Bio-X
Showing 201-300 of 1,063 Results
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Martha S. Cyert
Dr. Nancy Chang Professor
Current Research and Scholarly InterestsThe Cyert lab is identifying signaling networks for calcineurin, the conserved Ca2+/calmodulin-dependent phosphatase, and target of immunosuppressants FK506 and cyclosporin A, in yeast and mammals. Cell biological investigations of target dephosphorylation reveal calcineurin’s many physiological functions. Roles for short linear peptide motifs, or SLiMs, in substrate recognition, network evolution, and regulation of calcineurin activity are being studied.
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Agnieszka Czechowicz, MD, PhD
Assistant Professor of Pediatrics (Stem Cell Transplantation)
Current Research and Scholarly InterestsDr. Czechowicz’s research is aimed at understanding how hematopoietic stem cells interact with their microenvironment in order to subsequently modulate these interactions to improve bone marrow transplantation and unlock biological secrets that further enable regenerative medicine broadly. This work can be applied across a variety of disease states ranging from rare genetic diseases, autoimmune diseases, solid organ transplantation, microbiome-augmentation and cancer.
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Jeremy Dahl
Associate Professor of Radiology (Pediatric Radiology)
Current Research and Scholarly InterestsUltrasonic beamforming, imaging methods, systems, and devices.
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Hongjie Dai
The J.G. Jackson and C.J. Wood Professor of Chemistry, Emeritus
BioProfessor Dai’s research spans chemistry, physics, and materials and biomedical sciences, leading to materials with properties useful in electronics, energy storage and biomedicine. Recent developments include near-infrared-II fluorescence imaging, ultra-sensitive diagnostic assays, a fast-charging aluminum battery and inexpensive electrocatalysts that split water into oxygen and hydrogen fuels.
Born in 1966 in Shaoyang, China, Hongjie Dai began his formal studies in physics at Tsinghua U. (B.S. 1989) and applied sciences at Columbia U. (M.S. 1991). He obtained his Ph.D. from Harvard U and performed postdoctoral research with Dr. Richard Smalley. He joined the Stanford faculty in 1997, and in 2007 was named Jackson–Wood Professor of Chemistry. Among many awards, he has been recognized with the ACS Pure Chemistry Award, APS McGroddy Prize for New Materials, Julius Springer Prize for Applied Physics and Materials Research Society Mid-Career Award. He has been elected to the American Academy of Arts and Sciences, National Academy of Sciences (NAS), National Academy of Medicine (NAM) and Foreign Member of Chinese Academy of Sciences.
The Dai Laboratory has advanced the synthesis and basic understanding of carbon nanomaterials and applications in nanoelectronics, nanomedicine, energy storage and electrocatalysis.
Nanomaterials
The Dai Lab pioneered some of the now-widespread uses of chemical vapor deposition for carbon nanotube (CNT) growth, including vertically aligned nanotubes and patterned growth of single-walled CNTs on wafer substrates, facilitating fundamental studies of their intrinsic properties. The group developed the synthesis of graphene nanoribbons, and of nanocrystals and nanoparticles on CNTs and graphene with controlled degrees of oxidation, producing a class of strongly coupled hybrid materials with advanced properties for electrochemistry, electrocatalysis and photocatalysis. The lab’s synthesis of a novel plasmonic gold film has enhanced near-infrared fluorescence up to 100-fold, enabling ultra-sensitive assays of disease biomarkers.
Nanoscale Physics and Electronics
High quality nanotubes from his group’s synthesis are widely used to investigate the electrical, mechanical, optical, electro-mechanical and thermal properties of quasi-one-dimensional systems. Lab members have studied ballistic electron transport in nanotubes and demonstrated nanotube-based nanosensors, Pd ohmic contacts and ballistic field effect transistors with integrated high-kappa dielectrics.
Nanomedicine and NIR-II Imaging
Advancing biological research with CNTs and nano-graphene, group members have developed π–π stacking non-covalent functionalization chemistry, molecular cellular delivery (drugs, proteins and siRNA), in vivo anti-cancer drug delivery and in vivo photothermal ablation of cancer. Using nanotubes as novel contrast agents, lab collaborations have developed in vitro and in vivo Raman, photoacoustic and fluorescence imaging. Lab members have exploited the physics of reduced light scattering in the near-infrared-II (1000-1700nm) window and pioneered NIR-II fluorescence imaging to increase tissue penetration depth in vivo. Video-rate NIR-II imaging can measure blood flow in single vessels in real time. The lab has developed novel NIR-II fluorescence agents, including CNTs, quantum dots, conjugated polymers and small organic dyes with promise for clinical translation.
Electrocatalysis and Batteries
The Dai group’s nanocarbon–inorganic particle hybrid materials have opened new directions in energy research. Advances include electrocatalysts for oxygen reduction and water splitting catalysts including NiFe layered-double-hydroxide for oxygen evolution. Recently, the group also demonstrated an aluminum ion battery with graphite cathodes and ionic liquid electrolytes, a substantial breakthrough in battery science. -
Heike Daldrup-Link
Professor of Radiology (General Radiology) and, by courtesy, of Pediatrics (Hematology/Oncology)
Current Research and Scholarly InterestsAs a physician-scientist involved in the care of pediatric patients and developing novel pediatric molecular imaging technologies, my goal is to link the fields of nanotechnology and medical imaging towards more efficient diagnoses and image-guided therapies. Our research team develops novel imaging techniques for improved cancer diagnosis, for image-guided-drug delivery and for in vivo monitoring of cell therapies in children and young adults.
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Ronald L. Dalman MD
Dr. Walter C. Chidester Professor
Current Research and Scholarly InterestsVascular biology, arterial remodeling, aneurysm development; innovative treatment strategies for AAA, animal models of arterial disease, arterial remodeling and flow changes in spinal cord injury, genetic regulation of arterial aneurysm formation
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Roxana Daneshjou, MD, PhD
Assistant Professor of Biomedical Data Science and of Dermatology
BioDr. Daneshjou studied Bioengineering at Rice University before matriculating to Stanford School of Medicine where she completed her MD and a PhD in Genetics with Dr. Russ Altman as part of the medical scientist training program. She completed dermatology residency at Stanford as part of the research track and completed a postdoc in Biomedical Data Science with Dr. James Zou. She currently is the assistant director of the Center of Excellence for Precision Heath & Pharmacogenomics, director of informatics for the Stanford Skin Innovation and Interventional Research Group (SIIRG), a founding member of the Translational AI in Dermatology (TRAIND) group, and a faculty affiliate of Human-centered Artificial Intelligence (HAI) and the AI in Medicine and Imaging (AIMI) centers.
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Bruce Daniel
Professor of Radiology (Body Imaging) and, by courtesy, of Bioengineering
Current Research and Scholarly Interests1. MRI of Breast Cancer, particularly new techniques. Currently being explored are techniques including ultra high spatial resolution MRI and contrast-agent-free detection of breast tumors.
