Bio-X
Showing 901-1,000 of 1,131 Results
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Birgitt Schuele
Associate Professor (Research) of Pathology and, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsThe Schuele lab focuses on neurogenetics, human stem cell modeling, and gene therapy approaches to uncover disease mechanisms and pathways involved in neurodegeneration in Parkinson's, Alzheimer's disease and related disorders.
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Kevin Schulman
Professor of Medicine (Hospital Medicine), by courtesy, of Health Policy and of Operations, Information and Technology at the Graduate School of Business
BioDr. Schulman is a Professor of Medicine, and, by courtesy, Professor of Operations, Information and Technology at Stanford’s Graduate School of Business. He serves as Interim Division Co-Chief for the Division of Hospital Medicine at Stanford, and as an Associate Chair of the Department of Medicine. He is the Faculty Director of Stanford’s new applied master degree program, the Master of Science in Clinical Informatics Management program. He also serves as Deputy Director of the Clinical Excellence Research Center (CERC) at the Stanford University School of Medicine, and has an appointment in the Department of Health Policy (by courtesy).
Dr. Schulman is a health economist/health services researcher working at the intersection of business, medicine and technology. With over 500 publications, he has had a broad impact on several areas of health policy (Scopus h-index=81). His research has appeared in the New England Journal of Medicine, the Journal of the American Medical Association, and Health Affairs. He is the editor-in-chief of Health Management, Policy and Innovation (www.HMPI.Org), and Senior Associate Editor of Health Service Research (HSR).
He is a graduate of Dartmouth College, the New York University School of Medicine, and The Wharton Health Care Management Program. He is an elected member of ASCI and AAP. -
Molly Schumer
Associate Professor of Biology
BioMolly Schumer is an Assistant Professor in Biology. She is interested in genetics and evolutionary biology. After receiving her PhD at Princeton, she did her postdoctoral work at Columbia and was a Junior Fellow in the Harvard Society of Fellows and Hanna H. Gray Fellow at Harvard Medical School. Current research in the lab centers on understanding the genetic mechanisms of evolution, with a focus on natural populations.
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Daniel Schwartz
Dean of the Graduate School of Education and the Nomellini & Olivier Professor of Educational Technology
Current Research and Scholarly InterestsInstructional methods, transfer of learning and assessment, mathematical development, teachable agents, cognition, and cognitive neuroscience.
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Matthew P. Scott
Professor of Developmental Biology, Emeritus
Current Research and Scholarly InterestsOur research has been focused on the genetic regulation of animal development and its relation to birth defects, cancer, and neurodegeneration. We studied mechanisms and functions of Hedgehog (Hh) signaling, which controls cell fates and growth, in the context of normal development and brain cancer. We studied a neurodegenerative disease, Niemann-Pick C syndrome, that affects intracellular organelle movements and sterol homeostasis. Due to Dr. Scott's new job, the lab is no longer active.
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Vittorio Sebastiano
Associate Professor (Research) of Obstetrics and Gynecology (Reproductive, Perinatal & Stem Cell Biology Research)
Current Research and Scholarly InterestsThe thread of Ariadne that connects germ cells, preimplatation development and pluripotent stem cells is the focus of my research, with a specific interest in human development. My long-term goals are: 1. Understanding the biology of germ cells and and their ability to sustain early preimplantation development; 2. Understanding the mechanisms that regulate very early cell fate decisions in human embryos; 3. Understanding the biology of derivation and maintenance of Pluripotent Stem Cells
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Debbie Senesky
Associate Professor of Aeronautics and Astronautics, of Electrical Engineering and Senior Fellow at the Precourt Institute for Energy
BioDebbie G. Senesky is an Associate Professor at Stanford University in the Aeronautics and Astronautics Department and the Electrical Engineering Department. In addition, she is the Principal Investigator of the EXtreme Environment Microsystems Laboratory (XLab). Her research interests include the development of nanomaterials for extreme harsh environments, high-temperature electronics for Venus exploration, and microgravity synthesis of nanomaterials. In the past, she has held positions at GE Sensing (formerly known as NovaSensor), GE Global Research Center, and Hewlett Packard. She received the B.S. degree (2001) in mechanical engineering from the University of Southern California. She received the M.S. degree (2004) and Ph.D. degree (2007) in mechanical engineering from the University of California, Berkeley. Prof. Senesky is the Site Director of nano@stanford. She is currently the co-editor of two technical journals: IEEE Journal of Microelectromechanical Systems and Sensors. In recognition of her research, she received the Presidential Early Career Award for Scientists and Engineers (PECASE) in 2025, Emerging Leader Abie Award from AnitaB.org in 2018, Early Faculty Career Award from the National Aeronautics and Space Administration (NASA) in 2012, Gabilan Faculty Fellowship Award in 2012, and Sloan Ph.D. Fellowship from the Alfred P. Sloan Foundation in 2004.
Prof. Senesky's career path and research has been featured by Scientific American, Seeker, People Behind the Science podcast, The Future of Everything radio show, Space.com, and NPR's Tell Me More program. More information about Prof. Senesky can be found at https://xlab.stanford.edu and on Instagram (@astrodebs). -
Kawin Setsompop
Professor of Radiology (Radiological Sciences Laboratory) and, by courtesy, of Electrical Engineering
BioKawin Setsompop is a Professor of Radiology and, by courtesy, of Electrical Engineering. His research focuses on the development of novel MRI acquisition methods, with the goal of creating imaging technologies that can be used to help better understand brain structure and function for applications in Healthcare and Health sciences. He received his Master’s degree in Engineering Science from Oxford University and his PhD in Electrical Engineering and Computer Science from MIT. Prior to joining Stanford, he was a postdoctoral fellow and subsequently a faculty at the A.A. Martinos center for biomedical imaging, MGH, as well as part of the Harvard and MIT faculty. His group has pioneered several widely-used MRI acquisition technologies, a number of which have been successfully translated into FDA-approved clinical products on Siemens, GE, Phillips, United Imaging and Bruker MRI scanners worldwide. These technologies are being used daily to study the brain in both clinical and neuroscientific fields.
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Robert W. Shafer
Professor (Research) of Medicine (Infectious Diseases) and, by courtesy, of Pathology
Current Research and Scholarly InterestsMy group’s research is on the mechanisms and consequences of virus evolution with a focus on HIV therapy and drug resistance. We maintain a public HIV drug resistance database (http://hivdb.stanford.edu) as a resource for HIV drug resistance surveillance, interpreting HIV drug resistance tests, and HIV drug development. Our paramount goal is to inform HIV treatment and prevention policies by identifying the main factors responsible for the emergence and spread of drug resistance.
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Nigam H. Shah, MBBS, PhD
Professor of Medicine (Biomedical Informatics) and of Biomedical Data Science
Current Research and Scholarly InterestsWe answer clinical questions using aggregate patient data at the bedside. The Informatics Consult Service (https://greenbutton.stanford.edu/) put this idea in action and led to the creation of Atropos Health. We build predictive models that allow taking mitigating actions, keeping the human in the loop.
