Teaching Excellence (1999) and the Dean's Award for Distinguished Teaching (2001).

  • Maarten Lansberg, MD, PhD

    Maarten Lansberg, MD, PhD

    Professor of Neurology (Adult Neurology) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsMy research involves the design and conduct of clinical trials to discover new treatments for patients who have suffered a stroke. These trials span treatment of acute stroke, stroke recovery, and stroke prevention. My research in acute stroke is primarily focused on the use of advanced neuroimaging methods (CT and MRI) to select patients who are most likely to benefit from therapies aimed at restoring blood flow to the brain in patients who have suffered a stroke.

  • Jennifer Lee

    Jennifer Lee

    Professor of Medicine (Endocrinology) and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsI am a clinical scientist (PhD epidemiology), endocrinologist, and CMO at VAPA Cooperative Studies Program Coordinating Center. My group does pattern and prediction mapping along the life-course of interventions/outcomes and how healthcare system can positively impact health longitudinally. We use novel molecular epi, 'big' data like EHRs using multiple designs/methods/technologies. These interests cut across multiple complex chronic diseases and lifespan.
    https://med.stanford.edu/jleelab.html

  • Larry John Leifer

    Larry John Leifer

    Professor of Mechanical Engineering, Emeritus

    Current Research and Scholarly InterestsOur "designXlab" at the Stanford Center for Design Research (CDR) has long (30+ years) been focused on Engineering Design Team dynamics at global collaboration scale working with corporate partners in my graduate course ME310ABC. In our most recent studies we have added Neuroscience visualization of brain activity using fMRI and fNIRS. In doing so we have launched "NeuroDesign" as a professional discipline.

  • John Leikauf

    John Leikauf

    Clinical Associate Professor, Psychiatry and Behavioral Sciences - Child & Adolescent Psychiatry and Child Development

    Current Research and Scholarly InterestsI am interested in better understanding the heterogeneous cognitive and electrophysiological abnormalities in children with ADHD and the many other conditions that commonly co-occur with ADHD. The long-term goal is to be able to better target treatments to specific deficits in order to promote long-term health and well-being and improve outcomes that matter to individuals and families suffering from these disorders.

  • Theodore Leng, MD, FACS

    Theodore Leng, MD, FACS

    Associate Professor of Ophthalmology and, by courtesy, of Anesthesiology, Perioperative and Pain Medicine (Adult MSD)

    Current Research and Scholarly InterestsDr. Leng was the first surgeon in California to perform a subretinal transplant of adult neural stem cells into patients with macular degeneration and is actively researching cellular, biologic and laser-based therapies for macular degeneration. He also has an active program in imaging informatics and deep learning to perform big data analyses of retinal scans to identify patients who are at risk for retinal disease deterioration. The end goal is earlier detection and rapid treatment to maximize visual outcomes.

    Dr. Leng is considered a leading expert on optical coherence tomography (OCT) and OCT-based angiography (OCTA), a non-invasive and non-contact imaging technique for the retina. He is also considered a key opinion leader in artificial intelligence and data science.

  • Jure Leskovec

    Jure Leskovec

    Professor of Computer Science

    BioJure Leskovec is Professor of Computer Science at Stanford University. He is affiliated with the Stanford AI Lab, Machine Learning Group and the Center for Research on Foundation Models. In the past, he served as a Chief Scientist at Pinterest and was an investigator at Chan Zuckerberg BioHub. Leskovec recently pioneered the field of Graph Neural Networks and co-authored PyG, the most widely-used graph neural network library. Research from his group has been used by many countries to fight COVID-19 pandemic, and has been incorporated into products at Facebook, Pinterest, Uber, YouTube, Amazon, and more.

    His research received several awards including Microsoft Research Faculty Fellowship in 2011, Okawa Research award in 2012, Alfred P. Sloan Fellowship in 2012, Lagrange Prize in 2015, and ICDM Research Contributions Award in 2019. His research contributions have spanned social networks, data mining and machine learning, and computational biomedicine with the focus on drug discovery. His work has won 12 best paper awards and 5 10-year test of time awards at a premier venues in these research areas.

    Leskovec received his bachelor's degree in computer science from University of Ljubljana, Slovenia, PhD in machine learning from Carnegie Mellon University and postdoctoral training at Cornell University.

  • Douglas F. Levinson, M.D.

    Douglas F. Levinson, M.D.