2. MRI-guided interventions, especially MRI-compatible remote manipulation and haptics
3. Medical Mixed Reality. Currently being explored are methods of fusing patients and their images to potentially improve breast conserving surgery, and other conditions. -
Kyle Gabriel Daniels
Assistant Professor of Genetics
BioKyle obtained his BS in Biochemistry from the University of Maryland College Park in 2010, conducting undergraduate research with Dr. Dorothy Beckett, PhD. He obtained his PhD in Biochemistry with a certificate in Structural Biology and Biophysics. His dissertation is titled "Kinetics of Coupled Binding and Conformational Change in Proteins and RNA" and was completed in the laboratory of Dr. Terrence G. Oas, PhD. Kyle performed postdoctoral training with Dr. Wendell A. Lim, PhD at UCSF studying how CAR T cell phenotype is encoded by modular signaling motifs within chimeric antigen receptors.
Kyle's lab is interested in harnessing the principles of modularity to engineer receptors and gene circuits to control cell functions.
The lab will use synthetic biology, medium- and high-throughput screens, and machine learning to: (1) Engineer immune cells to achieve robust and durable responses against various cancer targets, (2) Coordinate behavior of multiple engineered cell types in cancer, autoimmune disease, and payload delivery, (3) Control survival, proliferation, and differentiation of hematopoietic stem cells (HSCs) and immune cells, and (4) Explore principles of modularity related to engineering receptors and gene circuits in mammalian cells. -
Gary Darmstadt
Professor (Teaching) of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology
Current Research and Scholarly InterestsI have extensive experience in the development of global health innovations and in working to test and scale-up health interventions. At Stanford University, I am playing a leading role in developing global women and children’s health research and educational programs, including the establishment of a Global Center for Gender Equality at Stanford University. My research focuses on advancing child health and development in low resource settings and advancing gender equality and health globally, and includes several applications of artificial intelligence. Before joining Stanford, I was Senior Fellow at the Bill & Melinda Gates Foundation (BMGF), where I led the development of initiatives to address gender inequalities and empower women and girls. Prior to this role, I served as the BMGF Director of Family Health, leading strategy development and implementation across maternal, newborn and child health, nutrition, and family planning. In this role, I was responsible for investments ranging from scientific discovery to intervention development and delivery of interventions at scale. I worked closely with the Discovery team to shape discovery and development investments and was a co-founder of the Saving Lives at Birth Development Grand Challenge, the Putting Women and Girls at the Center of Development Grand Challenge, and the Healthy Birth, Growth and Development initiative. Based on these experiences, I understand how to identify knowledge gaps and generate evidence of impact for new interventions, and how to utilize evidence to influence the policy dialogue leading to programmatic adoption and scale-up of interventions in low income settings. As Director of Family Health, I also co-led the development and implementation of the BMGF global health strategy for India, which cuts across multiple health and development sectors. Before joining BMGF, I was Associate Professor and Founding Director of the International Center for Advancing Neonatal Health in the Department of International Health at the Johns Hopkins Bloomberg School of Public Health. I led the development of newborn health research, including numerous facility- and community-based maternal and child health research trials. Before joining Johns Hopkins, I was Senior Research Advisor for the $50M Saving Newborn Lives program of Save the Children-US, where I led the development and implementation of the global research strategy for newborn health and survival.
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Eric Darve
Professor of Mechanical Engineering
Current Research and Scholarly InterestsThe research interests of Professor Darve span across several domains, including machine learning for engineering, surrogate and reduced order modeling, stochastic inversion, anomaly detection for engineering processes and manufacturing, numerical linear algebra, high-performance and parallel computing, and GPGPU.
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Rhiju Das
Professor of Biochemistry
Current Research and Scholarly InterestsOur lab seeks an agile and predictive understanding of how nucleic acids and proteins code for information processing in living systems. We develop new computational & chemical tools to enable the precise modeling, regulation, and design of RNA and RNA/protein machines.
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Rajesh Dash, MD PhD; Director of SSATHI & CardioClick
Associate Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsI have two research areas:
1) Heart disease in South Asians - genetic, metabolic, & behavioral underpinnings of an aggressive phenotype.
2) Imaging cell injury & recovery in the heart. Using Cardiac MRI to visualize signals of early injury and facilitating preventive medical therapy. Optimizing new imaging methods for viable cells to delineate live heart cells or transplanted stem cells. -
Laura M.K. Dassama
Assistant Professor of Chemistry and of Microbiology and Immunology
BioLaura Dassama is a chemical biologist who uses principles from chemistry and physics to understand complex biological phenomena, and to leverage that understanding for the modulation of biological processes. Her current research focuses on deciphering the molecular recognition mechanisms of multidrug transporters implicated in drug resistance, rational engineering and repurposing of natural products, and control of transcription factors relevant to sickle cell disease.
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Reinhold Dauskardt
Ruth G. and William K. Bowes Professor in the School of Engineering
BioDauskardt and his group have worked extensively on integrating new materials into emerging technologies including thin-film structures for nanoscience and energy technologies, high-performance composite and laminates for aerospace, and on biomaterials and soft tissues in bioengineering. His group has pioneered methods for characterizing adhesion and cohesion of thin films used extensively in device technologies. His research on wound healing has concentrated on establishing a biomechanics framework to quantify the mechanical stresses and biologic responses in healing wounds and define how the mechanical environment affects scar formation. Experimental studies are complimented with a range of multiscale computational capabilities. His research includes interaction with researchers nationally and internationally in academia, industry, and clinical practice.
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Jenna Davis
Associate Dean for Integrative Initiatives in Institutes and International Partnerships, Professor of Civil and Environmental Engineering, at the Stanford Doerr School of Sustainability and Higgins-Magid Senior Fellow at the Woods Institute
Current Research and Scholarly InterestsProfessor Davis’ research and teaching deals broadly with the role that water plays in promoting public health and economic development, with particular emphasis on low- and middle-income countries. Her group conducts applied research that utilizes theory and analytical methods from public and environmental health, engineering, microeconomics, and planning. They have conducted field research in more than 20 countries, most recently including Zambia, Bangladesh, and Kenya.
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Kara Davis
Assistant Professor of Pediatrics (Hematology/Oncology)
Current Research and Scholarly InterestsChildhood cancers can be considered aberrations of normal tissue development. We are interested in understanding childhood cancers through the lens of normal development. Further, individual tumors are composed of heterogeneous cell populations, not all cells being equal in their ability to respond to treatment or to repopulate a tumor. Thus, we take single cell approach to determine populations of clinical relevance.
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Mark M. Davis
Director, Stanford Institute for Immunity, Transplantation and Infection and the Burt and Marion Avery Family Professor
Current Research and Scholarly InterestsMolecular mechanisms of lymphocyte recognition and differentiation; Systems immunology and human immunology; vaccination and infection.
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Ronald W. Davis
Professor of Biochemistry and of Genetics
Current Research and Scholarly InterestsWe are using Saccharomyces cerevisiae and Human to conduct whole genome analysis projects. The yeast genome sequence has approximately 6,000 genes. We have made a set of haploid and diploid strains (21,000) containing a complete deletion of each gene. In order to facilitate whole genome analysis each deletion is molecularly tagged with a unique 20-mer DNA sequence. This sequence acts as a molecular bar code and makes it easy to identify the presence of each deletion.
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Vinicio de Jesus Perez MD
Associate Professor of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsMy work is aimed at understanding the molecular mechanisms involved in the development and progression of pulmonary arterial hypertension (PAH). I am interested in understanding the role that the BMP and Wnt pathways play in regulating functions of pulmonary endothelial and smooth muscle cells both in health and disease.