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Nirao Shah
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator), of Neurobiology and, by courtesy, of Obstetrics and Gynecology
Current Research and Scholarly InterestsWe study how our brains generate social interactions that differ between the sexes. Such gender differences in behavior are regulated by sex hormones, experience, and social cues. Accordingly, we are characterizing how these internal and external factors control gene expression and neuronal physiology in the two sexes to generate behavior. We are also interested in understanding how such sex differences in the healthy brain translate to sex differences in many neuro-psychiatric illnesses.
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Mohammad Shahrokh Esfahani
Assistant Professor of Radiation Oncology (Radiation and Cancer Biology)
BioWith a primary focus on high-dimensional data, I have significant expertise in developing machine learning tools. Much of my work involves constructing Bayesian models, which effectively convert 'prior knowledge', either inherent in the dataset or obtained from external sources, into mathematical terms—more specifically, prior probabilities.
My recent research efforts have centered on the analysis of genetic and epigenetic signals within cell-free DNA assays. This interest in epigenetics led to the development of a pioneering technique known as EPIC-seq, which has broadened our understanding of this complex field.
It's notable that traditional computational methods in cancer genomics often fall short when confronted with an exceedingly low signal-to-noise ratio—a common scenario in cfDNA analyses. As such, there's an emerging need to devise innovative, robust methods capable of overcoming this limitation—a research area that I'm deeply committed to and actively engaged in. -
Cory Shain
Assistant Professor of Linguistics and, by courtesy, of Psychology
BioI lead the Laboratory for Computation & Language in Minds & Brains (CLiMB Lab). We try to figure out how our brains let us go so efficiently from sensation (e.g., speech, reading) to meaning, and we do this using a combination of neuroimaging, computer modeling, and behavioral experiments. See the lab website for details.
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Mehrdad Shamloo
Professor (Research) of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsThe ultimate goal of the Shamloo laboratory is to rapidly advance our understanding of brain function at the molecular, cellular, circuit and behavioral levels, and to elucidate the pathological process underlying malfunction of the nervous system following injury and neurologic disorders such as stroke, Alzheimer's disease, Parkinson’s disease, and autism. We have been focusing on the noradrenergic system and approaches leading to restoration of brain adrenergic signaling in these disorders.
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Lucy Shapiro
Virginia and D. K. Ludwig Professor, Emerita
Current Research and Scholarly InterestsA basic question in developmental biology involves the mechanisms used to generate the three-dimensional organization of a cell from a one-dimensional genetic code. Our goal is to define these mechanisms using both molecular genetics and biochemistry.
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Eric S.G. Shaqfeh
Lester Levi Carter Professor and Professor of Mechanical Engineering
Current Research and Scholarly InterestsI have over 25 years experience in theoretical and computational research related to complex fluids following my PhD in 1986. This includes work in suspension mechanics of rigid partlcles (rods), solution mechanics of polymers and most recently suspensions of vesicles, capsules and mixtures of these with rigid particles. My research group is internationally known for pioneering work in all these areas.
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Naima G. Sharaf
Assistant Professor of Biology and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsResearch in the lab bridges biology, microbiology, and immunology to translate lipoprotein research into therapeutics
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Carla Shatz
Sapp Family Provostial Professor and Professor of Biology and of Neurobiology
Current Research and Scholarly InterestsThe goal of research in the Shatz Laboratory is to discover how brain circuits are tuned up by experience during critical periods of development both before and after birth by elucidating cellular and molecular mechanisms that transform early fetal and neonatal brain circuits into mature connections. To discover mechanistic underpinnings of circuit tuning, the lab has conducted functional screens for genes regulated by neural activity and studied their function for vision, learning and memory.
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Gary M. Shaw
Rosemarie Hess Professor and Professor (Research), by courtesy, of Epidemiology and Population Health and of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly InterestsPrimary research interests include 1) epidemiology of birth defects, 2) gene-environment approaches to perinatal outcomes, and 3) nutrition and reproductive outcomes.
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Kevin Shea
Chambers-Okamura Endowed Professor of Pediatric Orthopaedics
BioKevin G. Shea, MD is at Stanford University. He grew up in Montana and California, graduated from the University of Notre Dame, UCLA School of Medicine, and completed his orthopaedic residency at the University of Utah. His advanced training includes pediatric orthopaedics at Rady Children’s Hospital in San Diego, AO Fellowship in Bern Switzerland with Dr. Ganz (Hip), Dr. Diego Fernandez (Trauma), and Dr. Hans Staubli (sports), Ilizarov Training in Lecco, Italy. He has done the AOSSM South American Traveling Sports Medicine Fellowship, and education in Russia and former Soviet Bloc countries. Most of his early career was in Boise, Idaho. Dr. Shea is a founding member of the PRISM Society (Pediatric Research in Sports Medicine) and the ROCK (Research in Osteochondritis Dissecans of the Knee) Multi-center Study Group, and the SCORE (Sports Cohort Outcomes Research ) Multi-Center Registry for pediatric sports. He has authored more than 300 scientific papers and chapters. His clinic research interests include cartilage and ligament disorders, using pediatric cadaveric tissue and surgical 3D simulations to develop surgeries and improve outcomes for procedures that avoid damage to growth plates. He has years of experience with performance, quality improvement, value, and he worked extensively with the AAOS Quality/Clinical Practice Guideline Committees. He is one of the POSNA members to launch the POSNA Safe Surgery Program. He is a national quality leader in health care with interests in patient safety, risk reduction, and improving value in health care with clinician integration into supply chain. He is an avid cyclist, trail runner, hiker, and spends as much time outside as possible, with his partner Lonnie and their children Beck and Cooper.
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Jeanne Shen
Associate Professor of Pathology
Current Research and Scholarly InterestsGastrointestinal and pancreatobiliary pathology, with major emphasis on GI and pancreatic neoplasia, inflammatory bowel disease, biodesign innovation, and the application of machine learning to digital pathology.
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Kang Shen
Vincent V.C. Woo Director, Wu Tsai Neurosciences Institute, Frank Lee and Carol Hall Professor and Professor of Biology and of Pathology
Current Research and Scholarly InterestsThe connectivity of a neuron (its unique constellation of synaptic inputs and outputs) is essential for its function. Neuronal connections are made with exquisite accuracy between specific types of neurons. How each neuron finds its synaptic partners has been a central question in developmental neurobiology. We utilize the relatively simple nervous system of nematode C. elegans, to search for molecules that can specify synaptic connections and understand the molecular mechanisms of synaptic as
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Krishna Shenoy
Member, Bio-X
Current Research and Scholarly InterestsWe conduct neuroscience, neuroengineering and translational research to better understand how the brain controls movement, and to design medical systems to assist people with paralysis. These are referred to as brain-machine interfaces (BMIs), brain-computer interfaces (BCIs) and intra-cortical neural prostheses. We conduct this research as part of our Neural Prosthetic Systems Lab (NPSL) and our Neural Prosthetics Translational Lab (NPTL), which I co-direct with Prof. Jaimie Henderson, M.D.