    Walter E. Nichols, M.D. Professor in the School of Medicine, Emeritus

    Current Research and Scholarly InterestsDr. Levinson directs the Program on the Genetics of Brain Function in the Department of Psychiatry and Behavioral Sciences. The program investigates the genetic basis of psychiatric disorders (schizophrenia and major depressive disorder), using genetic association, linkage and resequencing methodologies. In collaboration with Dr. Alice Whittemore, we are also actively engaged in statistical methods testing and development for genetic research.

  • Michael Levitt

    Michael Levitt

    Robert W. and Vivian K. Cahill Professor of Cancer Research

    Current Research and Scholarly InterestsStanford Professor of Biophysics and Computational Biology, Cambridge PhD and DSc, 2013 Chemistry Nobel Laureate (complex systems), FRS & US National Academy member, I code well for my age.

  • Richard Lewis

    Richard Lewis

    Professor of Molecular and Cellular Physiology, Emeritus

    Current Research and Scholarly InterestsWe study molecular mechanisms of calcium signaling with a focus on store-operated CRAC channels and their essential roles in T cell development and function. Currently we aim to define the molecular mechanism for CRAC channel activation and the means by which calcium signal dynamics mediate specific activation of transcription factors and T-cell genes during development.

  • Gordon Li, MD

    Gordon Li, MD

    Professor of Neurosurgery and, by courtesy, of Neurology and of Otolaryngology - Head & Neck Surgery (OHNS)

    Current Research and Scholarly Interests1.) My laboratory studies the biology of brain tumors with the goal of developing novel therapeutics for the treatment of malignant brain tumors and translating that research into clinical trials.
    2.) My clinical interests include improving surgical techniques for brain tumor surgery, immunotherapy for the treatment of glioblastoma, and novel uses for stereotactic radiosurgery.

  • Jin Billy Li

    Jin Billy Li

    Professor of Genetics

    Current Research and Scholarly InterestsThe Li Lab is primarily interested in RNA editing mediated by ADAR enzymes. We co-discovered that the major function of RNA editing is to label endogenous dsRNAs as "self" to avoid being recognized as "non-self" by MDA5, a host innate immune dsRNA sensor, leading us to pursue therapeutic applications in cancer, autoimmune diseases, and viral infection. The other major direction of the lab is to develop technologies to harness endogenous ADAR enzymes for site-specific transcriptome engineering.

  • Yi Li, MD, PhD

    Yi Li, MD, PhD

    Clinical Assistant Professor, Neurology & Neurological Sciences

    BioDr. Li is a board-certified, fellowship-trained neurologist and a clinical assistant professor in the Department of Neurology and Neurological Sciences at Stanford University School of Medicine.

    She specializes in epilepsy care and research. She has dedicated her career to advancing our understanding of the mechanism, diagnosis, and treatment of epilepsy. In addition to her MD degree, she holds a PhD degree in neurology and neuroscience. She undertook PhD training to better understand epileptogenesis and to identify potential new treatments for refractory epilepsy patients. She has received the Stanford Genetics and Genomics Certificate, which helped advance her knowledge of how genomic data can enhance patient management in clinical practice.

    She has published numerous articles on a wide range of epilepsy-related topics. Among her honors, Dr. Li has earned recognition from the American Epilepsy Society and International League Against Epilepsy. She also won a safety and quality awards scholarship from the American Academy of Neurology. She is a member of the American Academy of Neurology and the American Epilepsy Society.

  • Y. Joyce Liao, MD, PhD

    Y. Joyce Liao, MD, PhD

    Stanford Medicine Professor of Ophthalmology and Professor of Neurology

    Current Research and Scholarly InterestsIschemic optic neuropathy
    Stem cell transplantation
    Optic neuropathy
    Optic neuritis
    Eye movement disorders
    Reading
    Parkinson's disease
    Multiple sclerosis

  • Michael Lim, M.D.

    Michael Lim, M.D.

    Professor of Neurosurgery and, by courtesy, of Radiation Oncology (Radiation Therapy), of Medicine (Oncology), of Otolaryngology - Head & Neck Surgery (OHNS) and of Neurology

    BioDr. Lim is the Chair of the Department of Neurosurgery and a board-certified neurosurgeon specializing in brain tumors and trigeminal neuralgia.

    Dr. Lim’s clinical interests include the treatment of benign and malignant brain tumors, with special interest in gliomas, meningiomas, metastatic tumors, and skull base tumors. Dr. Lim also specializes in surgical treatments for trigeminal neuralgia. During his time at Johns Hopkins, Dr. Lim built one of the largest brain tumor and trigeminal neuralgia practices and utilized the most advanced surgical technologies and techniques for his patients. As a passionate voice for patient experience, he has been recognized by his peers and patients for his integrity and compassionate care, including a Service Excellence Award from HealthNetwork Foundation.

