School of Medicine
Showing 11,801-11,900 of 12,313 Results
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Sean M. Wu
Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMy lab seeks to identify mechanisms regulating cardiac lineage commitment during embryonic development and the biology of cardiac progenitor cells in development and disease. We believe that by understanding the transcriptional and epigenetic basis of cardiomyocyte growth and differentiation, we can identify the most effective ways to repair diseased adult hearts. We employ mouse and human embryonic and induced pluripotent stem cells as well as rodents as our in vivo models for investigation.
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Timothy Ting-Hsuan Wu
MD Student, expected graduation Spring 2023
Ph.D. Student in Biochemistry, admitted Summer 2021
Temp Employee, Medicine - Med/Pulmonary, Allergy & Critical Care MedicineCurrent Research and Scholarly InterestsMolecular and cellular basis of lung development, renewal and disease;
Single cell analysis of SARS-CoV-2 lung infection;
Vascular inflammation and immune dysregulation in pulmonary hypertension. -
Xiaokang Wu
Postdoctoral Scholar, Cardiovascular Institute
BioDr. Wu earned her medical degree and a doctorate in clinical medicine at the West China Medical College in China. She received her first postdoc training at Smidt heart institute of Cedars Sinai medical center and focused on studying the endovascular inflammation and calcium regulation in HFpEF (Heart Failure with Preserved Ejection Fraction) and testing the efficacy of Cardiosphere-derived cells (CDCs) and their secreted exosomes (CDCexo) for heart failure. She comes to the Alexander Lab with expertise in calcium handling and cardiosphere-derived cell-based therapy in rodents models. Dr. Wu is currently leading our research efforts on studying the mechanisms underlying the development of transthyretin cardiac amyloidosis(ATTR). Her work using iPSC and animal models as well as human samples will undoubtedly lead to important insights into this deadly disease and improve outcomes for cardiac amyloid patients.
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Yufan (Fred) Wu
Affiliate, Dean's Office Operations - Dean Other
Resident in Radiation Oncology - Radiation TherapyCurrent Research and Scholarly InterestsPeer review:
- International Journal of Radiation Oncology, Biology, Physics (Red Journal) resident peer reviewer
- Ad hoc reviewer for journal manuscripts, Muscle & Nerve Journal
- Peer reviewer for conference abstracts, UCSF Department of Family & Community Medicine Rodnick Colloquium
Google Scholar profile (list of publications):
https://scholar.google.com/citations?hl=en&user=scgY1ecAAAAJ -
Courtney Wusthoff, MD
Associate Professor of Neurology and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly InterestsMy projects focus on clinical research in newborns with, or at risk, for brain injury. I use EEG in at-risk neonates to better understand the underlying pathophysiology of risk factors that may lead to worse outcomes. I am particularly interested in neonatal seizures and how they may exacerbate perinatal brain injury with a goal to identify treatments that might protect the vulnerable brain. I am also interested in EEG in other pediatric populations, as well as medical ethics and global health.
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Joanna Wysocka
Lorry Lokey Professor and Professor of Developmental Biology
Current Research and Scholarly InterestsThe precise and robust regulation of gene expression is a cornerstone for complex biological life. Research in our laboratory is focused on understanding how regulatory information encoded by the genome is integrated with the transcriptional machinery and chromatin context to allow for emergence of form and function during human embryogenesis and evolution, and how perturbations in this process lead to disease.
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Tony Wyss-Coray, PhD
D. H. Chen Professor II
Current Research and Scholarly InterestsUse of genetic and molecular tools to dissect immune and inflammatory pathways in Alzheimer's and neurodegeneration.
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Zhen Xiao
Postdoctoral Scholar, Molecular Imaging Program at Stanford
Current Research and Scholarly InterestsApplying magnetic nanomaterials for bioimaging and cancer treatment
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Feng Xie
Postdoctoral Scholar, Anesthesiology, Perioperative and Pain Medicine
BioFeng Xie is currently a postdoctoral scholar at Stanford University School of Medicine, and he recently graduated with a joint Ph.D. degree from Duke University and the National University of Singapore. He previously obtained his bachelor’s degree from Tsinghua University, Beijing, China, in 2017. During his Ph.D. study, he utilized interpretable machine learning tools in acute and emergency care settings and published six first-author research papers in high-impact journals. Specifically, he developed a novel informatics framework called AutoScore, which automatically generates interpretable clinical scores from electronic health records. This open-source software package has been used by local and international researchers, downloaded about 400 times per month from the CRAN platform, and the first paper published in 2020 has garnered around 40 citations. His research interests include machine learning, clinical informatics and decision-making, predictive models, electronic health records, and risk stratification in acute care settings.
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James Xie
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioDr. James Xie is a pediatrician and pediatric anesthesiologist at Stanford University School of Medicine. His goal is to improve patient care with health information technologies. Currently he is a clinical informatics physician (CI-MD) and Epic physician builder at Stanford Children's Health.