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Sheri D. Sheppard
Richard W. Weiland Professor in the School of Engineering, Emerita
BioSheri Sheppard teaches both undergraduate and graduate design-related classes, and conducts research on fracture mechanics and applied finite element analysis, and on how people become engineers. From 1999-2008 she served as a Senior Scholar at the Carnegie Foundation for the Advancement of Teaching, leading the Foundation’s engineering study. In addition to publishing technical papers, reports, and textbooks, she has led or co-led several large, multi-institutional projects to build new educational research programs and related resources, such as the Center for the Advancement of Engineering Education (CAEE), The National Center for Engineering Pathways to Innovation (Epicenter), and a program on summer research experiences for high school teachers. Her industry experience includes engineering positions at Detroit's "Big Three” — Ford Motor Company, General Motors Corporation, and Chrysler Corporation. She earned her bachelors degree from the University of Wisconsin, and her PhD at the University of Michigan. At Stanford she has served a chair of the faculty senate, as associate vice provost for graduate education, and is the longtime faculty founder of and adviser to the graduate student group MEwomen. Her work has been recognized with numerous honors and awards, including the Walter J. Gores Award, Stanford University's highest award for excellence in teaching and the Chester F. Carlson and Ralph Coats Roe Awards of the American Society for Engineering Education in recognition of distinguished accomplishment in engineering education, and for outstanding teaching and notable contributions to the mechanical engineering profession.
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Gavin Sherlock
Professor of Genetics
Current Research and Scholarly InterestsEvolution and the adaptive landscape using yeast as a model; Defining yeast transcriptomes; chromosomal evolution in hybrid yeast species
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Aditi Sheshadri
Assistant Professor of Earth System Science and Center Fellow, by courtesy, at the Woods Institute for the Environment
BioI joined Stanford's Earth System Science department as an assistant professor 2018. Prior to this, I was a a Junior Fellow of the Simons Foundation in New York, and a postdoctoral research scientist at Columbia University’s Department of Applied Physics and Applied Math and the Lamont-Doherty Earth Observatory. I got my Ph.D. in Atmospheric Science at MIT's Department of Earth, Atmospheric, and Planetary Sciences, in the Program for Atmospheres, Oceans, and Climate, where I worked with R. Alan Plumb. I’m broadly interested in atmosphere and ocean dynamics, climate variability, and general circulation.
I'm particularly interested in fundamental questions in atmospheric dynamics, which I address using a combination of theory, observations, and both idealized and comprehensive numerical experiments. Current areas of focus include the dynamics, variability, and change of the mid-latitude jets and storm tracks, the stratospheric polar vortex, and atmospheric gravity waves. -
Vipul Sheth, MD, PhD
Assistant Professor of Radiology (Body MRI)
Current Research and Scholarly InterestsMy interests are in the development and translation of imaging technologies geared toward disease detection and characterization to better guide prognosis, treatment, and improve outcomes. I’m interested in supporting the development of MRI guided focal therapy methods which can personalize treatment and reduce the risk of morbidity from more invasive therapies.
Clinical Interests
- MRI for diagnosis of pelvic floor disorders
- MRI and PET/MRI to pelvic malignancies and lymph node staging.
- Whole Body MRI
- MRI guided procedures including biopsies, cryoablation, and high intensity focused ultrasound.
Translational Research Interests
- Development and translation of magnetic resonance imaging technologies to improve both diagnostics and therapeutics
- Molecular imaging and characterization of the tumor microenvironment
- Ultrashort echo time MRI applications in the body
- Developing synergistic MRI methods to complement PET in potential applications for PET/MRI -
Judith Shizuru
Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
Current Research and Scholarly InterestsTransplantation of defined populations of allogeneic hematopoietic cells. Specifically, the way in which hematopoietic cell grafts alter antigen specific immune responses to allo-, auto- and viral antigens. The cellular and molecular basis of resistance to engraftment of allogeneic hematopoietic stem cells.
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Linda M. Dairiki Shortliffe
Stanley McCormick Memorial Professor in the School of Medicine, Emerita
Current Research and Scholarly InterestsThe timing for intervention in obstruction in the infant and child is poorly understood.Our group has been interested in trying to define the risks that may be involved in obstructive and infectious uropathies and discovering early signs of damage to the urinary tract and kidney. We have explored ways of imaging the urinary tract using nonionizing radiation (US, MRI). We have studied the relationships of sex steroid hormones, pregnancy, reflux, urinary tract infection and urinary tract function.
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Joseph Shrager
Professor of Cardiothoracic Surgery
Current Research and Scholarly InterestsIn clinical research, Dr. Shrager studies outcomes in a variety of areas within Thoracic Surgery including: parenchyma-sparing operations and minimally invasive resections for lung cancer, transcervical thymectomy for myasthenia gravis, diaphragm plication, and surgical treatment of emphysema.
Dr. Shrager's lab is focused on the impact of disease states upon the diaphragm. His group published the seminal paper (NEJM) describing diaphragm atrophy assoc'd with mechanical ventilation. -
Surbhi Sidana, MD
Associate Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
BioDr. Surbhi Sidana is an Associate Professor of Medicine at Stanford University and specializes in the treatment of multiple myeloma and related disorders. She leads the Myeloma CAR-T/Immunotherapy program at Stanford.
Dr Sidana grew up in Delhi, India. She completed her Internal Medicine Residency at Cleveland Clinic in Cleveland, Ohio, followed by Hematology/Oncology fellowship at Mayo Clinic in Rochester, MN. Following this, she completed an Advanced Hematology Fellowship in Myeloma, Amyloidosis and Related Disorders at Mayo Clinic in Rochester, MN before joining Stanford University as a faculty member in 2019, where she has led the development of the myeloma CAR-T and bispecific antibody program.
Dr Sidana has an active, broad research portfolio that includes clinical trials of novel therapies in myeloma and related disorders, translational research, epidemiologic and patient reported outcome studies. She has a special focus on research with immunotherapies such as CAR-T cell therapy and bispecific antibodies. She has published over 100 research manuscripts. Dr Sidana is the Leader of the Myeloma Disease Focused Group and the Associate Director for Clinical Research in the BMT and Cell Therapy Division at Stanford University. She also co-leads a multi-institutional collaboration on real world outcomes with immunotherapies in myeloma.