    As a mentor, he has garnered numerous teaching awards, including being honored as an outstanding teacher by Johns Hopkins University School of Medicine. He is actively involved in shaping education for neurosurgery and oncology across the United States and around the world. He is the recipient of the prestigious 2023 Abhijit Guha Award in Neuro-Oncology.

    Dr. Lim’s research interests focus on harnessing the immune system to fight cancer. His laboratory focuses on understanding mechanisms of immune evasion by cancer cells. He has successfully translated his findings from the laboratory to the clinics and has conducted and led several large national immunotherapy clinical trials for brain tumors.

    Dr. Lim’s bibliography contains well over 300 articles on topics such as immunotherapy for glioblastoma, long-term survival of glioma patients treated with stereotactic radiation, and treatment of neuropathic pain. His work has appeared in Science Translational Medicine, Clinical Cancer Research, Lancet Oncology, Nature Immunology, and many more publications. He also has written 20 book chapters and monographs.

    Dr. Lim is a world leader in immunotherapy for brain tumors. In addition to being invited world-wide to give lectures and seminars, he has given platform presentations on the topics of immunotherapy for brain tumors, neurosurgical techniques and management of brain tumors at the American Society of Clinical Oncologists, American Academy of Neurological Surgeons, Radiological Society of North America, Annual Symposium on Brain and Spine Metastases, Congress of Neurological Surgeons, and other meetings. In addition, he has served as platform chairman of the CNS session at the American Society for Clinical Oncology conference.

    Dr. Lim is a member of the American Society for Clinical Oncology, Congress of Neurological Surgeons, American Association of Neurological Surgeons, and Society for Neuro-Oncology. Dr. Lim served as the program co-chair of the Society for Neuro-Oncology and CNS section of the American Society for Clinical Oncology. He also served on many executive committees, including the Executive Committee for the Joint Tumor Section of the American Association of Neurological Surgeons and Congress of Neurological Surgeons.

  • Feng Vankee Lin

    Feng Vankee Lin

    Clinical Professor, Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsMy career has been devoted to understanding the neural mechanisms involved in brain aging and brain plasticity, with a special focus on early detection and prevention of Alzheimer’s disease (AD). My research approach integrates principles and findings from cognitive theory, clinical neuroscience, and computational neuroscience.

  • Michael Lin

    Michael Lin

    Associate Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.

  • Christian Linder

    Christian Linder

    Professor of Civil and Environmental Engineering and, by courtesy, of Mechanical Engineering

    BioChristian Linder is a Professor of Civil and Environmental Engineering and, by courtesy, of Mechanical Engineering. Through the development of novel and efficient in-house computational methods based on a sound mathematical foundation, the research goal of the Computational Mechanics of Materials (CM2) Lab at Stanford University, led by Dr. Linder, is to understand micromechanically originated multi-scale and multi-physics mechanisms in solid materials undergoing large deformations and fracture. Applications include sustainable energy storage materials, flexible electronics, and granular materials.

    Dr. Linder received his Ph.D. in Civil and Environmental Engineering from UC Berkeley, an MA in Mathematics from UC Berkeley, an M.Sc. in Computational Mechanics from the University of Stuttgart, and a Dipl.-Ing. degree in Civil Engineering from TU Graz. Before joining Stanford in 2013 he was a Junior-Professor of Micromechanics of Materials at the Applied Mechanics Institute of Stuttgart University where he also obtained his Habilitation in Mechanics. Notable honors include a Fulbright scholarship, the 2013 Richard-von-Mises Prize, the 2016 ICCM International Computational Method Young Investigator Award, the 2016 NSF CAREER Award, and the 2019 Presidential Early Career Award for Scientists and Engineers (PECASE).

  • Scott W Linderman

    Scott W Linderman

    Assistant Professor of Statistics and, by courtesy, of Computer Science and of Electrical Engineering

    BioScott is an Assistant Professor of Statistics and, by courtesy, Electrical Engineering and Computer Science at Stanford University. He is also an Institute Scholar in the Wu Tsai Neurosciences Institute and a member of Stanford Bio-X and the Stanford AI Lab. His lab works at the intersection of machine learning and computational neuroscience, developing statistical methods to analyze large scale neural data. Previously, Scott was a postdoctoral fellow with Liam Paninski and David Blei at Columbia University, and he completed his PhD in Computer Science at Harvard University with Ryan Adams and Leslie Valiant. He obtained his undergraduate degree in Electrical and Computer Engineering from Cornell University and spent three years as a software engineer at Microsoft before graduate school.