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Adam de la Zerda
Associate Professor of Structural Biology and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsMolecular imaging technologies for studying cancer biology in vivo
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Luis de Lecea
Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical and Translational Neurosciences Incubator)
Current Research and Scholarly InterestsMy lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction.
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Giulio De Leo
Professor of Oceans, of Earth System Science, Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy of Biology
Current Research and Scholarly InterestsI am a theoretical ecologist mostly interested in investigating factors and processes driving the dynamics of natural and harvested populations and on how to use this knowledge to inform practical management. I have worked broadly on life histories analysis, fishery management, dynamics and control of infectious diseases and environmental impact assessment.
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Karl Deisseroth
D. H. Chen Professor, Professor of Bioengineering and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsKarl Deisseroth's laboratory created and developed optogenetics, hydrogel-tissue chemistry (beginning with CLARITY), and a broad range of enabling methods. He also has employed his technologies to discover the neural cell types and connections that cause adaptive and maladaptive behaviors.
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Daniel James Delitto, MD, PhD, FACS
Assistant Professor of Surgery (General Surgery)
BioDr. Delitto is a board certified complex general surgical oncologist with a focus on conditions of the liver, pancreas, and stomach. He is an assistant professor in Stanford Medicine’s Department of Surgery.
His education includes a decade of postgraduate training in complex general surgical oncology, as well as a PhD in immunology with an emphasis on cancer biology. He completed a clinical fellowship at Johns Hopkins University and continued his research at the postdoctoral level in the laboratory of Dr. Elizabeth Jaffee. His research focus is on advancing the field of cancer immunology and harnessing his findings to improve immunotherapies.
He was the principal investigator of two studies examining the immune response to pancreatic cancer, including one funded by the National Cancer Institute.
Dr. Delitto has presented the findings of his research at conferences such as the American Association for Cancer Research, Society for the Immunotherapy of Cancer, American Association of Immunologists, American College of Surgeons, Academic Surgical Congress and Pancreas Club. In addition to cancer immunology, he has also presented work focused on cancer cachexia, surgical outcomes, translational experimental models and a variety of other oncologic topics.
He has published original work in Nature Communications, the Journal of the National Cancer Institute, Cancer Research, Clinical Cancer Research, and other high impact journals. He is also a reviewer for Annals of Surgery, Scientific Reports, Surgery, Tumor Biology, Journal of Surgical Research, PLOS ONE, and the Journal of Translational Medicine.
Dr. Delitto has earned numerous honors related to clinical excellence, teaching and research. He is board certified by the American Board of Surgery and a member of the Society of Surgical Oncology, American Association for Cancer Research and American Association of Immunologists. -
Scott L. Delp, Ph.D.
Director, Wu Tsai Human Performance Alliance at Stanford, James H. Clark Professor in the School of Engineering, Professor of Bioengineering, of Mechanical Engineering and, by courtesy, of Orthopaedic Surgery
Current Research and Scholarly InterestsExperimental and computational approaches to study human movement. Development of biomechanical models to analyze muscle function, study movement abnormalities, design medical products, and guide surgery. Imaging and health technology development. Discovering the principles of peak performance to advance human health. Human performance research. Wearable technologies, video motion capture, and machine learning to enable large-scale analysis.
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Utkan Demirci
Professor of Radiology (Canary Cancer Center) and, by courtesy, of Electrical Engineering
On Partial Leave from 02/26/2024 To 02/25/2025BioUtkan Demirci is a tenured professor in the School of Medicine at Stanford University and serves as the Interim Division Chief and Director of the Canary Center at Stanford for Cancer Early Detection in the Department of Radiology. Prior to Stanford, he was an Associate Professor of Medicine at the Brigham and Women’s Hospital, Harvard Medical School, and a faculty member of the Harvard-MIT Health Sciences and Technology division.
Professor Demirci received his PhD from Stanford University in Electrical Engineering in 2005 and holds M.S. degrees in Electrical Engineering, and in Management Science and Engineering. He has published over 200 peer-reviewed journal articles, 24 book chapters, 7 edited books, and several hundred abstracts and proceedings, as well as having over 25 patents and disclosures pending or granted. He has mentored and trained hundreds of successful scientists, entrepreneurs and academicians and fostered research and industry collaborations around the world. Dr. Demirci was awarded the NSF CAREER Award, and IEEE EMBS Early Career Award. He is currently a fellow of the the American Institute for Medical and Biological Engineering (AIMBE, 2017), and Distinguished Investigator of the Academy for Radiology and Biomedical Imaging Research and serves as an editorial board member for a number of peer-reviewed journals.
The BAMM Lab group focuses on developing innovative extracellular vesicle isolation tools, point-of-care technologies and creating microfluidic platforms for early cancer detection with broad applications to multiple diseases including infertility and HIV. Dr. Demirci’s lab has collaborated with over 50 research groups and industry partners around the world. His seminal work in microfluidics has led to the development of innovative FDA-approved platform technologies in medicine and many of his inventions have been industry licensed. He holds several FDA-approved and CE-marked technologies that have been widely used by fertility clinics with assisted reproductive technologies leading to over thousands of live births globally and in the US.
Dr. Demirci is a serial academic entrepreneur and co-founder of DxNow, Zymot, Levitas Bio, Mercury Biosciences and Koek Biotech and serves as an advisor, consultant and/or board member to some early stage companies and investment groups. -
Tushar Desai
Professor of Medicine (Pulmonary, Allergy and Critical Care Medicine)
Current Research and Scholarly InterestsBasic and translational research in lung stem cell biology, cancer, pulmonary fibrosis, COPD, and acute lung injury/ARDS. Upper airway stem cell CRISPR gene correction followed by autologous stem cell transplantation to treat Cystic fibrosis. Using lung organoids and precision cut lung slice cultures of mouse and human lungs to study molecular regulation of lung stem cells. Using transgenic mice to visualize Wnt protein transmission from niche cell to stem cell in vivo.
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Joseph M. DeSimone
Sanjiv Sam Gambhir Professor of Translational Medicine, Professor of Chemical Engineering and, by courtesy, of Chemistry, of Materials Science and Engineering, and of Operations, Information and Technology at the Graduate School of Business
BioJoseph M. DeSimone is the Sanjiv Sam Gambhir Professor of Translational Medicine and Chemical Engineering at Stanford University. He holds appointments in the Departments of Radiology and Chemical Engineering with courtesy appointments in the Department of Chemistry and in Stanford’s Graduate School of Business.
The DeSimone laboratory's research efforts are focused on developing innovative, interdisciplinary solutions to complex problems centered around advanced polymer 3D fabrication methods. In Chemical Engineering and Materials Science, the lab is pursuing new capabilities in digital 3D printing, as well as the synthesis of new polymers for use in advanced additive technologies. In Translational Medicine, research is focused on exploiting 3D digital fabrication tools to engineer new vaccine platforms, enhanced drug delivery approaches, and improved medical devices for numerous conditions, with a current major focus in pediatrics. Complementing these research areas, the DeSimone group has a third focus in Entrepreneurship, Digital Transformation, and Manufacturing.
Before joining Stanford in 2020, DeSimone was a professor of chemistry at the University of North Carolina at Chapel Hill and of chemical engineering at North Carolina State University. He is also Co-founder, Board Chair, and former CEO (2014 - 2019) of the additive manufacturing company, Carbon. DeSimone is responsible for numerous breakthroughs in his career in areas including green chemistry, medical devices, nanomedicine, and 3D printing. He has published over 350 scientific articles and is a named inventor on over 200 issued patents. Additionally, he has mentored 80 students through Ph.D. completion in his career, half of whom are women and members of underrepresented groups in STEM.