Dr Sidana is actively involved in and holds leadership positions in national and international professional societies. She is the Chair of the American Society of Hematology Committee on Communications, and Co-Chairs the Quality-of-Life Committee of the International Myeloma Working Group. She is a member of the SWOG Myeloma Committee and BMT CTN Myeloma Intergroup, where she works with colleagues across the nation to develop innovative and practice changing trials focused on multiple myeloma . -
Arend Sidow
Professor of Pathology and of Genetics
Current Research and Scholarly InterestsWe have a highly collaborative research program in the evolutionary genomics of cancer. We apply well-established principles of phylogenetics to cancer evolution on the basis of whole genome sequencing and functional genomics data of multiple tumor samples from the same patient. Introductions to our work and the concepts we apply are best found in the Newburger et al paper in Genome Research and the Sidow and Spies review in TIGS.
More information can be found here: http://www.sidowlab.org -
Julia Fridman Simard
Associate Professor of Epidemiology and Population Health, of Medicine (Immunology & Rheumatology) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
BioJulia Fridman Simard, ScD, is an Associate Professor of Epidemiology & Population Health, and of Medicine in Immunology and Rheumatology and Obstetrics and, by courtesy, Gynecology in Maternal Fetal Medicine at Stanford University School of Medicine.
Dr. Simard earned her Masters and Doctorate of Science in Epidemiology degrees at the Harvard School of Public Health. During that time she trained with investigators at the Section of Clinical Sciences, Division of Rheumatology, Immunology, and Allergy at Brigham and Women’s Hospital and the Cardiovascular Epidemiology Research Unit at Beth Israel Deaconess Medical Center. In 2008, Dr. Simard relocated to Sweden to begin a Postdoctoral Fellowship in Clinical Epidemiology at the Karolinska Institutet in Stockholm. She became an Assistant Professor in their Clinical Epidemiology Unit in 2011, and was later honored with a Karolinska Institutet Teaching Award. Leveraging the population-based registers of Sweden, Dr. Simard initiated a national register linkage study to examine the utility of registers in Systemic Lupus Erythematosus (SLE) research and develop an extensive data repository for future epidemiologic investigations.
While maintaining a close collaboration with the Karolinska Institutet, she joined Stanford’s Epidemiology faculty in 2013. Dr. Simard studies outcomes such as malignancy, stroke, infection, and mortality, in patients with systemic autoimmune rheumatic diseases with a focus on systemic lupus erythematosus. Recently her primary research focus has shifted to the intersection between reproductive epidemiology and rheumatic disease fueled by a K01 career development award from the NIH (NIAMS) to study maternal and fetal outcomes in systemic lupus pregnancy. This led to collaborations with colleagues at Stanford, throughout the US, and abroad, and a series of projects focused on the diagnosis of preeclampsia and associated risks in pregnant women with systemic lupus. Dr. Simard was awarded a Peter Joseph Pappas Research Grant from the Preeclampsia Foundation for her lab's work examining preeclampsia risk in high-risk populations, and a McCormick Faculty Award from Stanford Medicine to take important steps towards disentangling preeclampsia from lupus nephritis. Dr. Simard is leading an international study of hydroxychloroquine in lupus pregnancy leveraging mixed methods in partnership with qualitative researchers, patients, clinicians, and epidemiologists in Sweden, Canada, and in the United States.
In addition to these issues of misclassification in reproductive rheumatology questions, Dr. Simard's lab is also interested in how misclassification, missed opportunities, and misdiagnosis contribute to disparities in complex conditions such as systemic lupus. In addition to methodologic issues around misclassification and bias and the largely clinical epidemiology focus of her work, Dr. Simard's work examines social determinants of health and health disparities. Dr. Simard was recently awarded an R01 from NIH (NIAID) to study the role of cognitive errors in clinical decision making for female-predominant diseases including lupus and multiple sclerosis. This work evaluates this bias in multiple clinical specialties, including rheumatology, neurology, and primary care, and uses mixed methods. -
Laura Simons
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric)
Current Research and Scholarly InterestsI am a Professor in the Department of Anesthesiology, Perioperative, and Pain Medicine at Stanford University School of Medicine and a clinical psychologist who evaluates and treats youth presenting with chronic pain in the Pediatric Pain Management Clinic (PPMC) at Stanford Children’s Health. My program of research aims to utilize a pain neuroscience psychology approach to gain a mechanistic understanding of cognitive and affective processes in pediatric pain, perform rigorous patient-oriented research that translates targeted assessment into mechanistically informed treatment approaches for optimal clinical care and leverage the ubiquity of digital health to enhance patient access and reach. Central to these goals are projects targeting adolescence and youth adults with chronic pain that encompass defining brain signatures of threat interpretation, evaluating the efficacy of graded exposure (NCT03699007), deriving a biosignature of improvement vs. persistence of pain and disability (NCT04285112), and evaluating the impact of virtual reality on pain rehabilitation (NCT04636177). These studies along with additional work examining the journey of pain care for youth with pain and their parents form a comprehensive research portfolio in the realm of understanding and treating chronic pain in young people. My long-term career goal is to lead a robust research program focusing on alleviating the suffering of youth and emerging adults with chronic pain.
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Robert Sinclair
Charles M. Pigott Professor in the School of Engineering
BioUsing high-resolution transmission electron microscopy, Sinclair studies microelectronic, magnetic thin film microstructure and nanomaterials.
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Kuldev Singh, MD, MPH
Professor of Ophthalmology
Current Research and Scholarly InterestsGlaucoma, clinical epidemiology
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Upinder Singh
Stanford Medicine Professor of Infectious Disease and Professor of Medicine (Infectious Diseases & Geographic Medicine), Emerita
Current Research and Scholarly InterestsOur lab elucidates the molecular basis of pathogenesis of the protozoan parasite Entamoeba histolytica. We use genetic and genomic approaches to identify novel virulence determinants and to characterize the global epidemiology of the parasite.
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Sidhartha Sinha
Assistant Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsThere are two primary and overlapping emphases of my research, both of which are driven and united by needs-based innovation and translational potential:
(1) Understanding the microenvironment of the inflamed versus normal gut in order to identify better therapeutic targets for people with immune-¬mediated GI disorders. Here, our investigations include understanding the influence and interactions of pharmacologic and dietary interventions on gut microbiome/metabolomic changes and the host immune response. In the context of providing patients with new understanding and solutions for their disease, I have led and advised on the design of both pilot and large clinical trials (including new FDA approved therapies) for anti-inflammatory therapies;
(2) Applying novel approaches and technologies (including natural language processing, computer vision, and reinforcement learning) to identify and address unmet clinical needs. In this area we have ongoing and published efforts in my lab to validate and develop solutions to pressing clinical needs. We have developed/led new drug delivery technologies with a multidisciplinary team that have shown strong potential in ongoing human IBD clinical trials. My lab has utilized both supervised and unsupervised approaches to analyze social media discourse and unstructured data sets for identifying patient needs that are rarely addressed in clinical settings. We have gained insights into patient perceptions around preventative health interventions, such as health screening and diet, including the dearth of evidence-based dietary recommendations to treat IBD (despite strong patient desire for solutions in this domain). -
Tammy Lisa Sirich
Assistant Professor of Medicine (Nephrology)
Current Research and Scholarly InterestsI conduct translational research focused on uremia and dialysis. I use mass spectrometry to conduct studies testing ways to reduce levels of solutes and examining the contribution of uremic solutes to illness.