  • Wendy Liu, MD, PhD

    Wendy Liu, MD, PhD

    Assistant Professor of Ophthalmology

    Current Research and Scholarly InterestsDr. Liu's research interests include the role of mechanosensation in the eye as it relates to the pathophysiology of glaucoma, with the goal of finding new druggable targets in glaucoma treatment.

  • James Lock

    James Lock

    Eric Rothenberg, MD Professor and Professor, by courtesy, of Pediatrics

    Current Research and Scholarly InterestsJames Lock, MD, Ph.D. is Professor of Child Psychiatry and Pediatrics in the Department of Psychiatry and Behavioral Sciences at Stanford University School of Medicine where he has taught since 1993. He is board certified in adult as well as child and adolescent psychiatry. He directs the eating disorder program in Child Psychiatry and is active in treatment research for children and adolescents with eating disorders.

  • Kyle Loh

    Kyle Loh

    Assistant Professor of Developmental Biology (Stem Cell)

    BioHow the richly varied cell-types in the human body arise from one embryonic cell is a biological marvel and mystery. We have mapped how human embryonic stem cells develop into over twenty different human cell-types. This roadmap allowed us to generate enriched populations of human liver, bone, heart and blood vessel precursors in a Petri dish from embryonic stem cells. Each of these tissue precursors could regenerate their cognate tissue upon injection into respective mouse models, with relevance to regenerative medicine. In addition to our interests in developmental and stem cell biology, we also interested in discovering the entry receptors and target cells of deadly biosafety level 4 viruses, together with our collaborators.

    Kyle attended the County College of Morris and Rutgers University, and received his Ph.D. from Stanford University (working with Irving Weissman), with fellowships from the Hertz Foundation, National Science Foundation and Davidson Institute for Talent Development. He then continued as a Siebel Investigator, and later, as an Assistant Professor and The Anthony DiGenova Endowed Faculty Scholar at Stanford, where he is jointly appointed in the Department of Developmental Biology and Institute for Stem Cell Biology & Regenerative Medicine. Kyle is a Packard Fellow, Pew Scholar, Human Frontier Science Program Young Investigator and Baxter Foundation Faculty Scholar, and his research has been recognized by the NIH Director's Early Independence Award, Forbes 30 Under 30, Harold Weintraub Graduate Award, Hertz Foundation Thesis Prize and A*STAR Investigatorship.

  • Jonathan Z. Long

    Jonathan Z. Long

    Associate Professor of Pathology

    BioDr. Jonathan Long is an Associate Professor of Pathology and an Institute Scholar of Stanford ChEM-H (Chemistry, Engineering & Medicine for Human Health). His laboratory studies signaling pathways in mammalian energy metabolism. The long-term goal of this program is to discover new molecules and pathways that can be translated into therapeutic opportunities for obesity, metabolic disease, and other age-associated chronic diseases. Work from the laboratory has been recognized by numerous awards from the Alfred P. Sloan Foundation, the National Institutes of Health, the American Diabetes Association, and the Ono Pharma Foundation. Prior to arriving to Stanford, Dr. Long completed his Ph.D. in Chemistry at Scripps Research and his postdoctoral work at Harvard Medical School.

  • Frank M. Longo, MD, PhD

    Frank M. Longo, MD, PhD

    George E. and Lucy Becker Professor of Medicine and Professor, by courtesy, of Neurosurgery
    On Leave from 11/01/2023

    Current Research and Scholarly InterestsClinical interests include Alzheimer's disease and Huntington's disease and the development of effective therapeutics for these disorders. Laboratory interests encompass the elucidation of signaling mechanisms relevant to neurodegenerative disorders and the development of novel small molecule approaches for the treatment of neurodegenerative and other neurological disorders.

  • Billy W Loo, Jr, MD PhD FASTRO FACR

    Billy W Loo, Jr, MD PhD FASTRO FACR

    Professor of Radiation Oncology (Radiation Therapy)

    Current Research and Scholarly InterestsMy clinical specialty is radiation treatment of thoracic cancers.

    My research is on developing next-generation ultra-rapid radiation therapy technology (PHASER) and studying the radiobiological effects of FLASH treatment.

    My clinical research is on advanced 4-D image-guided radiation therapy and stereotactic ablative radiotherapy (SABR), and functional and metabolic imaging and imaging biomarkers.