In 2016 DeSimone was recognized by President Barack Obama with the National Medal of Technology and Innovation, the highest U.S. honor for achievement and leadership in advancing technological progress. He has received numerous other major awards in his career, including the U.S. Presidential Green Chemistry Challenge Award (1997); the American Chemical Society Award for Creative Invention (2005); the Lemelson-MIT Prize (2008); the NIH Director’s Pioneer Award (2009); the AAAS Mentor Award (2010); the Heinz Award for Technology, the Economy and Employment (2017); the Wilhelm Exner Medal (2019); the EY Entrepreneur of the Year Award (2019 U.S. Overall National Winner); and the Harvey Prize in Science and Technology (2020). He is one of only 25 individuals elected to all three branches of the U.S. National Academies (Sciences, Medicine, Engineering). DeSimone received his B.S. in Chemistry in 1986 from Ursinus College and his Ph.D. in Chemistry in 1990 from Virginia Tech. -
Maximilian Diehn, MD, PhD
Jack, Lulu, and Sam Willson Professor and Professor of Radiation Oncology (Radiation Therapy)
On Leave from 11/27/2023 To 08/30/2024Current Research and Scholarly InterestsMy laboratory focuses on two main areas: 1) cancer stem cell biology and 2) novel biomarkers for identifying the presence of malignant cells (diagnostic), predicting outcome (prognostic), and predicting response to therapy (predictive). Areas of study include cancers of the lung, breast, and gastrointestinal system. Clinically I specialize in the treatment of lung cancer and applications of stereotactic ablative radiotherapy and perform both prospective and retrospective clinical studies.
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David Dill
Donald E. Knuth Professor in the School of Engineering, Emeritus
Current Research and Scholarly InterestsSecure and reliable blockchain technology at Facebook.
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Jun Ding
Associate Professor of Neurosurgery and of Neurology
On Leave from 02/01/2024 To 07/31/2024Current Research and Scholarly InterestsNeural circuits of movement control in health and movement disorders
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José R. Dinneny
Professor of Biology
Current Research and Scholarly InterestsThe biology of root systems is governed by both micro-scale and systemic signaling that allows the plant to integrate these complex variables into growth and branching decisions that ultimately determine the efficiency resources are captured. Research in my lab is aimed at understanding the response of roots to water-limiting conditions and is exploring this process at different organizational scales from the individual cell type to the level of the whole plant.
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Jennifer Dionne
Associate Professor of Materials Science and Engineering, Senior Fellow at the Precourt Institute for Energy and Associate Professor, by courtesy, of Radiology
BioJennifer Dionne is the Senior Associate Vice Provost of Research Platforms/Shared Facilities and an Associate Professor of Materials Science and Engineering and of Radiology (by courtesy) at Stanford. Jen received her Ph.D. in Applied Physics at the California Institute of Technology, advised by Harry Atwater, and B.S. degrees in Physics and Systems & Electrical Engineering from Washington University in St. Louis. Prior to joining Stanford, she served as a postdoctoral researcher in Chemistry at Berkeley, advised by Paul Alivisatos. Jen's research develops nanophotonic methods to observe and control chemical and biological processes as they unfold with nanometer scale resolution, emphasizing critical challenges in global health and sustainability. Her work has been recognized with the Alan T. Waterman Award (2019), an NIH Director's New Innovator Award (2019), a Moore Inventor Fellowship (2017), the Materials Research Society Young Investigator Award (2017), Adolph Lomb Medal (2016), Sloan Foundation Fellowship (2015), and the Presidential Early Career Award for Scientists and Engineers (2014), and was featured on Oprah’s list of “50 Things that will make you say ‘Wow!'"
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Frederick M. Dirbas, MD
Associate Professor of Surgery (General Surgery)
Current Research and Scholarly InterestsCurrently collaborating with Dr's Aaron Newman and Michael Clarke to study cancer stem cells associated with triple negative breast cancer. Advancing studies of FLASH radiotherapy in preclinical models for potential future use in humans. Investigating preclinical use of high dose gaseous nitric oxide in the treatment of solid tumors.
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Elizabeth DiRenzo, PhD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Music
Current Research and Scholarly InterestsDr. Erickson DiRenzo's laboratory integrates research techniques from the basic and clinical sciences to improve the prevention and management of voice disorders.
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Scott Dixon
Associate Professor of Biology
Current Research and Scholarly InterestsMy lab is interested in the relationship between cell death and metabolism. Using techniques drawn from many disciplines my laboratory is investigating how perturbation of intracellular metabolic networks can result in novel forms of cell death, such as ferroptosis. We are interested in applying this knowledge to find new ways to treat diseases characterized by insufficient (e.g. cancer) or excessive (e.g. neurodegeneration) cell death.
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Benjamin Domingue
Associate Professor of Education and, by courtesy, of Sociology
Current Research and Scholarly InterestsI'm interested in models for psychological measurement and their uses alongside applied statistical projects of all kinds.
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Sebastian Doniach
Professor of Applied Physics and of Physics, Emeritus
Current Research and Scholarly InterestsStudy of changes in conformation of proteins and RNA using x-ray scattering
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Ron Dror
Cheriton Family Professor and Professor, by courtesy, of Structural Biology and of Molecular & Cellular Physiology
Current Research and Scholarly InterestsMy lab’s research focuses on computational biology, with an emphasis on 3D molecular structure. We combine two approaches: (1) Bottom-up: given the basic physics governing atomic interactions, use simulations to predict molecular behavior; (2) Top-down: given experimental data, use machine learning to predict molecular structures and properties. We collaborate closely with experimentalists and apply our methods to the discovery of safer, more effective drugs.
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David Drover
Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsField of clinical pharmacology. This involves analysis of what the body does to a drug (pharmacokinetics) and how exactly a specific drug affects the body (pharmacodynamics). His research starts at the level of new drug development with detailed analysis of the pharmacokinetics and pharmacodynamics of a medication.
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Shaul Druckmann
Associate Professor of Neurobiology, of Psychiatry and Behavioral Sciences and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsOur research goal is to understand how dynamics in neuronal circuits relate and constrain the representation of information and computations upon it. We adopt three synergistic strategies: First, we analyze neural circuit population recordings to better understand the relation between neural dynamics and behavior, Second, we theoretically explore the types of dynamics that could be associated with particular network computations. Third, we analyze the structural properties of neural circuits.
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Justin Du Bois
Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Chemical and Systems Biology
BioResearch and Scholarship
Research in the Du Bois laboratory spans reaction methods development, natural product synthesis, and chemical biology, and draws on expertise in molecular design, molecular recognition, and physical organic chemistry. An outstanding goal of our program has been to develop C–H bond functionalization processes as general methods for organic chemistry, and to demonstrate how such tools can impact the logic of chemical synthesis. A second area of interest focuses on the role of ion channels in electrical conduction and the specific involvement of channel subtypes in the sensation of pain. This work is enabled in part through the advent of small molecule modulators of channel function.