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Stephen Skirboll
Associate Professor of Neurosurgery
Current Research and Scholarly InterestsMy research focuses on screening strategies to identify and characterize cancer stem cells (CSCs) in human gliomas. We are pursuing this in several ways: 1) a novel colony-forming antibody live cell array to identify distinct CSC surface phenotypes, 2) RNAi screens to identify kinases critical for CSC tumorigenicity, 3) high throughput small molecule and chemical screens to identify compounds that selectively kill or target CSCs, and 4) identifying CSCs using the tumor specific EGFRvIII
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Jan Skotheim
Professor of Biology and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsMy overarching goal is to understand how cell growth triggers cell division. Linking growth to division is important because it allows cells to maintain specific size range to best perform their physiological functions. For example, red blood cells must be small enough to flow through small capillaries, whereas macrophages must be large enough to engulf pathogens. In addition to being important for normal cell and tissue physiology, the link between growth and division is misregulated in cancer.
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Melody Smith, MD, MS
Assistant Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy)
BioDr. Smith is a board-certified, fellowship-trained medical oncologist and hematologist. She is an Assistant Professor in the Department of Medicine within the Division of Blood & Marrow Transplantation and Cellular Therapy.
She is also a physician-scientist who conducts extensive research. As a medical student, she completed a fellowship at the National Institutes of Health (NIH) in the Clinical Research Training (now, the Medical Research Scholars) Program. Subsequently, after her clinical fellowship, she was a post-doctoral researcher at Memorial Sloan Kettering Cancer Center. Her lab's research focuses on studying the biology of chimeric antigen receptor (CAR) T cells to improve the therapy's efficacy and safety (1) by examining donor (Nature Medicine, 2017) and off-the-shelf CAR T cells in mouse models and (2) by investigating how the intestinal microbiome affects CAR T cell response (Nature Medicine, 2022).
Dr. Smith presents her research findings at regional, national, and international conferences. Additionally, she has co-authored articles on topics in cancer immunology, including cancer immunotherapy, stem cell transplantation, and CAR T cell therapy. Her work has been published in journals such as Nature, Nature Immunology, Nature Medicine, Blood, and Transplantation and Cellular Therapy. She serves as a peer reviewer for publications like NEJM Evidence, Science Advances, Blood, Cancer Cell, and Molecular Therapy. She has also contributed chapters to books, including Pocket Oncology, Current Concepts and Controversies in Hematopoietic Cell Transplantation, and Advanced Concepts in Human Immunology: Prospects for Disease Control.
She has received numerous honors; the American Society of Hematology, the American Society for Clinical Investigation, the Society for Immunotherapy of Cancer, the European Society for Blood and Marrow Transplantation, and several other professional organizations have recognized her achievements as a clinician, researcher, and scholar. -
Robert Lane Smith
Professor (Research) of Orthopedic Surgery, Emeritus
Current Research and Scholarly InterestsOur group is interested in the molecular and cell biology underlying bone and cartilage metabolism in health and disease. Normal daily activities are linked to the ability of the articular cartilage to withstand normal joint forces that may reach 5-7 times body weight and bone homeostasis depends on daily mechanical loading histories.
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Stephen J Smith
Professor of Molecular and Cellular Physiology, Emeritus
Current Research and Scholarly InterestsStephen Smith remains active in the computational microscopy field and is also currently using data science tools to explore new transcriptomic perspectives on signaling by neuropeptides and other neuromodulators in brains of diverse animal species. These exploration have unearthed evidence for a previous unrecognized ubiquity of local neuropeptide signaling and possible critical involvement of such signaling in memory engram formation.
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Matthew Smuck, MD
Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsI direct the Wearable Health Lab at Stanford, investigating medical applications of mobile technology to improve musculoskeletal and neurologic disease detection, treatment and prevention.
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Michael Snyder, Ph.D.
Stanford W. Ascherman Professor of Genetics
Current Research and Scholarly InterestsOur laboratory use different omics approaches to study a) regulatory networks, b) intra- and inter-species variation which differs primarily at the level of regulatory information c) human health and disease. For the later we have established integrated Personal Omics Profiling (iPOP), an analysis that combines longitudinal analyses of genomic, transcriptomic, proteomic, metabolomic, DNA methylation, microbiome and autoantibody profiles to monitor healthy and disease states
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Samuel So, MD
Lui Hac Minh Professor in the School of Medicine
Current Research and Scholarly InterestsThrough a 4 pronged comprehensive program: translational and clinical research, early detection and treatment, promoting education, awareness and immunization and building partnership, we are working towards the development of new strategies that will lead to the elimination of hepatitis B worldwide and reduce the threat and incidence of liver cancer. Current research efforts focus on evaluating potential new diagnostic and treatment markers and novel targeted therapy for primary liver cancer.
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Yuen So, MD, PhD
Professor of Neurology and Neurological Sciences (Adult Neurology), Emeritus
Current Research and Scholarly InterestsResearch in the diagnosis, pathophysiology and treatment of peripheral neuropathy, myasthenia gravis, motor neuron diseases including ALS and SMA, nerve injuries and muscle diseases. Application of clinical neurophysiological methods to neurological diagnosis. Development of evidence-based medicine pertaining to the practice of neurology.
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Bruno Passebon Soares, MD
Associate Professor of Radiology (Pediatric)
BioDr. Soares is an Associate Professor of Radiology at Stanford University School of Medicine and serves as the Section Chief of Pediatric Neuroradiology at Lucile Packard Children’s Hospital at Stanford since June 2023.
Born in Brazil, Dr. Bruno P. Soares obtained his medical degree from the Federal University of Rio de Janeiro and completed his residency in Diagnostic Radiology at the Federal University of Sao Paulo. After one year as a Research Fellow at the University of California San Francisco (UCSF), Dr. Soares completed clinical fellowships in Diagnostic Neuroradiology, Pediatric Radiology, and Pediatric Neuroradiology at UCSF, in addition to a clinical fellowship in PET/CT at the Dana-Farber Cancer Institute of Harvard Medical School in Boston. Dr. Soares holds a subspecialty certificate in Neuroradiology from the American Board of Radiology (ABR).
From July 2013 to July 2016, Dr. Soares was an Assistant Professor in the Division of Neuroradiology at Emory University in Atlanta. From August 2016 to November 2018, he worked at the Johns Hopkins University in Baltimore as an Assistant Professor in the Division of Pediatric Radiology and Neuroradiology. From December 2018 to May 2023, Dr. Soares worked at the University of Vermont Medical Center as Associate Professor of Radiology, Division Chief of Neuroradiology, Vice-Chair of Imaging Research, and Co-Director of the MRI Center for Biomedical Imaging.