Dr. Xie studied computer science and medicine at Stanford University, followed by a combined residency in general pediatrics at Boston Children's Hospital and Boston Medical Center and anesthesiology at Brigham and Women's Hospital. After residency, he completed a fellowship in pediatric anesthesiology at Stanford Children's Health where he subsequently joined the faculty as a Clinical Assistant Professor. -
Lei Xing
Jacob Haimson and Sarah S. Donaldson Professor and Professor, by courtesy, of Electrical Engineering
Current Research and Scholarly Interestsartificial intelligence in medicine, medical imaging, Image-guided intervention, molecular imaging, biology guided radiation therapy (BGRT), treatment plan optimization
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Jian Xiong
Postdoctoral Scholar, Chemical Engineering
BioI thrive to understand the roles of lysosomes in physiological and pathological conditions. Lysosomes are both degradation compartment and metabolic controlling hub, and dysregulation of lysosomal functions are frequently implicated in a vast number of diseases including neurodegenerative diseases, however, the systematic knowledge of the molecular mechanism by which lysosomal contributes to these diseases is lacking. Ion channels are the primary mediators of neuronal activity, defects in neuronal ion channel activity are linked with many kinds of neurodegenerative diseases. Interestingly, besides typical ion channels that are involved in the neuronal activity, defects in lysosomal ion channels, such as TRPML1, CLN7 and CLC-7 are also implicated in neuropathy. My previous work as Ph.D student in University of Texas MD Anderson Cancer Center focused on regulation of lysosomal function by ion channels and metabolites. I discovered a mechanism of lysosomal Na+ channel regulate mTORC1 activation by regulating lysosomal amino acid accumulation. I also discovered role of glutamine in controlling lysosomal degradation capacity. In the meantime, I developed novel methods to isolate organelles. My ultimate research goal is to understand the key developmental pathways and how alterations in gene sequences and expression contribute to human disease, therefore, I am pursuing independent academic researcher as my career goal. Starting Feb 2022, I work with Dr. Monther Abu-Remaileh at Stanford University on role of lysosomes in neurodegenerative diseases. I use genetics, chemical biology and omics approaches to study lysosome function under various physiological and pathological conditions, especially age-associated neurodegenerative disorders, and monogenic neurodegenerative lysosome storage diseases. In Stanford, I aim to integrate ionic regulation, metabolomic regulation and functional proteomic regulation to systematically understand the biology of lysosome in physiological conditions and pathological conditions.
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Adam Z. Xu
Affiliate, Ophthalmology Research/Clinical Trials
BioStudying retinal ganglion cell (RGC) neuroprotection & axon regeneration with the Hu Lab, https://med.stanford.edu/hulab.html
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Shiqin Xu
Masters Student in Clinical Informatics Management, admitted Summer 2022
Senior Manager, Courses and Global Programs, School of Medicine - MDRP'S - Biodesign ProgramCurrent Role at StanfordSenior Manager, Courses and Global Programs, Stanford Biodesign
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Shin Yajima
Postdoctoral Scholar, Cardiothoracic Surgery
BioI am a board-certified cardiothoracic surgeon in Japan. Throughout my clinical experience and research, I realized that insufficient myocardial blood flow had little impact on myocardial functional recovery because percutaneous coronary intervention or coronary artery bypass grafting (CABG) could approach and supply blood flow to the superficial large coronary arteries, but not to intramyocardial microvascular arteries, especially where microvasculature was scarce or absent. Moreover, myocardial ischemia-reperfusion (I/R) impaired cardiac functional recovery in ischemic hearts, including transplanted hearts. As a result, my research interests include myocardial microvascular dysfunction and myocardial I/R injury.
During my Ph.D. studies in cardiovascular surgery, I focused on a prostacyclin analog that inhibits thromboxane A2 synthase and promotes angiogenesis and restores myocardial blood flow via proangiogenic and vasodilatory effects. Direct epicardial placement of a microform of this compound in a porcine ischemia cardiomyopathy model resulted in enhanced myocardial angiogenesis and recovery of myocardial function. Then, I developed nanoparticles (NPs) that contained this compound, which I applied to a rat ischemia myocardial reperfusion model with intravenous injection to demonstrate attenuated myocardial I/R injury with selective accumulation in the ischemic myocardium, better-preserved capillary networks, better-preserved myocardial blood flow, and a smaller infarct size. Using induced pluripotent stem cells (iPSCs) and adipose-derived mesenchymal stem cells, I have also worked on tissue engineering for myocardial regeneration. With direct implantation of cardiomyocyte sheets derived from human iPSCs onto ischemic myocardial tissue, we elucidated myocardial regeneration through thickened myocardial tissue, proangiogenic effects, improved cardiac performance, and reduced left ventricular remodeling in both small and large animals. These works have already been published (representative examples are provided below), and I have received a number of academic honors and research grants (ongoing research support; Japan Heart Foundation/Bayer Research Grant Abroad, 01/01/2022 - 12/31/2022).
My career goal is to attain leadership in academic cardiovascular surgery. During my postdoctoral fellowship, I intend to create novel therapeutic methods to improve the outcomes of ischemic heart disease through engineering analysis and the development of innovative solutions. My mentor, Dr. Woo, is a distinguished mentor with a stellar reputation for training academic surgeons, and Stanford University provides extraordinary research resources. I feel extremely fortunate to have such an ideal environment in which to carry out this project and continue bioengineering's advancement of cardiothoracic surgery. -
Yasuaki Yanagawa
Postdoctoral Scholar, Infectious Diseases
BioRNAseq for Entaoeba histolytica
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Fan Yang
Associate Professor of Orthopaedic Surgery and of Bioengineering
Current Research and Scholarly InterestsOur research seeks to understand how microenvironmental cues regulate stem cell fate, and to develop novel biomaterials and stem cell-based therapeutics for tissue engineering and regenerative medicine. Our work spans from fundamental science, technology development, to translational research.We are particularly interested in developing better therapies for treating musculoskeletal diseases, cardiovascular diseases and cancer.