The Du Bois group has described new tactics for the selective conversion of saturated C–H to C–N and C–O bonds. These methods have general utility in synthesis, making possible the single-step incorporation of nitrogen and oxygen functional groups and thus simplifying the process of assembling complex molecules. To date, lab members have employed these versatile oxidation technologies to prepare natural products that include manzacidin A and C, agelastatin, tetrodotoxin, and saxitoxin. Detailed mechanistic studies of metal-catalyzed C–H functionalization reactions are performed in parallel with process development and chemical synthesis. These efforts ultimately give way to advances in catalyst design. A long-standing goal of this program is to identify robust catalyst systems that afford absolute control of reaction selectivity.
In a second program area, the Du Bois group is exploring voltage-gated ion channel structure and function using the tools of chemistry in combination with those of molecular biology, electrophysiology, microscopy and mass spectrometry. Much of this work has focused on studies of eukaryotic Na and Cl ion channels. The Du Bois lab is interested in understanding the biochemical mechanisms that underlie channel subtype regulation and how such processes may be altered following nerve injury. Small molecule toxins serve as lead compounds for the design of isoform-selective channel modulators, affinity reagents, and fluorescence imaging probes. Access to toxins and modified forms thereof (including saxitoxin, gonyautoxin, batrachotoxin, and veratridine) through de novo synthesis drives studies to elucidate toxin-receptor interactions and to develop new pharmacologic tools to study ion channel function in primary cells and murine pain models. -
Alfredo Dubra, PhD
Professor of Ophthalmology
Current Research and Scholarly InterestsOur lab seeks to help the early diagnosing and monitoring progression of ocular, vascular, neurodegenerative and systemic diseases through novel non-invasive optical ophthalmic imaging. We pursue this goal through a multidisciplinary approach that integrates optics, computer science, vision science, electrical engineering and other engineering disciplines.
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John Duchi
Associate Professor of Statistics, of Electrical Engineering and, by courtesy, of Computer Science
Current Research and Scholarly InterestsMy work spans statistical learning, optimization, information theory, and computation, with a few driving goals: 1. To discover statistical learning procedures that optimally trade between real-world resources while maintaining statistical efficiency. 2. To build efficient large-scale optimization methods that move beyond bespoke solutions to methods that robustly work. 3. To develop tools to assess and guarantee the validity of---and confidence we should have in---machine-learned systems.
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Rob Dunbar
W.M. Keck Professor in the School of Earth Sciences, Professor of Oceans, of Earth System Science and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsOcean processes, biogeochemistry, climatology/paleoclimatology, isotopic chemistry, ocean policy
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Laramie Duncan
Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)
Current Research and Scholarly InterestsWe study genetic and environmental effects on mental health. Much of our work is computational and it relies upon genetic data, collected from millions of individuals, from around the world. We use genetic approaches because the overall goal of the lab is to discover fundamental information about psychiatric disorders, and ultimately to build more rational approaches to classification, prevention, and treatment.
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Alexander Dunn
Associate Professor of Chemical Engineering
On Partial Leave from 04/01/2024 To 06/30/2024Current Research and Scholarly InterestsMy lab is deeply interested in uncovering the physical principles that underlie the construction of complex, multicellular animal life.
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James Dunn
Professor of Surgery (Pediatric Surgery) and, by courtesy, of Bioengineering
Current Research and Scholarly InterestsIntestinal lengthening for short bowel syndrome
Intestinal stem cell therapy for intestinal failure
Skin derived precursor cell therapy for enteric neuromuscular dysfunction
Intestinal tissue engineering -
Gozde Durmus
Assistant Professor (Research) of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly InterestsDr. Durmus' research focuses on applying micro/nano-technologies to investigate cellular heterogeneity for single-cell analysis and personalized medicine. At Stanford, she is developing platform technologies for sorting and monitoring cells at the single-cell resolution. This magnetic levitation-based technology is used for wide range of applications in medicine, such as, label-free detection of circulating tumor cells (CTCs) from blood; high-throughput drug screening; and rapid detection and monitoring of antibiotic resistance in real-time. During her PhD, she has engineered nanoparticles and nanostructured surfaces to decrease antibiotic-resistant infections.
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Elizabeth Egan
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsMalaria is a parasitic disease transmitted by mosquitos that is a leading cause of childhood mortality globally. Public health efforts to control malaria have historically been hampered by the rapid development of drug resistance. The goal of our research is to understand the molecular determinants of critical host-pathogen interactions in malaria, with a focus on the erythrocyte host cell. Our long-term goal is to develop novel approaches to prevent or treat malaria and improve child health.
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Johannes C. Eichstaedt
Assistant Professor (Research) of Psychology
Current Research and Scholarly InterestsWell-being: affect, life satisfaction, and purpose, and their individual and societal determinants (lifestyle factors and policies); traits: character strengths, personality, trust, and empathy
Mental and physical health: depression, stress, and anxiety; health psychology: heart disease and opioid addiction
Methods: Natural Language Processing & Large Language Models; data science and
visualization; longitudinal methods, machine learning, and psychological assessment through AI -
Shirit Einav
Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsOur basic research program focuses on understanding the roles of virus-host interactions in viral infection and disease pathogenesis via molecular and systems virology single cell approaches. This program is combined with translational efforts to apply this knowledge for the development of broad-spectrum host-centered antiviral approaches to combat emerging viral infections, including dengue, coronaviruses, encephalitic alphaviruses, and Ebola, and means to predict progression to severe disease.
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Drew Endy
Associate Professor of Bioengineering and Senior Fellow, by courtesy, at the Hoover Institution and at the Freeman Spogli Institute for International Studies
Current Research and Scholarly InterestsWe work to strengthen the foundations and expand the frontiers of synthetic biology. Our foundational work includes (i) advancing reliable reuse of bio-measurements and -materials via standards that enable coordination of labor, and (ii) developing and integrating measurement and modeling tools for representing and analyzing living matter at whole-cell scales. Our work beyond the frontiers of current practice includes (iii) bootstrapping biotechnology tools in unconventional organisms (e.g., mealworms, wood fungus, skin microbes), and (iv) exploring the limits of whole-genome recoding and building cells from scratch. We also support strategy and policy work related to bio-safety, security, economy, equity, justice, and leadership.
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Barbara Elizabeth Engelhardt
Professor (Research) of Biomedical Data Science and, by courtesy, of Statistics
BioBarbara E Engelhardt is a Senior Investigator at Gladstone Institutes and Professor at Stanford University in the Department of Biomedical Data Science. She received her B.S. (Symbolic Systems) and M.S. (Computer Science) from Stanford University and her PhD from UC Berkeley (EECS) advised my Prof. Michael I Jordan. She was a postdoctoral fellow with Prof. Matthew Stephens at the University of Chicago. She was an Assistant Professor at Duke University from 2011-2014, and an Assistant, Associate, and then Full Professor at Princeton University in Computer Science from 2014-2022. She has worked at Jet Propulsion Labs, Google Research, 23andMe, and Genomics plc. In her career, she received an NSF GRFP, the Google Anita Borg Scholarship, the SMBE Walter M. Fitch Prize (2004), a Sloan Faculty Fellowship, an NSF CAREER, and the ISCB Overton Prize (2021). Her research is focused on developing and applying models for structured biomedical data that capture patterns in the data, predict results of interventions to the system, assist with decision-making support, and prioritize experiments for design and engineering of biological systems.