Dr. Soares has published more than 85 peer-reviewed articles and has been the recipient of the Research Fellow Grant from the Society for Pediatric Radiology and of the Rad_Britestar Award from the Johns Hopkins Department of Radiology. The recognition for his teaching includes the 2013 Outstanding Clinical Fellow / Instructor Teaching Award from the UCSF Department of Radiology, the 2017 Teacher of Year Award from the Johns Hopkins Division of Pediatric Radiology, and the 2017 ASNR International Outreach Professor Program in Ghana.
Dr. Soares currently serves as an Editorial Board Member of Neuroradiology and of the Journal of Neuroimaging, and has served as an Editorial Board Member of the American Journal of Roentgenology (AJR) and of the American Journal of Neuroradiology (AJNR). Dr. Soares served for six years as a member of the ABR Neuroradiology Core Exam Committee, receiving ABR Volunteer Service Awards in 2022 and 2024.
His research has focused on neonatal and pediatric brain imaging. He is currently focused on developing semi-automated algorithms to quantify normal and abnormal brain development, and applying deep learning algorithms for detection of subtle cerebral abnormalities in children with epilepsy. -
Hyongsok Tom Soh
W. M. Keck Foundation Professor of Electrical Engineering, Professor of Radiology (Diagnostic Sciences Laboratory) and of Bioengineering
BioDr. Soh received his B.S. with a double major in Mechanical Engineering and Materials Science with Distinction from Cornell University and his Ph.D. in Electrical Engineering from Stanford University. From 1999 to 2003, Dr. Soh served as the technical manager of MEMS Device Research Group at Bell Laboratories and Agere Systems. He was a faculty member at UCSB before joining Stanford in 2015. His current research interests are in analytical biotechnology, especially in high-throughput screening, directed evolution, and integrated biosensors.
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Olav Solgaard
Audrey S. Hancock Professor in the School of Engineering
BioThe Solgaard group focus on design and fabrication of nano-photonics and micro-optical systems. We combine photonic crystals, optical meta-materials, silicon photonics, and MEMS, to create efficient and reliable systems for communication, sensing, imaging, and optical manipulation.
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Edward I. Solomon
Monroe E. Spaght Professor of Chemistry, Emeritus
Current Research and Scholarly InterestsProf. Solomon's work spans physical-inorganic, bioinorganic, and theoretical-inorganic chemistry, focusing on spectroscopic elucidation of the electronic structure of transition metal complexes and its contribution to reactivity. He has advanced our understanding of metal sites involved in electron transfer, copper sites involved in O2 binding, activation and reduction to water, structure/function correlations over non-heme iron enzymes, and correlation of biological to heterogeneous catalysis.
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Ivan Soltesz
James R. Doty Professor of Neurosurgery and Neurosciences
BioIvan Soltesz received his doctorate in Budapest and conducted postdoctoral research at universities at Oxford, London, Stanford and Dallas. He established his laboratory at the University of California, Irvine, in 1995. He became full Professor in 2003, and served as department Chair from 2006 to July 2015. He returned to Stanford in 2015 as the James R. Doty Professor of Neurosurgery and Neurosciences at Stanford University School of Medicine. His major research interest is focused on neuronal microcircuits, network oscillations, cannabinoid signaling and the mechanistic bases of circuit dysfunction in epilepsy.
His laboratory employs a combination of closely integrated experimental and theoretical techniques, including closed-loop in vivo optogenetics, paired patch clamp recordings, in vivo electrophysiological recordings from identified interneurons in awake mice, 2-photon imaging, machine learning-aided 3D video analysis of behavior, video-EEG recordings, behavioral approaches, and large-scale computational modeling methods using supercomputers. He is the author of a book on GABAergic microcircuits (Diversity in the Neuronal Machine, Oxford University Press), and editor of a book on Computational Neuroscience in Epilepsy (Academic Press/Elsevier). He co-founded the first Gordon Research Conference on the Mechanisms of neuronal synchronization and epilepsy, and taught for five years in the Ion Channels Course at Cold Springs Harbor. He has over 30 years of research experience, with over 20 years as a faculty involved in the training of graduate students (total of 16, 6 of them MD/PhDs) and postdoctoral fellows (20), many of whom received fellowship awards, K99 grants, joined prestigious residency programs and became independent faculty. -
George Somero
David and Lucile Packard Professor in Marine Science, Emeritus
Current Research and Scholarly InterestsWe examine two aspects of organism-environment interactions: How does stress from physical (e.g., temperature) and chemical (oxygen levels, pH) factors perturb organisms and how do organisms respond, adaptively, to cope with this stress? We examine evolutionary adaptation and phenotypic acclimatization using a wide variety of marine animals, including Antarctic fishes and invertebrates from intertidal habitats on the coastlines of temperate and tropical seas.
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Geoffrey Sonn
Associate Professor of Urology and, by courtesy, of Radiology (Body MRI)
Current Research and Scholarly InterestsMy interest is in improving prostate cancer diagnosis through MRI and image-targeted prostate biopsy. In collaboration with radiologists at Stanford, we are working to define the optimal role of MRI in prostate cancer. We hope to improve cancer imaging to the point that some men with elevated PSA may safely avoid prostate biopsy. For those who need biopsy, we are evaluating novel MRI-US fusion targeted biopsy, a technique that greatly improves upon the conventional biopsy method.
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Justin L. Sonnenburg
Alex and Susie Algard Endowed Professor
Current Research and Scholarly InterestsThe goals of the Sonnenburg Lab research program are to (i) elucidate the basic mechanisms that underlie dynamics within the gut microbiota and (ii) devise and implement strategies to prevent and treat disease in humans via the gut microbiota. We investigate the principles that govern gut microbial community function and interaction with the host using a broad range of experimental approaches including studies of microbiomes in diverse human cohorts.
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Andrew Spakowitz
Senior Associate Dean for Research and Faculty Affairs, Professor of Chemical Engineering, of Materials Science and Engineering and, by courtesy, of Applied Physics
Current Research and Scholarly InterestsTheory and computation of biological processes and complex materials
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Sean Paul Spencer, MD,PhD
Assistant Professor of Medicine (Gastroenterology and Hepatology)
BioSean Spencer, MD,PhD is a Gastroenterologist and Physician Scientist at Stanford University working with Justin Sonennburg,PhD to uncover the role of dietary intake on the gut microbiome and mucosal immune system. Sean obtained his medical degree University of Pennsylvania, earning his PhD studying nutritional immunology with Yasmine Belkaid,PhD at the National Institutes of Health (NIH), after which he moved to Boston for residency training at Massachusetts General Hospital and completed his Gastroenterology training at Stanford University. Sean’s career goal is to study mechanisms by which dietary intake influences our microbiome and immune system to better understand and treat gastrointestinal disease. Sean has launched a microbiome-focused clinical practice at Stanford where he is working to develop novel microbiome diagnostics and microbial medicines.
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Erik Sperling
Associate Professor of Earth and Planetary Sciences, Senior Fellow at the Woods Institute for the Environment and Associate Professor, by courtesy, of Oceans
Current Research and Scholarly InterestsThe research interests in the Sperling Lab are Earth history and the evolution of life, and the interactions between the biosphere and the geosphere. As such this research can generally be considered paleontology, insofar as paleontology encompasses all aspects of the history of life.
Consequently, we define our research agenda by the questions we are interested in, rather than the tools used. This research incorporates multiple lines of evidence, and multiple tools, to investigate questions in the history of life. These lines of evidence include fossil data, molecular phylogenetics, sedimentary geochemistry, and developmental and ecological data from modern organisms. Ultimately, the goal is to link environmental change with organismal and ecological response through the lens of physiology.
Our field research takes place all over the world--current areas include:
-NW Canada (Yukon and Northwest Territories): Research has been conducted on the early Neoproterozoic Fifteenmile Group, Cryogenian and Ediacaran Windermere Supergroup, and on the Ordovician-Devonian Road River Group in the southern Richardson Mountains
-Southern Canadian Cordillera: Work here has focused on the early Cambrian Mural Formation and its soft-bodied fauna.
-England and Wales: Cambrian-Silurian successions in the Welsh Basin
-Namibia: Ediacaran Nama Group
-Upwelling zones: We study the oxygen minimum zone offshore California as an analogue for ancient low-oxygen oceans. -
David Spiegel
Jack, Lulu and Sam Willson Professor of Medicine
On Partial Leave from 10/01/2025 To 05/15/2026Current Research and Scholarly InterestsDr. Spiegel's research program involves mind/body interactions, including cancer progression, the response to traumatic stress, and the effect of hypnosis on the perception of pain and anxiety.
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Edda Spiekerkoetter
Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsPulmonary Arterial Hypertension
Pulmonary Vascular Remodeling
Modulation of BMPR, ENG, ACVRL1 (ALK1), SMAD signaling
Structural and molecular programs governing right ventricular adaptation and failure
Hereditary Hemorrhagic Telangiectasia
Pulmonary Arteriovenous malformations
Computational Drug Prediction and Repurposing
Deep Tissue Confocal Imaging -
Daniel Spielman
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsMy research interests are in the field of medical imaging, particularly magnetic resonance imaging and in vivo spectroscopy. Current projects include MRI and MRS at high magnetic fields and metabolic imaging using hyperpolarized 13C-labeled MRS.
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Alfred M. Spormann
Professor of Civil and Environmental Engineering and of Chemical Engineering, Emeritus
Current Research and Scholarly InterestsMetabolism of anaerobic microbes in diseases, bioenergy, and bioremediation
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James Spudich
Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Emeritus
Current Research and Scholarly InterestsThe general research interest of this laboratory is the molecular basis of cell motility, with a current emphasis on power output by the human heart. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement, changes in cell shape and muscle contraction.
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Randall Stafford
Professor of Medicine (Stanford Prevention Research Center)
Current Research and Scholarly InterestsAs Director of the SPRC Program on Prevention Outcomes and Practices, my work focuses on cardiovascular disease treatment and prevention, the adoption of new technology and practices, and patterns of physician practice, particularly medication prescribing. Specific interests include measuring and improving the quality of outpatient care, disparities in health care by race, gender, age and socioeconomic status, and interventions to improve prevention outcomes.
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Konstantina M. Stankovic, MD, PhD, FACS
Bertarelli Foundation Professor and Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsOur investigative efforts are organized along 3 research thrusts:
1. Vestibular schwannoma: uncovering mechanisms of sensorineural hearing loss (SNHL) and identifying better therapies;
2. High-resolution imaging of the inner ear;
3. Novel sensing of and therapies for SNHL.
Considering the complex and multifaceted nature of these challenges, our approach entails tailored solutions that integrate techniques from molecular biology, systems neuroscience, biotechnology, and otologic surgery. -
Creed Stary
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (MSD) and, by courtesy, of Ophthalmology
On Partial Leave from 06/01/2025 To 03/31/2026Current Research and Scholarly InterestsMechanisms promoting neuronal survival following cerebral ischemia-reperfusion injury; utilizing microRNA's to target multiple pathways to promote mitochondrial homeostasis and cell survival; anesthetic neurotoxicity; astrocyte-neuronal interaction
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Kristan Staudenmayer, MD, MS, FACS
Associate Professor of Surgery (General Surgery)
Current Research and Scholarly InterestsDefining the Impact of Injuries in the Elderly
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Tim Stearns
Professor of Biology, Emeritus
Current Research and Scholarly InterestsWe use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How do the centrosome and cilium control cell control cell signaling? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?
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Gary K. Steinberg, MD, PhD
Bernard and Ronni Lacroute-William Randolph Hearst Professor of Neurosurgery and Neurosciences and Professor, by courtesy, of Neurology and Neurological Sciences
Current Research and Scholarly InterestsOur laboratory investigates the pathophysiology and treatment of cerebral ischemia, and methods to restore neurologic function after stroke. Treatment strategies include brain hypothermia, stem cell transplantation and optogenetic stimulation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease, as well as stem cell transplant.
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Lawrence Steinman, MD
George A. Zimmermann Professor and Professor of Pediatrics
Current Research and Scholarly InterestsOur laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis. We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab. We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids. We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis.
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Lars Steinmetz
Dieter Schwarz Foundation Endowed Professor
Current Research and Scholarly InterestsThe Steinmetz lab develops genomic technologies to study the genetic basis of complex phenotypes, the mechanisms of gene regulation, and the molecular systems underpinning disease. We’re leveraging biological insights across scales and organisms to predict, diagnose, treat and ultimately prevent disease.
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David A. Stevens
Professor of Medicine, Emeritus
Current Research and Scholarly InterestsImmunology and chemotherapy of human fungal diseases, particularly coccidioidomycosis (Valley Fever) in California and aspergillosis, and the parasitic disease, trypanosomiasis.
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David Stevenson
Professor of Pediatrics (Genetics)
Current Research and Scholarly InterestsMy research focuses on disorders of the RAS/MAPK pathway (eg. NF1, Noonan, CFC, and Costello syndrome). I am working on understanding the impact of RAS signaling on the musculoskeletal system. I use genomic approaches to identify somatic events and modifiers in the RASopathies. I am also involved in identifying outcome measures for use in clinical trials for the associated orthopedic manifestations. Other areas of research involve vascular anomalies, Prader-Willi syndrome, and hypophosphatasia.