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Edgar Engleman
Professor of Pathology and of Medicine (Immunology and Rheumatology)
Current Research and Scholarly InterestsDendritic cells, macrophages, NK cells and T cells; functional proteins and genes; immunotherapeutic approaches to cancer, autoimmune disease, neurodegenerative disease and metabolic disease.
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Jesse Engreitz
Assistant Professor of Genetics
Current Research and Scholarly InterestsRegulatory elements in the human genome harbor thousands of genetic risk variants for common diseases and could reveal targets for therapeutics — if only we could map the complex regulatory wiring that connects 2 million regulatory elements with 21,000 genes in thousands of cell types in the human body.
We combine experimental and computational genomics, biochemistry, molecular biology, and genetics to assemble regulatory maps of the human genome and uncover biological mechanisms of disease. -
Daniel Bruce Ennis
Professor of Radiology (Veterans Affairs)
BioDaniel Ennis {he/him} is a Professor in the Department of Radiology. As an MRI scientist for nearly twenty years, he has worked to develop advanced translational cardiovascular MRI methods for quantitatively assessing structure, function, flow, and remodeling in both adult and pediatric populations. He began his research career as a Ph.D. student in the Department of Biomedical Engineering at Johns Hopkins University during which time he formed an active collaboration with investigators in the Laboratory of Cardiac Energetics at the National Heart, Lung, and Blood Institute (NIH/NHLBI). Thereafter, he joined the Departments of Radiological Sciences and Cardiothoracic Surgery at Stanford University as a postdoc and began to establish an independent research program with an NIH K99/R00 award focused on “Myocardial Structure, Function, and Remodeling in Mitral Regurgitation.” For ten years he led a group of clinicians and scientists at UCLA working to develop and evaluate advanced cardiovascular MRI exams as PI of several NIH funded studies. In 2018 he returned to the Department of Radiology at Stanford University as faculty in the Radiological Sciences Lab to bolster programs in cardiovascular MRI. He is also the Director of Radiology Research for the Veterans Administration Palo Alto Health Care System where he oversees a growing radiology research program.
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Gregory Enns
Professor of Pediatrics (Genetics)
Current Research and Scholarly Interestsmitochondrial genomics, lysosomal disorders, tandem-mass spectrometry newborn screening, and inborn errors of metabolism presentations and natural history
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Neir Eshel, MD, PhD
Assistant Professor of Psychiatry and Behavioral Sciences (Major Laboratories & Clinical Translational Neurosciences Incubator)
BioDr. Eshel (he/him/his) is a tenure-track Assistant Professor in the Department of Psychiatry & Behavioral Sciences at Stanford University School of Medicine.
His clinical focus is the full-spectrum mental health care of sexual and gender minorities, with particular interest in depression, anxiety, and the complex effects of trauma in this population. He works in collaboration with other primary care and mental health providers at the Stanford LGBTQ+ program.
His research interests (www.staarlab.com) include the use of optogenetic, electrophysiological, neuroimaging, and behavioral approaches to probe the neural circuits of reward processing, decision making, and social behavior. He has won multi-year grants from the National Institutes of Health, Burroughs-Wellcome Fund, Brain and Behavior Research Foundation, and Simons Foundation to further his research.
Dr. Eshel has published articles on dopamine and motivation, the neuroscience of irritability, LGBTQ health, reward and punishment processing in depression, behavioral predictors of substance use among adolescents, and the mechanism of transcranial magnetic stimulation. His work has appeared in Nature, Science, Neuron, Nature Neuroscience, Annual Review of Neuroscience, JAMA, JAMA Psychiatry, Neuropsychopharmacology, Proceedings of the National Academy of Sciences, and Journal of Neuroscience. He is a co-inventor on a patent pending for a new class of drugs for addiction, and also the author of the book Learning: The Science Inside, a publication of the American Association for the Advancement of Science.
He has delivered presentations on the neural circuits of motivated behavior, anger expression in patients with PTSD, how dopamine facilitates learning, and LGBTQ-related topics at departmental seminars in London, Zurich, and Tel Aviv, and at the meetings of the American College of Neuropsychopharmacology, Society of Biological Psychiatry, and Association of American Medical Colleges, among others. He is also an associate editor of the Journal of Gay and Lesbian Mental Health, and an ad-hoc reviewer for numerous publications including Nature, Science, JAMA Psychiatry, Biological Psychiatry, and Current Biology.
Dr. Eshel has won honors for his scholarship and advocacy, including the Marshall Scholarship, the Outstanding Resident Award from the National Institute of Mental Health, the Science and SciLifeLab Grand Prize for Young Scientists, the Freedman Award (honorable mention) from the Brain and Behavior Research Foundation, the Polymath Award from Stanford's psychiatry department, and the National LGBT Health Achievement Award.
He is a member of the American Psychiatric Association, American College of Neuropsychopharmacology, Society of Biological Psychiatry, Association of Gay & Lesbian Psychiatrists, Society for Neuroscience, and other professional associations. He is also an advocate for LGBTQ rights, recently serving as the chair of Stanford's LGBTQ+ Benefits Advocacy Committee.
Prior to Stanford, Dr. Eshel trained and conducted research at the National Institutes of Health, Princeton University, the World Health Organization, University College London, and Harvard University. -
Carlos O. Esquivel, M.D., Ph.D.,FACS
Arnold and Barbara Silverman Professor in Pediatric Transplantation and Professor of Surgery (Abdominal Transplantation) and of Pediatrics (Gastroenterology, Hepatology and Nutrition)
Current Research and Scholarly Interests1) Induction of immunotolerance
2) Rejection of liver and intestinal transplantation.
3) Clinical outcomes of children with unresectable liver tumors. -
Ryann Fame
Assistant Professor of Neurosurgery
Current Research and Scholarly InterestsEarly neural progenitors respond to extrinsic cues that maintain and support their potency. These stem/ progenitor cells are in direct contact with the cerebrospinal fluid (CSF), which acts as part of their niche. Our research program encompasses the early neural stem cell niche, neural tube closure, CSF, metabolism, and cortical neuronal development. We are dedicated to broad collaboration focused on translating an understanding of neurodevelopment and CSF biology into regenerative strategies.
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Alice C. Fan
Assistant Professor of Medicine (Oncology) and, by courtesy, of Urology
Current Research and Scholarly InterestsDr. Fan is a physician scientist who studies how turning off oncogenes (cancer genes) can cause tumor regression in preclinical and clinical translational studies. Based on her findings, she has initiated clinical trials studying how targeted therapies affect cancer signals in kidney cancer and low grade lymphoma. In the laboratory, she uses new nanotechnology strategies for tumor diagnosis and treatment to define biomarkers for personalized therapy.
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Jonathan Fan
Associate Professor of Electrical Engineering
Current Research and Scholarly InterestsOptical engineering plays a major role in imaging, communications, energy harvesting, and quantum technologies. We are exploring the next frontier of optical engineering on three fronts. The first is new materials development in the growth of crystalline plasmonic materials and assembly of nanomaterials. The second is novel methods for nanofabrication. The third is new inverse design concepts based on optimization and machine learning.
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Shanhui Fan
Joseph and Hon Mai Goodman Professor of the School of Engineering and Professor, by courtesy, of Applied Physics
BioFan's research interests are in fundamental studies of nanophotonic structures, especially photonic crystals and meta-materials, and applications of these structures in energy and information technology applications
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Wendy Fantl
Associate Professor (Research) of Urology
On Leave from 08/13/2022 To 08/12/2024Current Research and Scholarly InterestsDr Fantl’s lab studies two key questions with unmet clinical need related to drug resistance and immunotherapy focusing on ovarian and kidney cancers. The lab applies multi-parametric single-cell proteomic technologies (mass cytometry aka Cytometry by Time-Of-Flight (CyTOF) and multiplex imaging (CO-Detection by indEXing (CODEX)) combined with specialized computational approaches.
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C. Garrison Fathman
Professor of Medicine (Immunology and Rheumatology), Emeritus
Current Research and Scholarly InterestsMy lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.
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Michael Fayer
David Mulvane Ehrsam and Edward Curtis Franklin Professor of Chemistry
BioMy research group studies complex molecular systems by using ultrafast multi-dimensional infrared and non-linear UV/Vis methods. A basic theme is to understand the role of mesoscopic structure on the properties of molecular systems. Many systems have structure on length scales large compare to molecules but small compared to macroscopic dimensions. The mesoscopic structures occur on distance scales of a few nanometers to a few tens of nanometers. The properties of systems, such as water in nanoscopic environments, room temperature ionic liquids, functionalized surfaces, liquid crystals, metal organic frameworks, water and other liquids in nanoporous silica, polyelectrolyte fuel cell membranes, vesicles, and micelles depend on molecular level dynamics and intermolecular interactions. Our ultrafast measurements provide direct observables for understanding the relationships among dynamics, structure, and intermolecular interactions.
Bulk properties are frequently a very poor guide to understanding the molecular level details that determine the nature of a chemical process and its dynamics. Because molecules are small, molecular motions are inherently very fast. Recent advances in methodology developed in our labs make it possible for us to observe important processes as they occur. These measurements act like stop-action photography. To focus on a particular aspect of a time evolving system, we employ sequences of ultrashort pulses of light as the basis for non-linear methods such as ultrafast infrared two dimensional vibrational echoes, optical Kerr effect methods, and ultrafast IR transient absorption experiments.
We are using ultrafast 2D IR vibrational echo spectroscopy and other multi-dimensional IR methods, which we have pioneered, to study dynamics of molecular complexes, water confined on nm lengths scales with a variety of topographies, molecules bound to surfaces, ionic liquids, and materials such as metal organic frameworks and porous silica. We can probe the dynamic structures these systems. The methods are somewhat akin to multidimensional NMR, but they probe molecular structural evolution in real time on the relevant fast time scales, eight to ten orders of magnitude faster than NMR. We are obtaining direct information on how nanoscopic confinement of water changes its properties, a topic of great importance in chemistry, biology, geology, and materials. For the first time, we are observing the motions of molecular bound to surfaces. In biological membranes, we are using the vibrational echo methods to study dynamics and the relationship among dynamics, structure, and function. We are also developing and applying theory to these problems frequently in collaboration with top theoreticians.
We are studying dynamics in complex liquids, in particular room temperature ionic liquids, liquid crystals, supercooled liquids, as well as in influence of small quantities of water on liquid dynamics. Using ultrafast optical heterodyne detected optical Kerr effect methods, we can follow processes from tens of femtoseconds to ten microseconds. Our ability to look over such a wide range of time scales is unprecedented. The change in molecular dynamics when a system undergoes a phase change is of fundamental and practical importance. We are developing detailed theory as the companion to the experiments.
We are studying photo-induced proton transfer in nanoscopic water environments such as polyelectrolyte fuel cell membranes, using ultrafast UV/Vis fluorescence and multidimensional IR measurements to understand the proton transfer and other processes and how they are influenced by nanoscopic confinement. We want to understand the role of the solvent and the systems topology on proton transfer dynamics. -
Ron Fedkiw
Canon Professor in the School of Engineering
BioFedkiw's research is focused on the design of new computational algorithms for a variety of applications including computational fluid dynamics, computer graphics, and biomechanics.
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Vivian Feig
Assistant Professor of Mechanical Engineering
BioDr. Vivian Feig is an incoming Assistant Professor in the Mechanical Engineering department, beginning March 2024. The Feig lab aims to develop low-cost, noninvasive, and widely-accessible medical technologies that integrate seamlessly with the human body. We accomplish this by developing functional materials and devices with dynamic mechanical properties, leveraging chemistry and physics insights to engineer novel systems at multiple length scales. In pursuit of our goals, we maintain a strong emphasis on integrity and diversity, while nurturing the intellectual curiosity and holistic growth of our team members as researchers, communicators, and leaders.
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Carl Feinstein
Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsAutism and Asperger's Disorder.
Genetically-based neurodevelopmental disorder, including Velocardiofacial Syndrome, Smith-Magenis Syndrome, Williams Syndrome, and Fragile X Syndrome.
Intellectual Disability (mental retardation) and psychiatric disorders.
Developmental Language Disorder and Learning Disabilities.
Sensory impairment in children, including visual and hearing impairment.
Psychiatric aspects of medical illness and disability in children. -
Jeffrey A. Feinstein, MD, MPH
Dunlevie Family Professor of Pulmonary Vascular Disease and Professor, by courtesy, of Bioengineering
Current Research and Scholarly InterestsResearch interests include (1) computer simulation and modeling of cardiovascular physiology with specific attention paid to congenital heart disease and its treatment, (2) the evaluation and treatment of pulmonary hypertension/pulmonary vascular diseases, and (3) development and testing of medical devices/therapies for the treatment of congenital heart disease and pulmonary vascular diseases.
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Jessica Feldman
Associate Professor of Biology
On Leave from 01/01/2024 To 06/30/2024Current Research and Scholarly InterestsWe are interested in understanding design principles within cells that contribute to the diversification of cellular form and function. Using a combination of genetic, biochemical, and live imaging approaches, we are investigating how the microtubule cytoskeleton is spatially organized and the mechanisms underlying organizational changes during development.
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Marcus Feldman
Burnet C. and Mildred Finley Wohlford Professor
Current Research and Scholarly InterestsHuman genetic and cultural evolution, mathematical biology, demography of China
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Dean W. Felsher
Professor of Medicine (Oncology) and of Pathology
Current Research and Scholarly InterestsMy laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.
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Stephen Felt, DVM, MPH
Professor of Comparative Medicine
Current Research and Scholarly InterestsHis research interests include infectious diseases, particularly zoonoses, and exploring techniques which promote the health and welfare of laboratory animals.
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Scott Fendorf
Terry Huffington Professor, Senior Associate Dean for Integrative Initiatives and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsSoil and environmental biogeochemistry
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Liang Feng
Associate Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsWe are interested in the structure, dynamics and function of eukaryotic transport proteins mediating ions and major nutrients crossing the membrane, the kinetics and regulation of transport processes, the catalytic mechanism of membrane embedded enzymes and the development of small molecule modulators based on the structure and function of membrane proteins.
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Russell D. Fernald
Benjamin Scott Crocker Professor of Human Biology, Emeritus
Current Research and Scholarly InterestsIn the course of evolution,two of the strongest selective forces in nature,light and sex, have left their mark on living organisms. I am interested in how the development and function of the nervous system reflects these events. We use the reproductive system to understand how social behavior influences the main system of reproductive action controlled by a collection of cells in the brain containing gonodotropin releasing hormone(GnRH)
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Katherine Ferrara
Professor of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly InterestsMy focus is image-guided drug and gene delivery and I am engaged in the design of imaging devices, molecularly-targeted imaging probes and engineered delivery vehicles, drawing upon my education in biology and imaging physics and more than 20 years of experience with the synthesis and labeling of therapeutic particles. My laboratory has unique resources for and substantial experience in synthetic chemistry and ultrasound, CT, MR and PET imaging.