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David K. Stevenson, M.D.
Harold K. Faber Professor of Pediatrics and Professor, by courtesy, of Obstetrics and Gynecology and of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsOur research is focused on the study of the ontogeny and control of heme catabolism and bilirubin production in the developing neonate. A better understanding of the role of increased bilirubin production in neonatal jaundice and the prevention of hemolytic jaundice has remained an overall objective of our program. We are also study the causes of preterm birth and ways to prevent it.
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Eric Stice
Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
BioDr. Stice served as an assistant professor and associate professor at the University of Texas at Austin and as a Senior Research Scientist at Oregon Research Institute before joining the faculty at Stanford University. His research focuses on identifying risk factors that predict onset of eating disorders, obesity, substance abuse, and depression to advance knowledge regarding etiologic processes, including the use of functional neural imaging. He also designs, evaluates, and disseminates prevention and treatment interventions for eating disorders, obesity, and depression. For instance, he developed a dissonance-based eating disorder prevention program that has been implemented with over 6 million young girls in 140 countries. He has published 335 articles in high-impact outlets, including Science, Psychological Bulletin, Archives of General Biological Psychiatry, American Journal of Clinical Nutrition, and Journal of Neuroscience.
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Aaron F. Straight
Pfeiffer and Herold Families Professor, Professor of Biochemistry and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsWe study the biology of chromosomes. Our research is focused on understanding how chromosomal domains are specialized for unique functions in chromosome segregation, cell division and cell differentiation. We are particularly interested in the genetic and epigenetic processes that govern vertebrate centromere function, in the organization of the genome in the eukaryotic nucleus and in the roles of RNAs in the regulation of chromosome structure.
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Thomas Sudhof
Avram Goldstein Professor in the School of Medicine, Professor of Neurosurgery and, by courtesy, of Neurology and Neurological Sciences and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsInformation transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.
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Brian Suffoletto
Professor of Emergency Medicine (Adult Clinical/Academic)
Current Research and Scholarly InterestsDr. Suffoletto is an emergency physician and NIH-funded investigator with a focus on collecting novel forms of longitudinal and remote data to inform temporal risk prediction and inform just-in-time adaptive interventions
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Edith Vioni Sullivan
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsApplication of neuroimaging modalities and component process analysis of cognitive, sensory, and motor functions to identify brain structural and functional mechanisms disrupted in diseases affecting the brain: alcohol use disorder, HIV infection, dementia, and normal aging from adolescence to senescence.
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Wenfei Sun
Assistant Professor of Medicine (Endocrinology)
Current Research and Scholarly InterestsWe explore neural circuits regulating memory and systemic metabolism, integrating neuroscience and metabolic biology to tackle cognitive decline and metabolic disorders.
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Yang Sun, MD, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsWe are interested in the role of inositol phosphatases in eye development and disease, using both animal models and human disease tissue. We are a translational laboratory seeking to understand the basic function of proteins as well as developing therapeutic strategies for clinical trials.
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Zijie Sun
Professor of Urology, Emeritus
Current Research and Scholarly InterestsWe focus on understanding the molecular mechanism of transcription factors that govern the transformation of normal cells to a neoplastic state. We are especially interested in nuclear hormone action and its interactions with other signaling pathways in tumor development and progression.
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John B. Sunwoo, MD
Edward C. and Amy H. Sewall Professor in the School of Medicine and Professor, by courtesy, of Dermatology
Current Research and Scholarly InterestsMy laboratory is focused on two primary areas of research: (1) the immune response to head and neck cancer and to a tumorigenic population of cells within these malignancies called cancer stem cells; (2) the developmental programs of a special lymphocyte population involved in innate immunity called natural killer (NK) cells; and (3) intra-tumor and inter-tumor heterogeneity.
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Trisha Suppes, MD, PhD
Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
Current Research and Scholarly InterestsLong-term treatment strategies for bipolar disorder, treatment for bipolar II disorder, use of treatment algorithms, and treatment of major depression.
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Yuri Suzuki
Stanley G. Wojcicki Professor, Professor of Applied Physics, and by courtesy, of Materials Science and Engineering
Current Research and Scholarly InterestsHer interests are focused on novel ground states and functional properties in condensed matter systems synthesized via atomically precise thin film deposition techniques with a recent emphasis has been on highly correlated electronic systems:
• Emergent interfacial electronic & magnetic phenomena through complex oxide heteroepitaxy
• Low dimensional electron gas systems
• Spin current generation, propagation and control in complex oxide-based ferromagnets
• Multifunctional behavior in complex oxide thin films and heterostructures -
Katrin J Svensson
Associate Professor of Pathology
Current Research and Scholarly InterestsMolecular metabolism
Protein biochemistry
Cell biology and function
Animal physiology -
James Swartz
James H. Clark Professor in the School of Engineering and Professor of Chemical Engineering and of Bioengineering
Current Research and Scholarly InterestsProgram Overview
The world we enjoy, including the oxygen we breathe, has been beneficially created by biological systems. Consequently, we believe that innovative biotechnologies can also serve to help correct a natural world that non-natural technologies have pushed out of balance. We must work together to provide a sustainable world system capable of equitably improving the lives of over 10 billion people.
Toward that objective, our program focuses on human health as well as planet health. To address particularly difficult challenges, we seek to synergistically combine: 1) the design and evolution of complex protein-based nanoparticles and enzymatic systems with 2) innovative, uniquely capable cell-free production technologies.
To advance human health we focus on: a) achieving the 120 year-old dream of producing “magic bullets”; smart nanoparticles that deliver therapeutics or genetic therapies only to specific cells in our bodies; b) precisely designing and efficiently producing vaccines that mimic viruses to stimulate safe and protective immune responses; and c) providing a rapid point-of-care liquid biopsy that will count and harvest circulating tumor cells.
To address planet health we are pursuing biotechnologies to: a) inexpensively use atmospheric CO2 to produce commodity biochemicals as the basis for a new carbon negative chemical industry, and b) mitigate the intermittency challenges of photovoltaic and wind produced electricity by producing hydrogen either from biomass sugars or directly from sunlight.
More than 25 years ago, Professor Swartz began his pioneering work to develop cell-free biotechnologies. The new ability to precisely focus biological systems toward efficiently addressing new, “non-natural” objectives has proven tremendously useful as we seek to address the crucial and very difficult challenges listed above. Another critical feature of the program is the courage (or naivete) to approach important objectives that require the development and integration of several necessary-but- not-sufficient technology advances. -
Karl G. Sylvester
Professor of Surgery (Pediatric Surgery)
Current Research and Scholarly InterestsScholarly interests include investigation of molecular markers of human disease that provide diagnostic function, serve as targets for possible therapeutic manipulation, or provide insight into mechanisms of human disease. Specific diseases of interest include common conditions of pregnancy, gut microbial ecology and Necrotizing Enterocolitis (NEC).