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James Ferrell
Professor of Chemical and Systems Biology and of Biochemistry
Current Research and Scholarly InterestsMy lab has two main goals: to understand the regulation of mitosis and to understand the systems-level logic of simple signaling circuits. We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study. We also carry out single-cell fluorescence imaging studies on mammalian cell lines. Our experimental work is complemented by computational and theoretical studies aimed at understanding the design principles and recurring themes of regulatory circuits.
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David Fiorentino, MD, PhD
Professor of Dermatology
Current Research and Scholarly InterestsI am interested in all types of immune-mediated skin disease, with a focus on psoriasis and rheumatic skin disease. I co-direct a multi-disciplinary clinic dedicated to the care of patients with rheumatic skin diseases, such as lupus erythematosus, vasculitis, dermatyositis and scleroderma. I conduct multiple clinical trials and I participate in translational research with tissues obtained from a prospective cohort of patients with scleroderma, lupus, and dermatomyositis.
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Andrew Fire
George D. Smith Professor of Molecular and Genetic Medicine and Professor of Pathology and of Genetics
Current Research and Scholarly InterestsWe study natural cellular mechanisms for adapting to genetic change. These include systems activated during normal development and those for detecting and responding to foreign or unwanted genetic activity. Underlying these studies are questions of how a cells can distinguish information as "self" versus "nonself" or "wanted" versus "unwanted".
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Michael Fischbach
Liu (Liao) Family Professor
Current Research and Scholarly InterestsThe microbiome carries out extraordinary feats of biology: it produces hundreds of molecules, many of which impact host physiology; modulates immune function potently and specifically; self-organizes biogeographically; and exhibits profound stability in the face of perturbations. Our lab studies the mechanisms of microbiome-host interactions. Our approach is based on two technologies we recently developed: a complex (119-member) defined gut community that serves as an analytically manageable but biologically relevant system for experimentation, and new genetic systems for common species from the microbiome. Using these systems, we investigate mechanisms at the community level and the strain level.
1) Community-level mechanisms. A typical gut microbiome consists of 200-250 bacterial species that span >6 orders of magnitude in relative abundance. As a system, these bacteria carry out extraordinary feats of metabolite consumption and production, elicit a variety of specific immune cell populations, self-organize geographically and metabolically, and exhibit profound resilience against a wide range of perturbations. Yet remarkably little is known about how the community functions as a system. We are exploring this by asking two broad questions: How do groups of organisms work together to influence immune function? What are the mechanisms that govern metabolism and ecology at the 100+ strain scale? Our goal is to learn rules that will enable us to design communities that solve specific therapeutic problems.
2) Strain-level mechanisms. Even though gut and skin colonists live in communities, individual strains can have an extraordinary impact on host biology. We focus on two broad (and partially overlapping) categories:
Immune modulation: Can we redirect colonist-specific T cells against an antigen of interest by expressing it on the surface of a bacterium? How do skin colonists induce high levels of Staphylococcus-specific antibodies in mice and humans?
Abundant microbiome-derived molecules: By constructing single-strain/single-gene knockouts in a complex defined community, we will ask: What are the effects of bacterially produced molecules on host metabolism and immunology? Can the molecular output of low-abundance organisms impact host physiology?
3) Cell and gene therapy. We have begun two new efforts in mammalian cell and gene therapies. First, we are developing methods that enable cell-type specific delivery of genome editing payloads in vivo. We are especially interested in delivery vehicles that are customizable and easy to manufacture. Second, we have begun a comprehensive genome mining effort with an emphasis on understudied or entirely novel enzyme systems with utility in mammalian genome editing. -
Daniel Fisher
David Starr Jordan Professor
Current Research and Scholarly InterestsEvolutionary & ecological dynamics & diversity, microbial, expt'l, & cancer
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Dominik Fleischmann
Professor of Radiology (Cardiovascular Imaging)
Current Research and Scholarly InterestsNon-invasive Cardiovascular Imaging
Image Post-processing
Contrast Medium Dynamics -
Sean Follmer
Associate Professor of Mechanical Engineering and, by courtesy, of Computer Science
Current Research and Scholarly InterestsHuman Computer Interaction, Haptics, Robotics, Human Centered Design
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James Ford
Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNA damage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.
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Polly Fordyce
Associate Professor of Bioengineering and of Genetics
On Leave from 01/01/2014 To 08/31/2024Current Research and Scholarly InterestsThe Fordyce Lab is focused on developing new instrumentation and assays for making quantitative, systems-scale biophysical measurements of molecular interactions. Current research in the lab is focused on three main platforms: (1) arrays of valved reaction chambers for high-throughput protein expression and characterization, (2) spectrally encoded beads for multiplexed bioassays, and (3) sortable droplets and microwells for single-cell assays.
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Michael B. Fowler, MBBS, FRCP
Professor of Medicine (Cardiovascular), Emeritus
Current Research and Scholarly InterestsAdrenergic nervous system; beta-adrenergic function in, heart failure; drugs in heart failure.
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Emily Fox
Professor of Statistics and of Computer Science
BioEmily Fox is a Professor in the Departments of Statistics and Computer Science at Stanford University. Prior to Stanford, she was the Amazon Professor of Machine Learning in the Paul G. Allen School of Computer Science & Engineering and Department of Statistics at the University of Washington. From 2018-2021, Emily led the Health AI team at Apple, where she was a Distinguished Engineer. Before joining UW, Emily was an Assistant Professor at the Wharton School Department of Statistics at the University of Pennsylvania. She earned her doctorate from Electrical Engineering and Computer Science (EECS) at MIT where her thesis was recognized with EECS' Jin-Au Kong Outstanding Doctoral Thesis Prize and the Leonard J. Savage Award for Best Thesis in Applied Methodology.
Emily has been awarded a CZ Biohub Investigator Award, Presidential Early Career Award for Scientists and Engineers (PECASE), a Sloan Research Fellowship, ONR Young Investigator Award, and NSF CAREER Award. Her research interests are in modeling complex time series arising in health, particularly from health wearables and neuroimaging modalities. -
Paige Fox, MD, PhD, FACS
Associate Professor of Surgery (Plastic and Reconstructive Surgery)
BioDr. Paige Fox is Board Certified Plastic Surgeon who specializes in hand surgery, reconstructive microsurgery including facial reanimation, as well as peripheral nerve and brachial plexus surgery. She is an Associate Professor in the Division of Plastic and Reconstructive surgery in the Department of Surgery. She works with adult and pediatric patients. Her lab focuses on wound healing and nerve compression. She has clinical research interested in optimizing care of upper extremity and nerve disorders both in the US and internationally. Dr. Fox has a passion for sustainability and health care's effect on the environment. She is involved in efforts to green the OR and the clinics at Stanford.
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Christopher Francis
Professor of Earth System Science, of Oceans and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsMicrobial cycling of carbon, nitrogen, and metals in the environment; molecular geomicrobiology; marine microbiology; microbial diversity; meta-omics
